Semaglutide for Weight Loss (Obesity/Overweight) User Reviews (Page 5)
Brand names: Ozempic, Rybelsus, Wegovy
Reviews for Semaglutide
- Mim...
- Taken for 1 to 6 months
- September 19, 2023
"Wegovy is working great! Very important to hydrate and have a lot of fiber. Also, control your portion size; you cannot eat large portions. I'm following a strict 1300 calorie lifestyle change. From June 17, 2023, to present (Sept 19, 2023), I've lost 30 lbs. The injections are simple and virtually painless. I'm currently on 1.7 and I have little to no side effects. I inject every Saturday night before I go to sleep. I read that taking medication before bed reduces nausea and for me, it has worked. The only side effect is that I have absolutely NO desire to drink alcohol. The best side effect ever! I've already stopped taking blood pressure medication, cholesterol medication has been reduced to the lowest dose, and my A1C is out of the pre-diabetic range and within normal limits, and I'm only halfway to my weight loss goal. All medication has been stopped or reduced by my physician after blood work. Very happy!"
- Ano...
- Taken for 1 to 6 months
- August 10, 2025
"I took Ozempic previously and lost 35 lbs. Unfortunately, my insurance stopped covering it. I am now taking Wegovy and have been for seven weeks. I have since lost a grand total of four pounds. Yes, FOUR. When I was on Ozempic, I had lost twice that amount by the seventh week. I have been exercising and changed my eating habits as well. FOUR pounds. While on Ozempic, I ate what I wanted and did not exercise. Not sure of the difference, but I am quite frustrated. This stuff isn’t cheap!"
Frequently asked questions
- Ozempic Side Effects to Watch For
- Wegovy vs Ozempic: Which is Right for You?
- Tirzepatide vs semaglutide: How do they compare?
- Which GLP-1 drug is best for weight loss?
- Bit...
- Taken for 6 months to 1 year
- March 23, 2025
"I started Wegovy in April 2024. I was 193 lbs at just between 5’1”-5’2.5. I had tried everything, but food noise and the fact that being so short, the calorie intake had to be so low to lose weight. Anyway, the first thing I noticed was a bit of nausea. That went away after a few days. I have had very minimal side effects. Sometimes a little nausea, constipation, or diarrhea. Nothing to really disrupt my life. For the first time in my life, I actually can tell when I am full. My IBS has been almost non-existent. I’m more awake. I have fewer sweet cravings. The food noise is still there, but my stomach is able to signal my brain that if I eat more, I will feel sick. I have lost to date 4/2024-3/2025, 63 lbs. I am just about to hit my normal weight goal. I knew how to lose the weight. I am someone who has a very difficult time shedding the weight with exercise and diet. I am super grateful for this opportunity to prove that a drug works so well."
- XXO...
- Taken for less than 1 month
- June 11, 2023
"I experienced vomiting within one hour, swelling of the throat, and difficulty swallowing, which has not stopped since the first and last dose on Sept 6th, 2023. Now hypersensitive to all regular daily medications and taking Benadryl several times per day."
- Nur...
- Taken for 1 to 6 months
- July 15, 2023
"Ozempic for weight loss is AMAZING! I have tried everything for weight loss since 1985. Ozempic by far is a miracle for me. It immediately blocks cravings, appetite, and thoughts about food! I started June 2, 2023 and today, July 13, 2023, I lost 22.3 lbs. This is a 6-week success story! I took 0.25 for the first week and then 0.5 weekly on Sundays. I have stayed with Weight Watchers, mainly selecting 'free foods'. If you are eating out with friends this summer, remember that rich, high-fat content foods will give you immediate abdominal distress (cramps, diarrhea). So, I've learned to go through restaurant menus and find something less distressful to eat so that I can enjoy time with friends and family. I have Zofran for nausea, but for me, the nausea passes and I do not use anything for nausea. Stay active at least walk! It's free! Keep drinking water and add a packet of electrolytes due to this extreme heat this summer! Check-in with my doctor on a regular basis."
- MM...
- Taken for 1 to 6 months
- December 22, 2022
"Wegovy has agonizing side effects. I had to quit after 2 months. Constant, uncontrollable vomiting, I vomited at work and while driving (which was horrific and dangerous). I essentially became bulimic and afraid to eat. I lost 20 pounds but put half of it back right away. Not worth the agony."
More FAQ
- Why am I not losing weight on Ozempic?
- Does Ozempic cause muscle loss and how to prevent it?
- How much does semaglutide cost?
- Where and how should Ozempic be injected?
- AMa...
- January 2, 2022
"I’m on Week 15 of treatment and have lost nothing. On the first dose of 0.75 mg, I experienced heartburn, fullness, and zero appetite for 5 days. I was hopeful that it had finally started to work. On subsequent doses of 0.75 mg and 1 mg, and now on 1.7 mg, I’ve felt no effects from Wegovy. I’ve tried switching injection sites from my abdomen to my arm with no effect."
- Bar...
- Taken for 1 to 6 months
- March 24, 2023
"I have been taking Ozempic for six weeks. This will be my second week at 0.50 mg, and I have lost 10 lbs. At 0.25 mg, I had minor nausea and was very tired but felt fine otherwise. After my first 0.50 mg injections, I could not drink, eat, or do anything for the first day. I had a lot of nausea and felt like I was going to be sick constantly. By day 3, I had to go to the bathroom about nine times, which was good because constipation is a real thing with this medication. By day 4 and on, I felt perfectly fine. I do watch what I eat, and the medication has cut my food intake by half. You have to pay attention to what your stomach is telling you."
- Mic...
- Taken for 1 to 6 months
- June 7, 2023
"I had a horrible experience. Abdominal pain going to the back. Constant nausea. Depression - very strange feeling, almost like an out-of-body experience. For the first time, I found myself HATING my body. Extreme tiredness. Difficulty focusing. Gained 9 pounds in 3 weeks. Constant headaches."
- Hit...
- Taken for 1 to 6 months
- June 27, 2024
"Started Wegovy on May 11th at 0.25. I'm on my 4th injection of 0.5 and moving up to 1.0 next week. Started at 228 lbs. I'm down to 213. No side effects. I have to eat a small dinner and not too close to bedtime or I get heartburn. Slow and steady wins the race. Wegovy is the most effective appetite suppressant I have ever used, and best of all, no jitters or sleeplessness."
- Pam...
- Taken for 1 to 6 months
- April 24, 2025
"I have been on Wegovy now for about 5 months. I had weighed 340 lbs when I started Wegovy. I now weigh 280 lbs, I have lost 60 lbs so far. It took me 3 years to get on Wegovy through the Veterans Affairs. I am so glad this drug has been approved. I have lymphedema, and I have hardly any swelling. My cholesterol and blood pressure are down. I am feeling proud of myself for pursuing getting on Wegovy."
- Sup...
- Taken for 6 months to 1 year
- January 4, 2022
"Pros - I've been on Wegovy for 7 months. It started working right away. Lost between 8-15 lbs a month. It mostly has affected my appetite (not feeling hungry). Have lost 65 lbs thus far. Cons - nothing noticeable until I made it to the 1.7 mg dosage, and it got worse on the 2.4 mg. Severe diarrhea and cramps a day after eating. I noticed this became more regular after the 2.4 mg dosage. It happens 4-5 days after the injection, only for it to clear up after I give myself the next injection. Any bismuth anti-diarrhea helps to clear this, but you have to remember to take it with almost every meal."
- Jac...
- Taken for 1 to 6 months
- October 1, 2023
"I love it! Wegovy did what I needed it to do, it calmed my appetite. I had zero side effects. I lost twenty pounds in one month. I only have one problem, I can no longer get Wegovy in my needed dosage of 0.25 mg. I will patiently wait for the manufacture of Wegovy to catch up to the demand for their product because it works that well for me. Thank you for creating a product that has worked as advertised."
- Anonymous
- Taken for 1 to 6 months
- November 7, 2023
"I love the effects of Wegovy, however, my stomach felt upset the whole time I took it. I lost a lot of weight, pretty quickly. It happened so fast; I could not keep up with clothing size changes. I lost about 50 pounds in 3 months. I tried to eat, but the weight kept coming off. I would recommend a probiotic to help with the stomach issues, but overall, I am happy with the experience."
- 188...
- Taken for 1 to 6 months
- May 17, 2023
"Started Wegovy 3 months ago using the gradual phase-up method. From 0.25 mg dose for 4 weeks to 0.50 mg dose for 4 weeks, then 1.0 mg dose for 4 weeks. During the initial phase, I experienced mild nausea and some stomach irritation. With each increase, the symptoms got worse until finally, at the full 1.0 mg dose, I was so sick I thought I had stomach flu for 2 weeks continuously. The belching was horrible. The nausea caused uncontrollable vomiting, and I had frequent diarrhea. After 3 months, I lost 12 pounds and felt horrible every day. I've now reduced the dose to 0.5 mg but still suffer from nausea and stomach upset. I might cut back again, but I'm thinking I will quit. The way I feel all the time is horrible! I'm thinking I lost weight because of all the vomiting. Not recommended."
- Jan...
- Taken for less than 1 month
- January 9, 2023
"Took my first 0.25 mg Wegovy dose yesterday. I felt nauseous about an hour later, but within 2 hours, I started vomiting. For the next 16 hours, I dry heaved throughout the day and night. I couldn't even keep water down. It hasn’t been a full 24 hours yet since I took the shot and feel horrible, hoping that these side effects will stop soon. There is no way I’m taking another shot next week."
- Ran...
- Taken for 6 months to 1 year
- May 7, 2025
"I have been taking Wegovy for 8 months now. My start weight was 287 lbs, and now I am down to 230 lbs. My goal when I started was to get down to 220 lbs. I thought that would be impossible, but I am 10 lbs away from my goal, down 57 lbs and still counting. Very happy with Wegovy."
- anx...
- Taken for less than 1 month
- March 2, 2023
"I started taking Wegovy 2 weeks ago. The first week was okay, but in the second week, I started experiencing really bad anxiety. I wish I could be like other people and just get regular side effects. So far, I have lost 10 lbs."
- Me ...
- Taken for 1 to 6 months
- January 25, 2022
"Nausea, diarrhea, constipation, sulfur burps, fatigue, loss of appetite, super sensitive to smells, I have to make myself eat enough. It's like morning sickness, only it's 24/7. Zofran helps for about 6 hours. Cannot tolerate much besides chicken broth and Brussels sprouts. No fried, fatty, oily, spicy foods. Need to stay hydrated with water. Ginger ale helps. I'm up to a 1 mg dose and 14th week. This nausea is constant and impacts my daily routine significantly. However, it is the only effective weight loss option that's worked in 26 years of diets and exercise and eating healthy. I will not give up. The weight is killing me, and I needed this medication. I started at 221 lbs. and now I'm at 194.3 lbs. BMI is close to pre-obesity, and I know I'll cry the day I hit it. Full disclosure, I'm disabled in part due to my weight. There is no way I could have worked and taken Wegovy with the severity of my nausea and fatigue. But the mobility and breathing issues are improving."
- Abe...
- Taken for 1 to 6 months
- November 15, 2021
"Started out with .25 mg. I did that for four weeks and only felt slight nausea after the injection. Today, I bumped up to the .50 mg dose, and within five hours I was nauseous. I finally vomited, and I feel better, but have no appetite now. Nothing sounds good. I’m also sleepy. So far, the weight loss is only about five pounds. If I stay nauseated, it’ll probably increase drastically, but what a dumb way to live! I hope it’s temporary. I could be sick once a week and survive if I get decent weight loss. I am also fairly active, and I exercise 4-5 times a week. I don’t have a thyroid because of cancer nine years ago."
- SoH...
- Taken for 1 to 6 months
- June 30, 2022
"One word - amazing. I was so skeptical when starting this medication. I thought it would be just like everything I've tried before, but it's not. It works. Two months in and 20 pounds down. It's like magic! I have had some brief periods of nausea, but I drink some ginger ale and it helps a lot. I read that this medication would be a game changer for weight loss, and it has not disappointed."
- TED...
- Taken for 6 months to 1 year
- September 9, 2023
"I have been taking Ozempic for 9 months. I am 74 years old, and a workaholic. I simply do not have time to exercise. I am at my computer working between 18 and 20 hours x 7 x 365. This will not change - ever. I got up to 274 lbs. I weigh once weekly. Today I weighed 191 lbs., or a loss of 83 lbs. over the duration - or about 30% of my body weight. Some slight dizziness from time to time which has diminished considerably after the 2nd month. Bad diarrhea for 72 hours after each injection until I discovered this medication does not like fat/grease/fried food of any type - then, some manageable diarrhea thereafter. Dosage .5 mg. Extraordinarily easy to use."
- Jen...
- Taken for less than 1 month
- January 3, 2022
"I started this weight loss journey with Wegovy 4 days ago. No nausea, but definitely have some diarrhea starting the second day. I will continue with the treatment unless the side effects change or worsen."
- Mar...
- Taken for 1 to 6 months
- June 10, 2023
"I took it for two months, and I was very happy to lose 20 pounds so fast. After I stopped it, I regained everything back and even more. The sad news is I got gallbladder problems from Ozempic, and my gallbladder has to be removed. Not worth it."
See also:
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- Drug class: GLP-1 Agonists (Incretin Mimetics)
- Breastfeeding
"I had been on this drug for 4 months. Typical escalation dose until month 4, I stayed on the 1 mg. The side effects were rough since increasing to 1 mg. So much nausea, worsened reflux, constipation, bloating, burping, and indigestion. I vomited once, but there were a few times I almost did. In the last few weeks, I noticed hair loss. Noticed skin tags that I have never had...like 3 grew since the med. Weird. Oh, and I had serious issues with certain smells. I had to change out the hand soaps in my house 5 times. If I smell rubbing alcohol, I am instantly nauseous. Just looking at the Wegovy box before injecting would make me dizzy and nauseous. So weird. Difficult to eat healthy on this med due to side effects, and only able to tolerate simple carbs, low-fat diet. Also hard to work out when feeling so nauseous...so didn't think it was contributing to my health. Has not really contributed to weight loss, and appetite is almost the same as before med."