Omeprazole and Depression: What Users Say (Page 2)

• Dee...
• Taken for less than 1 month
• March 16, 2021

For Indigestion "Took this medicine for 8 days. On the third day, started to feel awful. Brain fog, high anxiety, and depression. Blurry vision and a tingly feeling in hands and feet. I have now been off of it for 5 days and feeling like I’m losing my mind. I can’t work. I’m going to check my B12 levels tomorrow to determine if I am deficient. I hope this passes or eases up soon because I can barely even sleep. I thought it was a reaction to my first vaccine (Pfizer) until a friend told me omeprazole did this to him as well. What an awful drug. I’d recommend an all-natural remedy over this any day."

• Han...
• Taken for less than 1 month
• April 27, 2020

For Laryngopharyngeal Reflux "I just started omeprazole about a week ago. I got prescribed it for my acid reflux. I’ve had the worst stomach pain, diarrhea, nausea, and depression. I’d honestly rather have acid reflux than what I am going through currently. I truly don’t recommend this. But then again, everybody is different, and I'm sure it works good for some."

• Isa...
• Taken for less than 1 month
• September 7, 2021

For GERD "I was on this medicine for 3 weeks, ever since I missed my period, fatigue, depression, diarrhea, headaches, cough, extreme abdominal pain (feels like a constant dull food poisoning feeling), and definitely mood changes. I was diagnosed with silent acid reflux GERD. I’m really hoping there is another medicine I can take or a home remedy I can try. Side effects from this medicine are not fun to deal with."

• RLS...
• Taken for 10 years or more
• January 29, 2022

For Indigestion "OMG! Reading all those reviews makes sense now, as I’ve had similar experiences by taking omeprazole only when I was getting a flare-up of a gout attack coming up, as I had to take 20 mg of it 1 hour before a meal and after a meal, colchicine, and Voltaren 100. Been doing this for the last 15-20 years, as I was diagnosed with gout nearly 30 years ago when I was 18 years old. It’s been happening lately, let's say a few years back, when taking omeprazole that I have been getting symptoms of chronic fatigue, blurred vision, extreme anxiety, panic attacks, brain fog, muscle cramps, severe insomnia, and depression. I cannot function at all, especially in the mornings when I wake up, and only start to function in the late afternoon after pushing myself to exercise, even with extreme fatigue, so that I felt better afterwards as my body would produce endorphins and serotonins. My GP prescribed me antidepressant drugs also. I still feel horrible now writing this review. :( THANK YOU to all of you for your reviews."

• And...
• Taken for 1 to 2 years
• November 30, 2019

For Indigestion "I have been experiencing extreme anxiety, depression, confusion, nausea, and muscle spasms for a while now. I have been visiting my GP and haven't been able to find a cause. I have just found this page and now realize that omeprazole may be the cause, I never thought it could be the cause because it seemed to help so much at first. Just hope stopping, I can finally get back to normal."

• Tir...
• Taken for 2 to 5 years
• November 19, 2021

For GERD "I’ve been on omeprazole for two years. First at 40 mg a day, then 80 mg a day. Recently, I’m having huge amounts of anxiety and depression, so bad it’s difficult for me to get out of bed at times. I can be driving down the road, and a huge rush comes over me like a massive hot flash, tightening of the chest, it only lasts for seconds. I’ve tried coming off of this medication, even weaning myself off, but the side effects begin to intensify when I do. I also have a hiatal hernia and IBS/GERD. No matter what you do, do not take this medication. I don’t know what normal is going to be like when I try to come off of it again."

• Sin...
• Taken for 1 to 6 months
• December 9, 2021

For Hiatal Hernia "Was worse off. Doctors were surprised that it caused depression and pain. Subsequent review by another doctor identified that omeprazole depletes the magnesium levels, and as a result, one may experience depression. Since I've stopped taking it, I do not feel that way. I now take digestive drops, which help with the reflux. I understand that as we age, our bodies may produce less acid, which may lead to some of the same ailments. Digestive drops are to produce acid for digestion. I am pretty okay now, but still have the hernia pain, not indigestion."

• Nan...
• Taken for less than 1 month
• November 5, 2019

For GERD "I’m on day two of omeprazole 10 mg. My heartburn for the past month was just horrible. I lived on Tums. I notice stomach pain and shakiness and anxiety. A bit depressed too. My heartburn is better, but which is worse, the heartburn or the anxiety and other side effects? I was on Prevacid for five years until I was diagnosed with severe liver fibrosis. Not even a drinker or diabetic. I didn’t realize how good I felt off of that, especially with the anxiety, till it was out of my system. So I’m at a point of what to do now? Hoping these side effects will go away with time:/"

• Joh...
• Taken for 1 to 6 months
• December 20, 2021

For GERD "Omg, where do I even start? I got an endoscopy, and the doctor said I have acid reflux and H. pylori. I was prescribed omeprazole (August 2020). It was okay for the first few weeks, then out of nowhere, I started belching nonstop, and I still do to this day. It caused me heart palpitations, headaches, brain fog, anxiety, depression, extreme weight loss. I stopped it and started taking anxiety medications. Everything is all good, then I just, 3 days ago (December 17, 2021), I wanted to try it one more time just because I had heartburn and acid reflux very badly, and it worked good the first day. 2nd day, same symptoms, never again in my life. Ever. Now we all know the reason why we all have the same problems. I went back to my GI doctor several times complaining. What did he do? Upped the dosage. OMG, never again."

• Sun...
• Taken for 1 to 6 months
• January 13, 2022

For Indigestion "The worst experience of my life, this drug. I was prescribed 40 mg per day. Was completely healthy all my life. No issues. All was OK for a few weeks until I started getting sensations of what I now know as anxiety. Tinnitus started then, and I started to feel I had constant kidney problems. Went off these cold turkey, and then the symptoms escalated. Severe weight loss over a 6-week period to the extent I had a biopsy. Could not eat solid foods for about 4 weeks. Kidneys were under huge pressure and had 4 antibiotics for infection. Jolting out of sleep at night, body tremors. Depression, never had anything like this in my life. I am now just over 6 months off of these toxic substances and am almost back to myself. The weight stayed off, but I can eat healthily now. I upped vitamin intake. I have researched this, and whatever these contain seems to work on the whole system - to the organs of the body and neurologically as well. Horrific and avoidable experience."

• Inp...
• August 12, 2020

"I have been taking this for a week now. I was put on omeprazole while they are still doing tests to find out what's wrong. Side effects are awful headaches, increased depression, and anxiety, but could also be from not knowing what is wrong with me. Two months of pain that is often so bad I can't do anything but curl up in bed and run to the bathroom. Food comes out explosively from both ends, and this little pill stopped that. I can go out and eat (no citric acid, no caffeine, no seeded foods)-not much left to eat, but I can eat without being sick. I'm always hungry and full of gas-also side effects from this pill. I don't want to take it for too long, as it has really bad side effects from prolonged use. Praying there isn't anything seriously wrong with my stomach. I do recommend it for temporary use."

• KaR...
• Taken for less than 1 month
• September 13, 2021

For Gastritis/Duodenitis "I was prescribed this drug by an NP to treat gastritis, at 20 mg daily for 30 days. I had been diagnosed with gastritis before and was told to take Pepcid daily, and I had no issues with that. The NP told me the only side effect I might experience taking omeprazole was diarrhea. In reality, what I experienced was a massive increase in anxiety, depression, and nightly panic attacks. My resting heart rate has gone up about 20 bpm after taking omeprazole for just 20 days. I am unable to fall asleep until well into the morning, so only 3-5 hours per night. I have had anxiety and depression for years, but never as intensely as it is now. I did not consider that the omeprazole was the cause of it! I started a new anxiety medication a little over a month ago and blamed it on my body adjusting to that. After reading these reviews, I am almost certain the mood and sleep disturbances I am experiencing are due to taking omeprazole. The acid in my stomach is reduced, but that could be my change in diet."

• Tja...
• Taken for 2 to 5 years
• August 8, 2021

For Erosive Esophagitis "After taking this medication on and off for 4 and a half years (but more recently on a higher dose), it had given me pain in the kidney, so I decided to lower it again and stop it altogether. After only 4 days off it, I realize the depression I have been experiencing in the last few months could possibly have been the omeprazole as well. I am starting to feel like 'my old self again.' I would rather try a bland diet and drink just water than go back on this medication. I’ll see how that goes!"

• Cee...
• March 23, 2021

For GERD "I've had GERD for several years. Recently worse with weight gain during COVID. I took this for 14 days, so depressed and no energy to do much of anything. It does control the acid, BUT I can't stand the depression. Started again, but 2 days later, so depressed. Have to only use Tums right before bed, which seem to work, I guess, the rest of my life. Thoughts?"

• ENP...
• Taken for less than 1 month
• May 21, 2022

For GERD "I have been on a very low dose of antidepressants, 10 mg, for 3 months and feel good, however, they make my stomach burn. My doctor prescribed omeprazole, 20 mg, and I have been taking it for 2 days. My mum always screams at me for googling side effects, but thank God I do because the side effects on the leaflet of omeprazole do not say brain fog, anxiety, or depression. I am thankful to you all for your reviews because without reading them I wouldn’t have stopped at just 2. Wish you all the best."

• Enn...
• Taken for less than 1 month
• April 25, 2021

For GERD "This drug did not help my mom. What they gave her was depression and anxiety. She doesn’t sleep at all. She lost a lot of weight. She says all her muscles ache. Before taking them, she was outgoing, and now she stays in bed all day. I don’t know what to do. Looking at the other reviews, I see that many of you who took this drug have experienced similar effects. How can you overcome this terrible drug? Please help."