Ozempic and Upset Stomach: What Users Say (Page 4)
Reviews for Ozempic
- Ann...
- Taken for 1 to 6 months
- October 22, 2021
For Type 2 Diabetes "This is a horrible drug. I thought I was dying, my stomach hurt so bad. I'd be in a ball on the couch. I had headaches, constipation, vomiting, could not eat, lost 20 lbs so fast, my skin sagged. Do not take this medication."
- Sep...
- December 7, 2021
For Type 2 Diabetes "I have started Ozempic February 2020. I experienced severe stomach problems, constipation, my sense of smell became too sensitive. I couldn’t eat any kind of meat, eggs, or vegetables because the smell of them was revolting. Gradually, my intake was bread, cheese, and sweets, so weight loss was slow with a lot of carbs that were easy to digest. Since I had depression and previous reflux disease, my doctor kept telling me it is all in your head. I developed piles (hemorrhoids) because of the abuse of laxatives. Cramps in my large intestine were so severe that I begged my doctor I might have cancer. As I stopped Ozempic, I felt an enormous pressure leave my digestive system. Now I have another problem, I lost 8 kilos by Ozempic from February 2020 till October 2021. Two weeks after stopping Ozempic, I gained 4 kilos again, and I have an enormous appetite."
See also:
Repatha
Repatha is used to lower high cholesterol alongside dietary changes and to reduce the risk of major ...
Jardiance
Jardiance (empagliflozin) is used to treat type 2 diabetes, chronic kidney disease and reduce the ...
Mounjaro
Mounjaro (tirzepatide) is FDA-approved to manage type 2 diabetes in adults. It lowers blood sugar ...
Farxiga
Farxiga (dapagliflozin) is an oral prescription medication that may be given to certain adults with ...
Lasix
Lasix is a loop diuretic used to treat fluid retention from heart, liver, or kidney conditions, and ...
Xarelto
Xarelto (rivaroxaban) is a factor Xa inhibitor used to reduce the risk of blood clots and stroke in ...
Rybelsus
Rybelsus tablets are used to improve blood sugar control in adults with type 2 diabetes, and may ...
Zepbound
Zepbound (tirzepatide) is an FDA-approved weekly injection for weight loss and obstructive sleep ...
Trulicity
Trulicity is an injectable diabetes medicine that is used together with diet and exercise to ...
Frequently asked questions
- Mounjaro vs Ozempic: Which is right for you?
- Ozempic Side Effects to Watch For
- How do Ozempic, Mounjaro, Wegovy, Zepbound compare for weight loss?
- What are the long-term side effects of Ozempic?
- Jen...
- Taken for less than 1 month
- August 19, 2021
For Type 2 Diabetes "I was prescribed Ozempic for Type 2 diabetes to help lower my blood sugar and to help with weight loss. The first week wasn't so bad, just a little fatigued and some upset stomach problems. The second week it kicked in overtime and hit me like a brick wall. I had no energy at all. Stayed in bed because it's all I could do. My stomach was so upset and nausea, vomiting, and diarrhea were so bad, it ran like water. I became more dehydrated with less energy. I have 4 autoimmune diseases and this was the sickest I have ever felt in my life. I almost went to the ER and if not for Covid, I would have. It felt like someone had been feeding me rat poison. It's the worst feeling ever. I truly don't know how this drug was approved by the FDA. I plan to take myself off it. Weight loss and blood sugar need to be done in a healthier manner. Lose weight fast and easy has consequences."
- lcg...
- Taken for 1 to 6 months
- March 23, 2021
For Type 2 Diabetes "It has been a month on Ozempic. So far, so good. I have had stomach issues, but not severe. My appetite has changed, which is also helping. I've lost about 8 lbs. This week I went up to the 0.5, my sugar numbers are fantastic. I had an average of 145-160 for fasting, and I am now around 100-113. I am due for an A1C check in a couple of months, super curious to see the change. I am currently 6.6, I am hoping to be down to 6.0. The stomach issues do get better if you can get past the first 4 weeks. I also have heart disease, which stemmed from poor diet and uncontrolled diabetes. I will take the stomach issues for controlled sugar all day long. :)"
Are you taking this medicine?
Your review helps others make informed decisions.- fem...
- Taken for 6 months to 1 year
- September 23, 2023
For Type 2 Diabetes "Serious stomach issues, cramping, bloating, severe constipation, nausea, no appetite, rashes, pain in the upper and lower bowel, gas. Loss of too much weight, no taste for food. Have had previous trouble with colitis and diverticulitis but still prescribed this medication. Only have 1 kidney and now afraid it may be damaged. I have been on this drug for approximately 7-9 months. Now worried, but the doctor is not concerned enough to take me off this medication."
- Sha...
- Taken for less than 1 month
- May 26, 2018
For Type 2 Diabetes "My first week, I felt tired and had no energy. Mild, intermittent nausea. Guess that's the appetite suppressant part. After the first 3 days, I started getting quite a bit of stomach discomfort and diarrhea. Anything I ate or drank went right through me, as well as gas. Also, an unusual amount of belching. Hope this goes away soon and does not happen after every dose. I teach 4-year-olds, and it greatly affected my ability to do my job. My BS numbers are not much different."
More FAQ
- How long does it take for Ozempic to work?
- Wegovy vs Ozempic: Which is Right for You?
- How many doses are in an Ozempic pen?
- Anonymous
- Taken for 1 to 6 months
- June 9, 2023
For Cardiovascular Risk Reduction "I started on Ozempic when my health professional informed me I was pre-diabetic and had high cholesterol. Because I wanted to lose some weight, I asked her if I could try Ozempic, and she agreed to write the prescription for me. I've been on Ozempic since mid-April 2023, and I've had some success. I've lost 8 pounds since starting, but like many people, I've experienced nasty side effects, for example, sulfur burps, gas, and stomach discomfort. Although I've had these side effects, they have not been that serious, and I'm able to deal with them. I've tried increasing my dose to 0.5 mg, but the side effects got worse, and considering that my appetite and my cravings have decreased, I've decided to stay at 0.25 mg. I do find, however, that the day before my next dose, my appetite comes back. I need to be more mindful when that happens, and old habits are hard to change. I see a dietitian to help me plan balanced meals. In conclusion, I've stuck with Ozempic."
- did...
- Taken for 1 to 2 years
- August 13, 2024
For Type 2 Diabetes "Caused some G.I. issues (diarrhea, upset stomach), but after a few doses (0.5 mg) things improved. Still have bouts occasionally, but the reward (lower blood sugars and A1C) outweighs the negative. Seldom have a problem with the injection, but on occasion get a mild burning sensation, very mild."
- MZ_...
- Taken for 1 to 6 months
- May 31, 2023
For Type 2 Diabetes "I'm on my 4th week, and so far, the only thing I've experienced is stomach discomfort and diarrhea. My stomach usually turns the day of and after the injection, and I have a few days of diarrhea. I must admit that spicy food may have contributed to it a few times. My appetite is light, and my 5th dose will be an increase in milligrams. So, I don't know if the higher dose will come with more side effects. I inject myself in my upper arm because I have less fat there, and I want to get the full effects of the medication."
- not...
- Taken for 1 to 6 months
- May 3, 2023
For Type 2 Diabetes "I unfortunately had a very severe reaction to Ozempic. I usually do suffer side effects from most medications, but thought I would give it a try. The first two weeks were headache, general stomach ache, and constipation lasting 2 days after each injection. Weeks 3 and 4 got worse. Stronger reactions, lasting longer. Week 5, I started the double dose, and I was pretty ill for 2 days. Week 6 and 7 was rough, but I thought I could ride it out. Week 8 had me in emergency twice for diarrhea, vomiting, headache, and major dehydration. I was unable to eat or drink anything. I had to get rehydrated and be given anti-nausea meds on both occasions. I guess my body slowed the release of food so much I had a massive buildup to the point even a sip of water made me extremely nauseous. Ozempic is not for me."
- LLK...
- Taken for less than 1 month
- April 10, 2021
For Type 2 Diabetes "I was put on Ozempic for type 2 diabetes. The first week, I suffered bloating, sour stomach, and diarrhea. I was told it was temporary and it would get better. The next week, everything was worse and projectile vomiting was added. I took the third dose and nothing was better. I told the nurse about my experience and was told to stop the medication. I just don't know how long it will be before all the residual will get out of my body. I know this med works great for a lot of people, but not for me."
- Anonymous
- Taken for 1 to 6 months
- July 10, 2022
For Cardiovascular Risk Reduction "I started Ozempic because my weight has kept going up over the years. I’ve blamed it on menopause, getting older, and just having a borderline high blood sugar level and hypothyroidism. Had friends who were on Ozempic with great success, so I thought I’d give it a try. For me as well, it has been a game changer. I’ve lost 20 pounds, I look like myself before I married 30 years ago. I’ve had a few symptoms such as stomach cramping, some diarrhea on occasion, and I do have to cut my food intake almost in half. I don’t have sugar cravings at all anymore, which is a wonderful thing in itself. Overall, I have been very happy with it. I plan to reach my goal weight and cut back on my dosage to the minimum to maintain my new weight. This past weekend, I had to have an emergency appendectomy. I’m not sure if it’s related at all to the Ozempic, but thought I would report it here in case others have had a similar response. I definitely would be interested in knowing that."
- Her...
- Taken for 1 to 6 months
- April 28, 2021
For Type 2 Diabetes "I am a 54-year-old overweight male who started taking Ozempic 3 months ago to help control my type 2 diabetes and to lower my A1C. For the first 3 weeks, I took a 0.25 dose weekly and felt okay. Some occasional stomach cramps and nausea. For the past 2 months, I have been taking a 0.50 dose, and side effects have gotten worse. Loss of appetite, stomach pains, feeling nauseous, and uncontrollable diarrhea while sleeping. Yes, that's right... I have been pooping the bed. On the plus side, I have lost over 20 lbs, but at quite a disgusting price to pay. Time to either quit taking this or try something else. I now understand the commercials where the people say 'O.' It's because 'O, I pooped my pants again.'"
- Anonymous
- May 5, 2023
For Cardiovascular Risk Reduction "I made a review when I first started Ozempic. Now, I am on my second week and lucky to have no bad side effects, except for constipation. I have been taking natural laxatives, but they also give me stomach cramps. So, I am going to reduce the dose. I don't know how long I am staying on it. I will see my doctor in two weeks and see what she says. I am not obese, but my cholesterol and blood sugar were high. Also, I would like to lose 10-15 lbs. I have already lost 4 lbs, and I am happy with it. I have always been a healthy eater and now try to be more so. I am happy with it because my weight is more manageable now."
- Sar...
- Taken for 1 to 6 months
- October 30, 2022
For Cardiovascular Risk Reduction "I have been on Ozempic for 4 months now for weight loss. Initially, I had some GI side effects (bloating and stomach upset), but after a few weeks that mostly went away. My appetite is low (which is the intended effect), and I have not been enjoying meat as much, but otherwise, I am happy with the way this is going. As of now, I lost 14 pounds. Would recommend this medicine to everyone trying to lose weight, except for the fact that it is quite expensive. I had trouble finding a prescriber because Wegovy, which is FDA approved, is backordered everywhere. And Ozempic is the same medication, but not technically approved."
- FON...
- Taken for less than 1 month
- December 11, 2021
For Type 2 Diabetes "My doctor told me about a wonder drug called Ozempic. I am on the first dose, 0.25 mg. The first day had eye problems, stomach aches, dizziness, etc. The next day, I was not happy: eye problems, chest pain, cannot concentrate, afraid to drive my car. I will try all four doses, if problems remain, I will stop it."
- OVE...
- Taken for 6 months to 1 year
- March 22, 2025
For Type 2 Diabetes "Lots of stomach pain, gas, lots of nausea. This occurs before eating on a lot of occasions. Also, lots of symptoms of GERD after increasing dose from 0.5 to 1 mg. Ozempic does work for my diabetes, but the cost is high. I was given this as a cardiac-friendly medicine, but the GERD and excessive bathroom and stomach issues get the heart worked up."
- Mag...
- Taken for 1 to 6 months
- January 21, 2022
For Type 2 Diabetes "I've been using Ozempic for 2.5 months and suffered a lot from the first day I started using it. It was kind of okay, let's say it with side effects with 0.25 and 0.5, but when I got to 1 ml, I felt horrible. Dizzy, stomach aches, vomiting, horrific. And I lost maybe 1.5 kg in 2.5 months, so in my opinion, not worth it. I am going to go back on my meds for diabetes, eat healthier, and go back to the gym. A healthy way to lose weight and to feel like a human being and not sick in my stomach every single day."
- Ros...
- Taken for less than 1 month
- February 17, 2025
For Type 2 Diabetes "This is my 2nd week on Ozempic. I was already having some issues (possibly the flu or COVID) when I first started Ozempic. By the time I got to see my doctor, I had already been sick for well over a week, so no testing was done. However, after talking to my diabetes doctor and taking my second dose, I am fairly sure the Ozempic is causing me some stomach issues. Nothing major, just an upset stomach and running to the restroom. I am currently taking 0.25 units a week. I am going to stay at this dosage for about 4 weeks and see how my system adjusts. It is very simple to use. I was surprised that there were needles with my pen, and they are so tiny. I wish the ones I use with my Lantus were this small. I was down 10 lbs when I went to the doctor, but I don't think it was just the Ozempic. Like I said, I hadn't been feeling well already and not eating very much because of it. But I will take what I can get!"
- Ros...
- Taken for less than 1 month
- February 17, 2025
For Type 2 Diabetes "This is my 2nd week on Ozempic. I was already having some issues (possibly the flu or COVID) when I first started Ozempic. By the time I got to see my doctor, I had already been sick for well over a week, so no testing was done. However, after talking to my diabetes doctor and taking my second dose, I am fairly sure the Ozempic is causing me some stomach issues. Nothing major, just an upset stomach and running to the restroom. I am currently taking 0.25 units a week. I am going to stay at this dosage for about 4 weeks and see how my system adjusts. It is very simple to use. I was surprised that there were needles with my pen, and they are so tiny. I wish the ones I use with my Lantus were this small. I was down 10 lbs when I went to the doctor, but I don't think it was just the Ozempic. Like I said, I hadn't been feeling well already and not eating very much because of it. But I will take what I can get!"
- Per...
- Taken for 1 to 2 years
- December 26, 2024
For Type 2 Diabetes "Ozempic has helped me, so I do not have to take insulin. When I first started it, I had tummy aches, but now that I have been on it for the past three months, no problems with that. You do have to be careful about how much you eat, Ozempic has helped me regulate how I eat and what I eat. If you overeat, you may end up with a bad case of diarrhea, but that doesn't happen very often anymore. One more thing, if you come off the Ozempic, you may see a spike in your blood sugar. Overall, I really don't have a problem with taking Ozempic."
- Pau...
- Taken for less than 1 month
- January 25, 2023
For Type 2 Diabetes "I took one injection of 1 mg as prescribed. I have been sick for a week with severe constipation, nausea, dizziness, stomach upset/pain, acidity, gas bloating. I could not eat or sleep comfortably at night. This is very strong and mainly suppresses the appetite. I never had this much sickness from a drug."
- Bri...
- Taken for less than 1 month
- December 12, 2021
For Type 2 Diabetes "Doctor asked me if I wanted to switch from my weekly injection of Trulicity (been on Trulicity for over 4 years) and try Ozempic. He said that Ozempic was more effective. I agreed to try it. He asked if I wanted to start on a low 0.5 mg dose because of the adverse side effects that some people experience with their digestive system/stomach. I told him I have a pretty strong stomach and eat a lot of spicy/hot food, so I'd go for the full 1 mg dose. Started it on a Sunday (2 weeks ago) and my stomach did feel kind of lousy for the first 3 or 4 days. Pretty much went away after that though. I have been accustomed to giving myself a moderate dose of Novolog (16-20 mg depending on how high my blood glucose is) without eating anything when I check my glucose level. That has always worked well for me to bring my glucose down from say 220 to around 120 or 130. With Ozempic, doing that will cause my glucose to crash to 60 or 70."
- Win...
- Taken for less than 1 month
- March 19, 2025
For Type 2 Diabetes "Ozempic has made me not want to eat much at all. When I first started, I had stomach cramps, gastro, but that is slowly passing. I often feel tired and have to take an afternoon nap as I can’t keep my eyes open."
Are you taking this medicine?
Your review helps others make informed decisions.More about Ozempic (semaglutide)
- Ozempic consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (1,526)
- Drug images
- Latest FDA alerts (5)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- FDA approval history
- Drug class: GLP-1 Agonists (Incretin Mimetics)
- Breastfeeding
- En español
For Type 2 Diabetes "I've been on Ozempic 0.25 mg since last March. Had a lot of stomach problems for the first 3 months and stopped for a month to calm my stomach. Lost 16 pounds in the beginning, but that has come to a standstill. I have noticed, besides stomach issues, mood swings, mild depression I didn't have prior, fatigue, and still ongoing stomach issues. I will probably stop. While it notes there are cardiology benefits, for me, it's just not worth the side effects. My advice is to make sure you keep in touch with your doctor and tell them how you are feeling."