Pregabalin for Migraine Prevention User Reviews

• bri...
• Taken for 1 to 6 months
• January 18, 2025

"I had not even considered taking pregabalin for migraine prophylaxis until I had a different GP than my usual GP suggest it, and I am so glad I tried it. I started it 40 days ago, and I haven't had a migraine since commencing it. I am on 25 mg twice a day, so a very low dose. I was previously having 1-2 migraines a week, each lasting 2-3 days and 8/10 searing pain that left me incapacitated. I had previously tried beta blockers, calcium channel blocker (verapamil), antidepressants, pizotifen, triptans, opioids, steroids, NSAIDs... the list goes on. Prior to pregabalin, I was using daily aspirin with good success, however, I developed an allergy to it and had to cease use. My main side effects have been some short-term memory issues and brain fog, and some tiredness. No weight gain for me."

• bob...
• June 18, 2015

"I have constant migraines, often lasting months. First trialed Lyrica for 1 week without any effects (75 mg x 2 a day). After trialing other prevention medication, which had bad side effects. Trialed Lyrica 25 mg twice a day, and after the first week, was migraine-free for months. After running out, migraines returned. This is very effective, as all other migraine prevention medication has been unsuccessful."

• Jan...
• Taken for 1 to 6 months
• August 6, 2024

"I have had migraines my whole life, but they became chronic and daily over 10 years ago. I have tried every medication available, none of which helped except CGRPs, which I had to stop due to a severe allergic reaction. I started pregabalin at the age of 49 primarily for pain, as I also have fibromyalgia. I have been on it at a dose of 100 mg for a month now and haven't had a single migraine!!! This is unheard of for me and has literally given me my life back. I haven't had any side effects and am sleeping better, less anxious, and my pain levels have significantly decreased."

• MFa...
• Taken for 5 to 10 years
• February 18, 2019

"Pregabalin is a godsend. After years of migraines and taking every tablet under the sun, I was prescribed this by my nurse practitioner, started on once daily, and increased gradually to three. I had to go back down to two as it made me too sleepy. I had migraines 2 or 3 times a week and symptoms so severe they were taking over my life. I've been taking it for about 6 or 7 years now, still get odd migraines, but it really has changed my life."

• Bri...
• Taken for 1 to 6 months
• February 23, 2025

"10/10 would recommend for migraine prophylaxis. I am an RN with an 18-year history of the worst migraine disease, landing me in the hospital and ruining my life. Tried about 7 different preventative medications, with varying effects, but never full remission of migraines. A GP recently suggested pregabalin, and now I'm just regretting not trying it 10 years earlier, I just didn't know it could be used for this. I have had one migraine since starting this medication 4 months ago, and only two other small headaches. Prior to starting, I was basically having migraines on most days of the week and was feeling suicidal. It seems to have a calming effect. My only side effects are feeling a lot of brain fog and some issues with my memory, my daughter says, 'Mum, there's something wrong with your brain!' But I'll take that over severe and unbearable pain and disability. I just set more reminders and to-do lists :)"

• Anonymous
• May 10, 2008

Lyrica (pregabalin) "I have tried several medications for migraines and started Lyrica three months ago. Other than the weight gain, I am very happy. Lyrica makes me feel ravenously hungry all the time. Actually, this past doctor's appointment, I was also prescribed Meridia and have experienced a loss in appetite, and I hope this will get me back to a more comfortable weight."

• Har...
• December 21, 2011

"I usually have bad migraines that knock me out for a day or two every week. Today I had the aura, the nausea, and all my senses started feeling fuzzy like they do when it's coming on. This time, the troubles went away in an hour, and I was left with a minimal headache. This is on Lyrica 2x75mg daily, that I actually take for social anxiety disorder/generalized anxiety disorder."

• Ell...
• October 26, 2018

"After trying every migraine medication under the sun... which were only taken once the migraine started, none of it worked. I did this for years. I’ve had horrible, debilitating migraines since I was 12 (I’m now 31). A year or two ago, I heard about the off-label use of Lyrica in migraine prevention. And prevention is what I wanted! I was tired of taking meds only after a migraine started. I started with a low dose and slowly increased it until I found the amount that worked for me. It has helped tremendously! I take 100 mg twice a day and I haven’t had one since! The medication is truly a godsend in the prevention of migraines. The side effects of the medication went away about a week of taking it— my body adjusted to it greatly. I highly recommend Lyrica as an off-label use of the prevention of migraines. You’ll need to work with your doctor as to what dose works for you; adjusting it until you find the relief."

• Anonymous
• February 10, 2011

Lyrica (pregabalin) "When I started taking Lyrica for my migraines, my 'episodes' were less severe and lasted a shorter amount of time. I have not experienced any of the side effects. So, for me, Lyrica has been a big help."

• Anonymous
• September 8, 2009

Lyrica (pregabalin) "Tremendous reduction in pain. I have been on the medication since May and have gone from bone-shattering pain at the bridge of my nose and between my eyes 24/7 to only two or three bad headaches a week. I have just had my dose increased to knock even those out, I'll let you know how much better I feel in four months. I would have given it a 10 if it wasn't for the weight gain."

• Rik...
• Taken for less than 1 month
• November 23, 2017

"After 20 years of worsening migraines and fibromyalgia symptoms, pregabalin has been a miracle. I have gone from suffering 2-3 debilitating migraines per week to zero migraines. Yes, zero! 50 mg per day was not enough, so my neurologist raised the dose to 100 mg/day, and that is just right. It took just over a week for the drug to kick in. Pregabalin also helps regulate my adrenal glands and calms my Crohn's/IBS symptoms. I feel like a new person after suffering for so many years. Initial side effects were feeling stoned and wonky vision that made it hard to read. My body adjusted after a few days. I sleep deeply all night and no longer snore. Bladder gets real full as kidneys work hard to eliminate the drug. Fibromyalgia pain is 95% gone."

• Max...
• Taken for 1 to 6 months
• June 30, 2023

"Pregabalin has been an amazing medication. I've tried many medications (Topamax, propranolol, B vitamins, Emgality), and none have caused much relief. A 50mg pregabalin made a difference in only a week or two. And with basically no side effects, I'm able to keep taking this and even increase the dose. I'm at 100mg twice daily, and I couldn't be happier. There should definitely be more research done on pregabalin and maybe less focus on Topamax/Elavil, which are way less tolerable."

• Blu...
• Taken for less than 1 month
• September 2, 2017

"Had migraines for years, tried pitzotifen, gabapentin, sodium valproate, triptans, co-codamol 30/500, topiramate, been on 75mg pregabalin, an off-the-books trial using the doc's words. I'm in the UK, 7 weeks migraine-free. I normally would have had 6 attacks in that time, works for me. A bit of fatigue, only side, I'll take that over the debilitating effects of a migraine anytime."

• HRa...
• Taken for 1 to 6 months
• April 24, 2020

"For more than one month, I was suffering from migraine-type headache. But the diagnosis most probably was occipital neuralgia. All the medications over the counter helped, but still suffering every day with severe headache. After starting Lyrica 75 mg twice a day, I am a new person, almost no headaches, I am so happy. Adverse effects I noticed: dry mouth and, for a few days, blurred vision (a little)."

• Anonymous
• February 13, 2011

"I am a migraine sufferer, and I was prescribed pregabalin over a year ago for neuropathic nerve pain in my foot. Not a single migraine over this time, but unfortunately, and because of all the side effects, I had to come off it. Yes, the migraines returned with a vengeance. I have just started taking pregabalin again, one 25 mg capsule every three days as an experiment, and, touch wood, I think it's helping. It's too early to tell if it will be of any permanent good as I've been borderline with the vision thing a couple of times, but fingers crossed. My pain management consultant and my GP thought I was joking at first and were quite surprised."

• Spl...
• Taken for 1 to 2 years
• September 1, 2019

"Migraines are less frequent and less severe on pregabalin. I still have about 2 days of migraine a week but am not wiped out and recover more quickly since taking 175 mg daily. I have had no side effects at all. An added bonus is that pregabalin has eased my anxiety so that I feel able to make plans without worrying about getting a migraine."

• Mic...
• Taken for less than 1 month
• November 21, 2019

"Never found out if it would work. Started at 25 mg/day, made me dizzy and brain foggy with some depersonalization (all listed SEs), but tolerable. Began to get restless legs (which I didn't have before, and which Lyrica is used to treat! Weird). Within two weeks, I got a bad cough (cough producing mucus, and infections are listed side effects), which quickly turned into bronchitis. Stopped the med, went back to the neurologist four weeks after stopping (STILL COUGHING but improving), and he wanted me to retry, as I work with kids and might've just caught a bug from them. Restarted every second day, 25 mg. Dizziness, brain fog, depersonalization, and RLS back with a vengeance, and by a little over a week, the cough is taking a bad turn again. Coming off it, I had my first visual aura ever. I have migraine with aura, but never had a traditional visual aura before. A miracle for some, but obviously not for me."

• Cyn...
• July 30, 2017

"I was on this drug for many years, and while in the beginning, I felt it helped with both the frequency of headaches and fibromyalgia associated with ME, over time it stopped working. On the flip side, it definitely had a negative effect on my memory. I VERY slowly weaned myself off of it, and most of my memory has returned. My insurance only paid a small part of the cost, and it is very expensive. I would not use it again. No upside and plenty of downside."

• Tid...
• Taken for less than 1 month
• April 18, 2018

"I have never written a drug review in my life, but thought I should with this one. I suffer from migraine and nerve damage in my legs following chemotherapy. I was told to take only 25 mg at night and build up slowly to 75 mg. I only managed to take 25 mg for 2 weeks before quitting. This horrible medication is great if you want to fall asleep all day and turn into a zombie because that is all it did to me. I did have some slight relief, but whilst on this medication, I didn’t really care as it melted my brain. It also gave me blurry vision after a week, which wasn’t nice. I am trying another drug now. It may help you, but do your research as this drug has bad press."

• RED...
• September 16, 2008

Lyrica (pregabalin) "This has worked wonderfully to prevent my migraines. I went from having them 3 times a week to maybe once a month."

• Anonymous
• August 6, 2010

Lyrica (pregabalin) "I was on Lyrica 50-75 mg 2-3x/day for fibromyalgia for over a year. Incidentally, I didn't have any migraines while on it. I stopped Lyrica 7 months ago and have had migraines monthly since!"

• PM2...
• Taken for 6 months to 1 year
• April 3, 2023

"I had it prescribed for arthritis pain, but it appears to be preventing migraines as well. Very effective."

• Bar...
• March 3, 2021

"I use pregabalin for my migraines, it really helps."

• Pen...
• Taken for 1 to 6 months
• February 22, 2018

"Caused migraines once the medicine wore off. Meaning I am getting migraines every day now until the pregabalin dulls the new migraine again, except it comes back worse than the day before."