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Depo-Medrol (methylprednisolone) Drug Interactions

A total of 774 drugs are known to interact with Depo-Medrol (methylprednisolone).

  • 94 major drug interactions
  • 600 moderate drug interactions
  • 80 minor drug interactions

Show all medications in the database that may interact with Depo-Medrol (methylprednisolone).

Check for interactions

Type in a drug name to check for interactions with Depo-Medrol (methylprednisolone).

Most frequently checked interactions

View interaction reports for Depo-Medrol (methylprednisolone) and the medicines listed below.

  • Aspirin Low Strength (aspirin)
  • cetirizine (Zyrtec, Equate Allergy Relief, Aller-Tec, All Day Allergy, All Day Allergy Children's, Aller-Tec Children's, PediaCare Children's 24-Hour Allergy, Children's Allergy Relief, Zyrtec Hives, Children's Zyrtec, Alleroff)
  • cyclobenzaprine (Flexeril, Amrix, Fexmid, Comfort Pac with Cyclobenzaprine)
  • Cymbalta (duloxetine)
  • dexamethasone (Decadron, Dexamethasone Intensol, Decadron Phosphate, Injectable, Hexadrol, Dexasone, TaperDex, Baycadron, Dexacort Phosphate in Respihaler, Dexone, Dexone LA, ZoDex, Dexpak Taperpak, Zonacort, LoCort, Adrenocot LA, Dalalone, Dalalone DP, Dalalone LA, HiDex, Decaject, Decaject LA, Zema Pak, Decadron-LA, Solurex LA, Dexacen-4, Solurex, Adrenocot, De-Sone LA, Dexacort-LA, Dexasone LA, Primethasone, Dexacorten, Medidex, Medidex LA)
  • Flexeril (cyclobenzaprine)
  • folic acid (Folvite, FA-8, Folacin-800, FaLessa)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • ibuprofen (Advil, Motrin, IBU, Children's Motrin, Proprinal, Advil Liqui-Gels, Ibu-8, Motrin IB, Motrin Childrens, Rufen, Childrens Ibuprofen Berry, IBU-200, Ibuprofen PMR, Advil Migraine, Ibu-Tab, Genpril, Menadol, Advil Children's, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Addaprin, Motrin Infant Drops, NeoProfen, Caldolor, Motrin Pediatric, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • Lexapro (escitalopram)
  • lidocaine (Xylocaine-MPF, Xylocaine HCl, Lidoject 1, Xylocaine Dental Cartridges, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Nervocaine, Truxacaine, UAD Caine, Anestacaine, DentiPatch)
  • Lipitor (atorvastatin)
  • Marcaine (bupivacaine)
  • meloxicam (Mobic, Vivlodex, Qmiiz ODT)
  • Nexium (esomeprazole)
  • Norco (acetaminophen / hydrocodone)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • pantoprazole (Protonix, Protonix IV)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Sterapred DS, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • Solu-Medrol (methylprednisolone)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, ConZip, Zydol, Tramal SR, GenRx Tramadol, Zamadol, Ryzolt, Tramedo, Larapam SR, Tramahexal SR, Tramahexal, Zydol XL, Rybix ODT, Ultram ODT)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)

Depo-Medrol (methylprednisolone) alcohol/food interactions

There are 3 alcohol/food interactions with Depo-Medrol (methylprednisolone)

Depo-Medrol (methylprednisolone) disease interactions

There are 24 disease interactions with Depo-Medrol (methylprednisolone) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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