Paliperidone and Hormonal Changes: What Users Say (Page 2)

• Ann...
• Taken for 6 months to 1 year
• July 18, 2021

Paliperidone for Schizophrenia "This drug works really well to control my positive symptoms like hallucinations, delusions, and paranoia. I still have breakthrough symptoms, but only when very fatigued or stressed, but nowhere near as intense as off medication. I have managed to lose 2 stone (in 6 months) of the 6 stone I put on from taking the Abilify injection. I feel less fatigued, and insomnia isn’t as bad as when taking the other medication. I still have less interest in social situations and relationships, and my sex drive is nonexistent compared to before my illness. All 3 are symptoms of schizophrenia I know can be made worse by medications like these. The main negative is it has increased my prolactin levels to 4 times that of a healthy non-pregnant woman."

• Mon...
• Taken for 6 months to 1 year
• April 19, 2023

Paliperidone for Schizoaffective Disorder "Since taking Invega Sustenna 150 mg, 4 weekly injections, I have gained 10 kg even though I was eating a raw and plant-based diet. I have a flat affect, anhedonia, weight gain, high prolactin, and amenorrhea. I am also feeling slowed in my thinking and lack the motivation or inspiration to do anything. My psychiatrist refuses to put me back on the 3 mg tablet, which I thrived on without symptoms for over a decade. I researched my illness, and now that I have insight into my illness, I should be allowed to remain stable on a less lobotomizing medication dose for Schizoaffective Disorder."

• Bob...
• Taken for 5 to 10 years
• September 27, 2022

Paliperidone for Schizoaffective Disorder "Been taking it since 2016, it is great at keeping psychosis at bay. However, the main side effect I have had is high prolactin levels. This month, I'm talking to my doctor to switch to Abilify, which keeps prolactin levels in the normal range, unlike Invega."

• jel...
• May 24, 2015

For Schizophrenia "I have been on this paliperidone for 2 years. It's the best for managing the voices and delusions. They stopped and went away very quickly. Side effects were lactation, increased sex drive, and insomnia. I would recommend it to anyone who needs it because it works very well."

• Ano...
• Taken for less than 1 month
• August 27, 2025

Paliperidone "I didn't want to go into too much detail, but I haven’t seen anyone else on here write about this as an off-label drug for just bipolar, so. I don't know where to start; let’s just say I’m super sensitive to like every medication. If I counted right, this is my 12th med change in the past 2 years. We tried this one off-label in an effort to find something, anything, that my body tolerates and that also keeps me out of mania. Well, I tried Zyprexa in the past and lost my period on it for a full 6 months before we finally decided to come off because I’d also gained 40 pounds in like 4 months. Anyways, I was hesitant to try this drug because I knew that it also makes prolactin levels high. We put me on the smallest dose possible, and here I am two weeks later, and I am lactating. My prolactin level when I drew my blood today was at a 65. For reference, I am 19 years old, and as a 19-year-old woman, it shouldn’t be higher than 20. Prior to the drug, it was only at like a resting 7.t"