Prochlorperazine for Nausea/Vomiting User Reviews (Page 4)

• Zan...
• Taken for less than 1 month
• March 27, 2021

Prochlorperazine "Do NOT use Compazine!! I went to the ER for a severe migraine that lasted a week. They put me on Compazine, and within just a few minutes, I was shaking uncontrollably, couldn’t keep still, and had extreme anxiety, like if I didn’t leave the hospital RIGHT AWAY, my entire life would just go down the toilet. This was the only time I ever ripped out an IV. I called the nurse in, and I could only mumble “Oh God, what did you do to me” over and over again. After some of these other reviews, I count myself lucky that my symptoms only lasted a single night and the migraine did go away. But still, I will never take it again!"

• Anonymous
• Taken for less than 1 month
• November 30, 2017

Prochlorperazine "I went to the ER with nausea, they gave me Compazine immediately. I felt hot and restless. I freaked out, they moved me from the hallway to a room where I became restless and angry. My jaw locked up, and I was shaking uncontrollably. My heart raced, and I felt like I was gonna die. My symptoms lessened after about 8 hours, where I slept off and on. I went to a different ER, and they gave me a small dose of Ativan, but it didn’t make me feel any better. The next day, I still feel panicky, and my heart feels weird, and the shaking comes and goes. I also have horrible diarrhea. Worst experience of my life."

• Kad...
• Taken for less than 1 month
• April 2, 2019

Prochlorperazine "I've had three OHS (open heart surgeries), so I've had my fair share of IV medicine. NOTHING, and I repeat, absolutely nothing I have taken has made me feel as awful as this did. Five minutes after receiving the dose of Compazine, I started getting restless, like I wanted to crawl out of my skin. I complained about how uncomfortable I truly was, and the doctor just said, 'Oh yeah, that happens.' Please don't take this, it may have helped my pain. But here I am, 19 hours later, still feeling like complete garbage. I honestly wish I would have read these reviews first."

• pea...
• Taken for 1 to 6 months
• November 15, 2021

"I get severe nausea from IBS and anxiety, the only thing that has helped is prochlorperazine 5 mg! Don't be scared by these reviews, 95% of the bad reviews are talking about IV/injection prochlorperazine, which clearly reacts very differently to the much lower pill dose. Within 30 minutes, all of my nausea and most of my anxiety disappear, and it doesn't make me sleepy or dizzy either - unless I take more than one pill or take it with other medications that cause drowsiness. I never review medications, but I had to show that not everyone has a bad experience with this med."

• Pat...
• Taken for less than 1 month
• May 16, 2019

Prochlorperazine "It is absolutely horrible. I went into the ER yesterday with a bad headache on one side. They wanted to give me some cocktail that included Compazine and Benadryl combined. I said no. I should have done my research on Compazine prior to getting it intravenously. The worst mistake of my life. I had shakes, anxiety, which I don't have, the worst dry mouth of my life, that I almost choked on my sugar pill. I felt like it had been out in the desert for a year. I could not keep my mouth moist fast enough. It has been almost 24 hours, and I'm still not back to 100 percent yet. That drug is toxic. I would never, I don't care how much pain I'm in, ever take that drug."

• Iza...
• Taken for less than 1 month
• January 8, 2020

"Was prescribed this for an ongoing condition of vertigo to help with the nausea. I took two pills, and it gave me the worst anxiety I have ever experienced. It felt like I wasn’t even in my own body. I lost my appetite for about a week, my heart rate was through the roof, and it was a struggle to breathe properly. I’m only 20 years old, and it took me a good month to recover fully from this drug. Whilst my vertigo had gone the next day, the side effects were so much worse than the original problem."

• mom...
• Taken for less than 1 month
• October 31, 2022

Prochlorperazine "It has been a little over six months since I was given Compazine through my IV when I had a migraine, and I am still not right. It’s important to note that prior to the injection, I have never had any problems with mental health besides intermittent anxiety (mild). I went to the ER for a severe migraine that had been lasting a few days. I was given Compazine through my IV for the pain. I immediately had the worst panic attack of my life. I can’t even compare it to other panic attacks I’ve had because it was profoundly horrific. Wanting to escape, suicidal thoughts, terror, wanting to rip the IV out of my arm, and extreme restlessness. I have had debilitating anxiety ever since. After reading many of the reviews, I see most people feel better after a few days, but that hasn’t been the case for me. I have now been struggling with never feeling at peace or comfort. I can no longer feel love, happiness, joy, or even experience laughter. I walked out of that hospital a different person. Please avoid."

• Poo...
• Taken for less than 1 month
• March 23, 2019

Prochlorperazine "I went to the ER last night with nausea and vomiting. I was given Zofran, but it had soon worn off. I told the doctor, and he said he would give me something else. The nurse came in with the Compazine. She gave it to me through my IV. Within minutes, I started to feel really jittery and restless! I started to become anxious and fidgety, and I wanted to rip my IV out of my arm. The medicine worked for the nausea, but it's definitely not worth the side effects! It was the worst feeling ever!!! It has been 21 hours since, and I still don't feel right. The symptoms have calmed down a lot, but I'm still not 100%."

• Ang...
• Taken for less than 1 month
• May 17, 2018

Prochlorperazine "I have been given Compazine in my IV, and it was one of the most horrible experiences of my life! It almost immediately made me very anxious, I wanted to pull my IV out and just get out of the hospital! I felt zombie-like, and my face went numb. I had side effects like these for about 3 days! Never again will I take Compazine!"

• Anonymous
• Taken for 1 to 6 months
• August 3, 2015

Prochlorperazine "I was suffering from unexplained nausea for about a year. I tried a host of other anti-nausea medications, but nothing really seemed to be helping. My doctor gave me Compazine, which helped my nausea but made me exhausted by the evening and caused me to burst into tears at least once a day. I stopped taking the medication because the side effects were too much for me to handle."

• Yik...
• Taken for less than 1 month
• November 8, 2022

Prochlorperazine "Please don’t take this medication. They gave it to me through IV as a part of their useless “migraine cocktail,” which needs to be discontinued in and of itself. Needless to say, within 10 seconds, I was hot, sweaty, agitated - ready to pull the IV out, and I’ve had RLS before, this was a tad worse. The pure akathisia felt like hell. Then they gave me this as opposed to stronger meds because they were worried about me driving, but hell - if only they knew that this was more dangerous to drive with, maybe they would have reconsidered. This stuff makes you feel depersonalized, more sick, helplessly “under” (the best way I can put it), and the only way out is TIME. Benzos make it more tolerable (slightly). I’m on day two afterward, and I feel fortunate that I’m about 75 percent “back” from whatever hellish trip that was. It’s now on my allergy list. Lawsuit!"

• Hor...
• Taken for less than 1 month
• September 18, 2016

Prochlorperazine "The absolute worst experience with an antiemetic I have ever had. I literally panicked in the hospital to the point I almost pulled my IV out. Zofran stopped working for my hyperemesis gravidarum, but I would rather live with nausea and vomiting day in and out than feel the uncontrolled anxiety and restlessness I felt with Compazine!"

• Joh...
• Taken for 1 to 6 months
• December 25, 2019

"I have cancer and have been going through chemotherapy. I was prescribed prochlorperazine to reduce the nausea related to the chemotherapy. For this purpose, the drug did work. I would become less nauseous after taking it. This drug did come with a hefty list of side effects. It gave me chest pains like heartburn and a feeling of anxiety. It reduced my feeling in my face to the point where it felt like I was wearing a mask. I also had a hard time falling asleep, and when I was asleep, I had very vivid, crazy nightmares."

• Cat...
• Taken for less than 1 month
• April 4, 2019

Prochlorperazine "I thought I had the flu, so I went to the ER to get tested. It came back negative, but since I had a migraine, they gave me a “headache cocktail” which my sister had a bad reaction to, but I had forgotten (after all, I had a migraine and couldn't think straight). I got the IV meds, and one of them was Compazine...the awful liquid itself. Immediately, I had trouble getting comfortable, and my throat felt like I had a shrunken airway, but the doctors said it was just anxiety. So, it’s 4 in the morning, and I’m stumbling around the hospital waiting for my prescription and my stepdad to come pick me up, and I’m falling asleep any time I sit down. As soon as I got home, I fell into bed and couldn’t sleep unless my legs were writhing around. Then I slept off and on for almost 20 hours. I sweated most of the medication out, thank goodness, but I’ve never had anything like it happen before. I was by myself and was terrified. Why is this medication even still given?!?"

• dha...
• Taken for less than 1 month
• March 4, 2017

Prochlorperazine "I was given Compazine through the IV for nausea and vomiting while admitted. It was an absolute nightmare that still makes me feel pure fear when I think about it. I thought I was going to die. At first, my legs just felt restless, which I thought I was just having some anxiety, but then it really hit. I couldn't get my body to cool down, I started vomiting, then lost control of my bowels in front of the nurses. This lasted over six hours until they finally gave me something that knocked me out until it was over. I thought I was going to die. It scared both my partner, who was there, and myself to the point that I am now scared to take any more medications, fearing a similar reaction. They should really warn people about this drug."

• Mah...
• Taken for 10 years or more
• February 3, 2017

Prochlorperazine "I was talking to my sister about my bad reaction to a medication I took 15 years ago called Compazine. I took this prescribed medicine while at home. I remember my experience like it was yesterday. At first, I felt a twitching in my jaws. All at once, my bottom jaw started going to the right, and my top jaw started going to the left. I could not stop it, and I could not talk. In fact, my jaw felt like it was trying to break off my face. I remember the emotional and physical pain. My husband and I were both crying because we both didn't understand what was happening! My husband ended up taking me to another clinic, and they admitted me at once. So BEWARE! Just from talking - I found out this same medication hurt my sister just last year."

• LCa...
• Taken for 6 months to 1 year
• August 20, 2020

Prochlorperazine "I was first given Compazine orally for anxiety and nausea. It did not appear to have any side effects. A year later, I was hospitalized following surgery and was extremely nauseous, so after giving me Zofran to no avail, they gave me Compazine IV. It burned going into my arm. I became very agitated and restless, my body could not stop shaking, and I felt like I was going to jump out of my skin. Luckily, they gave me Benadryl, and that helped calm me down a bit, but it took a couple of days to feel myself again. Will never take IV again."

• Kat...
• June 23, 2020

Prochlorperazine "Took this for a migraine cycle, and while it helped with the migraine. When the nurse gave it to me, it made my heart race, and it made me have the worst panic attack. I couldn’t stay still because my legs were restless, and I was extremely hot and loopy. I won’t take this again."

• Cha...
• Taken for 2 to 5 years
• September 16, 2019

"I got two aural migraines in one day. I had never had nausea before from migraines, but all of a sudden, I had nausea, dizziness, vomiting, etc. My mum ran out to the chemist and got me these pills. Within half an hour, I was feeling so much better, it was unbelievable. It was my 21st party that night, and these pills saved me from missing out on the whole evening! I've also taken one tonight to help with nausea and dizziness from new antidepressants, and it has worked a charm."

• Mig...
• Taken for less than 1 month
• July 30, 2019

Prochlorperazine "This drug made me feel worse than any drug I ever received. I had a migraine and was at the A&E. It was pure mortal terror from the minute they went into my vein. I had them stop the infusion immediately, but it was too late. My heart rate shot up, and I felt like I was going to die right there on the bed. Sleep came on and off, but not because of being relaxed. More like passing out repeatedly. I slept for 24 hours and still feel pretty horrible the next day."

• Ash...
• Taken for less than 1 month
• July 2, 2015

Prochlorperazine "I was given this for migraines. I was stationed in Hampton Roads, VA, doing my time in the Navy. I had a TBI in Bahrain and was sent to Virginia for various medical treatments. I had blackouts and severe migraines that made me see spots at least 3-5 times a week. It was pure hell, so I thought. I would try to tolerate it the best I could, and I began frequenting the hospital where I received this drug. It took some time to figure out which drug I was having the horrendous side effects from. Portsmouth Naval issued me a 'cocktail,' as they called it, with this drug included. Over a few experiences with various doctors, I figured out this drug was the culprit. This drug made me feel like something terrible was crawling under my skin. 6 hours of hell."

• Ahr...
• Taken for less than 1 month
• October 31, 2016

Prochlorperazine "I had been suffering from severe nausea and vomiting on and off, including migraine, fever, and flank pain. It was my second time in the ER, so they gave me Compazine and I'd never had it, it relieved my nausea and migraine, but I started feeling so restless. I was freaking out, like I wanted to rip out my IV and leave and run away. Then they told me it's a side effect, and I already suffered from severe anxiety, it made it 1000x worse. I had the worst time trying to sleep, then had the weirdest dreams of my life. They gave me morphine shortly after, which calmed me a little and took the rest of my pain away, but I was hoping it'd honestly put me out. 24 hours later, and I still feel that restlessness in my body, but it's so much better than it was."

• bul...
• Taken for less than 1 month
• June 18, 2019

Prochlorperazine "I suffer from severe headaches on occasion, and usually Excedrin will do the trick. I had a headache several months ago that was there for 3 days. I finally broke down and went to the ER. They gave me Compazine and put me in a waiting room. Within five minutes, I felt terrified, like I had to get away. I told my wife to tell them to get my IV off me, or I would rip it out of my arm. They let me sign out AMA, and I fled the hospital. For several hours after, I felt like the walls were closing in and doom was imminent. I hate this medication and will NEVER take it again. Beware!!!"

• Men...
• July 3, 2019

"I feel obliged to leave a review after all the negative reviews on here, thankfully, I only found them after I had taken the medication, but it made for a very nervous first few hours while I was waiting for anything similar to happen to me. I am happy to say I had no negative side effects. I take the medication for Ménières when I get severe vertigo drop attacks, and if I catch it early enough, the pills stop me from going into full-blown vertigo, room spinning, and violently vomiting attacks. They also have a slight sedation effect on me, so they help me to stay calm while waiting for the vertigo to subside, and I end up having a good sleep after taking them. It's just a pity they take almost 30 minutes to start working because sometimes I don't always get early warning signs that the attack is going to happen. Other than that, they are a godsend for me."

• Thi...
• Taken for less than 1 month
• November 17, 2019

Prochlorperazine "I went to the ER for stomach issues as a teen, and I took it. Went home, and 45 minutes later my jaw shifted all the way to the left, and I couldn’t control it. My neck started leaning to the right. I was rushed to the hospital and given Benadryl through an IV. Lucky it worked, I was in so much pain."