Lubiprostone and Headaches: What Users Say (Page 2)

• nic...
• Taken for less than 1 month
• November 18, 2018

Lubiprostone for Irritable Bowel Syndrome with Constipation "I took Amitiza for 3 days. I had blood pressure spiked, sweats, severe jaw pain, sick to my stomach, headache. I called the doc on the third day, he told me to stop it immediately and if the symptoms don't go away, go to the ER. Oh, and it didn't relieve my constipation at all."

• Lee...
• Taken for less than 1 month
• January 13, 2021

Lubiprostone for Chronic Idiopathic Constipation "Was given this for constipation. I had severe nausea and headache. I was certain I was going to vomit for several hours after each dose. I felt like I had a severe stomach virus. It was so debilitating I had to stop taking it after two days."

• HLa...
• Taken for less than 1 month
• October 2, 2020

Lubiprostone for Chronic Idiopathic Constipation "My doctor gave me Amitiza and Linzess in his office to take for chronic constipation. Within 10 minutes, I went to the bathroom all over myself, and then came the severe diarrhea. I went over 50 times in 5 hours. I had a headache, nausea, and stomach pain. I started getting dizzy and briefly passed out. Called the nurse, and she said to call the ambulance. I got to the ER, waited 5 hours, then got rehydration. It was awful. I told my doctor, and he said to just take Linzess if needed."

• Ela...
• September 13, 2017

Lubiprostone for Chronic Idiopathic Constipation "I have taken two doses, and it didn't work at all. Was it placebo? I have no idea. What happened was that I experienced strange psychotropic effects: lessened ability to judge distances, lessened ability to follow conversations, slower reading speed, headache, facial muscle spasm, clenching my jaw, and then a crying episode after 4-5 hours after the dose. At least I know it didn't cause my acne. I am scared to try the higher dose after reading everyone's comments and the fact that my blood pressure runs low to begin with. And the fact that my stomach is prone to nausea."

• Ela...
• November 3, 2019

Lubiprostone for Chronic Idiopathic Constipation "I recently took one 24 mg Amitiza pill, prescribed by my physician, and within an hour, I thought I was dying! I had 8 bowel movements in 2 hours, and 6 more in the next 5 hours. The stomach pain was unbearable, accompanied by a horrid headache. My mouth was so dry that I could not swallow; I could not calm my rapid breathing; I was freezing cold and trembling uncontrollably. To say that my husband and I were terrified is an understatement! We were at the point of calling 911 when the stomach pain began to subside --- slightly. Two days later, I am terribly dehydrated and weak. I'm glad this works for some people, but if you are a 135 lb senior citizen, please stay away from it!!!!"

• Lg2...
• May 28, 2016

Lubiprostone for Chronic Idiopathic Constipation "I was diagnosed with celiac disease in 2007. Emergency gallbladder removal in 2009. Over the years, my digestive system has been malfunctioning. Last year, I had trouble digesting certain foods. In February, I was rushed to the hospital due to severe vomiting and abdominal pain. All the food I threw up was undigested, and my stool was black. Went through many different tests and was put on Amitiza. It was probably my second worst experience with a medication. In the first week, I had extreme headaches, I felt fatigued, had abdominal pain, and severe mood swings. I was put on Linzess and have been going ever since!"

• Anonymous
• July 13, 2011

Lubiprostone for Chronic Idiopathic Constipation "I take two 8 mcg capsules daily, and it does work without any side effects, except I have had some mild headaches, but don't know if it is from the Amitiza or not. It has really helped with my constipation, but I do get quite a bit of gas and have to go to the bathroom more times a day, but that is better than constipation."

• All...
• Taken for 1 to 6 months
• August 25, 2018

Lubiprostone for Irritable Bowel Syndrome with Constipation "When I started out taking Amitiza, it worked great at 24 mcg twice a day, but after 1 week, I started to get very sick every time I took it. My symptoms were syncope, dyspnea, nausea, vomiting, loose stool, heart palpitations, rapid heart rate, chills, sweating, headache, and tunnel vision. I tried taking it once a day, still had all the same effects. After talking to my Dr., we decided to go to 8 mcg twice a day. I didn't take any for 2 weeks and started taking the 8 mcg twice a day. After the 11th dose (1st dose day 6), I started experiencing nausea, syncope, dyspnea, headache, chills, skin stinging, and cold sweats."

• Hal...
• Taken for 6 months to 1 year
• December 29, 2019

Lubiprostone for Irritable Bowel Syndrome with Constipation "I was prescribed Amitiza for IBS. I’ve tried both the higher and lower dose. As others have mentioned, it causes nausea, bloating, and cramps. The higher dose caused all that plus headaches. It took several weeks to “work,” and even then I continued to have issues. I’ve been on it about 8 months now, and I’m considering stopping the medication as it no longer does anything. Though I must say it worked well for a period of time."

• wys...
• Taken for 6 months to 1 year
• September 2, 2020

For Constipation "Lubiprostone has worked very well for me. It was one of only two or three medications that my insurance would cover for constipation. I do not have IBS-C, just chronic idiopathic constipation. I've been on it about 6 months. The first month or so was pretty rough - shortness of breath, bad headaches, diarrhea, the works. But if you stick with it, these side effects will subside. The only things I have now are just a tiny slight pressure in my chest and a runny nose right after I take it, lasting about an hour. My only complaint is the cost. It is very expensive. I am hoping that one day soon there will be a generic prescription available."

• sar...
• Taken for 1 to 6 months
• September 4, 2024

For Irritable Bowel Syndrome "I am not sure. Lately, I have been experiencing headaches, I have gained weight, etc. It does usually help me with constipation, though."

• Anonymous
• October 11, 2012

For Constipation, Chronic "Having two 8 mcg capsules daily, and it does work with side effects. I have had some headaches and nausea. It helped my constipation a lot, though. Bottom line, it works for me."