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Linzess for Irritable Bowel Syndrome with Constipation User Reviews (Page 4)

Linzess has an average rating of 6.5 out of 10 from a total of 220 reviews for the treatment of Irritable Bowel Syndrome with Constipation. 55% of reviewers reported a positive experience, while 28% reported a negative experience.

Reviews for Linzess

  • riisey
  • Taken for 1 to 6 months
  • August 1, 2013

"I have suffered from irritable bowel syndrome-constipation for 16 years and I had tried just about everything on the market. I finally gave up and after a few years of having nothing my new doctor gave me Linzess. I was sure it would be like most of the others but it worked right away and has continued to work for 3 months. I love it. Thank you to the pharmaceutical company for this product. My bloating and bad cramps have gone away. I did have to change how I take it, it says to take 30 minutes before I eat but I take it after I have eaten some of my meal because it seems to work better. I will say that you must be near a bathroom when the urge to go hits because you can't hold off."

10 / 10
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  • M King
  • August 19, 2015

"I started on linzess in April 2015. I thought it was my miracle drug, but it seems to have stopped working as well, and I have severe bloating/ abdominal distention. To make matters worse, I've gained weight. Not water weight either. I work out and eat low carb, but since starting linzess the scale is going up. It's looks as though I'm not the only one. Linzess needs to list potential weight gain as a side effect. But why would they do that? It's all about sales."

3 / 10
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39 Report
  • Sun...
  • Taken for less than 1 month
  • February 2, 2013

"I tried this new medicine from my Doctor's sample. 290 once a day. It worked the first time within one hour from swallowing. I usually have a movement once a week, I had fourteen movements that one day, unfortunately they became all water after the first couple. I took the following couple days off to get rehydrated and then tried it again, I think I am on my tenth movement in three hours from taking. The pill did take away my pain and cramps but I had to cancel my plans for the day but it is well worth not having the pain and cramps of constipation."

7 / 10
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46 Report

Frequently asked questions

  • rababc
  • Taken for less than 1 month
  • March 12, 2015

"IBS-C my entire adult life (44-yr old female.) I have done it all - tried everything natural and prescribed. I cut out dairy, gluten, red meat... Was drinking prune juice, using fleet supps almost daily, NEVER having a decent or "normal" BM. My GI doc gave me samples of Linzess yesterday; I took it this morning and exactly one hour later : WHA-LA. A "perfect" BM!!! NO cramps. NO diarrhea. If you have trouble going, please try this. I am absolutely thrilled! Not sure what my insurance will cover, but I don't even care - this is my miracle pill, and it is going to make a huge difference in my life."

10 / 10
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38 Report
  • Beach...
  • Taken for less than 1 month
  • June 8, 2022

"I tried to give it a chance but it made me sicker each of the 16 days I took it for my chronic constipation/IBS. Within a half hour of taking it I developed headache and nausea. Following days had same along with diarrhea and sharp belly pains. I'll stick to my natural remedies and healthier foods."

1 / 10
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12 Report

Are you taking this medicine?

  • Airam
  • June 11, 2016

"I have been using Linzess for over a week. I had a lot of success with Resotran for three years until it stopped working. I was back to being bloated/distended and constipated. I also gained weight when I noticed that the med were not working any longer. I was miserable. I did some research and realized that Linzess was available and covered under my insurance plan. My doctor gave me a prescription and I finally found relief again!! All the reviews I read made me a little nervous but it's not as bad as I thought. It does clean you out! I take the med in the morning 1/2 hr before I eat and within 2-3 hrs I have at least three bowel movements. My bloating/distension has improved and I lost weight. I hope it continues to work!"

8 / 10
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34 Report
  • Peggy
  • Taken for less than 1 month
  • July 26, 2019

"Took the 290mg dose and less than an hour had severe cramping and bloating! Passed a lot of foul smelling gas and about an hour after had explosive watery diarrhea! I will not recommend this drug although it helped with the impaction quickly the smell is awful and the cramping and diarrhea is not worth it unless it’s last resort! Try lactose medium-chain triglyceride (MCT) oil or which works much better with less side effects"

2 / 10
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23 Report
  • Geise...
  • Taken for less than 1 month
  • May 21, 2017

"I started this a week ago because I was having incredibly intense cramps and nausea every time I needed to poop. I experienced massive diarrhea about an hour after I took it. I have other digestive issues, including Gastroparesis, GERD, and kidney problems, so I'm used to these issues. So I continued to take it and deal with the fallout diarrhea. Yesterday, I had the best day I've had in months. When I took the linzess, I didn't have the diarrhea and in fact had a normal day! I think this stuff might be effective if you can get past the initial diarrhea part and let it work for a week or so. I'm a little nervous about reports that it stops working after a month, but I'm going to see what happens."

8 / 10
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30 Report
  • Hazel
  • Taken for 1 to 6 months
  • January 30, 2020

"I've suffered from constipation all my life, after turning 50, I have allergies of food, peanuts and cayenne pepper. Some medication also. I took Linzess yesterday and this morning had diarrhea, I am weak, dizziness, headache, tongue tingling, my chest tightened, and have bled from rectum, small blot, but scary. I'm just not taking it anymore. I have benadryI to take for head aches. I've taken Linzess one other time and that's why I quit it, but forgot. So everyone's different, but I can die from allergies. There needs to be more information and drug interactions done on theses kinds of medicines. And doctors & NP's check your patients medical file."

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  • Jeffs...
  • Taken for less than 1 month
  • February 23, 2015

"Severe diarrhea started in one hour with about 5 ounces discharge every 2 minutes. Was not able to consume water fast enough to prevent dehydration. Diarrhea slowed after a couple hours. Most diarrhea was over after 6 hours."

8 / 10
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37 Report
  • Bink
  • Taken for 1 to 6 months
  • January 4, 2020

"I’ve been on this medication since November at 145 mcg and I either have mostly watery diarrhea to where I have to run to the bathroom and then there are days where I’m just constipated. I have rarely had any normal bowel movements since starting the medication. Not sure if I need to up it or lower the dose."

1 / 10
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21 Report
  • JKK
  • Taken for 6 months to 1 year
  • March 22, 2024

"Senior, bowel inconsistencies started a year ago. Nothing helped until Linzess 72. I take it at 4 AM, and between 2 to 3 hours later, I have the first movement followed by 3 to 4 other movements. It kind of knocks me out for the rest of the day. Lots of gas. I don't take it every day; it's a trade-off between constipation or upset."

7 / 10
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2 Report
  • JRano
  • Taken for 2 to 5 years
  • January 9, 2021

"Linzess has been a blessing. I’m in my 50’s and have had constipation issues half my life. Later diagnosed with IBS, diverticulosis, and partial anal stenosis. My preferred regimen after a few years of using it, is early morning every other day. I make sure I have a 4 hour window of non-interrupted bathroom access. The 1st bowel movement begins at an 1 hour and 15 to 20 minutes after taking the medication. Then several more times for 3 and a half to 4 hours. Yes, it gives me diarrhea but that’s nothing compared to the years of pain and discomfort."

9 / 10
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17 Report
  • Anonymous
  • Taken for 1 to 6 months
  • March 1, 2017

"Linzess has been extremely helpful for my constipation. I am able to go every day now, sometimes more then once. My only two complaints are the diarrhea and weight gain. I am a bit of a gym addict and go at least 5 times per week, running and weight lifting. I have a very healthy diet around 1300 calories a day, high protein and fiber, low fat, low carb and low sugar. Since I have been on Linzess (4 weeks consistantly), I have gained 7lbs. I believe I am retaining water despite being able to go to the bathroom often. This is the only drug that has worked to alleviate the constipation and I have tried MANY! However, I am not happy about the bloating and weight gain."

7 / 10
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30 Report
  • alnat...
  • Taken for less than 1 month
  • July 22, 2013

"I've suffered from Irritable Bowel Syndrome almost 30 yrs & before I started taking Linzess the only thing that helped me was Perideim it gave me an opportunity to visit the bathroom twice sometimes three x's a day, which meant a lot to me, but I had to take it a certain time of the day which was fine because I didn't have to be confined in the house. But my Dr. referred Linzess to me. The only difference is this works quicker & I can't stress hard enough how important it is to be near a restroom, I give 10 thumbs up to the makers of this medicine it really helps me but unfortunately I have to return to taking my Peridiem, Lizness is too expensive!"

10 / 10
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40 Report
  • Ameck
  • Taken for less than 1 month
  • January 17, 2020

"Awful medicine! I know the side effects are listed but you might as well stay cooped up in your house for two weeks running to the bathroom. Nauseous, dizzy and diarrhea severe, not worth it. Try natural supplement instead."

1 / 10
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20 Report
  • Gadge...
  • September 10, 2013

"Oct-2012, Had colectomy with anastimosis because muscle and nerves had stopped working on colon and I let it go too long because nothing helped. If only I had this few years ago before I gave up hope. Praying it will save small intestine that's left. As a Plus, it takes the 8 pain from irritable bowel syndrome flare down to a livable life. Maximum dose. If I didn't have a Fibromyalgia flare & lesions formed inside I'd be perfect. Gives me hope & gives hope to many who were losing options. Did have to Fight Blue Cross to cover but hey realized it was cheaper than many ER visits for pain & constipation. Makes life easier. Thank You for helping me get my life back. Had almost given up."

9 / 10
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39 Report
  • AngiS
  • Taken for 6 months to 1 year
  • February 28, 2015

"I did not have any diarrhea when I started it and I have been using it for 6 months. I have noticed a big difference in the last 3 months in that my stools are much smaller and softer. The biggest difference for me is pain reduction. My episodes of crippling abdomenal pain has all but stopped. That has changed my life!"

8 / 10
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35 Report
  • Spear...
  • May 13, 2015

"I have such severe constipation that I end up in the emergency room for it because I'm so full I can't eat or drink for days. My stomach will not growl for days because there is no room. I will go weeks and no bowel movement. I tried everything even prescription medications as far as them giving me the stuff you drink when you get a colonoscopy. My doctor finally gave me linzess. I take 145 in the am. First two days I did have watery stools pretty quick after taking. Next few days it was hours and I only had regular bowel movements. Every few days I do have watery stools. I am still new to the meds. So far though this is a miracle!!! Before I couldn't eat, drink, leave the house, sleep for days because of the pain."

10 / 10
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34 Report
  • not2O...
  • Taken for less than 1 month
  • April 23, 2023

"My doctor prescribed this over-priced medication about 10 years ago when I still had insurance that would cover most of the cost. At that time I gave up after a few days because it wasn’t working at all. Just recently it’s been prescribed for me again and my doctor gave me some samples. Why is there no generic yet? This stuff has been around forever. I decided to check the reviews, and now I’m afraid to take it. If I have to stay home and close to a bathroom every day until noon I can just keep using Miralax and spend a lot less money. Right now I’m afraid it’s not going to work and I’m afraid it is going to work. I will update this review after a few more days if there are significant developments. Meanwhile our government should be fixing the fact that we can’t use our dismal 50/50 chance on a more reasonably priced generic."

1 / 10
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7 Report
  • Mista...
  • Taken for less than 1 month
  • November 26, 2018

"Don't take this drug!! I took one pill 30min before dinner, woke up at 5 am and had explosive diarrhea for 30 mins. The next day severe abdominal pain that I had to go to the ER and take painkillers all day. Is now 2 am two days later and seems that pain has finally faded. Never again!!"

1 / 10
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23 Report
  • Lilib...
  • Taken for 6 months to 1 year
  • August 22, 2017

"This drug has changed my life! I have dealt with chronic constipation and bloat for 30 years. Not any more! I started taking it everyday but now take as needed due to having regular bm's on my own since starting this drug. I see people stating it doesn't work for them. Trick is to drink at least 8oz. of water with it 30 minutes before you eat. The more water, the faster/better it works. I have bm' s within an hour every time. Cost. I have insurance and the company has an online coupon code to use at the pharmacy. Regular cost is $410.00, with insurance is $150.00, and with coupon it costs me $60.00. That's still expensive but better than $150.00. I love this medication! Happy pooping!"

10 / 10
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27 Report
  • Nikki...
  • June 13, 2013

"Only medication I've ever taken that actually works like a charm. It is expensive but worth it. I've suffered with Irritable Bowel Syndrome for 8 years and have never had anything to relieve my symptoms."

10 / 10
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38 Report
  • Shel
  • Taken for 1 to 2 years
  • June 17, 2023

"Linzess is working great. After not having a BM for 7 days, I went to the emergency room where the hardened stool had to be digitally removed -very uncomfortable! I was diagnosed with IBS-C and started on Linzess 145mcg 18 months ago. I find that taking it every other day, occasionally every third day, gives me a BM that day and also usually on the second day. My only negative is the price. On Medicare Advantage, if I took it every day my cost would be $47/month but the charge toward the do-nut hole would be over $6,000 per year."

10 / 10
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6 Report
  • faery...
  • March 9, 2017

"I have been taking Linzess 290 mg for over 3 months now. In the beginning I had a few experiences of diarrhea but not so much now. What I cannot take is the stomach pain, gas and bloating which has gotten worse over time. I stopped taking the drug for a few days to determine if these symptoms were from the drug and they were. The stomach paid came right back today when I took a dose. While it does help with the constipation it is not worth the other side effects. Back to magnesium capsules I go."

5 / 10
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27 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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