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Olanzapine for Depression User Reviews (Page 2)

Brand names: Zyprexa, Zyprexa Zydis, Zyprexa Relprevv, Zyprexa Intramuscular

Reviews for Olanzapine

Commonly mentioned side effects
  • Anonymous
  • January 16, 2011

Olanzapine "I took Klonopin and Paxil for 15 years to treat my anxiety disorder. I had to detox from the Klonopin this past spring. I got off the Klonopin and switched my Paxil to Lexapro (sex side effect issue). I am also a recovering alcoholic. My doctor did not want me on Benzo's anymore (says it increased alcohol cravings). I stayed on Lexapro only for 9 months, but my anxiety came back strong on just the Lexapro alone. I almost resorted to taking Xanax before I switched doctors. My new doc gave Zyprexa a chance. I am on my 7th day and I haven't felt this 'normal' in 5 years. I take 5mgs at night and it has ended the 'chatter' in my head, and removed my anxiety. Great medicine so far."

10 / 10
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  • dpo...
  • Taken for less than 1 month
  • June 16, 2023

Olanzapine "This drug ruined my life. I was experiencing a mild depression and wanted a 'buffer' before I started my new career in Atlanta, GA, at Emory Hospital. The night I took Zyprexa, I slept 12+ hours. I immediately started to gain weight - my lean muscle tissue was replaced by adipose tissue. I developed gynecomastia (man boobs). I was tired and irritable all day due to Zyprexa's anti-dopaminergic effects. In a frenzied effort to heal my body, I spent so much money on organic foods because no matter how healthy I ate and how much I exercised, I kept gaining weight. This drug was a nightmare and took me about 3 months of absolute terror to heal from."

1 / 10
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28 Report
  • Too...
  • September 13, 2019

"I have been on many different antidepressants for depression and for insomnia/PTSD. So I started on Prozac 20 mg a day. I had relatively no side effects! I started sleeping a bit better and wasn't so unhappy. But I still wasn't feeling like myself. So, I read up on add-on type products and found olanzapine as a great combo with Prozac. I got that prescribed but sat on it for a while because I also read all the horrible side effects and got scared. But after a month, still not feeling like myself, I decided to try a very small dose. (I read you could split the pill safely), that way it would be easier to get off of it. So, I cut a 5 mg pill into eight pieces... so 0.625 mg - a couple of hours before bed. I slept better than I had in years! I've been taking it for about 2 weeks. I again, lucky, have had zero side effects. I feel AMAZINGLY happy!! I am going to stay on the super low dose. I hope this helps someone, maybe you can ask your MD about taking a smaller dose to get the good effects and not the bad ones."

10 / 10
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Frequently asked questions

  • jog...
  • November 2, 2011

Olanzapine "I have taken Zyprexa 2.5 with Zoloft for years and couldn't function without this combination. It was prescribed because the Zoloft just didn't take care of the insomnia and mood swings. Zyprexa 2.5 has been a Godsend."

10 / 10
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  • Gam...
  • Taken for 1 to 6 months
  • February 20, 2020

"I am from Kenya, that is in East Africa. I was diagnosed with depression by my doctor and put on Deprex 10 mg, which is also a brand name for olanzapine. I took it for about 28 days, which went well. I got good sleep, but after that, it was a nightmare. I was getting brain fog. I tried to quit it, but the withdrawals were crazy. I couldn't sleep at night, restlessness was another issue. So, I self-lowered to 5 mg. I am not having a normal sleep, waking up a couple of times at night. Last night, I took 2.5 mg. I am really trying to get off this garbage by tapering because the withdrawal is unbearable. DON'T TAKE THIS DRUG IF YOU LOVE YOURSELF AND YOUR LIFE."

1 / 10
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  • Anonymous
  • February 13, 2012

Olanzapine "This medication is a great sedative, if that's what you're looking for. It's not euphoric, it just makes you sleepy. But it caused me to gain over 40 pounds in less than 2 months. I now get depressed just looking in the mirror. My doctor says it just makes you hungry, not gain weight, but the amount of weight I gained in such a short time is unnatural!"

7 / 10
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  • Aki...
  • March 5, 2023

"Olanzapine saved my life... wait. Just kidding. I hate this drug. It stole my personality and way of feeling myself. After withdrawing, I have abnormal headaches, no motivation, and depressed to some extent. Thankfully I don't have insomnia, but I have realized I am sleeping lighter than before. This is poison. Don't take it."

1 / 10
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  • Anonymous
  • October 28, 2013

"Zyprexa has been a wonder drug for me. After 10 years of serious depression and Bipolar 1 disorder and several different meds, this medication saved my life. After 9 hospitalizations and 2 suicide attempts, I was put on 10 mg of Zyprexa and have been stable for 3 years. This medicine has been a Godsend!"

10 / 10
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97 Report
  • Ren...
  • October 22, 2013

Olanzapine "I have been on this medication for about 3 weeks now. I wake up hungry, drenched in sweat, and have also gained 15 pounds. I'm thinking about getting off this medication. I have also had crying spells, irritability, and mood swings, then some other days I have felt fine. It's weird. I'm going to give it a few more weeks, and if nothing improves as far as my moods, I will get off of it."

2 / 10
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  • rb1...
  • Taken for 1 to 6 months
  • April 9, 2016

Olanzapine "Was on Zyprexa from Mar 2015 till Aug 2015. At first, it seemed like it was mellowing me out a bit, and I could sleep through the whole night, which was an improvement. After a few months, I noticed my depression was getting much worse. Came off the drug cold turkey, and went through one of the most serious withdrawals one could face. Depression, severe anxiety, PTSD, night terrors took over. To this day Apr 2016, I have still not returned to the way I was before I started taking this horrible drug. Depression and anxiety are still bad, not as bad as 6 months ago, but still worse than when I first started taking it. I'm convinced this drug can cause permanent brain damage."

2 / 10
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  • Lil...
  • Taken for 1 to 6 months
  • September 30, 2018

Olanzapine "I have never been a fan of antidepressants as I feel they are a bandaid for underlying problems. I am starting to think differently. My doctor put me on 2.5 mg along with 0.5 Xanax. After years of feeling depressed and hopeless, I now have more energy, sleep well at night, waking up feeling great. I have also gained weight, which I needed to do. I give Zyprexa 10 stars."

8 / 10
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67 Report
  • che...
  • February 1, 2011

Olanzapine "Found this medication very effective in my withdrawals from both alcohol and weed. It stops my racing thoughts and keeps me calm. However, it does somewhat make you zombie-like and unable to feel emotions."

8 / 10
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  • smo...
  • Taken for 1 to 2 years
  • December 5, 2024

Olanzapine "I have taken 5 mg Zyprexa with 40 mg of Prozac for 2 years. I use it for BPD and anorexia. It has made me gain 20 kg (42 lb), which I desperately needed. It has really helped with my mood and my energy. It does make me snore loudly, which is difficult for my partner, but they see such an improvement in my body and mind on them that we will just sleep in different rooms when I snore! Zyprexa may not be for everyone, but for me, it saved my life and gave me such comfort and calmness in my mind."

10 / 10
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  • hih...
  • October 15, 2012

Olanzapine "I take 5 mg of Zyprexa daily. I'm almost the entire day sleepy and have the feeling of doing nothing. I cannot worry because I have to sleep for about 15 hours daily. But I have tried everything out there, and this is the best at this moment."

6 / 10
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  • Wor...
  • Taken for less than 1 month
  • February 26, 2020

"Olanzapine is the worst drug ever. Made my depression even more severe, made me feel numb and like a vegetable. And the withdrawal period is the worst, even after taking it only for 4 days! Glad it's over."

1 / 10
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  • Vic...
  • Taken for 2 to 5 years
  • April 17, 2023

"Take it now if you finally want to beat depression! Don't be silly and take advantage of the fact that we don’t live in medieval times anymore and we have science and pharmacological intervention to treat things once thought incurable. The opportunity to dig yourself out of the bottomless pit you’re in right now is in your hands, so make the right choice. With mental illness, decision-making can be impaired, so listen to the guidance of the people around you and especially professionals. Don't be scared (like I was)."

10 / 10
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  • Nat...
  • Taken for less than 1 month
  • May 16, 2019

"Olanzapine made me feel terrible. I was prescribed it for a depressive episode and quickly found (within a few days) that I felt worse. I was in a constant state of feeling despair, panic, and anxious as a result of it. I then went back to a different doctor who immediately withdrew this drug (luckily it had only been a few days). I was then prescribed Escitalopram, which I used for a couple of months. Olanzapine is an extremely strong drug that was wholly inappropriate to my treatment."

1 / 10
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  • joy...
  • Taken for 2 to 5 years
  • February 18, 2015

"This medication has been a lifesaver for me. After suffering severe situational depression and three serious suicide attempts, I was put on 5 mg. It took away anxiety. I'm also on venlafaxine, which just wasn't enough for me. I have not put on weight and eat healthy. I have tried to come off, and anxiety and low mood came back."

10 / 10
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  • Now...
  • August 6, 2021

Olanzapine "I have never written a review, but what I am experiencing is something I do not wish on anyone. Please listen to what I am saying before it is too late for you. The first thing I want to point out is that they say this drug is not addictive. I will tell you that is the biggest crock I have ever heard. It is beyond addicting. You cannot just stop it. The nausea, vomiting, upset stomach, depression, mania, insomnia, desire to just die to get this over with, shaking, you feel cold and hot at the same time. The withdrawals are unbearable, so naturally people keep taking it. The only solution I see to this is to find a rehab for this and have professionals help me through this. I should have never been placed on this drug to begin with. I needed to gain weight. But to give me one of the strongest antipsychotics for that is criminal. Sure, I gained 40 pounds, but I have no life. No desire to live. No focus. No motivation. Nothing. If you are not psychotic, do not take this poison."

1 / 10
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  • Gem...
  • January 4, 2023

Olanzapine "If you want to lose your good emotions and connections to the world, then take this poison. I'm not sure why you would want that, though. You'll get obese on this crud, horrible, torturous withdrawals that will last years. Who in their right mind would invent something like this? Only a psychopath."

1 / 10
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23 Report
  • cma...
  • Taken for less than 1 month
  • July 23, 2017

Olanzapine "I was only on Zyprexa for 10 days, but it made me so tired I couldn't even function. All I wanted to do was sleep all day. And it made my depression worse. I was so depressed by that 10th day that I almost quit my job because I just felt like I couldn't handle any stress at all. So glad I stopped taking this drug."

1 / 10
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53 Report
  • rui...
  • Taken for 5 to 10 years
  • January 22, 2023

Olanzapine "I was prescribed Zyprexa for anxiety. Over the 5 years I took it, I gained 100 lbs and have now developed secondary dystonia, tardive dyskinesia. I have changed doctors, who immediately took me off it. I would not recommend this medication."

1 / 10
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19 Report
  • bee...
  • November 4, 2015

Olanzapine "Sure, this med can keep depression at bay, but it can also cause some really horrible side effects. After being on this med for 1 year, I went from being a healthy 170 lbs (women's size 12) to 250 lbs (size 20). It made me so lethargic and tired. I would sleep for 14 hours a day and still be dragging out of bed. About 2 months ago was the final straw. I got blood work done by my GP, and my triglycerides were through the roof, as well as elevated blood sugar. The doc was ready to put me on meds for diabetes! I'm only 25, and I just wanted my health back, so last week I went to a new doc who got me off this horrible stuff. I feel like a new person without this toxic med in my body. Now, I'm on Viibryd."

2 / 10
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  • Haz...
  • Taken for less than 1 month
  • January 4, 2022

Olanzapine "After being prescribed Zyprexa for depression, I immediately went to Google for reviews, they were horrible! In all honesty, it works for me, yet I'm on a small dose of 5 mg at bedtime. I can tell a huge difference in my mood. I can't speak for anyone else, but I hope to continue taking Zyprexa until hopefully I no longer need it."

10 / 10
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26 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • December 2, 2020

Olanzapine "Zyprexa worked pretty well for me for a good year. It helped with my OCD and anxiety, and it made me feel the happiest and most normal I have ever felt. It helped with intrusive thoughts and obsessive thinking. I hope it helps again when I start it back up."

10 / 10
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30 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.