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Quetiapine User Reviews & Ratings (Page 5)

Brand names: Seroquel, Seroquel XR

Quetiapine has an average rating of 7.3 out of 10 from a total of 2,136 reviews on Drugs.com. 64% of reviewers reported a positive experience, while 18% reported a negative experience.

Reviews for Quetiapine

  • Anonymous
  • February 2, 2012

Seroquel XR (quetiapine) for Depression "I've had depression since I was a young teenager. I didn't decide to get treatment until I was 24. I felt like I was unraveling. I didn't want to get out of bed. I lost interest in all the things that I once loved to do. I had problems with drugs and alcohol. Sleeping problems. The whole nine yards. The medication that my doctor decided to put me on was Seroquel XR. I was a little apprehensive at first, being a drug user for many years, I knew what Seroquel was. My doctor assured me that in a controlled and carefully watched environment, she believed it would help. She started me on 50 mgs. I've moved to 150 mgs. I've had drastic positive changes in my mood. I feel happy, rested, and content. No negative side effects. It worked miracles."

10 / 10
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  • KC85
  • Taken for 6 months to 1 year
  • August 17, 2023

Seroquel (quetiapine) for Bipolar Disorder "I was afraid to go on Seroquel because of the weight gain aspect that I heard complaints about. I have been on it for several months now and have not gained much. I am sleeping better than ever. It is a little tough to get out of bed in the morning, but once I get up, I am fine. The best thing about this medicine is how calm I feel on it. My anxiety is pretty much nonexistent at this point. I have BP1 with psychotic features, and I have not had any episodes at all since starting it. I would recommend this to anyone who needs help with stability with their bipolar and anxiety."

10 / 10
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  • lee...
  • Taken for 1 to 2 years
  • November 5, 2016

For Generalized Anxiety Disorder "2 years ago I had anxiety so bad that I would go 4-5 days without eating. I had awful intrusive thoughts and was almost in a constant state of panic. I could not sleep and had issues with early awakening. By the end of it, I had suicidal ideations. My doctor first tried Seroquel XR. This did not work for me and had me in a constant state of fog and exhaustion. Then she switched me to Seroquel 200mg at night. After 1 year of being on Seroquel, I sleep well every night. I no longer have issues with generalized anxiety and feel like a completely different person. Nothing bothers me and I am back to being happy-go-lucky. Yes, I have increased appetite but I walk every day and do yoga three times a week, so I have not gained any weight whatsoever."

9 / 10
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Frequently asked questions

  • Frank
  • February 8, 2020

For Insomnia "I am prescribed a 50 mg dose of Seroquel at night about 45 min before bed for sleep. It also stops my restless leg syndrome! Not what it is usually prescribed for, but it does the trick. I have been using it for 3 years with no side effects."

10 / 10
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81 Report
  • Cutie...
  • Taken for 1 to 6 months
  • April 23, 2020

Seroquel (quetiapine) for Schizophrenia "My son has autism and anxiety. He started experiencing psychosis/auditory hallucinations at age 18...so bad he would yell and get very angry. We have started Seroquel, been on it for over 2 months now, some improvement but not great. His doc has now upped it from 25mg to 500 mg. Along with Mirtazapine and Ativan for sleep. Hoping we can stay ahead of his episodes instead of chasing them. I'll give an update. Super helpful to read others' reviews. Praying we see some good results."

7 / 10
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Are you taking this medicine?

  • Mrque...
  • Taken for 6 months to 1 year
  • February 17, 2021

For Depression "Caution! Many reports here are from sub <100 mg dosages! These doses are not approved for depression. 150-300 mg have been studied in multiple trials with positive results. So if you want to take reports here seriously, at least look for those reports that actually report dosages clinically approved for depression! On a side note, I have used quetiapine for 8 months, and overall it's been a very good medication for me. The positives: not only is it anti-depressive for me, but it also alleviates my mood over my 'normal' not-depressant mood. It works very well for social anxiety for me (although on average this has not been seen in trials). Negative: it makes me tired the first 3 hours of the day, which is not trivial. (English is my second language; I rarely write it, so the spelling is probably not great.)"

8 / 10
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  • TCano
  • Taken for 6 months to 1 year
  • May 19, 2020

For Insomnia "I feel like taking Seroquel must be like getting roofied. I took the 100 mg, and it literally knocked me out for 12 hours straight. Then, after waking up, you're groggy for at least another 6 hours and are grumpy to the people around you. I also got restless leg syndrome or some kind of very weird involuntary leg movements. I would also always wake up in some kind of pain, and it might be due to the fact that you're so knocked out you're contorting your body in unusual positions while you sleep. I then got reduced halfway to the 50 mg, which did the same thing but with half of the same effects! Seroquel seems like a dangerous drug to me, and I've been on a few."

1 / 10
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  • miche...
  • Taken for 5 to 10 years
  • August 5, 2014

For Insomnia "I had severe depression and could not sleep at all. My husband can testify that I could be awake for 4 days in a row. I had anxiety attacks. I was on Cymbalta, Lamotrigine, and Molipaxin. But the depression stayed, and my sleep did not improve at all. I was hospitalized 3 times in less than 3 years. The last time I was gradually put on bigger doses of Seroquel - up to 400mg. The last 2 days I slept through the whole night - deep sleep! I have been on it for more than 5 years. I take it at night - about an hour before I want to sleep. I have slept every night. My mood has been stable all these years - no depression, anxiety attacks, or weight gain. I do have difficulty getting 'fully awake' in the morning. But I would rather have this 'side effect'."

10 / 10
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  • kaykay
  • November 14, 2014

Seroquel (quetiapine) for Bipolar Disorder "I love Seroquel but not the XR type. Helps you to sleep well at night and wake up feeling great. Gives you major munchies at night and woke up with Reese's Pieces all over the bed. Does help with a lot on highs and lows. So for me it's worth a little weight gain. Overall this medicine has changed my life."

8 / 10
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  • Sharon
  • Taken for 1 to 2 years
  • July 19, 2019

For Insomnia "I've been taking 12.5 to 25 mg quite frequently for insomnia I've had for decades. It works like a charm. No weight gain, etc. I am groggy when I wake up, but coffee takes care of it. I hope it works this well the rest of my life."

10 / 10
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  • Travis
  • Taken for 1 to 6 months
  • February 19, 2020

Seroquel (quetiapine) for Bipolar Disorder "I have been on Seroquel off and on for three years. I have tried other meds for my bipolar disorder, but nothing has worked better for me. I feel the only drawback is waking up in the morning with a cloudy head and dry mouth."

9 / 10
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  • iluzz...
  • October 30, 2007

Seroquel (quetiapine) for Bipolar Disorder "After suffering all of my life with depression and then later in life (20-33) with severe anxiety, insomnia, and a general feeling of restlessness to the point I thought I was going to 'crawl the walls', I was prescribed Seroquel. I quickly found out I had to take my dose at bedtime due to being so sleepy when I took it during the day. Seroquel has been the ONLY medicine that has worked for me to ease the symptoms of my Bipolar Disorder 1. A Big Thanks to Seroquel for making life easier for me!"

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  • Zully
  • May 2, 2020

Seroquel (quetiapine) for Bipolar Disorder "I can now see my own signs of mania or depression (having had Dialectical Behavioral Therapy for six months). With that said, the meds are not miracles, and after some dialectical treatment to add to my “toolbox”, Seroquel really helps. When I am restless, having racing thoughts, and feeling moody, I feel well-balanced after about 48-72 hours of using coping skills and adding Seroquel to prevent lack of sleep, which can worsen thoughts, moods, eating, etc. For me, it’s very helpful to have self-relaxation skills to manage my reactions. I give this medication, after months of skill work, an A++. My experience is not to say it is 100% fluent to all bipolar sufferers. The good thing is that DBT is not a medication so it won’t hurt to try it as a “tool”. The side effects are mild. It does make me drowsy, and I sometimes get an oily face, yet I can accept that over extended episodes. I also have to keep drinking lots of water as dry mouth is mild and I do feel thirsty."

10 / 10
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  • Anonymous
  • September 28, 2019

For Generalized Anxiety Disorder "My doctor prescribed Quetiapine 50 mg for my anxiety. I took one before bedtime. Unfortunately, I couldn’t sleep, it felt like I was closing my eyes but couldn't shut down my brain. After 6 hours of very light and inconsistent sleep, I decided not to stay in bed and got up. Once I sat down, I started feeling my heart pounding very hard. I went to the restroom, and then the palpitations went from bad to worse. I had a severe panic attack that lasted for almost 45 minutes. It was a horrible experience for me!"

1 / 10
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  • mutley
  • Taken for 5 to 10 years
  • January 3, 2017

For Generalized Anxiety Disorder "I can honestly say that quetiapine has saved my life. I take between 25mg during the day and 50mg at night. Anxiety is a wearing experience, like a caterpillar gnawing away at your well-being in an endless cycle. I have been on it for about 7 years now, and I was prescribed it by a one-time visit to a psychiatrist at the surgery. The winter months with the dark nights here in the UK can be unremitting, but this little pill does so much and is not addictive. If you're in doubt, go for it... although all drugs work differently for everyone."

10 / 10
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  • lipel...
  • Taken for 2 to 5 years
  • September 12, 2020

Seroquel (quetiapine) for Schizoaffective Disorder "My experience with quetiapine is amazingly positive. I tried Invega (that was bad) with unsuccessful results. I take quetiapine at a dose of 50 mg at night, and it makes me so much more relaxed and without any bad feelings or thoughts. If you want to be healthy and active during your days, this drug is highly recommended. In my case, it is used at night before sleep. It works!"

10 / 10
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  • Pinkt...
  • Taken for 1 to 6 months
  • October 4, 2019

For Insomnia "My doctor put me on a low dose of quetiapine to help with sleep as I also have mood issues. Quetiapine works very well to help you sleep. Before I started taking it, it would take me probably 2 to 3 hours to fall asleep on my own, within a half hour of quetiapine I could sleep. This was great at first, however, now, if I don't take it I can't sleep AT ALL. If I don't take it, for whatever reason, no matter how tired I am, my body will not fall asleep. I have been up for more than 30 hours multiple times. I can lay in bed in complete silence and darkness for 12 hours and not fall asleep for a minute. My body is dependent and I don't like it at all. I just want to be able to even take a nap in the afternoon without taking something. If this is what the lowest dose can do, I can't imagine if I was on a higher dose."

8 / 10
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  • KKano
  • Taken for 10 years or more
  • September 27, 2019

For Insomnia "This specific medication has a bit of an angel/devil quality to it. In the previous posts, I see the possibility for some confused/misdiagnosed causes of insomnia. In bipolar people, regular prescription sleep aids don't really work because bipolar individuals can't sleep due to their brains having a hard time turning off or turning on very quickly. I took 600mg of Seroquel for years, and it worked well to control the associated symptoms as it is an atypical antipsychotic with a mood stabilizing quality (the ONLY med of its kind), but put me in a 'fog'. After coming off the high dose for 2 or 3 years and suffering from bad insomnia, I asked to go on a low dose of Seroquel to get some sleep. My psychiatrist gave me 50mg, and it's working well. It's gonna work for some people, and it'll be a nightmare for others. Make sure you're being prescribed this medication by a psychiatrist NOT a GP or any other doc that can't validate why they choose to give you an atypical antipsychotic for sleep. Best wishes."

8 / 10
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  • star
  • September 28, 2013

For Generalized Anxiety Disorder "This medication has significantly reduced my anxiety. I am currently on 50 mg and I am able to sleep longer without midnight interruptions. Before Seroquel, I took 10 mg of Abilify (bad lethargy and restlessness). Life doesn't seem so scary to me anymore."

7 / 10
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  • ariel...
  • April 15, 2016

For Generalized Anxiety Disorder "I found Seroquel to be the wonder drug for my anxiety problems (due to long-term drug use). I was prescribed it five years ago at 100 mg a day. That has decreased to 50 mg at night, but I have since made the decision that I am ready to decrease this further to 25 mg a day, then down to none, as I have been free from addiction for the past five years I have been taking Seroquel. In my mind though, I would never have gotten through the debilitating anxiety that followed without the help of Seroquel."

10 / 10
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  • Maggie
  • Taken for 1 to 6 months
  • January 18, 2020

For Depression "Seroquel has been life-changing for me. I struggled with insomnia for years. Currently diagnosed with bipolar type II, I was prescribed Lamotrigine and Seroquel. Seroquel has helped me tremendously. I’m sleeping better than I ever have, and I’ve actually lost weight with this medication because now that I’m sleeping, I actually have the energy to work out every day. I am so thankful for this medication!"

10 / 10
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  • DylanS
  • Taken for 1 to 2 years
  • June 29, 2012

Seroquel (quetiapine) for Post Traumatic Stress Disorder "300 mg 4x/day. I used to have horrible hyper-vigilance, hyper-startle, anxiety, paranoia, insomnia symptoms. NOTHING (meditation, yoga, EMDR, etc.) helped that much, let alone fix it. So, the doctor said to try this. Because of my side-effect sensitivity, my doctor started me on 25 mg. That first night, I slept a full night for the first time in months. But then I started sleeping too much - up to 14 hrs a day on the weekends. We backed off to 12.5 mg & my life CHANGED. I'm under more stress right now so my dose is back to 25 mg & I'm doing great on it. It pulls me down out of that watchfulness that prevents me from doing anything but surviving (and poorly, at that). For me, after a near-lifetime of struggle, this is a miracle."

10 / 10
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  • Elano
  • February 20, 2020

Seroquel (quetiapine) for Bipolar Disorder "I suffer from Bipolar II, take 200 mg Lamictal daily, and was prescribed 25 mg Seroquel to take at night to help me sleep during hypomanic episodes. My psychiatrist claimed it would calm the racing thoughts, help me fall asleep, and hopefully make me think more clearly during the day. After taking it, I would still be awake for a couple of hours trying to sleep and still having racing thoughts. In the morning, I had the worst experiences trying to wake up. I wasn’t trying to wake up early or anything, like 11 on my free days, so I could sleep in, and even then I could barely open my eyes enough to turn off my alarm and would immediately fall back asleep. After finally waking up, I felt groggy and disoriented throughout the day. I couldn’t think straight and was unable to focus during my classes. Not a good experience. I only took it a few times and decided it was only having negative effects, so I stopped taking it."

1 / 10
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  • luzma...
  • Taken for less than 1 month
  • March 15, 2021

For Obsessive Compulsive Disorder "This drug is the only drug I have ever taken that helps my massive anxiety and suicidal depression. I believe I am a high-functioning borderline, and I was spinning out of control after a traumatic breakup with my partner. This drug saved my life! It worked immediately, the first night I took it. It took away all my suicidal thoughts that were completely overwhelming me — likely saving me from a stay at a psychiatric hospital. It has also helped eradicate obsessive thoughts about my ex-partner and the compulsion to contact my partner. I feel calm and relatively reasonable. I’m an attorney, and I can now focus on work so much better! Before, I was simply overwhelmed and could not focus enough to comprehend documents and client comments/emails. I don’t know how this drug works, but what a godsend! I’m on 50mg nightly. I am so grateful!"

10 / 10
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  • Anonymous
  • May 26, 2011

Seroquel XR (quetiapine) for Depression "Seroquel XR has changed my life. I feel I am present again in my world. Before taking this medication, I had very little hope that I would ever feel enthusiastic about life. I recognize myself again. I can't say enough about how excited I am about living. I tried so many therapies and had given up hope anything would work. The combination of my antidepressant and Seroquel XR was the key for me."

10 / 10
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153 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.