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Medroxyprogesterone and Headaches: What Users Say (Page 3)

Brand names: Provera, Depo Provera, depo-subQ provera 104

Reviews for Medroxyprogesterone

Commonly mentioned side effects
  • Ceb...
  • Taken for 1 to 6 months
  • July 1, 2017

Medroxyprogesterone for Abnormal Uterine Bleeding "I just had my first shot 2 months ago. I have not been myself, constant headaches, serious contraction pains, loss in sex drive. I have been bleeding for almost a month. I feel sick all the time, no energy, and I am experiencing hyperpigmentation on my face. I have become so dark, also I can't sleep well and loss of appetite. I can't wait for it to wear off. I am not getting it again. I hope I return to my normal self after it wears off."

2 / 10
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  • Dau...
  • Taken for less than 1 month
  • April 5, 2021

Medroxyprogesterone for Abnormal Uterine Bleeding "I am here for my mom. She had been bleeding for 14 days before her OB recommended this drug. It stopped her bleeding right away, but the side effects on my mom are extreme. It's been more than 10 days since she started taking this drug, and ever since then, she's so weak she couldn't even stand. Her back is in pain, she's having trouble breathing and sleeping, drowsiness, headache, and she even lost her appetite. My mom couldn't write a review because she's currently admitted to the hospital. If this drug is good for you, then great, but my mom's experience is a nightmare."

2 / 10
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  • Bas...
  • Taken for less than 1 month
  • January 6, 2022

Medroxyprogesterone for Abnormal Uterine Bleeding "I was prescribed 10 mg of Provera daily beginning on December 16th to control a nine-month continuous menstrual bleed. It is now January 5th, and there are no signs of this nightmare ending. This drug has left me with side effects of anxiety, depression, exhaustion, heart palpitations, headaches, and of course still bleeding with clots the size of my fist! Doctors don’t return calls, and appointments aren’t available until over a month away! I’ve suffered far too long, and I’m about to give up. My quality of life is pretty low right now. I have an appointment with a new OB-GYN, so I’m hoping for answers and an end to this mess. Maybe I’ll be in bad enough shape for an emergency hysterectomy while I’m there. My career is about to end due to the inability to leave home without bleeding all over the place! I’m 49 years old, and I feel like I’ve wasted a year trapped in my home from this. This medication has been as useless."

1 / 10
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Frequently asked questions

  • You...
  • Taken for 1 to 2 years
  • April 17, 2019

Medroxyprogesterone for Abnormal Uterine Bleeding "I have been on Depo for about a year and a half. I was loving this form of BC until about 3 months ago. I started having massive and debilitating headaches that would last 2-3 days after getting shot. My last shot (a month ago) I started bleeding 2 days before I got my shot and have been bleeding ever since. It's rather a heavy flow and goes from being brown for a few days to bright red with clots (with horrible cramps) for a few days then back to brown blood and keeps alternating. I have never even spotted from the beginning of taking this drug until this last month. I have an appointment in a week to get a PAP and lab. Will update on how this goes."

6 / 10
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  • Roc...
  • December 2, 2015

Medroxyprogesterone for Endometriosis "Do not get this shot! It tried to ruin my life. Heavy sporadic bleeding, mood swings, depression, headaches, body aches, no sex drive, terrible cramps. I have little/no emotion for almost everything. I only had 2 shots. I just want to get back to my normal :("

2 / 10
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  • J89...
  • October 30, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "I took this birth control about a month ago, and at first I loved it. I was spotting for about a week after I got it, and then I stopped for maybe a month. 11 days ago I started spotting a brown colored period blood. Now it's very prominent, heavy, and red. I've been on this period for 12 days now, and I'm sick of it! I'm very moody and ALWAYS hungry. Always tired and always have headaches. I'm never irritable, and this is not me. I've gained 4 pounds. And yeah, this medicine helps prevent pregnancy, but only because you can't have sex. You're always bleeding and moody! Who wants to have sex under those predicaments? I would never recommend this medicine to anyone! And I sure am never ever getting it again!"

1 / 10
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  • kek...
  • Taken for 1 to 6 months
  • March 1, 2016

Medroxyprogesterone for Birth Control "I hate this drug! The side effects are awful! I woke up feeling the worst nausea every morning, to the point where I would sometimes vomit. It causes awful headaches. I had a really large clot once, along with killer cramps. My period was still irregular. Yes, it was not as heavy, but it did cause spotting for a majority of the 3 months I was on it. My skin (which happened to be getting clearer!) was breaking out throughout the 3 months and in places that I never used to break out in. Also, I went from being one of the happiest people to majorly depressed with anxiety and mood swings. I now have the worst panic attacks. It will also make your sex life become horrible! Please don't take this! Read all the reviews before you do!"

1 / 10
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  • HBM...
  • April 20, 2014

Medroxyprogesterone for Birth Control "I'm 16 years old, and I have been on the shot since July 2013. I haven't had any of the side effects like having unusual cramps, headaches, or acne. The only problem that I have is I spot on and off for about 2-3 weeks right before I'm supposed to get my next shot."

9 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • March 22, 2013

Medroxyprogesterone for Birth Control "I've been on the Depo shot for a year and a half. I love it because I'm not getting any periods, and it's not like the pill, having to remember it daily. However, in the course of being on this shot, I have gained 70 pounds. I'm always hungry, and I get very moody. I also have extremely bad headaches. I'm switching to the NuvaRing because my weight gain is unbearable, and my headaches are chronic."

4 / 10
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  • Ann...
  • Taken for 6 months to 1 year
  • June 24, 2019

Medroxyprogesterone for Birth Control "Got the Depo Provera shot back in September of 2019 after I couldn’t stand my heavy, painful periods while on the pill (took that for two years). Once I got the shot, I never got another period. It works so great for me! I get headaches every now and then, but for me I’ve always had bad headache issues, and the Depo didn’t make it any worse. I haven’t noticed any weight gain, but I don’t work out like I should anyway."

9 / 10
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  • Dan...
  • July 1, 2016

Medroxyprogesterone for Abnormal Uterine Bleeding "It's been about three months for me, but these last three months I've been bleeding for two weeks straight every month, and this month it's going on three weeks. It sucks. I'm having bad mood swings and real bad headaches."

1 / 10
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  • TNV...
  • Taken for 10 years or more
  • October 26, 2016

Medroxyprogesterone for Birth Control "I've been on Depo full-time since I was 22. I'm now 34 and still on it. I am so in love with this birth control, it's almost like an addiction for me. In the beginning, I did have some side effects with the first few rounds of shots: headaches 4 to 5 days a week, but nothing a couple of Tylenol couldn't handle. Some slight weight gain and mood swings. After a week on the first shot, my periods stopped completely. I have not had a full-on period in 12 years. I have spotted a few times, but that happens maybe twice a year, and even then, it's only for a day at the most. I'm still having mood swings, but those only seem to be during the week of when my shot is due. It absolutely fits into my plans of NEVER having a child. It's the best!"

10 / 10
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  • nec...
  • January 28, 2014

Medroxyprogesterone for Birth Control "I am 4 weeks into the shot and feel horrible! My sex drive is gone, side pains, cramps, headaches, and so tired all the time. My mood swings make me feel like I am crazy! Oh, and now I have this metallic taste in my mouth. I just want to sleep all day because of the constant cramping. I feel horrible. My face is changing too! I am Black and my face looks so dry and discolored."

2 / 10
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  • Thi...
  • February 3, 2016

Medroxyprogesterone for Abnormal Uterine Bleeding "I have been bleeding for 5 months now. I only got one shot, and ever since I didn't get the second, it's been nonstop heavy bleeding for two months. All I can ask is when will the bleeding, depression, and headaches stop."

1 / 10
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  • emm...
  • Taken for less than 1 month
  • July 11, 2014

Medroxyprogesterone for Abnormal Uterine Bleeding "After 5 years of not getting the shot, I decided it was time again. Endometriosis is very painful, and it had returned, so it was time. The last Depo Provera shot was great: no periods, no weight gain, no hormonal imbalances. This time, I have the hormones of a pregnant woman, and I've been bleeding heavily for two weeks since giving myself the shot. I don't have cramping too bad, and my face has cleared, but this hormonal imbalance, headaches, and heavy bleeding are kicking my butt-I'm even more tired than normal."

6 / 10
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  • Ran...
  • Taken for less than 1 month
  • February 28, 2020

For Amenorrhea "I recently miscarried in December 2019. My period came back in January 2020, and it was horrible. I decided to take this medication because of the miscarriage. I miscarried because my progesterone and HCG levels were low. So I took this medicine in February 2020 to hopefully get my cycles back on track. They have always been irregular, or I'll skip a month. So we are hoping the medroxyprogesterone helps with my cycles. Taking the pills, I cramped, had breast pain, dizziness, headaches, hot flashes, and I had trouble sleeping the 7 days I took it. It took 9 days after stopping the medicine to get my period back, and honestly, it hurts a lot, and it's heavy. It feels like I'm miscarrying again, even though I'm not. Hoping the medicine was worth it and my cycles and hormones go back to normal."

8 / 10
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  • Ray...
  • January 26, 2020

Medroxyprogesterone for Endometriosis "I was put on the Depo shot a year ago to help treat my extremely painful periods. It stopped my menstrual cycle, so for a year I've been able to avoid the terrible pain I was in every month. However, the side effects have been awful. My whole face is covered in painful acne, and I didn't have this problem before the shot. I've experienced terrible headaches, I've spotted the whole year I've been on it, and had other discharge as well. My anxiety is through the roof, and it has worsened my depression. My advice is to stay far away from the shot if you can avoid it. I can say it's been nice not having the terrible pain endometriosis was causing me every month, but the other side effects are almost just as bad. I just had my last shot and will never take it again."

2 / 10
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  • All...
  • Taken for 1 to 2 years
  • July 24, 2017

Medroxyprogesterone for Birth Control "I am so thankful for this birth control. I switched from the pill to Depo because the pills gave me horrible anxiety and depression. Immediately after I switched, I was myself again. After two doses, my periods stopped. I know birth control affects everyone differently, but I have had no negative side effects at all. My only complaint is after every injection, I would get a headache for a couple of days. I'm 21, and I just hit the two-year mark, and my doctor recommended that I switch to a different BC this month, and I'm so sad and nervous... I am worried about getting the negative side effects of a new BC after being worry-free and comfortable for 2 years."

9 / 10
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  • Mil...
  • Taken for 1 to 6 months
  • July 18, 2015

For Endometrial Hyperplasia, Prophylaxis "I am 32 y/o. I was diagnosed with polycystic ovaries and have always been very irregular with my periods to the point of going for 5 to 6 months with not even a drop of blood. Recently, my doctor found abnormal cells in my uterine lining, he prescribed medroxyprogesterone for 3 months, 1 pill daily. I am done with the treatment now, and during the 3 months, I got my period 2 times only. Overall, I felt fine-no major side effects. I only felt a little dizziness and a few headaches. I also put on some weight, but with exercise, I have managed. I feel great and can't wait to see the results of my next biopsy."

9 / 10
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  • Ash...
  • Taken for 2 to 5 years
  • June 30, 2019

Medroxyprogesterone for Birth Control "This is my second go-around with Depo, so I already knew what to expect. My first time on Depo, I was on it for almost 3 years. In the 3 years I had it, I never had a period, nor did I gain weight. After getting tired of going to the doctor every 3 months, I switched to the IUD. After 2 years, I was ready for it to come out. So I went with something I knew: Depo. I love Depo, no period. The only bad thing I can say about this drug is I do have a headache after getting my shot. The headache only lasts for an hour or so. Everybody is different, and their bodies react differently. This is a win-win for me. No periods = no babies."

10 / 10
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  • loc...
  • Taken for 1 to 6 months
  • August 14, 2015

Medroxyprogesterone for Birth Control "I didn't get pregnant, which is the only reason I'm rating this a 2. I have been bleeding for 56 days straight as of today. Since I got the shot, I have experienced severe fatigue, 1-3 hour long headaches, appetite issues, inability to get out of bed, and horrible cystic acne."

2 / 10
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  • Kur...
  • Taken for 2 to 5 years
  • June 14, 2015

Medroxyprogesterone for Birth Control "So, I've been on Depo for two years now. And I'll say, it has been the worst! I've gained 12 lbs. I have constant headaches and backaches. I'm very moody. I spot one month after getting the shot up until I get the next shot, then it repeats. I have bad cramps and lots of hot flashes. I'm getting off the shot next month because this just isn't the BC for me."

5 / 10
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  • deb...
  • October 30, 2020

For Abnormal Uterine Bleeding "I was put on this medroxyprogesterone for 10 days at a dose of 10 mg because I had my period heavy nonstop for 2 months due to PCOS. It worked, but 2 days after I was done with the pills, I started heavy bleeding again, but even worse than before, with HUGE clots. I’m having terrible cramping and headaches too! IDK what’s going on, but this is day 3 of heavy bleeding after my 10 days of these pills, and I’m praying the bleeding doesn’t last long! These pills are horrible, reading all these reviews of heavy bleeding and huge clots for MONTHS because of this drug?! Why would they give this to us!? Big Pharma is the WORST."

1 / 10
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  • Laz...
  • November 16, 2016

Medroxyprogesterone for Birth Control "I stopped taking Depo because of the depression and lack of sex drive it was causing me. I had the spotting in the beginning for about 3 months, and after the second shot, I felt dizzy all the time. I'm in the process of getting it out of my system, and it's an absolute nightmare. Since skipping my last shot, I've had heavy spotting and headaches almost every day. I can't sleep through the night at all, and I've been having an increase in nightmares that I'm certain is related to the birth control. My dreams were never this bad before. My hair also started thinning badly, and I had to cut about a foot of it off. I loved my long hair. DO NOT get this shot. The side effects are not worth the risk."

1 / 10
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  • Vic...
  • August 21, 2016

Medroxyprogesterone for Birth Control "I got my first shot in June 2016, thinking it would be a better alternative from the problems I was having with the pill. I ended up bleeding for a whole 3 months, which defeated the purpose of getting it for birth control because I couldn't have sex anyway because of it. I got a second shot in August, and the bleeding stopped, but I started getting headaches and feeling dizzy frequently. My next shot is scheduled for October, but I refuse to get another after reading other women's reviews and horror stories. The side effects are insane and not worth the risk. I would never recommend the shot to anyone."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.