Paliperidone Alternatives Compared
| Paliperidone | Vraylar (cariprazine) | Rexulti (brexpiprazole) |
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| Paliperidone | Vraylar (cariprazine) | Rexulti (brexpiprazole) |
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Prescription only
Prescribed for Schizoaffective Disorder, Schizophrenia, Bipolar Disorder, Autism, Borderline Personality Disorder, Depression. Paliperidone may also be used for purposes not listed in this medication guide. View more |
Prescription only
Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar I disorder. Vraylar is usually well-tolerated and less likely than some other antipsychotics to... View more |
Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Related suggestions Schizophrenia
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| More about Paliperidone | More about Vraylar (cariprazine) | More about Rexulti (brexpiprazole) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Paliperidone has an average rating of 4.5 out of 10 from a total of 650 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 52% reported a negative effect. |
Vraylar has an average rating of 6.1 out of 10 from a total of 533 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 32% reported a negative effect. |
Rexulti has an average rating of 6.6 out of 10 from a total of 499 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 25% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Paliperidone side effects |
View all Vraylar side effects |
View all Rexulti side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Paliperidone prices |
View all Vraylar prices |
View all Rexulti prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Erzofri, Invega, Invega Hafyera, Invega Sustenna, Invega Trinza |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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23 hours |
504 hours |
91 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 631 drugs are known to interact with Paliperidone:
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A total of 579 drugs are known to interact with Vraylar:
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A total of 601 drugs are known to interact with Rexulti:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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December 19, 2006 |
September 17, 2015 |
July 10, 2015 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.