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User Reviews for Prochlorperazine to treat Nausea/Vomiting

Also known as: Compro

Prochlorperazine has an average rating of 3.0 out of 10 from a total of 242 ratings for the treatment of Nausea/Vomiting. 19% of reviewers reported a positive effect, while 74% reported a negative effect.

Prochlorperazine Rating Summary

3.0/10 average rating

242 ratings from 267 user reviews.

Compare all 170 medications used in the treatment of Nausea/Vomiting.

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Reviews for Prochlorperazine

Manders · Taken for less than 1 month November 5, 2020

Compazine (prochlorperazine): “Another horror story about Compazine. I went to the ER with a migraine and neck pain that would not break. The doctor gave me their “migraine cocktail” and a few minutes later I started shaking. I struggle with anxiety and was obviously upset because of the headache, so at first I thought that was it. However, as time went on I got more and more agitated. I couldn’t sit still or stop moving my legs. I wanted to rip out my IV and leave! I even tried to disconnect it a few times. Eventually I just sat there, crying and rocking back and forth on my bed like I was going crazy. I told the doctor how I was feeling and she said it was common. She gave me some Ativan which helped after 2 or 3 hours. I’m so thankful I was able to sleep after that. What a terrifying experience. I will be putting this on my allergy list. Please check before you get a “migraine cocktail!””

1 / 10
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TransplantGal December 20, 2019

Compazine (prochlorperazine): “I was hospitalized for 4 days due to infection. Well, one of the nurses asked me if I felt nauseous and I shouldve said NO because I was barely nauseous. She gave me compazine over IV, and the worse feeling of dread, terror, anxiety, heart palpitations, restlessness, and panic took control over me for a whole week. Even, after I was discharged, I had extreme panic attacks even in the middle of the night. While at the hospital, I wanted to keep running away and scream, just to get away from the overwhelming feeling of HORROR. My husband had to keep praying for me. I couldn't sleep. The final night before the medicine finally wore off was when I started hyperventilating my husband had to literally slapped my face 4 times to calm me down! Because of that one medication, I developed a phobia of taking medicines and sometimes eating new food. I had never known panic or anxiety ever before compazine. It still grips me with fear”

1 / 10
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Tiffany · Taken for less than 1 month January 5, 2020

Compazine (prochlorperazine): “It’s been 2 weeks and I am still feeling the terrible side effects (pacing, tremors, etc) For those of you that have posted previously, can you please provide updates on how long it took to feel like yourself again? I need some hope that this will go away. :(”

1 / 10
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lxs124 March 19, 2021

Compazine (prochlorperazine): “I went to the Urgent Care for an especially debilitating migraine and was given some medication through an IV. Almost immediately I felt like ripping out my IV jumping off the TOP of the building!! Finally the nurse came in and kinda chuckled at my sobbing hysterical state saying that, "Some patients have this kind of reaction to Compazine but you can be glad it's all done." But for awhile after I kept going to the restroom thinking if I just did a "normal thing" like peeing I would suddenly feel "normal again" but I continued to feel panicked. I got Benadryl through an IV and I fell asleep. When I woke up I was FRANTIC to get out of there. I still had a bad headache and felt so panicky but had to get out of there because I was so afraid. I learned that reaction is called a PANIC ATTACK and have had several more since then. I still get migraines too but know to never again accept treatment at all similar to this nightmare drug.”

1 / 10
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Leigh · Taken for less than 1 month June 24, 2020

Compazine (prochlorperazine): “Do not take this medicine!!! I was given compazine (stemetil) in an injection I immediately had anxiety and my heart rate went up so fast. It’s now day 3 I still have inner restlessness and severe anxiety. Symptoms of akathasia. I’m hoping to goes away soon I cannot sit still I feel tired but can’t sleep. This medicine should be banned!!!!!”

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Lolo · Taken for less than 1 month March 23, 2020

“This medication worked wonders for me. I took 10mg for massive migraine and nausea. After 5 days with the worse headache and nausea, this brought relief within 20 minutes. For me, my experience was amazing and saved me a trip to the ER during all of this COVID-19 madness.”

10 / 10
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Akasurvive · Taken for less than 1 month November 6, 2019

Compazine (prochlorperazine): “Just for the record, the reviews on this site are absolutely real. I know because it happened to me, and I’ve talked to at least a heap people over the past 2 years who have experienced its bad side effects as well. This drug causes akathisia in some which is why so many of the reviews are similar. Just because it didn’t happen to you doesn’t mean it doesn’t happen. Compazine ruined my life and I only took it ONCE. Proceed with caution.”

1 / 10
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LM November 18, 2019

Compazine (prochlorperazine): “I can promise you these negative reviews are not false. Just because it didn't happen to you, doesn't mean it didn't happen to us. This medication is horrible! It should not be used for anything. I went to the ER a few years ago and my life hasn't been the same since. The panic attacks I developed after that medication were brutal. Never had panic symptoms before that night I went to the ER. It took me a long time to recover from that medication. Do not take it!”

1 / 10
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Ashley · Taken for less than 1 month October 28, 2020

Compazine (prochlorperazine): “I received Compazine, via IV, in hospital for vomiting. Within 20 minutes I was pulling off my clothes, my heart was racing and I was having suicidal thoughts. I was legitimately in a full blown psychotic attack, which has never happened before. Hours later I still felt jittery anxious and could not sit still. I will NEVER take this medication again. It stopped my vomiting, however; I’d rather vomit that experience psychosis. Worst experience ever. Never again.”

1 / 10
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Itsyaboi · Taken for less than 1 month January 5, 2020

“ I took this medication in a 5mg tablet for nausea and dizziness. Really worked - no nausea or dizziness and felt fine. Had a couple aches in my arms but meh beats feeling sick and dizzy. The medication did what it’s supposed to and this is coming from a hypochondriac himself who experiences side effects on almost everything. Take it, it might work for you.”

10 / 10
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Ange February 14, 2021

Compazine (prochlorperazine): “I have migraine, vomiting, gallbladder issue's. I was asked if I wanted zofran or compazine. I asked little bit about side effects and the nurse said it's for migraines, vomiting, put in my IV 15 minutes later, like the room got dark, and i couldn't stay still. 30 mins later I called my mom crying telling her I'm dying there is no way I'm coming back from hospital. Many times I was about rip IV out pacing the hospital bed with IV cord on me. I felt the oncoming sense of doom, somewhat dismembered my IV on my arm, one point I was rip IV out, had no ride home hour away from home. I was going run outta the room in the streets zero below. I got a nurse in said yah the medicine can do that to people have reactions. Benadryl, reverse it it took 30 more mins for them to bring benadryl in, about 10 mins I finally dozed off. But I still couldn't stop moving walking around and nervous panic. I had got released, I had toget Benadryl from store keep it reversed for 24hrs. Worse dangerous drug. I will never take a unknown medication again.”

1 / 10
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Tabitha · Taken for less than 1 month August 29, 2018

Compazine (prochlorperazine): “Reading all the posts make me feel less crazy. I highly advice everyone to not take this medication. I have anxiety and I have panic attacks, so I thought it was just me but I have never had one come on so terribly for no reason. Then I realized it was the medication. I was given that with benadryl through an IV. Within 30 minutes I was restless. I panicked. I had an overwhelming feeling to rip out my IV and run. I wanted to be home. I was crying hysterically begging to go home. My teeth wouldn't stop chattering and I couldn't stop wiggling around. It was a very bad and overwhelming experience. The practitioner then let us know that can happen with this medication. I also learned it's for anxiety and schizophrenia but I don't understand how when it makes you feel so very upset and out of body. I will never take this again.”

1 / 10
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Dani · Taken for less than 1 month July 16, 2019

“I’m so surprised reading all the reviews of this drug! One evening I opened my eyes, and the room was just SPINNING - I was terrified and couldn’t even get up or walk. My roommates had to help me to the doctor where I was diagnosed with vestibular neuritis with vertigo. The doctor wanted to prescribe me regular gravol but I insisted I needed something more, I was so horribly sick. He prescribed me 5mg of prochlorazine and I found it helps to prevent vertigo attacks as well as really helps manage them. I have panic disorder, chronic anxiety & depression and I haven’t experienced any of these side effects! I find it actually relaxes me and takes care of the nausea and dizziness quick. Maybe I’m just psychotic and meant to be on this med! Haha”

8 / 10
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Smorrison48 · Taken for less than 1 month July 4, 2021

Compazine (prochlorperazine): “I was given compazine along with tramadol via IV at the ER to help treat a bad migraine. As soon as they put it in my IV I wanted to rip it out and leave. My mom was with me and I stayed a few more hours until my bloodwork came back. I finally got discharged and just wanted to go home and sleep but of course I couldn’t. I was jittery and shaky. I was pacing back and forth in my room. I couldn’t sit still. I can’t find the words to describe exactly what I felt but I basically felt so uncomfortable and like I was going insane at the same time. I went back and they gave me a Benadryl which did absolutely nothing. Luckily my mom had some left over lorazepam which finally gave me some relief and allowed me to sleep. It took 2 days for the worst of it to wear off but now 6 days later I still don’t feel 100% back to normal yet. I will never take this medication ever again and I hope it gets taken off the market soon. I hope no one else ever has to experience what I did.”

1 / 10
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ZanarkandStar · Taken for less than 1 month March 27, 2021

Compazine (prochlorperazine): “Do NOT use compazine!! I went to the ER for a severe migraine that lasted a week. They put me on Compazine and within just a few minutes I was shaking uncontrollably, couldn’t keep still, and had extreme anxiety like if I didn’t leave the hospital RIGHT AWAY my entire life would just go down the toilet. This was the only time I ever ripped out an IV. I called the nurse in and I could only mumble “oh god what did you do to me” over and over again. After some of these other reviews, I count myself lucky that my symptoms only lasted a single night and the migraine did go away. But still I will never take it again!”

1 / 10
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Rita February 29, 2020

Compazine (prochlorperazine): “I was given Compazine IV in the ER ( which I work at the hospital ) for a severe migraine. Not much later after I started getting horrible sensations in my head. And creepy crawly all over. Couldn't communicate. Couldn't walk straight. And NO ONE noticed this !!!!! I was too sick to even realize it was the Compazine at the time. I had no idea it is in the THORAZINE family !!!!! Now I'm marked as having an allergy to COMPAZINE. NIGHTMARE !!!!!!”

1 / 10
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Lou · Taken for 1 to 2 years September 13, 2020

“I was prescribed this prochlorperazine as I suffer migraines to the point of uncontrollable vomiting. Side effect from meningitis when I was 15 years old. I have ADHD/ Aspergers/ Social Anxiety. Ex party drug user too. No side effects except a dry mouth. I feel a lot of these comments talk about it being administered via IV which would hit your system like a catapult. No thanks. I took tablets and can’t say a bad thing. Nausea gone super quick, and overall I feel this drug works wonders but not if you’re not aware of your incoming anxiety/triggers etc. I know when my anxiety flares on and off medications. I had one moment of a mopey feeling but I recognised it and altered what I was doing so my thought process improved. Learn how your body works. Properly; and therefore most prescribed medications can work in your favour. Drs are drs for reasons. ”

10 / 10
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MM February 18, 2019

Compazine (prochlorperazine): “I went into the ER for a migraine. The nurse gave me a "cocktail" of meds: Toradol, Compazine & Benadryl. He told me my migraine should be gone within 15 minutes. BUT Within minutes of the Compazine being given to me through IV, I felt the worst I have ever felt. Agitated, restless, scared. It was the worst anxiety/panic I have felt. I wanted to die so bad. I NEEDED help and I kept calling out and they just told me "it'll wear off". I was hollering and crying and upset and absolutely terrified. I couldn't stop shaking, I wanted to rip my IV out and run out of there as fast as I could. It's been 2 weeks and I still don't feel like myself. I have these bursts of panic and nausea, I feel completely and utterly distraught. I told my doctor about it but they just dismissed me. I'm scared this feeling will never go away. It was completely traumatizing and I don't recommend this to anyone ever. I do not wish this on my worst enemy & you couldn't get me to take this again for a billion dollars.”

1 / 10
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sadsally January 19, 2019

Compazine (prochlorperazine): “Background info: I have a long medical history of generalized anxiety disorder & panic attacks. This medication caused THE WORST mental AND physical distress I’ve experienced in my entire life. I am not exaggerating; this was beyond any panic attack I’ve ever had, almost to the point that “panic” doesn’t suffice to explain what I felt. Every muscle in my body was tense & cramped, to the point that I wanted to crawl out of my skin. My stomach was clenched, & despite this being an anti-emetic, I felt like vomiting. I could not sit still or get comfortable, & ended up pacing like a lunatic for hours. I felt horribly self-conscious & emotionally distraught, & truly wished that these terrible feelings would end. PLEASE, stay far away from this medication!! Even if you’re not an anxious person, don’t risk it. I’ve been through some horrible things in my life, but the feelings that Compazine caused me are very near the top of the list.”

1 / 10
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El · Taken for less than 1 month April 2, 2021

Compazine (prochlorperazine): “I’m honestly shocked this drug is still allowed to be administered. I have several chronic illnesses including mitochondrial disease, Ehlers Danlos syndrome, dysautonomia, gastroparesis, Migraines and more. Four years ago at 14 I was taken to the emergency room with a severe headache along with nausea and stroke like symptoms. I was given the migraine cocktail that included Compazine. I immediately felt a rush of adrenaline accompanied by the worst restless leg/body/burning sensation I’ve ever felt. I remember wanting to literally crawl out of my skin. I felt as though I was going crazy. I have been septic and close to death many times but genuinely cannot think of a more uncomfortable experience than being on this medication. It took 50 mg of IV Benadryl +3 mg of IV Ativan to get me to finally calm down”

1 / 10
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AJO · Taken for less than 1 month December 10, 2019

Compazine (prochlorperazine): “Y’all, my experience was exactly like so many others. I was having dizzy spells for over a week and then suddenly had the worlds worst headache so I went in. They gave me toradol and compazine through an IV and within ten minutes, I thought I was going insane. I asked to go to the bathroom just to get out of the room. I couldn’t sit still and felt so panicked. On my way back from the bathroom, I seriously considered ripping out my IV. When the nurse came in, I stopped my fluids, and went home. Had to sign a paper that I was refusing treatment, but I couldn’t be in that room any longer.”

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Birdie · Taken for less than 1 month August 23, 2020

Compazine (prochlorperazine): “Went to the ER with extreme dizziness. They wound up giving me Compazine. I wasn’t even familiar with what it was. I felt strange at first, but then my hands contorted & froze. My mouth had almost completely clamped shut. An orderly or a CNA just happened to come by to empty trash. I barely was able to say please go get someone something’s not right. The dr at first thought I had stroked. He ran some test gave me some Benadryl which helped. I would never take this drug again.”

1 / 10
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Lacey October 8, 2019

Compazine (prochlorperazine): “I went into the ER for a really bad migraine and vomiting they gave me Benadryl and compazine within three minutes I had the worst panic attack of my life. My anxiety was through the roof. I unhooked myself from everything that I could and tried to get my IV out and demanded that I be let go thinking I would feel better when I got home. I have not slept in over 24 hours. I'm now on day 2 and I still want to crawl out of my skin. I can't stop shaking and crying. I want to crawl out of my skin or run away to get away from this feeling. I'm also shaky and anytime I think I'm about to fall asleep I get weird sadistic images that wake me up right away before I'm even all the way asleep. I don't know why this drug is legal. I hope people read these reviews and please don't let any doctor give you this medication the worst feeling of my life”

1 / 10
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ThatGuy July 18, 2019

Compazine (prochlorperazine): “Believe the reviews! Do not under any circumstances when going to the ER for a migraine/headache have them give you prochlorperazine through a IV. When it was given I had an insanely fast heart rate, my skin was crawling, and I literally stood up asked the nurse to remove my IV and I paced the hospital non stop. My wife drove me home and I literally paced my house for almost 3 days straight as I couldn’t sit still or sleep! It’s been a month since then and I’m still having PTSD from that incident.”

1 / 10
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Never. Again. · Taken for less than 1 month November 13, 2016

Compazine (prochlorperazine): “They gave me this medication via IV in the ER for a very intense migraine and extreme nausea, I would never recommend this medication to anyone ever, the second it was pushed through, I started having an extreme panic attack, something like I have never felt before, like a huge wave of doom rushed over me, I started freaking out so badly I almost ripped my IV out and ran away, it was so traumatizing to me that they pushed a big dose of Ativan though my IV just to knock me out, I truly thought I was dying... And after all that it felt like my skin was crawling for a good 32 hours. No, thank you. Never again will allow this in my body.”

1 / 10
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