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Singulair and Headaches: What Users Say

Headaches: mentioned by 14 users (6.3%)

Based on user experiences from 221 Singulair reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 12.2%
depression 10.9%
irritability 8.6%
anger 7.2%
headaches 6.3%
shortness of breath 5.4%
insomnia 4.1%
suicidal thoughts 4.1%
tiredness 4.1%
mood swings 3.6%

Reviews for Singulair

Commonly mentioned side effects
  • Dee...
  • Taken for 2 to 5 years
  • August 3, 2019

For Allergic Rhinitis "I have been taking this medication for a few years to treat allergies. At first, I would get headaches, but they went away after a few months of use. I do not have anxiety issues with the use of this drug. This drug is a lifesaver for my allergy symptoms, and I will continue to use this drug."

9 / 10
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  • Sco...
  • Taken for less than 1 month
  • June 14, 2018

For Allergic Rhinitis "This drug is not for everyone. I took it for just three days and got very depressed, even to the point of having really dark thoughts, had a constant headache, an upset stomach, deep soreness in my teeth, mood swings, and irritability. However, it did help my allergies. Be very conscious of how you feel when you try this drug."

2 / 10
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83 Report
  • rav...
  • August 2, 2013

For Allergic Rhinitis "Started taking Singulair with Zyrtec 3 weeks ago for a severe allergy I developed to my 3 pet rabbits. No side effects to speak of (I did have a headache one day, but I don't think it's related) and today I held one of my bunnies for the first time in 6 months without allergy symptoms. Now I don't have to get rid of some beloved family members!"

10 / 10
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107 Report

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Frequently asked questions

  • ind...
  • December 14, 2011

For Allergic Rhinitis "This product seemed to help with my allergies somewhat, but after several months of suffering a large increase in migraine headaches, my neurologist and I decided to stop using Singulair. The constant tightness in my head was gone within a week. It seems that this is a common side effect of this medicine. Migraine sufferers beware!"

5 / 10
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65 Report
  • Cas...
  • April 7, 2015

For Allergic Rhinitis "Been suffering from ETD for about two years. I've been on Singulair for about 4 months, and it has dramatically improved my symptoms, no more ear crackling. Occasional tiredness and headache, but it's tolerable. It has helped me tremendously."

9 / 10
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49 Report

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  • Anonymous
  • Taken for 1 to 6 months
  • October 16, 2012

For Asthma, Maintenance "Completely effective for asthma maintenance, side effects - insomnia, weird dreams when able to sleep, headaches, and nosebleeds. Only took for 4 weeks. Unfortunately, now after stopping it, have limited lifestyle (Singulair gave me back a life)."

6 / 10
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48 Report
  • Min...
  • May 14, 2017

For Allergic Rhinitis "I have severe allergies to tree pollen. I took my first dose of this, and within an hour and a half, I had severe shaking, chills, and tingling tongue. Extreme headache. Sitting here wondering whether I should head to the ER."

2 / 10
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25 Report
  • Hid...
  • Taken for 1 to 2 years
  • May 26, 2023

For Asthma "I was on this for a year with no improvement in my asthma. Two days after getting off of it, I began to have horrific withdrawals, including severe headaches, exhaustion, irritability, weepiness, depression, lightning shocks throughout my body, severe body aches, and inability to sleep. The worst seems to have occurred for 48 hours straight, with no signs of fever or sore throat to indicate flu. After seeing others in forums, it seems to be this medication."

1 / 10
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7 Report
  • Fai...
  • Taken for less than 1 month
  • January 5, 2021

For Allergic Rhinitis "Singulair is horrible!! It made my face swell, and I had extreme flushing. It made me itch all over! Gave me bad diarrhea and headaches. I would not recommend this drug to anyone!! DO NOT TAKE THIS STUFF, PLZ!!!"

1 / 10
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15 Report
  • IL5...
  • Taken for less than 1 month
  • October 15, 2022

For Allergic Rhinitis "I was prescribed this medication after a doctor visit yesterday for an asthma flare-up and allergic rhinitis. It is to be taken 1 tablet every evening. I was not informed of the 'black box warning' verbally by my doctor or pharmacist but did read the pamphlet insert given at RX pickup. I was a bit concerned but read mixed reviews on this site and thought I would give it a try. I will not be taking another dose. After an hour of ingestion, I started feeling slight swelling in the back of my throat and an increased heart rate. It wasn't severe but definitely noticeable. Two hours passed, and I was getting a headache, so I went to bed and had insomnia. I massaged my scalp, relieved some headache pressure, and finally fell asleep. The medication did seem to dry up the post-nasal drip, but I awoke with my face looking as if I had spent the day in the sun. These side effects are not worth the long list of 'possible' short-term and long-term side effects it has on the body. I will seek natural remedies for relief."

2 / 10
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6 Report
  • SiW...
  • Taken for less than 1 month
  • February 4, 2021

For Allergic Rhinitis "I started taking this to help with long COVID-induced asthma/rhinitis (suffered from asthma as a child, but COVID exacerbated it) in addition to steroid inhalers. In terms of the asthma/rhinitis, it worked brilliantly. However, after about 10 days (10 mg per day taken in the evening), I developed severe dizziness/vertigo and headaches. Had to stop taking it, as I simply couldn't function."

3 / 10
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3 Report
  • Anonymous
  • August 1, 2010

For Bronchospasm Prophylaxis "I have really bad asthma, and nothing seemed to help. I recently started taking Singulair, and my asthma has improved unbelievably. No more wheezing and severe headaches. I feel like a new person."

10 / 10
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70 Report
  • JJ1...
  • May 7, 2011

For Asthma "It gives me headaches."

4 / 10
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21 Report
  • Mam...
  • Taken for 6 months to 1 year
  • January 11, 2021

For Asthma "Singulair helps long term to control asthma. It does affect moods. I take it at bedtime, sometimes, it makes me have insomnia. I’m not sure about headaches, as I take inhalers that could cause that."

9 / 10
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4 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.