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Semaglutide for Weight Loss (Obesity/Overweight) User Reviews (Page 3)

Brand names: Ozempic, Wegovy, Rybelsus

Semaglutide has an average rating of 7.3 out of 10 from a total of 581 reviews for the treatment of Weight Loss (Obesity/Overweight). 63% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Semaglutide

  • Bonnie
  • Taken for less than 1 month
  • June 10, 2023

Wegovy (semaglutide) "Honestly, I have never been so sick in my life. 1st and only dose of wegovy made me so incredibly sick. I have been in the hospital twice for excessive dry heaving. There is no stopping the symptoms. I had short term relief with IV sedatives and anti nausea medications. Still a week later now at home throwing green bile. I will never recommend to anyone."

1 / 10
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  • Lala...
  • Taken for 1 to 6 months
  • June 10, 2023

Wegovy (semaglutide) "I started 3 weeks ago and every Monday I inject myself with a .25 mg dose. I started this medication because at age 47 even though I tried so hard to exercise and diet my weight was a roller coaster ride and I would bounce back to my heaviest weight. My weight when I started was 170 lbs which was 3 weeks ago. After a week I am down to 159 lbs, then second week 157 lbs, I weigh myself yesterday and I am down 155 lbs that's 15 lbs less. The first week I had a little heartburn, and the second week was a little dizzy because you can go a day without being hungry at all. End of the second week I had no side effects at all. I am surprised that again I can go a day without being hungry at all but of course, I force myself to eat something even with food I will eat but will be so full easily. I take protein shakes daily as my meal replacement. I'm taking fiber (gummies) so I can go to the bathroom with no problem and it helps a lot. Overall I am pretty happy with the result."

8 / 10
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  • Lorra...
  • Taken for less than 1 month
  • October 3, 2023

Wegovy (semaglutide) "I was prescribed Wegovy for weight loss purposes. I'm 5'11 and 225 pounds with a BMI of 31%, so I can be considered obese. I've been on it for one week and have lost 7 pounds. I'm starting with the lowest dosage (.25). First of all, the injection was completely painless (for me). I also inject Humira bi-weekly, so maybe I'm just used to it, but I was shocked to feel absolutely nothing. I questioned if I was doing it right because it was so painless. Do not let some testimonials scare you! I did a lot of research while waiting for the drug to come back into stock. 90% of what I read were complaints about vomiting, diarrhea, and some people getting so sick they had to stop taking it. Some of these reviews were written after only a week or two of using the drug. So far, my personal experience has been completely different from what I've read. That could change as I increase the dosage. As of right now, the only side effect I'm experiencing is a complete lack of appetite."

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Frequently asked questions

  • Kelly...
  • Taken for 1 to 6 months
  • May 4, 2023

Wegovy (semaglutide) "I have been on Wegovy for almost 7 weeks, and have lost over 22 lbs. From the moment I took the first injection the food noise was gone. At times it feels progress is slow, but in truth the progress has been steady. I have not started dieting or exercising, I am focusing on eating healthier and listening to my body for signs that I am full. I have heard of bad side effects, though I personally have not experienced any. Prior to this medication I have lost, gained and relost 50-100 lbs over and over again."

10 / 10
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  • Fingers...
  • Taken for 1 to 6 months
  • July 5, 2022

Wegovy (semaglutide) "57 yr old on this for 3 1/2 weeks. I'd like to tell you how much I lost (was 4 pounds at 3 weeks) but I am so constipated for 4 days I cannot be sure what my real weight is (it could be 6 pounds now). Get a telemedicine provider to send you a vial of semaglutide (not the pre loaded syringes) and use an insulin syringe to administer 1/2 the dose on one day with a ODT Zofran, then take the second half of the dose 24 hours later with another ODT Zofran. I administer in my outer thigh, like you would give insulin. The provider will tell you exactly how many "units" to administer per week, just cut it in half say Saturday and Sunday. Take a stool softener on Sunday, which I forgot to do this week! I have had zero gastrointestinal issues, no nausea, no vomiting. The Zofran may be causing some of the constipation and I don't consider this a real issue, just a minor side effect with an easy fix. I am a Nurse Practitioner, so I have been watching everything for real side effects. I'll update."

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Are you taking this medicine?

  • Erica
  • Taken for 1 to 6 months
  • March 29, 2023

Wegovy (semaglutide) "I've been on Wegovy for a little over a month now. My first injection of the .5mg dose was Friday (3/24/23). The weight loss has been fairly slow, but steady. The main thing that I've noticed is that it makes me feel full after I eat. I know it sounds strange, but for some reason, I've never felt hungry or full-- I ate when people told me and didn't stop eating until my plate was clean since I was a kid. Now, after I eat a bit, I feel full and stop eating. I've learned to be choosier with what I eat, opting for healthy things, protein and fiber, and less fat, and carbs. No crazy fad diets or anything, just being more mindful. My injections are Fridays, and I've noticed that Sundays are the worst days, but after 2 weeks on a dose, the side effects are pretty minimal. Just started the .5mg dose and so this past Sunday was bad, but my doctor gave me a PRN script for Zofran to help with nausea. I hope this review helps someone."

8 / 10
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  • LADw
  • Taken for 1 to 6 months
  • July 4, 2022

Wegovy (semaglutide) "I took Wegovy for a few month and did in fact lose some weight. The side effect are terrible as so many others have noted here. One thing that they don’t tell you is that the drug slows down the stomach ability to empty. This is why people feel full and experience reflux, nausea, etc. In my case the drug not only slowed down my stomach ability to empty it permanently paralyzed my stomach muscles, a condition called gastroparesis. The only remedy was to have a neurotransmitter implanted in my stomach which forces the muscles to move. Do NOT take or first this medication. You could end up like me with a lifetime medical issue. No weight loss is worth that."

1 / 10
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More FAQ

  • kathyc
  • Taken for 6 months to 1 year
  • April 26, 2024

Wegovy (semaglutide) "I have been on Wegovy for about 8 months. My weight has dropped about 40 lbs. In the beginning, I did have upset stomach on occasion and found there are a few things I could not eat or drink anymore, but my blood pressure is a lot better. I feel good about myself. I don't need to lose any more weight. I am walking a mile a day, using my weights every morning, and I don't drink much alcohol anymore, not that I am saying I was an over drinker, but because of the calories and some of it doesn't taste good anymore. It has helped me eat better, rethink about how much I eat, and be healthier. My old clothes that didn't fit are now fitting, and I have a whole new wardrobe to go through."

10 / 10
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  • Mike
  • Taken for 1 to 6 months
  • March 21, 2022

Wegovy (semaglutide) "Drug has been life changing. When I began I was 6'3" 357 lbs. Today is exactly 4 months in and I'm down 60 lbs exactly. Blood pressure meds cut in half, discontinued lasix and potassium pills. Currently taking 2.4 mg / weekly. My side effects have been relatively non existent. Early on some gastro upset and heartburn but all went away with time."

10 / 10
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  • Me22
  • Taken for 1 to 6 months
  • March 31, 2022

Wegovy (semaglutide) "Just finished the last shot of 2.4 mg pack. I’ve lost 27 pounds and literally do not think about food. No cravings, and I eat normally (albeit smaller amounts). Some side effects at the beginning but nothing terrible and they all eventually stopped. If you can afford it - this is a life changer."

10 / 10
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  • Stalled
  • Taken for 1 to 2 years
  • February 15, 2024

Wegovy (semaglutide) "It has been a year since I have been on Wegovy. I went up to 2.4 by August 1, 2023, and had lost 50 pounds in those six months. The last 6 months, I have not lost any weight. I have not gained but definitely stalled for 6 months. I just went down to 1.7 last week to see if the high dose 2.4 is the reason for the stall. Appetite suppression also stopped at 8 months. No clue what to do, but I will stay on 1.7 for a month to see if it changes the stall. Good luck everyone! I have a whole new life after losing 50 pounds! Life is good!"

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  • ShellB
  • Taken for 6 months to 1 year
  • May 1, 2022

Wegovy (semaglutide) "I began Wegovy in late August '21. I had bariatric surgery (2000). Menopause, major life changes & COVID resulted in a 60 lb wgt gain over 5 years. It's May 1 & I've lost a total of 81 lbs. My BMI has gone from 38 to 25 & I never got to the 2.4 injection. I had slight nausea & 2 incidents of gastronomic uncertainty ("Sharts") the 1st 2 weeks, but nothing after that. I walked 1.5 - 2.0 miles 6 or 7 days weekly, ate a high protein, low carb diet, switched to 50/50 Stevia/Sugar as a sweetener & ceased eating after 8pm nightly. I feel great & because of my weight loss I can delay my other hip replacement. Wegovy gave me a 2nd chance at better health & I'll continue to use it for maintenance."

10 / 10
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  • jmm
  • September 27, 2022

Wegovy (semaglutide) "For me it is a miracle drug! I have had no side effects and have been on it since December of 2021. I was doing other medications, that helped a little, but I was stuck teetering between 190-195 could not pass that. As soon as I started Wegovy the weight started to come off. I am now right around 160 and I am close to my goal. I am also 60 which makes weight loss even more difficult. I highly recommend this treatment!"

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  • MRS
  • Taken for 1 to 6 months
  • January 10, 2022

Wegovy (semaglutide) "I have been taking Wegovy since August 2021. I am down 45 pounds. I did low carb with this which has really helped me to lose the weight I have wanted to lose. The side effects are very real, extreme constipation and nausea for two days after injection. The doctor prescribed zofran for the nausea and I have taken stool softener for the constipation. All things said it really helped curb my appetite. But you have to diet with it."

9 / 10
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  • Highly...
  • Taken for 1 to 6 months
  • April 18, 2023

Wegovy (semaglutide) "I was worried about side effects with this medication but I have not had any. So far I have lost 16 lbs in two and a half months, with diet and exercise. I started with the .25 mg dose, and I am now on the 1 mg dose. I would recommend it to others that want to try it"

10 / 10
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  • ShyFox
  • Taken for 1 to 6 months
  • November 1, 2021

Wegovy (semaglutide) "Been on Wegovy for 7 weeks. Lost 14 pounds. 2nd week into .50mg. It’s a little rough on my stomach. Taking prescription for nausea which happens the day of the injection. Feel tired and occasionally get severe abdominal pains. I can’t eat much and have to really watch the types of food. No greasy foods or spicy or heavy. The intestinal pains were very severe after eating wrong foods. I’m happy with the weight loss but the side effects are rough."

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  • Big...
  • Taken for 1 to 6 months
  • April 24, 2023

Wegovy (semaglutide) "I have been on Wegovy for over a month now, it has been a life changer for me. Very few side effects. I have way more energy, I can fit into clothes that were so tight I couldn't wear them, and I have fewer aches and pains. My mindset is so different. I am 5 11', started at 263 lbs. (Obese) I have lost almost 15 lbs. This stuff pretty much keeps those hunger cravings away. I have changed my eating habits as well, I only eat fruits, veggies, and salads, I do plan on going back to some of my other favs' but for now, I'm sticking to no pasta, pizza, bread, or desserts. I only eat between the hours of 6 am to 3 pm. I have been walking around a 1/2 mile per day on my lunch breaks. I do not eat much, seems like I get full very quickly. Another benefit, I have bitten my nails my entire life, since starting Wegovy, I have not touched them, it's quite unbelievable."

10 / 10
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  • TBH
  • Taken for less than 1 month
  • February 25, 2023

Wegovy (semaglutide) "Started 2/23/23. 0.25. 64 years old, H 5/6, W 217. Only side effect is dizziness when standing up and subsides with a minute or two. That seems to be hypoglycemia. As of today 2/26/23 it has definitely curbed my appetite. I will check back in a month to let you know my progress."

8 / 10
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  • usmc
  • Taken for 1 to 6 months
  • November 29, 2022

Wegovy (semaglutide) "At this time, I’m on my 5th week of the maintenance dose. The only side effect I’ve had is occasional constipation, but as a 25-year medical professional, I know how to deal with it medically and in conjunction with my VA doctor and pharmacist. At times, I would get hypoglycemic, but again I knew how to combat that. At this dose I find myself somewhat more fatigued but I can deal with that. Cat naps usually do the trick. I started at 393 and 6’3”. I’m 56 years old. I’m down to 349 since I started, which for me is great. I have critical low testosterone and can’t take testosterone due to my history of pulmonary embolisms. So I don’t mind losing only 2 pounds a week. I can now walk so much better and farther. I’m 95% VA disability rated, and I’ll tell you, I feel and look so much better after starting to use Wegovy. The VA truly cares for us veterans no matter what you hear. Stay blessed and hang in there."

10 / 10
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  • WagOn
  • Taken for less than 1 month
  • April 5, 2023

Wegovy (semaglutide) "I took my first shot of .25 5 days ago. I was extremely nervous about taking it due to all of the negative side effects that I read others have had. I decided to inject in my upper thigh late on a Friday afternoon, so that if I did feel sick I had the weekend to take it easy and deal with it. The injection was painless and very easy to administer myself. I honestly noticed no side effects after taking it, other than not thinking about food as much and wanting to eat a little less. I did push the boundaries on the third evening after taking it and I did have bad nausea (I actually vomited) and felt generally ill for about 16 hours (not bad enough to not work though). I pushed the boundaries by over eating air fried chicken wings (no sauce) that were a bit more greasy/oily than normal. Those really set me off and I realized that I: 1. can no longer eat any type of greasy food and 2. cannot eat too much. As long as I stick to my normal healthy, low carb diet, I feel just fine (so far)."

9 / 10
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  • Tough...
  • Taken for less than 1 month
  • March 14, 2023

Wegovy (semaglutide) "I am on my 3rd 0.25 dose of Wegovy. I feel terrible most of the time. I have lost 5 lbs and am definitely not hungry due to nausea. My prescriber will not prescribe Zofran with Wegovy, because she feels nausea that severe should be considered a negative side-effect and the medication stopped. That's reasonable. I read the reviews before I began the med and take Omeprazole daily, as well as MirraLax. I am 57, menopausal and used to feel really good most of the time. Sadly, this med is not worth the side effects for me. I really, really wanted to tough it out but as a nurse, I feel it's creating problems that I did not have before taking this medication. The nausea is constant, the belching/burping is so frequent that its embarrassing, stools are like a rock, and the worst feeling of chest tightness. I had so hoped I would be one of those without adverse side effects but I am not."

3 / 10
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  • Never...
  • Taken for 1 to 6 months
  • June 10, 2023

Wegovy (semaglutide) "Let me first say that digestively, I have never been more miserable in my life than I was on this "medication." Wegovy gave me abdominal cramps so bad I had to go to the ER. I was very dehydrated and in so much pain. Luckily my CT was normal, but my WBC was elevated. Maybe this is some other side effect that will start being reported more often now that half the population seems to be taking it. I started at 0.25 mg and did that weekly for 4 weeks. During that time, I was ok but constantly felt somewhat bloated and would burp way more than what would be considered normal. I am glad some people had success with this but for me, my life was better before this medication. I'll take being "overweight" and feeling great to this any day. I just hope there is no permanent damage. Thanks for the misery, Wegovy. Never again. Big pharma can take their bogus, fabricated BMI and stick it. They want people to be miserable and addicted to whatever drug they cook up for their investors."

1 / 10
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  • Dotzer
  • Taken for less than 1 month
  • April 5, 2023

Ozempic (semaglutide) "I'm a 38-year-old man with type 2 diabetes and overweight. I was on metformin for three years and followed a good diet and exercise regime, but I couldn't lose weight. Although my blood sugars were perfect on metformin, weight was my issue. My doctor prescribed me Ozempic 0.25 mg, and I was very worried about the side effects. However, I started it recently anyway and injected it in the upper thigh once weekly. I had no issues other than constipation, which I overcame with laxatives and increased water intake. My appetite was reduced by 90%. I used to overeat, but now I can only manage two small meals a day. It's really working so far, but it's still early days. I'm in Ireland, and it costs €150 a month for four injections, which are covered by my medical card. I'll provide an updated review in three months to report how it has helped me lose weight on the scales."

9 / 10
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  • Kira
  • Taken for 1 to 6 months
  • February 3, 2022

Wegovy (semaglutide) "I'm on 2.4 now. Started yesterday and still have pretty bad nausea. It's the worst it's been. Before, it was quite negligible or non-existent. So far, I've lost 21 lbs in 4 months. I was 216, now 195 and I am 5'4". I still have a long way to go. I started working out and started a vegan diet in January to improve my cholesterol. I know it's tough. I have read so much about it and my expectations were high, like all I need to do is take this injection and the weight will fall off! This will fix all of my problems! I'll find true happiness! But...that's not the case for most people, including me. My provider said that some of her patients have seen no results. She said a 20 lb weight loss is right on track for me and more sustainable than the amazing results some are seeing (though everyone is different). Remember: we are more than our weight. And there is no one answer. If you are taking this and it's not working, it's not you."

8 / 10
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  • MsJ
  • Taken for 1 to 6 months
  • November 5, 2023

Wegovy (semaglutide) "In August, my doctor prescribed me Wegovy 0.25. It was out of stock, so I started with Saxenda. I took it for 1 month and lost 13 lbs. When it was time to refill, Saxenda was out of stock, so my doctor switched me to Wegovy 1.7. Since I didn’t have any side effects and that is what was available. Since 8/9/23, when I started my weight loss journey, I have now lost a total of 40 lbs. The medication does work. The only problem is it staying in stock. I can now fit into clothes I wore pre-pandemic. My BMI went from 36 to now 28.7. The only side effect is some stomach cramping, but I realized I needed to drink more water and force myself to eat something even though I am not hungry. Hope this is helpful."

9 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.