Nardil and Constipation: What Users Say

• rav...
• Taken for 10 years or more
• September 16, 2024

For Depression "There are many, many antidepressants, but then there's Nardil—one of a kind. This medication obliterated my major depressive disorder (MDD), which was so severe that even getting out of bed was a monumental task. I had a lack of motivation, anhedonia, constant suicidal thoughts, and feelings of overwhelm and doom. Nardil put a stop to all (and also eradicated my social phobia). For me, 60-90 mg is necessary, and it takes a while to work—took about 8 weeks the first time. The side effects were manageable, mostly vertigo, increased appetite, and constipation. In over 20 years, I haven’t had a single negative experience with the dietary restrictions. I eat what I want without issue. I've tried coming off Nardil three times: twice in an attempt to be medication-free, and once to try Parnate. The first two times, I didn’t experience withdrawal symptoms, but my depression and anxiety returned. The third time, Parnate provided some relief, but wasn't nearly as effective as Nardil."

• Bub...
• Taken for 1 to 6 months
• July 30, 2016

For Depression "After trying every other kind of antidepressant over the past 9 or so years, Nardil was my first try at an MAOI. The dietary restrictions were less difficult to get used to and less strict than they appeared at first. I was on 30 mg of Nardil a day and didn't notice any effect, but after increasing to 45 mg/day, I felt the best I've felt in years, and it seemed that my depression might be cured at last. ...however, I also had the most side effects I've ever had from a medication: constipation, difficulty urinating, insomnia, and inability to reach an orgasm. Because of the bladder issues and insomnia, I've been forced to resume my search."

• Ast...
• Taken for 1 to 6 months
• March 19, 2020

"I wasn’t diagnosed yet with bipolar. This was my first visit to my psychiatrist to treat my bipolar depression, which I thought was major depressive disorder. We went up to 90 mg Nardil because it wasn’t taking effect. Holy crap, did it feel amazing, but I was in an extreme state of mania. I spent so much money. I was delusional. It was not good for me. Way too strong, this is serious stuff. The diet sucks. I gained a lot of weight and literally could not poop. I had to take laxatives regularly. My appetite was also affected big time. All I wanted was cookies, cakes, any sweets I could get. I came off it because I could not ejaculate for the life of me. That was the tipping point after a few months. I got off it. I do not recommend this for anyone with bipolar 1 especially, nor for bipolar 2."