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Singulair and Mood Swings: What Users Say

Mood swings: mentioned by 8 users (3.6%)

Based on user experiences from 221 Singulair reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 12.2%
depression 10.9%
irritability 8.6%
anger 7.2%
headaches 6.3%
shortness of breath 5.4%
insomnia 4.1%
suicidal thoughts 4.1%
tiredness 4.1%
mood swings 3.6%

Reviews for Singulair

Commonly mentioned side effects
  • Kdu...
  • Taken for less than 1 month
  • March 31, 2015

For Asthma "Started Singulair approximately 1 week ago. I will say it's an asthma miracle, but the side effects are unreal. I had extreme irritability (out of character for me), severe fatigue when normally active, mood changes, depression, anxiety. I wish doctors would really explain this to new users. Thanks to all of you who reviewed this medicine and gave me insight on what was going on, that's the reason for my post too."

1 / 10
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  • Sco...
  • Taken for less than 1 month
  • June 14, 2018

For Allergic Rhinitis "This drug is not for everyone. I took it for just three days and got very depressed, even to the point of having really dark thoughts, had a constant headache, an upset stomach, deep soreness in my teeth, mood swings, and irritability. However, it did help my allergies. Be very conscious of how you feel when you try this drug."

2 / 10
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83 Report
  • MM ...
  • Taken for 5 to 10 years
  • October 10, 2018

For Allergic Rhinitis "I am a parent of two children. Both children took Singulair for allergies. Both children had issues while taking Singulair and experienced withdrawal effects once I stopped the medication. My daughter developed tics, tremors, anger, rage, OCD, anxiety, mood swings, and agitation, to name a few side effects. My son developed frequent urination, muscle issues, joint pain, and sadness. Both my children developed a hypersensitivity to all artificial sweeteners, dyes, and all emulsifiers/preservatives as the inactive ingredients are made up of most of these items. Their hypersensitivity to artificial sweeteners, dyes, and emulsifiers/preservatives still continues even though they stopped the medicine."

1 / 10
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82 Report

See also:

Frequently asked questions

  • Anonymous
  • January 6, 2012

For Allergic Rhinitis "Yes, I think this medicine works in treating allergic rhinitis, but after not being able to sleep at all the night I took it and being extremely agitated with mood swings tapering off into the next day after a full night's sleep, I will take it no more. I think each person needs to weigh the benefits versus the side effects for them. Everyone is, of course, different and each responds in their own way to all of these medicines. Just monitor your reaction to the drug closely if you do decide to use it and make the right decision for you to continue it or not."

3 / 10
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63 Report
  • Cra...
  • January 23, 2013

For Asthma "I found it really helped my asthma and has made a big difference in the quality of my life. However, what I would say is that it did cause mood changes with me; these were very noticeable for the first few weeks. It felt like I had drunk 10 tins of Red Bull. I was very confrontational; this subsided greatly, though, and in some ways made me more confident. I never take the tablets in the morning, though, always at night, or I will kick off for the slightest thing, which is totally out of character for me."

7 / 10
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54 Report

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  • Em0...
  • Taken for 6 months to 1 year
  • September 5, 2017

For Asthma, Maintenance "Singulair has been a godsend to help control my daily asthma symptoms due to allergenic/mold triggers. I haven't noticed it make a difference with exercise or smoke triggers, but it definitely helps reduce frequency/severity of asthma symptoms in general. If I take a few days to pick up my prescription, I can absolutely feel a difference in my lung health. I've been waiting the past few days to get the entire prescription renewed with my doctor, and I had a nighttime attack last night for the first time since I started taking the medicine (it's been six days since I last took it). I have not experienced any mood changes even though I already had diagnosed anxiety when I started the medication or any other adverse side effects."

9 / 10
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36 Report
  • pre...
  • Taken for less than 1 month
  • January 21, 2013

For Asthma "Very good for asthma and allergies, but my mood changed for the worse. I woke up angry for no reason and very irritable. Made my anxiety worse too. I stopped it."

3 / 10
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72 Report
  • Anonymous
  • November 9, 2009

For Asthma "Great for the asthma, bad for the mood. Cleared up the runny nose and the cough. Started to make me think of some very bad things. I was getting angry with everyone over relatively anything."

1 / 10
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55 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.