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User Reviews for Depo-Medrol

Depo-Medrol has an average rating of 6.8 out of 10 from a total of 13 ratings on Drugs.com. 60% of those users who reviewed Depo-Medrol reported a positive effect, while 40% reported a negative effect.

Condition Avg. Rating Reviews Compare
Inflammatory Conditions  
5.3
8 reviews 120 medications
Osteoarthritis  
10.0
4 reviews 351 medications
Rheumatoid Arthritis  
9.0
1 reviews 360 medications
Summary of Depo-Medrol reviews 6.8 13 reviews

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Depo-Medrol

misslottie · Taken for 10 years or more February 9, 2020

For Osteoarthritis: “Years ago when I had bronchitis my family doc gave me injection of depo-medrol and it not only fixed my lungs it fixed the pains everywhere in my back and hip. Fast forward years later my family doc retired and I had a hard time to find someone to give the injection. Finally a pain clinic will give it but I need it more than every 3 months. Its intramuscular injection. I have severe osteoarthritis now and take calcium and magnesium supplements . I am in severe pain 30 days after the injection and am bed ridden until I can get the injection again. I get low dose opiates they do not touch the pain and doc wont up the mg dose and I am afraid to take Meloxicam and Diclofenac the RX NSAIDS.”

10 / 10
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Crazylady October 26, 2019

For Inflammatory Conditions: “I have Autoimmune disorder, Spinal stenosis, Arthritis. I was given one injection in my back of Depo-Medrol and it hasn't worked at all! Although I did have many of the side effects after the first week. I have been on the shot for 3 weeks now. My eyes are burning, blurred, I have headaches, sharp pain in my legs, sharp pain in my temples, and more.”

1 / 10
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hags · Taken for 1 to 6 months April 20, 2019

For Inflammatory Conditions: “Got a epidural steroid injection (ESI) in T5/6 and felt a sharp pain. Procedure went well after that. One month later strange pains in spine started. Never told of any risks or ESI. Now in HORRIBLE PAIN in low back, neck and mid back 4 months later. MRI shows nothing and doctors think I am crazy. Trust me- I am not crazy. This stuff is poison. I think I may be in for a life of misery.”

1 / 10
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Frequently asked questions

Anonymous October 9, 2011

For Inflammatory Conditions: “I have rheumatoid arthritis and fibromyalgia. Everything builds to climax with extensive swelling and pain that goes from skull to toe. Nothing brings relief even though I am on a constant dosage of Predisone. Only relief is from an injection of Depo Mederol from my Rheumatologist. Relief occurs in 1/2 a day. At that time life is worth living again and lasts for about 3 weeks. I hate it all but this bit of relief is "a temporary heaven on earth." Pray for me and people like me!”

9 / 10
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Fibro- flare · Taken for 2 to 5 years February 9, 2015

For Inflammatory Conditions: “My primary doc actually gave me a shot of this when I threw my back out. I never felt better. I went back to him and told him not only did it help with my back, but with may fibromyalgia! My rheumatologist had given me all sorts of pills to try and I felt like like a science experiment! I usually get it 1-2 times a year. I stretch it out until I know I can't take it anymore and my body tells me- "help"- it has done me wonders! I can get back on my feet and be me within a day or 2 depending on how bad I am. No more docs pushing pills down my throat or telling me it's all in my head, & I can get outta bed when the alarm goes off- not hitting snooze and for 2 hours and Practically in tears! I know my body N it works for me! Good luck!”

9 / 10
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Aryl September 28, 2013

For Inflammatory Conditions: “My hair is falling out. It's so hard to lose weight. I feel mentally a little off like constant irritation. I also feel a little lethargic. When I first got the shots I felt jittery for days. I'm having blurry vision. ”

1 / 10
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pazza · Taken for 1 to 6 months January 23, 2013

For Inflammatory Conditions: “I had severe soft tissue damage. The inflammation would not subside and was creating other problems as the inflammation was choking nerves. I did a series of 11 injections in the area (12"x12" area) over approximately 8 weeks. It worked. It took about 2 months to feel full effects. My side effects included minimal pain at the injection point for a day or 2 after each injection and major upper body sweating. Thank God for this medicine as it was the only thing that worked to minimize the inflammation.”

10 / 10
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More FAQ

Jolly Green Giant July 17, 2013

For Osteoarthritis: “I get an injection (40) in my hip and knee every three months. Has been a great relief for over 5 years. I am almost 68 years old. Have told other seniors of this great injection to avoid or delay knee and hip replacement and pain relief.”

10 / 10
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Natawol · Taken for less than 1 month September 26, 2015

For Rheumatoid Arthritis: “Having had rheumatoid arthritis with secondary sjorgrens and Raynaud's for twenty odd years I have tried so many combinations of medication. The best result was Methotrexate but unfortunately after a bout of pneumonia this was stopped. I was at my wits end and lost interest in everything.....even the news that I was going to be a grandma! My rheumatologist, seeing my distress gave me the injection and its like a new world! I have the odd 'ouch' but I can now sleep, my memory is back, I can smile and mean it. Don't know how long it will last but for me its been a bit of a lifesaver.”

9 / 10
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1111sallyg January 22, 2013

For Osteoarthritis: “Had injections in both knees today. Aching a little but severe pain easing. I have been advised by specialist as long as shots work to avoid having knee replacements, as that is a long time to recoup. I hate reading all the side effects of Depo Medrol, too. The dosage is very minimal I've been told. Today's injection was my first since July!”

10 / 10
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jc479 · Taken for less than 1 month August 16, 2018

“I was injected with 160mg of depo medrol after going in for allergies. I felt fine for the first couple hours but then my heart rate started fluctuating between 60-249 BPM. I felt really dizzy, and had chest pain for about two days. I’m now on my 6th day after being on the shot and I’ve been having really bad neck pain and stiff / sore muscle pains although I’m not sure if it’s from the shot.”

1 / 10
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jj April 24, 2018

For Inflammatory Conditions: “Depo medrol is a nightmare drug which makes my skin extremely dry, flakey, and peeling. This drug has messed up my bowels causing extreme gas and bloating plus sticky stools plus I have to use the bathroom all day some days and my anus will itch. I suggested maybe I have worms but three stool samples say I don't. I feel chronically tired and hurt everywhere and now I have daily headaches. This drug makes me think slow and feel dumb. So depressing. Been to a few doctors and all they care about is a colostomy which I feel is not the antidote for these bad side effects I've had for well over a year. I complained about these side effects after I was first given these injections and the doctor turned a blind eye to them and kept giving me depo medrol for over a year. I wonder if the doctor is keeping me sick to make money off of me.”

1 / 10
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giojazz September 15, 2016

“After moving into an old apartment in Florida, I developed a severe skin rash which I attribute to mold in the walls. The rash was from my neck to my ankles. Itched/burned beyond belief. Went to Urgent Care and received an injection of this miracle drug which is the only thing that provided relief. I had no side effects at all. Just gratitude to be taken out of my misery if only temporarily.”

9 / 10
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Anonymous · Taken for less than 1 month November 18, 2012

For Inflammatory Conditions: “A little trouble sleeping yet the inflammation simply disappears!”

10 / 10
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K. James February 2, 2018

For Osteoarthritis: “I ended up with arachnoiditis after a Epidural spinal injection(ESI). This is NOT FDA approved for the back but your PM doc won’t tell you this. It ruined my life!”

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Anonymous · Taken for less than 1 month March 25, 2017

“Had injected into spine via epidural steroid injection RUINED LIFE!”

1 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.