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Semaglutide for Weight Loss (Obesity/Overweight) User Reviews (Page 3)

Brand names: Ozempic, Rybelsus, Wegovy

Reviews for Semaglutide

Commonly mentioned side effects
  • Fin...
  • Taken for 1 to 6 months
  • July 5, 2022

"57-year-old on this for 3 1/2 weeks. I'd like to tell you how much I lost (was 4 pounds at 3 weeks), but I am so constipated for 4 days I cannot be sure what my real weight is (it could be 6 pounds now). Get a telemedicine provider to send you a vial of semaglutide (not the pre-loaded syringes) and use an insulin syringe to administer 1/2 the dose on one day with an ODT Zofran, then take the second half of the dose 24 hours later with another ODT Zofran. I administer in my outer thigh, like you would give insulin. The provider will tell you exactly how many 'units' to administer per week, just cut it in half, say Saturday and Sunday. Take a stool softener on Sunday, which I forgot to do this week! I have had zero gastrointestinal issues, no nausea, no vomiting. The Zofran may be causing some of the constipation, and I don't consider this a real issue, just a minor side effect with an easy fix. I am a Nurse Practitioner, so I have been watching everything for real side effects. I'll update."

10 / 10
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  • Mik...
  • Taken for 1 to 6 months
  • March 21, 2022

"Drug has been life-changing. When I began, I was 6'3'' and 357 lbs. Today is exactly 4 months in, and I'm down 60 lbs exactly. Blood pressure meds cut in half, discontinued Lasix and potassium pills. Currently taking 2.4 mg/weekly. My side effects have been relatively non-existent. Early on, some gastro upset and heartburn, but all went away with time."

10 / 10
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  • jmm...
  • September 27, 2022

"For me, it is a miracle drug! I have had no side effects and have been on it since December 2021. I was trying other medications that helped a little, but I was stuck teetering between 190-195 and could not pass that. As soon as I started Wegovy, the weight started to come off. I am now right around 160, and I am close to my goal. I am also 60 years old, which makes weight loss even more difficult. I highly recommend this treatment!"

10 / 10
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Frequently asked questions

  • Mar...
  • Taken for 6 months to 1 year
  • January 5, 2024

"I started Wegovy on 05/01/23. I weighed 312 lbs and I'm only 5'8" tall. As of 01/01/24, I am down 80 lbs and still going. I've had no side effects and my plan is to lose 125 lbs. The shot is painless and easy to inject. I honestly feel like I lost a whole person. My A1C went from 6.4 to 5.2. I recommend Wegovy to anyone who needs to lose weight..."

10 / 10
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  • Lal...
  • Taken for 1 to 6 months
  • June 10, 2023

"I started 3 weeks ago, and every Monday I inject myself with a 0.25 mg dose. I started this medication because at age 47, even though I tried so hard to exercise and diet, my weight was a roller coaster ride and I would bounce back to my heaviest weight. My weight when I started was 170 lbs, which was 3 weeks ago. After a week, I am down to 159 lbs, then the second week 157 lbs. I weighed myself yesterday and I am down to 155 lbs, that's 15 lbs less. The first week I had a little heartburn, and the second week I was a little dizzy because you can go a day without being hungry at all. By the end of the second week, I had no side effects at all. I am surprised that again I can go a day without being hungry at all, but of course, I force myself to eat something, even with food, I will eat but will be so full easily. I take protein shakes daily as my meal replacement. I'm taking fiber (gummies) so I can go to the bathroom with no problem, and it helps a lot. Overall, I am pretty happy with the result."

8 / 10
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  • Lor...
  • Taken for less than 1 month
  • October 3, 2023

"I was prescribed Wegovy for weight loss purposes. I’m 5’11, 225 pounds, with a BMI of 31%, so I can be considered obese. I’ve been on it for one week and have lost 7 pounds. I’m starting with the lowest dosage (0.25). First of all, the injection was completely painless (for me). I also inject Humira bi-weekly, so maybe I’m just used to it, but I was shocked to feel absolutely nothing. I questioned if I was doing it right, it was so painless. Do not let some testimonials scare you! I did a lot of research while waiting for the drug to come back into stock. 90% of what I read were complaints about vomiting, diarrhea, some people getting so sick they had to go off of it. Some of these reviews were written after only a week or two of the drug usage. So far, my personal experience has been completely different than what I’ve read. That could change as I go up in dosage. As of right now, the only side effect I’m experiencing is a complete lack of appetite."

8 / 10
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  • Eri...
  • Taken for 1 to 6 months
  • March 29, 2023

"I've been on Wegovy for a little over a month now. My first injection of the 0.5mg dose was on Friday (3/24/23). The weight loss has been fairly slow but steady. The main thing that I've noticed is that it makes me feel full after I eat. I know it sounds strange, but for some reason, I've never felt hungry or full-I ate when people told me and didn't stop eating until my plate was clean since I was a kid. Now, after I eat a bit, I feel full and stop eating. I've learned to be choosier with what I eat, opting for healthy things, protein and fiber, and less fat and carbs. No crazy fad diets or anything, just being more mindful. My injections are on Fridays, and I've noticed that Sundays are the worst days, but after 2 weeks on a dose, the side effects are pretty minimal. Just started the 0.5mg dose and so this past Sunday was bad, but my doctor gave me a PRN script for Zofran to help with nausea. I hope this review helps someone."

8 / 10
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More FAQ

  • JML...
  • Taken for 1 to 6 months
  • April 12, 2024

"I started Wegovy last month. Did all 4 doses of the 0.25 and took my first 0.50 yesterday. The first 0.25 injection I was vomiting and had a headache, but it only lasted one day. No other issues. As far as weight, I am 5'5'' and at my doctor's appointment I weighed my highest ever at 195 lbs! After the 4 doses of the 0.25, I am already down to 180 lbs! I am not exercising. Wegovy cut my appetite so much that I literally had to force myself to eat; I'm not complaining though! So now that I have started on the 0.50, I'm interested in seeing if I continue to drop. 15 lbs is a huge loss in one month on the 0.25 and I know it isn't typical, but it really has been a great experience for me. I will update next month after I take my last dose of the 0.50. I would definitely recommend Wegovy."

10 / 10
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  • eri...
  • Taken for 1 to 6 months
  • December 20, 2023

"I tried everything, almost getting gastric sleeve surgery. Thanks to my cardiologist, even my heart is fine, he doesn't want to give me clearance for the operation. He recommended Wegovy. I think this is the best decision I ever made. I started on November 2nd, 2023, and until now, December 20th, I have lost an incredible 30 pounds. I now eat only two times a day. I used to eat lots of sweet stuff, but not anymore. No more late eating. I eat very small portions and I feel full all day. I love you, Wegovy, it's real. I am on a 1mg dosage. I was 331 pounds and now I am 301 pounds, with a goal to lose 40 more pounds by July. Good luck everyone, there's a chance because of Wegovy."

10 / 10
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  • Shy...
  • Taken for 1 to 6 months
  • November 1, 2021

"Been on Wegovy for 7 weeks. Lost 14 pounds. 2nd week into 0.50 mg. It’s a little rough on my stomach. Taking prescription for nausea which happens the day of the injection. Feel tired and occasionally get severe abdominal pains. I can’t eat much and have to really watch the types of food. No greasy foods or spicy or heavy. The intestinal pains were very severe after eating wrong foods. I’m happy with the weight loss but the side effects are rough."

8 / 10
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  • Kel...
  • Taken for 1 to 6 months
  • May 4, 2023

"I have been on Wegovy for almost 7 weeks and have lost over 22 lbs. From the moment I took the first injection, the food noise was gone. At times, it feels like progress is slow, but in truth, the progress has been steady. I have not started dieting or exercising, I am focusing on eating healthier and listening to my body for signs that I am full. I have heard of bad side effects, though I personally have not experienced any. Prior to this medication, I have lost, gained, and relost 50-100 lbs over and over again."

10 / 10
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  • Oze...
  • Taken for less than 1 month
  • May 14, 2023

"With just one 0.25 mg dose, I became very ill. Relentless nausea, vomiting, and explosive diarrhea, as well as unbearable stomach cramps. Needed to go to the ER for fluids and to check for pancreatitis. It’s now been 9 days since my first dose, and I still have relentless diarrhea, nausea, and disabling fatigue. I don’t want to eat. I didn’t want to take it in the first place but was ambushed by my kidney doctor. She told me that using Ozempic was a no-brainer and that I would just have a bit of nausea. If you have any gastrointestinal symptoms when taking any medicine, I would think three times about it before using it. I have read it can take up to a month for it to be flushed out of your body, but I am hoping and praying that these horrible side effects stop real soon."

1 / 10
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  • Tou...
  • Taken for less than 1 month
  • March 14, 2023

"I am on my 3rd 0.25 dose of Wegovy. I feel terrible most of the time. I have lost 5 lbs and am definitely not hungry due to nausea. My prescriber will not prescribe Zofran with Wegovy because she feels nausea that severe should be considered a negative side effect and the medication stopped. That's reasonable. I read the reviews before I began the med and take Omeprazole daily, as well as Miralax. I am 57, menopausal, and used to feel really good most of the time. Sadly, this med is not worth the side effects for me. I really, really wanted to tough it out, but as a nurse, I feel it's creating problems that I did not have before taking this medication. The nausea is constant, the belching/burping is so frequent that it's embarrassing, stools are like a rock, and the worst feeling is chest tightness. I had so hoped I would be one of those without adverse side effects, but I am not."

3 / 10
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  • poi...
  • Taken for less than 1 month
  • April 3, 2023

"Been on Wegovy for half a week. For my first injection, I used the upper right side of my stomach. Within an hour, I had a bit of shooting pain in my left mid-back section. I was a bit concerned but didn't say anything to anyone about it as I figured it was just my body getting used to a new chemical. I'm now on day 3, and no pain anywhere, no nausea, and feeling pretty great. I am a little concerned about not understanding exactly what my caloric intake 'should' be but will discuss it with a dietitian. My dosage was the starter 0.25 mg, and my starting weight is 228 lbs. Let the journey begin! Already got past one of the biggest hurdles, namely doing the injections myself. The needle is super small, and didn't leave any marks or blood! Super fast, and recommend it to the 'needle-adverse' folks. I am very glad that it is only once a week though."

8 / 10
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  • Wag...
  • Taken for less than 1 month
  • April 5, 2023

"I took my first shot of 0.25 five days ago. I was extremely nervous about taking it due to all of the negative side effects that I read others have had. I decided to inject in my upper thigh late on a Friday afternoon so that if I did feel sick, I had the weekend to take it easy and deal with it. The injection was painless and very easy to administer myself. I honestly noticed no side effects after taking it, other than not thinking about food as much and wanting to eat a little less. I did push the boundaries on the third evening after taking it, and I did have bad nausea, I actually vomited and felt generally ill for about 16 hours (not bad enough to not work though). I pushed the boundaries by overeating air-fried chicken wings (no sauce) that were a bit more greasy/oily than normal. Those really set me off, and I realized that I: 1. can no longer eat any type of greasy food and 2. cannot eat too much. As long as I stick to my normal healthy, low-carb diet, I feel just fine (so far)."

9 / 10
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  • Bon...
  • Taken for less than 1 month
  • June 10, 2023

"Honestly, I have never been so sick in my life. 1st and only dose of Wegovy made me so incredibly sick. I have been in the hospital twice for excessive dry heaving. There is no stopping the symptoms. I had short-term relief with IV sedatives and anti-nausea medications. Still a week later, now at home throwing green bile. I will never recommend it to anyone."

1 / 10
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  • Hig...
  • Taken for 1 to 6 months
  • April 18, 2023

"I was worried about side effects with this medication, but I have not had any. So far, I have lost 16 lbs in two and a half months, with diet and exercise. I started with the 0.25 mg dose, and I am now on the 1 mg dose. I would recommend it to others who want to try it."

10 / 10
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  • Big...
  • Taken for 1 to 6 months
  • April 24, 2023

"I have been on Wegovy for over a month now. It has been a life changer for me. Very few side effects. I have way more energy, I can fit into clothes that were so tight I couldn't wear them, and I have fewer aches and pains. My mindset is so different. I am 5'11'', started at 263 lbs. (obese). I have lost almost 15 lbs. This stuff pretty much keeps those hunger cravings away. I have changed my eating habits as well. I only eat fruits, veggies, and salads. I do plan on going back to some of my other favorites, but for now, I'm sticking to no pasta, pizza, bread, or desserts. I only eat between the hours of 6 am to 3 pm. I have been walking around a half mile per day on my lunch breaks. I do not eat much, it seems like I get full very quickly. Another benefit is that I have bitten my nails my entire life, and since starting Wegovy, I have not touched them. It's quite unbelievable."

10 / 10
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  • Kir...
  • Taken for 1 to 6 months
  • February 3, 2022

"I'm on 2.4 now. Started yesterday and still have pretty bad nausea. It's the worst it's been. Before, it was quite negligible or non-existent. So far, I've lost 21 lbs in 4 months. I was 216, now 195 and I am 5'4'. I still have a long way to go. I started working out and started a vegan diet in January to improve my cholesterol. I know it's tough. I have read so much about it and my expectations were high, like all I need to do is take this injection and the weight will fall off! This will fix all of my problems! I'll find true happiness! But...that's not the case for most people, including me. My provider said that some of her patients have seen no results. She said a 20 lb weight loss is right on track for me and more sustainable than the amazing results some are seeing (though everyone is different). Remember: we are more than our weight. And there is no one answer. If you are taking this and it's not working, it's not you."

8 / 10
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  • usm...
  • Taken for 1 to 6 months
  • November 29, 2022

"At this time, I’m on my 5th week of the maintenance dose. The only side effect I’ve had is occasional constipation, but as a 25-year medical professional, I know how to deal with it medically and in conjunction with my VA doctor and pharmacist. At times, I would get hypoglycemic, but again I knew how to combat that. At this dose, I find myself somewhat more fatigued but I can deal with that. Cat naps usually do the trick. I started at 393 and 6’3”. I’m 56 years old. I’m down to 349 since I started, which for me is great. I have critical low testosterone and can’t take testosterone due to my history of pulmonary embolisms. So, I don’t mind losing only 2 pounds a week. I can now walk so much better and farther. I’m 95% VA disability rated, and I’ll tell you, I feel and look so much better after starting to use Wegovy. The VA truly cares for us veterans no matter what you hear. Stay blessed and hang in there."

10 / 10
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  • Hel...
  • June 19, 2023

"After 1 year of taking this, I began suffering from severe abdominal pain. A couple of months later, while watching TV, I heard an Ozempic commercial that included warnings about gallbladder problems and pancreatitis. I immediately stopped using it and went to my doctor. I had to have my gallbladder removed. I gained the 50 pounds back that I had lost the previous year. Although it was effective, it was not worth the side effects."

1 / 10
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  • TBH...
  • Taken for less than 1 month
  • February 25, 2023

"Started 2/23/23. 0.25. 64 years old, H 5/6, W 217. The only side effect is dizziness when standing up, which subsides within a minute or two. That seems to be hypoglycemia. As of today, 2/26/23, it has definitely curbed my appetite. I will check back in a month to let you know my progress."

8 / 10
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  • Dot...
  • Taken for less than 1 month
  • April 5, 2023

"I'm a 38-year-old man with type 2 diabetes and overweight. I was on metformin for three years and followed a good diet and exercise regime, but I couldn't lose weight. Although my blood sugars were perfect on metformin, weight was my issue. My doctor prescribed me Ozempic 0.25 mg, and I was very worried about the side effects. However, I started it recently anyway and injected it in the upper thigh once weekly. I had no issues other than constipation, which I overcame with laxatives and increased water intake. My appetite was reduced by 90%. I used to overeat, but now I can only manage two small meals a day. It's really working so far, but it's still early days. I'm in Ireland, and it costs €150 a month for four injections, which are covered by my medical card. I'll provide an updated review in three months to report how it has helped me lose weight on the scales."

9 / 10
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  • Jah...
  • Taken for less than 1 month
  • April 16, 2023

"So far, so good! Only on the 3rd day on it, but I'm loving it. On .25 mg dose to start. I'm female, 5'4", 215 lbs, and I'm looking to drop about 40 lbs with it. Very mild stomach discomfort here and there, but it's barely noticeable the vast majority of the time. When I first injected, I felt that my heartbeat got quicker for a little bit, but it subsided in an hour or two. I don't crave junk food anymore. I feel like I'm always full, and I have an increased desire for whole foods. I'm not going to increase my dose until I feel the beneficial effects subsiding, I'm taking it very slow to avoid side effects. Will check back in after a month or two, I'm very optimistic!"

10 / 10
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  • Les...
  • Taken for 1 to 6 months
  • January 14, 2025

"It's been great-I'm 53 years old, and I've been taking it since August. I've lost 30 pounds with no side effects. I take a 0.5 mg shot once a week, and I feel better than I have since before my last pregnancy 13 years ago. I tried everything to lose weight, and it just wouldn't come off. I have a family history of heart disease that includes my father having his first heart attack at 36, resulting in open-heart surgery, and his death at 49 from another heart attack. When I was 50, I was diagnosed with high blood pressure and high cholesterol, plus I weighed 230 pounds at 5'4" tall. I asked my doctor for a couple of years to prescribe a semaglutide, but because it was only really available for diabetics, she refused. When Wegovy was cleared for weight loss, she agreed to let me try it. It has been life-saving, I think."

10 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.