Semaglutide for Weight Loss (Obesity/Overweight) User Reviews (Page 2)
Brand names: Ozempic, Rybelsus, Wegovy
Reviews for Semaglutide
- Lif...
- Taken for 1 to 6 months
- May 10, 2023
"So far, after 4 months, this has helped boost weight loss. At 57, I’ve been battling with the slowest metabolism on earth! It didn’t matter what I ate, when, how, how much, nothing. I started an exercise program that I promised myself I would stick with for a minimum of 2 months and I did it like an adult. Meaning I didn't work out for 3 hours my first time. After 4 months, I’ve lost 50 lbs, again, I added exercise prior to starting Wegovy because I had both knees replaced. I will have nothing else replaced due to being overweight. I, personally, have had NO side effects except I’m not hungry at all. But this allows me to make better choices. Best of luck to all!"
- Anonymous
- Taken for less than 1 month
- January 22, 2022
"Worst experience of my life. After the second 0.25 dose, I was up all night vomiting and diarrhea. The next day, I had chest pain, shaking, brain fog, stomach pain, more diarrhea, and had to go to the ER. After they gave me Benadryl and morphine, I started to feel better. Still have burping, gas, and acid reflux terribly. WILL NEVER TRY THIS AGAIN! It is not worth it to me! Wish it would hurry up and get out of my system."
Frequently asked questions
- Ozempic Side Effects to Watch For
- Wegovy vs Ozempic: Which is Right for You?
- Tirzepatide vs semaglutide: How do they compare?
- Why am I not losing weight on Ozempic?
- Mim...
- Taken for 1 to 6 months
- July 7, 2023
"Since my first injection, I have felt utterly dreadful. The nausea is one thing, but I have constant fatigue that prevents me from leading my normal life. I know it suppresses appetite, but I don’t have ANY appetite at all and cannot face food. I know if I eat, I will feel a bit better, but it’s impossible. I actually feel like I’ve been drugged. Yes, the ‘food noise’ has gone, and I no longer overeat or binge, but I feel like everything is suppressed - like I’m on a strong drug. I did 4 weeks at 0.25 and have just done one week at 0.5, but I can’t do this anymore. I feel utterly dreadful. I am so pleased it’s helping so many people, but more research is needed into why some people just can’t tolerate it."
- Bo ...
- Taken for 6 months to 1 year
- February 28, 2022
"I started with Ozempic (which is the same thing, I think) for assistance with diabetes. In the first year, I lost fifty pounds, I became more capable of moving better, and I started. In February and March of the second year, I was hospitalized twice for massive blood clots in my right thigh and the Wegovy was put aside for a couple of months. In April of 2021, my endocrinologist asked me if I would like to switch to this new version that might give me a boost. Sure, why not. I started with the lowest and immediately moved to the 2.4 doses. I have had no side effects no problems with the injection sites. The only issue has been obtaining the medicine. Oh, health changes. Within the first year of the Ozempic, my A1c went from 8.1 to 7.3, in the second year it has dropped to 6.1. My blood glucose averages are about 130, I can live with that! I have to be careful with going too low! Total weight loss is hovering between 95 and 100 lbs."
Are you taking this medicine?
Your review helps others make informed decisions.- Bmi...
- Taken for 1 to 6 months
- December 28, 2021
"I feel completely normal with regard to appetite. I hardly think of food and never finish my plate. I definitely needed the Zofran script - I found the first two days were the most difficult. Definitely losing weight, which makes it easier to do gentle stretching to prepare for more walking and stairs. Fear is alleviated…hope is restored…I have control, therefore, the ability to make healthier food choices and increase exercise. Not for everyone, definitely for me."
- Sks...
- Taken for less than 1 month
- May 25, 2023
"I never leave reviews and rarely have side effects from medication. However, after one injection on the lowest dose, I am so beyond sick. Two days after my injection, I got a migraine followed by extreme vomiting for 4 days, chills, nausea, and a trip to the ER. This medication made me so unbelievably sick, it is like I've been poisoned. I have missed 4 days of work and am so weak. Living on Pedialyte and numerous nausea medications. Please be so careful. I was so hopeful and had no idea this would happen to me."
More FAQ
- Does Ozempic cause muscle loss and how to prevent it?
- How much does semaglutide cost?
- How does semaglutide work for weight loss?
- Where and how should Ozempic be injected?
- Ama...
- Taken for 1 to 6 months
- April 15, 2023
"I never had any weight issues until I turned 60. All the weight gain seemed to go right to my stomach. No matter what I did (including exercise and diet), nothing worked to diminish the belly fat. I started taking Ozempic at 0.25mg/week for 4 injections. I lost 15 pounds on that starter dosage. I increased to 0.5mg the following month and lost another 15 pounds. I will begin the 1mg dose this weekend for the next month. The Ozempic seemed to target that subcutaneous belly fat, which is where I had the greatest weight loss. Except for a mild headache after the first dose and subsequent constipation, there were no other side effects. I took something to relieve constipation. My stomach is now almost as flat as a board, and I don’t look pregnant. I know carrying all that excess subcutaneous fat is very dangerous, and Ozempic melted that fat away. I would recommend keeping yourself very well hydrated and asking your doctor for a prescription to address the constipation. Truly amazing!"
- RNi...
- Taken for 1 to 6 months
- May 4, 2022
"Wegovy does work, problem is... I feel like dirt all day long. I'm fatigued, nauseous, and even the smell of food makes me vomit. My heart races, and I'm quite dizzy. I lost 55 lbs. Do I look good? Yes. Do I feel good? No. I'm down to 153 lbs now. It's time to stop this medication."
- Jed...
- Taken for 1 to 6 months
- December 15, 2021
"Halfway through the 1.7mg dose. Been on for about 4.5 months. Have lost a total of 35 pounds. My weight loss has slowed down since on the 1.7 dose. Still losing but not as quickly as in the beginning. Have no real interest in food anymore. Sometimes have to eat when not hungry due to low blood sugar (had this prior to Wegovy use). Been trying to lose weight for months. Wegovy is the only thing to work for my obesity due to medical issues. Have noticed off and on fatigue, dizziness, constipation, stomach pain, gas, belching, and hair loss. Can no longer eat fried, greasy food without feeling sick, which is good. Now I want healthy food instead."
- Anonymous
- Taken for less than 1 month
- February 24, 2023
"Horrible experience. I only took 2 dosages because I had difficulty functioning with headaches, eye pain, nausea, dizziness, and overall feeling awful. The additional issue is I've been off the drug for a week and can't get rid of the symptoms. I'm nauseous every day, with headaches, and dizziness. How long until all of this goes away?"
- sou...
- Taken for 1 to 6 months
- March 23, 2023
"I am in my sixth week of Wegovy (4 weeks at 0.25 and now 2 at 0.5). I am a male in my early 50s, 5'9'' with a lot of weight to lose — about 120 pounds. In the first month, I experienced no side effects apart from reduced appetite and lost 10 pounds. I had just begun dieting when I started — nothing extreme, just eliminating the worst offenders: sugar, not eating after 6pm, and portion control. I have already lost 6 pounds this month. I have experienced some mild nausea this month on the 0.5 dose, nothing close to vomiting but definitely present, especially the two days after injection. Haven't had negative reactions to specific types of food like others have had until yesterday. Had some Korean BBQ and was burping garlic all night with some intestinal discomfort - so I guess that's a no go. I am considering holding at this dose before going up again. As long as the weight loss is happening at this rate, I am not keen to risk greater side effects."
- Anonymous
- Taken for less than 1 month
- September 5, 2023
"First, I wanted to say... I was TERRIFIED to start Wegovy because of all the negative reviews about side effects, but I convinced myself to focus on the positive reviews which outweighed the negative ones. I started Wegovy 3 weeks ago at 0.25 mg. I will be taking my 4th dose of 0.25 mg this week. I usually take it on Fridays around 9:30 pm so I can sleep off any side effects and then relax on the weekend. So far, I have experienced mild side effects on the second day after the first and second shot - nausea, light headache, a little dizziness, and dry mouth that lasted for maybe 1 to 2 hours. Side effects were manageable with Motrin/Tylenol and Pepto Bismol. I haven't had any major side effects. I weighed 210 when I started, and I weighed 199.5 this morning, so that's almost 11 pounds down in 3 weeks. I am happy I decided to not let the negative reviews discourage me from trying Wegovy. All I wanted to see was a weight under 200 pounds! I will start 0.5 mg in 2 weeks - will update again."
- Jer...
- Taken for 1 to 6 months
- May 10, 2023
"I am finishing my 8th week on Wegovy. I have lost 17.1 pounds and feel amazing. I was afraid to start because of the side effects, but so far, I have been lucky and haven't had them. The best thing about Wegovy is the fact that my mind is no longer full of obsessive thoughts about food. I have lost weight a million times, but this is the first time I am aware that I am NOT thinking about food all the time. I eat really reasonable portions of food and am satisfied. No desire for extra food or snacks. It is absolutely a miracle."
- Jac...
- Taken for less than 1 month
- March 12, 2023
"Worst medication ever. On the lowest dose, I became deathly ill. I couldn't stop vomiting for a week. I could not walk because of extreme dizziness, and I could barely see from blurry vision. It also gave me the worst migraine of my life and suicidal thoughts and depression. I only lost weight because I could not eat at all and couldn't keep liquids down, so I was severely dehydrated. The side effects and long-term effects are so severe that the minor weight loss you would have from this medication is not worth it."
- KCl...
- Taken for 1 to 6 months
- April 19, 2023
"I have been taking Ozempic since 12/22. I was put on this injectable drug due to obesity, high cholesterol, and borderline high blood pressure plus pre-diabetic. I have lost 30 lbs. so far. I am more than pleased that my cholesterol is now 180 from 270 on medication. I have never been below 200 total cholesterol in my life! I have had no symptoms taking Ozempic except a little indigestion the first month. It is very convenient to use (inject once a week), and the needle is so thin (less than a hair) you don’t even feel it. I had tried every diet, exercise, and fasting to lose weight and get my cholesterol under control. Ozempic is the only thing that has worked."
- fin...
- Taken for 1 to 6 months
- January 17, 2022
"Took it for 8 weeks, made it through the 2nd titrated dose and couldn't handle it anymore. Nausea, gas, bloat, constipation, diarrhea, and it was worse at night while lying down. Never improved, but actually got worse by week 8. Not sure how anyone makes it to the full dose. Also did not drop a single pound. There were days I only consumed 600 calories and still felt awful. I read another review very similar and agree that you absolutely cannot eat anything spicy. Bland food days were better but there are not enough antacids and constipation meds in the world to make me want to lose 20 pounds this badly. Took my last dose 10 days ago and am still dealing with residual GI upset. Hope physicians are more forthcoming about the side effects and do not tell patients they happen but subside in a couple of days - they do not."
- Mic...
- Taken for 1 to 2 years
- May 2, 2024
"I started Wegovy on 1/31/2023 at 224 lbs. As of today, 5/2/2024, I am at 154 lbs. I have had minimal side effects. I do not have cravings and no longer do I think about what I am going to eat next. I work out 3-4 days a week but did that prior to starting Wegovy. On 0.25, I lost 6 lbs. On 0.5, I lost 3 lbs. In the first 4 weeks of 1.0, I lost 6 lbs. In the second 4 weeks, I lost 3 lbs. In my first 4 weeks of 1.7, I lost 7 lbs and in my second 4 weeks, I lost 2 lbs. I started 2.4 on 7/17/2023, and on that, I have lost 39 lbs. Some weeks the weight loss was larger than others, but there was always weight loss. I have no complaints and would recommend anyone to speak to their doctor if they are interested. We are all different, and for some people, it works and for some, it does not. Some people have terrible side effects, and some don't."
- She...
- Taken for 6 months to 1 year
- May 1, 2022
"I began Wegovy in late August '21. I had bariatric surgery in 2000. Menopause, major life changes, and COVID resulted in a 60 lb weight gain over 5 years. It's May 1, and I've lost a total of 81 lbs. My BMI has gone from 38 to 25, and I never got to the 2.4 injection. I had slight nausea and 2 incidents of gastrointestinal uncertainty ('sharts') the first 2 weeks, but nothing after that. I walked 1.5 - 2.0 miles 6 or 7 days weekly, ate a high-protein, low-carb diet, switched to 50/50 Stevia/Sugar as a sweetener, and ceased eating after 8 pm nightly. I feel great, and because of my weight loss, I can delay my other hip replacement. Wegovy gave me a second chance at better health, and I'll continue to use it for maintenance."
- LAD...
- Taken for 1 to 6 months
- July 4, 2022
"I took Wegovy for a few months and did, in fact, lose some weight. The side effects are terrible, as so many others have noted here. One thing that they don’t tell you is that the drug slows down the stomach's ability to empty. This is why people feel full and experience reflux, nausea, etc. In my case, the drug not only slowed down my stomach's ability to empty, it permanently paralyzed my stomach muscles, a condition called gastroparesis. The only remedy was to have a neurotransmitter implanted in my stomach, which forces the muscles to move. Do NOT take or first this medication. You could end up like me with a lifetime medical issue. No weight loss is worth that."
- Slw...
- Taken for 1 to 6 months
- February 11, 2022
"I'm on my 13th week at 1mg now. I love it. Yes, I was nauseated at first, but the quick weight loss results made me want to continue. At this dosage, I am not really hungry for food, and if I do feel hungry, it doesn't take much food for me to feel satisfied. I have really cut my portions and also use high fiber, high protein foods. Constipation is real, people, laxatives help. I make good food choices now and am down 25 lbs. I want to keep going, but the coupon has run out, and now my out-of-pocket cost with insurance is around $900. I am so disappointed to have to stop and worried about gaining back or not losing anymore. Novo really needs to make this affordable. The price is ridiculous, and millions of people are dying from comorbidities to obesity every day. I have high-end insurance, and still cannot afford the copays."
- MRS...
- Taken for 1 to 6 months
- January 10, 2022
"I have been taking Wegovy since August 2021. I am down 45 pounds. I did low carb with this which has really helped me to lose the weight I have wanted to lose. The side effects are very real, extreme constipation and nausea for two days after injection. The doctor prescribed Zofran for the nausea and I have taken a stool softener for the constipation. All things said, it really helped curb my appetite. But you have to diet with it."
- Me2...
- Taken for 1 to 6 months
- March 31, 2022
"Just finished the last shot of 2.4 mg pack. I’ve lost 27 pounds and literally do not think about food. No cravings, and I eat normally (albeit smaller amounts). Some side effects at the beginning but nothing terrible and they all eventually stopped. If you can afford it - this is a life changer."
- Mik...
- Taken for 1 to 6 months
- March 21, 2022
"Drug has been life-changing. When I began, I was 6'3'' and 357 lbs. Today is exactly 4 months in, and I'm down 60 lbs exactly. Blood pressure meds cut in half, discontinued Lasix and potassium pills. Currently taking 2.4 mg/weekly. My side effects have been relatively non-existent. Early on, some gastro upset and heartburn, but all went away with time."
- Weg...
- Taken for 1 to 6 months
- September 7, 2023
"Please do not let these reviews scare you like I almost did. I held off multiple weeks because of all these death-like reviews. Finally, when I did decide to just start—I hunkered down like the outside world was about to end. Did the world end? No. I was perfectly fine. Were there the occasional burp and heartburn? Yes. But nothing that wasn’t manageable. I’m over 14 weeks in now, and I barely have a side effect at all. My point—everyone’s body is different. Try it for yourself."
See also:
Mounjaro
Mounjaro is used for type 2 diabetes to help lower blood sugar levels. Mounjaro has also been shown ...
Rybelsus
Rybelsus tablets are used to improve blood sugar control in adults with type 2 diabetes, and may ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Zepbound
Zepbound (tirzepatide) is an FDA-approved weekly injection for weight loss and obstructive sleep ...
Wegovy
Wegovy (semaglutide) an FDA-approved weekly injection for weight loss and to reduce heart risks ...
Victoza
Victoza helps control blood sugar levels and reduce the risk of serious heart problems in people ...
Saxenda
Saxenda (liraglutide) injection is used for weight loss in obese or overweight patients. Includes ...
Alli
alli blocks the absorption of some of the fat that you eat and is used to treat obesity. Learn ...
Amphetamine
Amphetamine is a stimulant and is used to trat narcolepsy and attention deficit disorder. Includes ...
Tirzepatide
Tirzepatide is a once-weekly injection used for weight loss, sleep apnea, and type 2 diabetes ...
Are you taking this medicine?
Your review helps others make informed decisions.Learn more about Weight Loss
- Can You Mix Weight Loss Drugs and Alcohol?
- FDA-Approved Weight Loss Drugs: Can They Help You?
- Side Effects of Weight Loss Drugs
- Top 10 Diabetes Treatments You May Have Missed
- Weight Loss Drugs & Injections: What Are Your Options?
- Which Drugs Cause Weight Gain?
Care guides
More about semaglutide
- Check interactions
- Compare alternatives
- Reviews (2,704)
- Latest FDA alerts (5)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: GLP-1 Agonists (Incretin Mimetics)
- Breastfeeding
"I started Wegovy at the end of July 2021. I was up to the second dose amount. I stopped it on October 8, 2021, because I was experiencing extreme hair loss. I had called and spoken to a Wegovy representative the month before about it, and they said someone was going to call me, as this was not a side effect that they knew of. No one ever called. I did look on another site, and it did show hair loss. Knowing that hair loss with this product is real. It has been a very depressing time for me as the way I look at myself has changed because of the loss of my hair. HAIR LOSS IS REAL WITH WEGOVY"