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Medroxyprogesterone and Headaches: What Users Say (Page 5)

Brand names: Provera, Depo Provera, depo-subQ provera 104

Reviews for Medroxyprogesterone

Commonly mentioned side effects
  • Nik...
  • Taken for 1 to 6 months
  • November 5, 2019

Medroxyprogesterone for Abnormal Uterine Bleeding "I got the Depo-Provera shot in May 2019 for my horrible periods, and it was great at first, stopped my period altogether. Then, when my time of the month would come, the shot would make me so sleepy I couldn't keep my eyes open for a week. I asked my doctor, and she said it can cause fatigue, but didn't explain how bad it could get. Never went for shot number 2. Got my period in October, then early in November I started spotting, and it's just been for days. The mood swings being on it and off are terrible. Coming off the Depo, I felt so sick and tired, had horrible headaches. I would never tell anyone to get this!"

2 / 10
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  • Nik...
  • Taken for 2 to 5 years
  • May 28, 2017

Medroxyprogesterone for Birth Control "I have been on the Depo for 5 years now, the only side effects I have experienced were increased appetite and headaches. My last shot expired in March, and I am now trying for a baby. In the last month, I started feeling nauseous, vomiting, tiredness, tender breasts, and an increase in my sex drive. I have done a pregnancy test, but it was negative. Some are telling me that these are the side effects of the shot wearing off. Is this true?"

8 / 10
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  • Kan...
  • Taken for 6 months to 1 year
  • June 10, 2019

Medroxyprogesterone for Birth Control "I took Depo-Provera for about nine months back when I was nineteen (about four and a half years ago) and quit because I moved away from my doctor. I had very light spotting for an extended period of time (about a month) during my first shot, but after that was over, I only had a light period once every three months when my next shot was due. I currently just started up again. I'm three weeks in with not even a single spot. I have light headaches, though those may be because I'm headache prone, no increased appetite/weight gain, no sex drive changes. It's all just a guess, but I still believe this is the right birth control method for me. Plus, it's cheap for me - $10 a shot."

9 / 10
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Frequently asked questions

  • Fri...
  • Taken for less than 1 month
  • January 9, 2019

Medroxyprogesterone for Abnormal Uterine Bleeding "I have large fibroids and endometrial hyperplasia. First, I tried Motrin. The bleeding slowed down, but only until the meds wore off. Next, I took tranexamic acid. The bleeding slowed down, but I had horrible migraines and random sharp pains. So, I stopped and resumed taking Motrin. Next, I tried Norethindrone acetate 5 mg. Side effects were heavier bleeding, larger clots, bad cramping, intense headaches, and extreme depression. Strangely, combined with Motrin, it temporarily stopped the bleeding. However, because of the side effects, my doctor put me on medroxyprogesterone acetate 10 mg (Depo-Provera). This would also treat endometrial hyperplasia. Combined with Motrin, this worked best for me. Side effects are mild cramping and slight headache. I’ve been on this medication for 4 days and have light bleeding. Hopefully, bleeding will eventually stop completely. So far, so good!"

8 / 10
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  • Fri...
  • Taken for less than 1 month
  • January 9, 2019

Medroxyprogesterone for Abnormal Uterine Bleeding "I have large fibroids and endometrial hyperplasia. First, I tried Motrin. The bleeding slowed down, but only until the meds wore off. Next, I took tranexamic acid. The bleeding slowed down, but I had horrible migraines and random sharp pains. So, I stopped and resumed taking Motrin. Next, I tried Norethindrone acetate 5 mg. Side effects were heavier bleeding, larger clots, bad cramping, intense headaches, and extreme depression. Strangely, combined with Motrin, it temporarily stopped the bleeding. However, because of the side effects, my doctor put me on medroxyprogesterone acetate 10 mg (Depo-Provera). This would also treat endometrial hyperplasia. Combined with Motrin, this worked best for me. Side effects are mild cramping and slight headache. I’ve been on this medication for 4 days and have light bleeding. Hopefully, bleeding will eventually stop completely. So far, so good!"

8 / 10
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  • Anonymous
  • March 16, 2012

Medroxyprogesterone for Birth Control "I am 19 years old. I have been on the Depo since I was 16. I got on it after my 6-week checkup. When I first started on the Depo shot, I was a very mean person. I have NEVER in my life been like that. I am a very nice, laid-back person. I gained 40 lbs within the first 3 months. I am not a big eater, and I do eat healthy for the most part. I also had pregnancy-like symptoms, headaches, and bloating. After a year of being on the Depo, my mood had changed, and I became back to myself, and my body got used to it. I really, really LOVE the Depo shot, but I am thinking of switching to another method. I love how I haven't had a period in 3 years and it is 100% effective, but I cannot deal with it making my weight go up and down. Overall, minus a few things, I love it."

8 / 10
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  • Cfi...
  • June 25, 2015

Medroxyprogesterone for Birth Control "Do not get the shot. I got the shot a while ago, at first, everything was alright, but then I got my period, which I've had forever. Now it will not go away. I get the worst headaches that I've ever had before, and they last all day, I get them every day. I feel sick, and I also have started to feel super moody and sad out of nowhere. My body gets achy, and I am starting to gain weight. Definitely will not be getting the shot again, it's not worth it."

1 / 10
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  • ekl...
  • Taken for 1 to 6 months
  • May 6, 2019

Medroxyprogesterone for Birth Control "I was very wary of starting the Depo-Provera shot after reading many bad reviews, however, I have had a great experience so far! I am on my second shot, so about 5 months in. After the first month, exactly 3 weeks in, I had bleeding for 3 weeks straight and bad cramps! However, after that, I have not had a period since. I love how easy it is to use. My boyfriend and I do not use protection of any sort, and I have not since gotten pregnant! I do have daily headaches, but I cannot be sure if it is the birth control to blame, as I am prone to headaches. On the downside, most doctors do not allow this birth control for more than 2 years due to its ability to decay your bones. Overall, great experience! Don't let the bad reviews scare you away and give it a shot! (No pun intended)"

9 / 10
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  • ski...
  • July 19, 2015

Medroxyprogesterone for Birth Control "My experience on depo has been great so far. I've been on it for one year. I don't bleed for days, however, I spot from time to time (not a lot at all). Yes, I have gained weight (only in my thighs and butt). I get headaches, but nothing extremely dreadful. Mood swings! Other than that, I don't experience any other side effects. I haven't gotten pregnant, lol."

9 / 10
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  • Sta...
  • Taken for 1 to 6 months
  • July 25, 2017

Medroxyprogesterone for Birth Control "WORST SHOT EVER!! I just had one shot done and didn't even give the second shot after 3 months a try. Gave me horrible headaches, acne that's so huge I look disgusting to even go out in public, pain on my right ovary 24/7, made me super mad and angry to the point my boyfriend broke up with me, and I'm even off the shot now and still have pain on my ovary. It's been 7 months, and I only had one shot just once and still no period. It's really upsetting, and it makes me suicidal. It also made my boobs tiny, I don't know how that's possible, but they went from C cups to A cups and still not back to normal."

1 / 10
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  • 070...
  • March 15, 2017

Medroxyprogesterone for Birth Control "I opted for the depo shot when I was 16. I was horrible at remembering to take medicine on time, so I chose the shot. This is my experience. I can only speak for myself. I got the shot in May 2006. I stayed on track with the shot due to the reminder I had a doctor's appointment on such and such day. I had light, 3-day periods. Never a day longer, never a day shorter. I had no weight gain. I had no cramps. I had no breakouts. I did not experience any dizziness, shortness of breath, or headaches. I didn't lose my appetite. I had no troubles. Then, like a genius, when I turned 18, I chose to get off the shot, which was due in February. By April, I had a positive pregnancy test. It wasn't hard for my body to change from even after almost 2 years."

10 / 10
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  • Ril...
  • December 7, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "I haven't had any serious complications like most of you have. I've only had slight weight gain, very headaches, and just irregular spotting that would go away within a couple of days of start. My sex drive is the same, I love the fact that I don't have periods. Everyone is different. I'd recommend it."

6 / 10
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  • tyy...
  • Taken for 1 to 2 years
  • February 12, 2016

Medroxyprogesterone for Birth Control "I have been on the depo shot for over a year now, and I regret having it done! Everyone's bodies are different! But my experience wasn't good, put it that way. I always have bad headaches and belly ache. The main problem for me was the weight gain. I used to be size 12, now I'm size 16-18! I always feel depressed and get very moody over little stupid things! I am coming off this and very much considering going on the copper coil, as this doesn't have any hormones. Some advice: if you have had problems on the pill or anything, you will probably get this on the depo. Also, I haven't had any periods on this, which was the only good thing."

2 / 10
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  • Jen...
  • December 4, 2015

Medroxyprogesterone for Birth Control "Ever since I took this shot, I have been having extreme shooting pains up my arm and terrible headaches. I am really scared and have been bleeding for three weeks straight. I would give anything to have never taken this shot right now."

1 / 10
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  • Gra...
  • Taken for 1 to 6 months
  • March 21, 2016

Medroxyprogesterone for Abnormal Uterine Bleeding "First-time depot user, and it has been one of the worst mistakes of my life. It's day 35 post the shot, and I have bled every day with HORRIBLE cramps. I have experienced weakness, dizziness, headaches, depression, and am always tired. I cannot wait until this is out of my system."

1 / 10
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  • Sam...
  • January 6, 2020

Medroxyprogesterone for Birth Control "I had my baby in March of 2019. I got my first shot in June. After research, it's like I only found confident and good reviews, so I thought this was the birth control for me! I was so wrong. After receiving the shot, I had headaches for three days straight, then bled for two weeks. I thought it was my body getting used to the depot shot. After the two weeks, the next two and a half months were perfect, so much so I went back for my second shot. After the second shot, I felt like I wasn't myself, then the great depression came. It almost split up my relationship. I was so up and down. At that point, I was bleeding for weeks. I was due for my third shot days ago, and I have no intention of getting it. It's a joke, and I'm now in the process of waiting for it all to leave my body. I looked up reviews this morning to see if my symptoms were normal, but within six months, the reviews for this contraception have drastically become more and more negative. Unfortunately, that's me done with contraception."

1 / 10
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  • Kat...
  • Taken for 1 to 6 months
  • April 18, 2017

Medroxyprogesterone for Abnormal Uterine Bleeding "I got my 1st shot in Feb 2016. My tubes are tied, but Dr. recommended I get it to help stop the cramps I'd get prior to the shot. I bled the first 3 months after the shot, and it didn't help, so I asked my Dr. if I needed it again. He said to try it for 6 months and stop if it didn't help. I got my 2nd shot in May 2016 and bled for that 6 months. Then I stopped as it never helped with cramps. It's now April 2017, and I still have side effects-mood swings that are destroying my marriage, depression, anxiety, headaches. I've lost 32 lbs (only weighed 122 prior to the shot), dizziness, fatigue, acne, no sleep or too much, feelings of going crazy, and cramps worse than before. I was told with a regular period, the shot will leave."

1 / 10
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  • Meg...
  • Taken for 1 to 2 years
  • January 12, 2017

Medroxyprogesterone for Birth Control "In the beginning, I had bad headaches, vomiting, and nonstop periods. Now, after 12 months of this, the only issue is weight gain. But having a small stomach, I only gained 5 pounds. I have gained and lost (w/o exercising). I would say this is really effective, but with side effects, not so much. I went to see my doctor about my periods. Last time I went in, she said if it doesn't stop after this cycle, I should change birth controls. And she was right! If you think you will stop your periods so soon, stop assuming and give Depo a try! It's super effective, and I'll definitely continue using it!"

10 / 10
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  • Bri...
  • August 19, 2016

Medroxyprogesterone for Birth Control "So I am 19 years old, it is August (a month after my birthday), so I have been on Depo for three years exactly. My first couple of weeks, I had nausea and headaches. After my third shot, I had no menstrual cycle anymore. I will say that this form of birth control is awesome. I was with a guy for a long time and never used a condom, and here I am three years later and have never had a pregnancy scare. So yes, as birth control, it works perfectly. However, throughout the years, I still had some mild cramps and horrid mood swings, and my right knee seemed to gradually get worse. Pains that came and went more when it rained. I am now in the middle of getting Depo Provera out of my system, and I must say I feel like I am dying. Horrible mood swings, nausea, headache."

3 / 10
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  • Mel...
  • March 31, 2017

Medroxyprogesterone for Birth Control "Awful stuff. If you have ever suffered with depression, do not use this because it will make you very depressed - they don't tell you this. Mood swings have been awful, from angry to crying to anxious. I'm like a psycho on it. Constant headaches, tiredness, stomach cramps, heartburn, feel dizzy and weak, nausea... and the hunger! Omg, the hunger... I constantly feel like I haven't eaten for a week, and even after eating a meal, I still have hunger pain. The only good thing it's done for me (except prevent pregnancy) is I am losing weight even though I'm eating more because of the constant hunger. It seems to have made my metabolism go crazy. I've lost 5 pounds in the 4 weeks since I had the injection. Majority of people gain weight though I read."

3 / 10
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  • Cra...
  • March 14, 2017

Medroxyprogesterone for Abnormal Uterine Bleeding "After not being on birth control since I was 19 years old and 'considered' dating men, I took the shot in September 2016 just to play it safe. I bled for 1 month straight, then nothing the next month, then bled a whole month in December. I said no to getting it again as it made me feel bizarre. Well... I haven't stopped bleeding since. Massive amounts of blood clotting and 36864157963 tampons and pads later, swollen 10 lbs weight gain, headaches, mad burning cramps, melasma on my face, and an atrocious attitude directly from hell, still bleeding something fierce. This 'wonder shot' should come with a lifetime supply of femme products and a masseuse named Hans. I was prescribed Provera yesterday. Dear Lord, let it work! DO NOT TAKE THIS FORM OF CONTROL."

1 / 10
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  • Lis...
  • Taken for 1 to 6 months
  • February 16, 2019

For Abnormal Uterine Bleeding "This medicine was prescribed to me for a reason not listed - to correct a heavy menstrual bleeding problem. It worked for the first two months. I take it ten days every month on the first day of my menstrual cycle. 10 MG tablets. On the third month, I started having very, very heavy menstrual bleeding worse than ever, with chronic headache, backache, cramps, and a bad feeling all over my body. The bleeding was so bad that it affected my blood count. After doing a CBC, my blood count was dangerously low. I ended up having to get a blood transfusion, etc. Please be careful with this medication."

2 / 10
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  • Rox...
  • Taken for less than 1 month
  • October 31, 2021

Medroxyprogesterone for Abnormal Uterine Bleeding "This drug is horrible. I have PCOS, and I was spotting with some medium bleeding since May. When October came and my spotting didn't stop, my OBGYN suggested Provera (10 mg/twice a day), and at first, it stopped it for like a day. Then I started bleeding profusely, soaking through heavy-duty pads every hour, couldn't work, horrible cramps that left me in a fetal position, and I have even lost my appetite. I have headaches, and the bleeding is so bad that it wakes me up throughout the night, and I have blood clots galore every time I use the bathroom. It is a nightmare that I wish I will wake up from. I am going on my third straight week of this, and it's miserable. If anything, Provera has made my symptoms worse."

1 / 10
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  • Que...
  • Taken for less than 1 month
  • January 14, 2022

Medroxyprogesterone for Abnormal Uterine Bleeding "So, after I gave birth to my fifth child at age 42, at my postpartum appointment, my ob/gyn sold it to me as though I was going to spot anyway while nursing. I'm angry he didn't tell me I can bleed for 3 months or longer on this injection. Within days, I became enraged, I didn't like my newborn at all and could care less about it (which I have never felt until after the shot. I also never felt that way with any of my babies). Not only did I feel enraged, but I started spotting within days, lost my sex drive, then went into light bleeding the 2nd week, then the 3rd week getting blood clots, now going into my 4th week with huge blood clots. I'm taking iron now. I also have headaches every day. When I looked up reviews about this depo shot, I was crying almost every day and beating myself up for taking this shot. This stupid drug has jacked up my sex life with my husband, and I obviously have no desire to have sex on my period with all these blood clots coming out. I will never again take this shot nor recommend it."

1 / 10
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  • Dep...
  • February 6, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "I have been on the Depo for 13 years, and it has been great. No periods, not even spotting. But I did, however, gain a lot of weight, and I have experienced headaches. But I just stopped because I have been on it too long. It will cause bone loss. I probably experienced a lot of the side effects, but nothing worse than bleeding and cramping for months at a time. I would definitely go back to it if I could."

8 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.