Nystatin and Sore Tongue: What Users Say

• Chr...
• Taken for less than 1 month
• May 13, 2020

For Oral Thrush "Laryngitis for 6 weeks that gets worse as the day goes on to the point that by the end of the day it physically hurts to talk. But with COVID, I was scared to see a doctor. No other COVID symptoms. Finally saw a doctor, no COVID, no strep. 2 weeks later, no improvement. Tested for COVID again, negative again but this time, doctor diagnosed thrush (no idea how you get that???) and gives me nystatin 4 times a day. Day 2, voice sounds better, lump feeling in throat almost feels gone. I can talk, throat not so painful but tongue feels like I ate a bag of sour candy. When I take the nystatin, it tingles on my tongue - is this normal? Should my tongue hurt like this afterwards as well?"

• Awa...
• Taken for less than 1 month
• September 13, 2020

For Oral Thrush "On 2nd bottle of Nystatin for oral thrush at back of tongue, it seemed to work initially, but symptoms are getting worse now. I'm struggling with bad breath, metallic taste, sore tongue, and loss of appetite. I guess I have to go back to the GP."

• Inv...
• Taken for less than 1 month
• June 15, 2021

For Oral Thrush "So far, I’ve been on Nystatin “mouthwash” for 4 days, and it’s been miserable. My mouth is so dry it’s uncomfortable, and my tongue feels raw and dry. Nothing is helping, so I’m beginning to wonder if this side effect isn’t from overusing. My thrush cleared in 2 days with this, so by all means, it’s amazing for oral thrush, but I’m beginning to wonder if it’s not just burning my tongue since there’s no longer thrush in my mouth to fight. That rubber banana flavor is quite literally vomit-worthy. My tummy has been making LOUD noises, and like others, I’ve had a few strange heart palpitations after taking it, but it DID work (4ml 4x daily) to clear the icky. I cannot wait to be done with it."

• Mob...
• Taken for 1 to 6 months
• October 14, 2020

For Oral Thrush "I'm on my second bottle. Thrush is still there. Tongue feels numb, and I was told to swallow the nystatin after swirling it around in my mouth. Ever since then, I feel nauseous all the time. So, definitely not working for me."

• Anonymous
• August 2, 2022

For Oral Thrush "I was given amoxicillin for a dental infection. On the second day, I got thrush in my throat, and one side of my tongue was sore and had little blisters. The ER gave me nystatin. On the second day, my throat got better, but my tongue is sore, and I have a metallic taste. It's the sixth day, I quit it."