Skip to Content

Depo-Medrol (methylprednisolone) Drug Interactions

A total of 778 drugs are known to interact with Depo-Medrol (methylprednisolone).

  • 95 major drug interactions
  • 602 moderate drug interactions
  • 81 minor drug interactions

Show all medications in the database that may interact with Depo-Medrol (methylprednisolone).

Check for interactions

Type in a drug name to check for interactions with Depo-Medrol (methylprednisolone).

Most frequently checked interactions

View interaction reports for Depo-Medrol (methylprednisolone) and the medicines listed below.

  • Aspirin Low Strength (aspirin)
  • cetirizine (Zyrtec, Aller-Tec, Children's Zyrtec, Equate Allergy Relief, Children's Allergy Relief, Aller-Tec Children's, PediaCare Children's 24-Hour Allergy, All Day Allergy Children's, All Day Allergy, Zyrtec Hives, Alleroff)
  • cyclobenzaprine (Flexeril, Fexmid, Amrix, Comfort Pac with Cyclobenzaprine)
  • Cymbalta (duloxetine)
  • dexamethasone (Decadron, Dexamethasone Intensol, Dexasone, TaperDex, Decadron Phosphate, Injectable, Hexadrol, Dalalone, Baycadron, Dexacort Phosphate in Respihaler, De-Sone LA, Dexone LA, Medidex, Dexpak Taperpak, Zonacort, LoCort, Adrenocot LA, Dalalone DP, Dalalone LA, HiDex, Decaject, Decaject LA, Zema Pak, Dxevo, Decadron-LA, Solurex LA, Dexacen-4, Solurex, Adrenocot, Dexacort-LA, Dexasone LA, Dexone, Primethasone, ZoDex, Dexacorten, Medidex LA)
  • Flexeril (cyclobenzaprine)
  • folic acid (Folvite, Folacin-800, FA-8, FaLessa)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Motrin IB, Proprinal, Advil Children's, Caldolor, Children's Motrin, Childrens Ibuprofen Berry, Motrin Childrens, Rufen, Ibuprofen PMR, Ibu-8, Motrin Pediatric, Menadol, Nuprin, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Advil Migraine, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, NeoProfen, Ibu-Tab, Genpril, Haltran, IBU-200, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • lidocaine (Xylocaine-MPF, Xylocaine Dental Cartridges, Nervocaine, UAD Caine, Xylocaine HCl, Lidoject 1, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Truxacaine, Anestacaine, DentiPatch)
  • Lipitor (atorvastatin)
  • Lyrica (pregabalin)
  • Marcaine (bupivacaine)
  • meloxicam (Mobic, Vivlodex, Qmiiz ODT)
  • Nexium (esomeprazole)
  • Norco (acetaminophen / hydrocodone)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • pantoprazole (Protonix, Protonix IV)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Meticorten, Sterapred DS, Liquid Pred, Orasone, Prednicen-M)
  • Solu-Medrol (methylprednisolone)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Zydol, Tramahexal, Ryzolt, Tramal SR, ConZip, Larapam SR, GenRx Tramadol, Tramedo, Zamadol, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)

Depo-Medrol (methylprednisolone) alcohol/food interactions

There are 3 alcohol/food interactions with Depo-Medrol (methylprednisolone)

Depo-Medrol (methylprednisolone) disease interactions

There are 24 disease interactions with Depo-Medrol (methylprednisolone) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide