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Promethazine for Nausea/Vomiting User Reviews (Page 3)

Brand names: Promethegan, Antinaus 50, Anergan 50, Adgan Phenadoz

Promethazine has an average rating of 8.3 out of 10 from a total of 164 reviews for the treatment of Nausea/Vomiting. 80% of reviewers reported a positive experience, while 12% reported a negative experience.

Reviews for Promethazine

  • Hoosier...
  • Taken for 1 to 6 months
  • May 2, 2016

"While in the hospital, I was suffering from nausea and vomiting. Since I could not keep anything down because of the vomiting, I was given Zofran via IV. It worked quickly and controlled my nausea and vomiting. I was given a prescription for Zofran when I was discharged. When the vomiting began again at home, I was unable to hold down the Zofran long enough for it to work. My doctor called in a script for Phenergan (promethazine) rectal suppositories. I found that they worked almost as quickly as the IV Zofran and actually did a better job controlling the nausea and vomiting. As mentioned in other reviews, both the pills and suppositories can make you a bit sleepy."

9 / 10
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  • resho...
  • September 19, 2008

Phenergan (promethazine) "Phenergan has been a life saver. I am a little over 5 months pregnant and have not been able to enjoy a meal for at least the last 3-4 months. I went to the doctor and she tried me on phenergan and it has truly been a blessing. I can eat and not be scared that I'll vomit. It does make me a sleepy if I take the entire pill, but if I just take half I can eat at work, during the day. At home I take the whole thing and sleep like a baby. My only negative is there is really no information about how it affects an unborn child. A couple of my friends have taken it and they have healthy happy kids. I'll be praying for the same result."

9 / 10
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31 Report
  • Cowboy...
  • Taken for 10 years or more
  • February 15, 2016

"I have been taking Phenergan for relief of nausea for years. When I use to suffer from chronic migraine headaches, Phenergan would not only help with the nausea but also help me sleep and help with the pain. Several years ago I was in the hospital for a bad post-op bone infection (from a compound fracture) and I had awful nausea and the current drugs of choice couldn't control it like Phenergan."

10 / 10
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19 Report

Frequently asked questions

  • Anonymous
  • September 25, 2010

Phenergan (promethazine) "For uncontrolled nausea and vomiting that has been diagnosed as a migraine variant, the Phenergan suppository is the only medicine that works. It put me to sleep and and helps to greatly lessen the nausea. This medication works! Getting a physician to understand the diagnosis is not always easy."

10 / 10
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27 Report
  • Prome...
  • Taken for 1 to 2 years
  • November 10, 2015

"I was prescribed this medicine about a year and a half ago to get over a stomach bug. Then, when I got Clostridium Difficile a year ago, I asked for this medicine again. I have an undetermined stomach condition that I've had since I can remember. It makes me feel nauseous often. My doctor gave me a refillable prescription of Promethazine. Every single time I take promethazine, my nausea is gone in 40 minutes or less! It has been wonderful for me. It does make me sleepy, but its worth it for me if it stops the nausea. I take 1/2 of a 25mg tablet if I'm feeling only somewhat bad, 1 tablet if I'm feeling bad, and rarely two tablets if I feel extremely bad. It is the only thing I've tried that always works completely without fail. I love it!"

10 / 10
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Are you taking this medicine?

  • Hdav
  • Taken for less than 1 month
  • July 12, 2019

"I took one 12.5mg tablet and had the worst side effects, dizziness, not feeling able to hold my head up properly, nausea was worse, I felt like I couldn’t control my movements very well. I prefer Prochlorperazine so much more than promethazine! Wouldn’t give this medication to my worst nightmare! Would never touch this drug again!!"

1 / 10
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  • Irish...
  • Taken for 2 to 5 years
  • December 1, 2014

"I have had to take this to keep from being sick from vertigo caused by Multiple Sclerosis. It has worked very well if I catch it before it gets to the point of actually vomiting. A little dizzy means, "OMG! I HATE throwing up! Dive, dive, DIVE!" All while I throw myself at the bottle like I'm throwing myself on a live grenade to save my platoon. The ONLY reason it does not rate a ten is what I feel to be too long of a lag between ingestion, of a tablet, and the beginning of efficacy."

8 / 10
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  • Anonymous
  • August 25, 2010

Phenergan (promethazine) "I suffered from Cyclic Vomiting Syndrome; similar to an abdominal migraine. Gastroenterologist prescribed Phenergan suppositories as a prophylaxis. It prevented the onset of the nausea and vomiting. Just knowing it is it my refrigerator should I need it has stopped the cycle. "

10 / 10
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25 Report
  • Nite-...
  • December 17, 2016

"Started taking Promethazine at 25mg 3x daily yrs ago then to 4x daily for severe nauseous and vomiting from treatments for cancer and couldn't keep food down at all. I was also on strong pains before & higher w/cancer Oxycodone 30mg 4x day & Morphine 30mg ER twice daily for having 18 fracture vertebrae (8 herniated, 9 bulging had 1 ruptured disc repaired) an separate AC joint in right shoulder an other broken bones an left over bullet & shrapnel fragment in both legs & right foot due to 17yrs US Army 3 Combat tours. I found that the Promethazine didn't always work well as it should've at times I did go over an take couple more of them per day than what was prescribed. Didn't notice if it help w/pain meds. On them again cancer returned."

8 / 10
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16 Report
  • Anonymous
  • February 11, 2012

Phenergan (promethazine) "My wife has taken this medicine in pill form to combat nausea due to chemo, with no adverse side effects. Last week she was given a dose via her central line. She became psychotic and combative. Phenergan via IV was not good for her. Zofran is an excellent alternative."

1 / 10
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23 Report
  • Prome...
  • October 4, 2014

"I love this medicine as it works amazingly! I take it for nausea and I never feel even the slightest bit like vomiting. The first 10 or so times that I took it I went straight to sleep for around 10 - 12 hours. Now when I take it I don't get sleepy at all."

9 / 10
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  • mclai...
  • October 29, 2007

"I have had lot of surgeries and I take a lot of medication. When it comes to taking something for an upset stomach I have found that Phenergan is the best. Immediatly after taken Phenergan I no longer fill nausea."

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28 Report
  • Anonymous
  • October 26, 2009

Phenergan (promethazine) "I've had this prescribed for surgical procedures, with migraine medications and when I take opioids because they cause swelling and intense itching. THIS IS GREAT. It ends vomiting, suppresses nausea, eliminates swelling and itching. The generic is very inexpensive and works quickly. The drowsiness side effect is unlike most drugs with this caution; I can wake quickly and think clearly, no "drugged" or heavy, fogged thinking."

10 / 10
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  • sopra...
  • Taken for 6 months to 1 year
  • October 1, 2016

"Go to medication for nausea Makes you a tiny bit groggy but that side effect goes away.Its been around forever and I mainly use it with Excedrin when I have a migraine to subside the nausea.Only thing that comes near it is zofran and this is over $100 cheaper."

10 / 10
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  • Penni...
  • Taken for 5 to 10 years
  • July 8, 2016

"Although I prefer Zofran melt aways because it melts in your mouth and doesn't require you to drink anything (which can cause vomiting when your already sick) I love Phenergan! It works longer and although not as fast it works better. I use it for nausea and as a sleep aid because of side effects from other medications. It does lower your blood pressure which is a side effect I don't mind because of my constant high BP and the side effects of the BP meds.it's very effective and almost every insurance will cover the cost (zophran is rarely covered) overall I don't take it everyday but it's safe for me to say that I've had no bad side effects from prolonged use."

10 / 10
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  • Benja...
  • Taken for 10 years or more
  • October 28, 2023

"Whenever I feel nauseous, I take one 25mg promethazine tablet. Works every time and there are no side effects that accompany this medication. Usually, the nausea is brought on by a headache or when I'm having postnasal drip. It's much more effective than Zofran. I would definitely recommend it for the symptoms I've mentioned, but mainly nausea. It works every time."

10 / 10
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  • Yoe
  • November 18, 2009

Phenergan (promethazine) "I absolutely love this medication. I was sick often from chemo and this helped miracles. I also was having it for sleeping and when I took this I would fall asleep and with cancer you often just want to sleep and not be sick. This was great. I also had lots of morphine but decided I wanted this more then the morphine. So to me this was the better choice and I was in la la land but was my preferred drug and to this day I still ask for Phenergen."

10 / 10
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  • jek
  • April 23, 2012

"I am a male 50 years old and suffer from anxiety and depression. Out of the blue, I started experiencing severe nausea on a daily basis about 4 weeks ago. No matter what I tried or did, it hardly let up. It made me miserable, and due to the nausea and lack of appetite, I ended up losing about 10 pounds and I am slim already, so it greatly distressed me. I went to the ER twice, in early April and just recently. On the first trip they found an infection, treated it, but the nausea still continued afterward. On my second trip, they found NOTHING wrong with me and said I was probably creating it somehow with my mind. They put me on the Promethazine and for two days now no nausea. "

10 / 10
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  • Reser...
  • October 26, 2013

"Promethazine syrup is what I started out with. It used to real good for me to take away nausea whenever I would experience. After having used it for over 10 years, I feel like it isn't working as effectively as it used to be. I just found out that it has alcohol in it, and I know longer feel comfortable using it. I also own it in pill form (50mg). The pill is very strong and I find that it leaves me feeling lethargic, dizzy, and it creates stomach upset. I don't understand how a pill that's supposed to help you when your nauseous and sick can actually make you feel worse. The suppositories work the best for me. I don't have any side effects from it. And unlike a pill, I don't have to worry a out it possibly coming back up again."

9 / 10
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  • Silence...
  • December 3, 2018

"Because of chronic pain due to Spina Bifida, scoliosis, osteomyelitis, etc. etc. I abused (sorry) aspirin for many years, actually under a Doc's supervision because it was better than pain medications, and I destroyed my stomach even needing blood transfusions. So now, I am off all but one aspirin a day, but need to take antibiotics and blood pressure medicine, and what pain meds the state allows, so by nighttime my stomach is pretty raw. I swear by promethazine as being the only med I have ever taken that completely flatlines nausea and allows me to eat a meal. With promethazine, I gained back the 22 pounds I lost during my battle with MRSA. It does make you sleepy, and some people say it feels a little like a small dose of hydrocodone."

10 / 10
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11 Report
  • Vegas...
  • April 17, 2017

"I have been on Phenergan pills since damage from Brain surgery years ago. It is a life saver! The pills are the only option that works for me. I take it 3-4 times every day. I could not survive without it!"

9 / 10
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  • Toby
  • Taken for 10 years or more
  • February 3, 2019

"Was given this in college when I was in the ER with dehydration from a stomach bug. Eased the nausea and knocked me out— a bonus, as I didn’t really want to be awake while I felt so sick. It worked well for me as needed for nausea for several years, but about 5 or 6 years ago, it suddenly stopped working. I’d be heaving my guts out and falling asleep on the bathroom floor at the same time. I take Zofran for nausea now. I still keep the promethazine around for the sedative properties though. I just take it for a couple nights every once in a while to get my sleep patterns back in order."

6 / 10
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  • heave...
  • Taken for 5 to 10 years
  • May 7, 2013

"I have trouble with nausea and vomiting as well as severe coughing every spring or when the weather gets crazy. 6 years ago the doctor gave me some promethazine and after a few days the coughing a was just about gone. I tried everything and this really helped, but be prepared to sleep."

10 / 10
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17 Report
  • Anonymous
  • July 14, 2010

Phenergan (promethazine) "This drug is wonderful for stomach viruses, motion sickness, anything involving stomach nausea. The only side effect I have felt is the sedative effect. If you are a nervous flyer I would recommend 12.5 mg 30 minutes before take off."

10 / 10
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  • Almay
  • February 10, 2013

"I've been taking Phenergan for years now. It's a miracle medicine. I tried Zofran and it didn't work at all, in fact it made me get sicker. I suffer from extreme vomiting in all of my pregnancies. My dr. prescribed Phenergan to me and I'm so thankful for that. I LOVE this medicine."

10 / 10
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17 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Nausea/Vomiting

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