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Lupron Depot and Weight Gain: What Users Say (Page 2)

Reviews for Lupron Depot

Commonly mentioned side effects
  • khe...
  • October 22, 2009

For Endometriosis "I just had my second shot 6 days ago. I will admit that my pain from the endo is a great deal better than it was. I was a few days late to get my 2nd shot and could feel the symptoms coming back slowly. The side effects are miserable. I don't want to finish out the treatment. Going for a second opinion. Will be trying estradiol today for the hot flashes, which have been the worst, at least 3 an hour, and all night long. Haven't had any weight gain so far, weight loss, probably because I am so paranoid about gaining."

2 / 10
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14 Report
  • Bru...
  • Taken for 1 to 6 months
  • December 26, 2024

For Prostate Cancer "I am taking this drug along with 10 mg of Prednisone, so some of my symptoms may be from either drug. I've been taking Lupron Depot for four months and the prednisone for eight months. Hot flashes, 15-20 per day. Lasting 3-4 minutes. Dizziness, but much better since I stopped taking Flomax. Weight gain, always hungry. Prednisone does this to me. Fainting, may be dehydrated at times. A bit of chest pain, but not serious."

9 / 10
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1 Report
  • Mar...
  • Taken for 1 to 6 months
  • September 28, 2024

For Uterine Fibroids "I have been on Lupron for 4 months, about to have my fifth shot. I have a 10 cm submucosal fibroid which was causing pain, severe bleeding, and anemia. Since starting the Lupron, my migraines increased by double (I had to switch meds so I could go to work). I’ve gained 10 pounds, I have night sweats, hot flashes during the day, my mood gets angry and sad the week after the shot, and now my hair is thinning. I also am still bleeding daily (spotting). I was put on progesterone to offset some of the side effects. I have two more shots until my second surgery, and I can’t wait to be off this medication."

5 / 10
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1 Report

Frequently asked questions

  • fat...
  • Taken for 1 to 6 months
  • June 1, 2023

For Prostate Cancer "Tried Lupron Depot every 3 months two times, but severe fatigue, occasional dizziness, and passed out. Side effects were not acceptable to me. Orgovyx + Xtandi is much better. Although, without testosterone: fatigue, no erection, lack of enthusiasm, and weight gain."

3 / 10
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  • End...
  • Taken for 1 to 6 months
  • April 27, 2023

For Endometriosis "I am a 22-year-old Black woman who started taking this injection in February after undergoing diagnostic surgery for endometriosis. I don't know what stage of endo I'm in, but it has spread to my intestines, liver, ovaries, and bladder. When I was informed about the injection, I read about its effects, so I'm not surprised, but it doesn't make me feel any less miserable. I experience severe hot flashes day and night, weight gain, and a severely decreased libido. Fortunately, I haven't felt any joint pain yet, but I hope I never do. I'm scheduled for the second dose, but I'm on the fence about continuing due to my decreased libido and weight gain. This injection is affecting my self-esteem, but I can't handle being in pain for 13 days every month. Although I still had a period every month, my last one was the worst, with heavy bleeding, extreme bloating, and gastrointestinal pain. If you're informed about this injection, choose to use it wisely."

4 / 10
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  • Flo...
  • July 22, 2014

For Prostate Cancer "Hot flashes and chills. Stomach became larger and weight gain. Hot flashes are very annoying. Fainted, and the doctor said it probably was due to dehydration."

8 / 10
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45 Report
  • Sul...
  • November 20, 2015

For Uterine Fibroids "This medicine has given me horrible headaches. Lost a lot of hair, gained weight, insomnia."

1 / 10
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23 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.