Lupron Depot and Weight Gain: What Users Say (Page 2)

• fat...
• Taken for 1 to 6 months
• June 1, 2023

For Prostate Cancer "Tried Lupron Depot every 3 months two times, but severe fatigue, occasional dizziness, and passed out. Side effects were not acceptable to me. Orgovyx + Xtandi is much better. Although, without testosterone: fatigue, no erection, lack of enthusiasm, and weight gain."

• Mik...
• Taken for 1 to 2 years
• January 13, 2025

For Prostate Cancer "Overwhelming, suffocating hot flashes that cause instant full-body sweating. This has caused disruption to all aspects of each day (whether at work, at leisure time, or bedtime). This drug causes weight gain regardless of exercise intensity. It has completely stopped all sex drive or interest. It has caused genital shrinkage and, at times, discomfort. I have unusual fatigue and muscle atrophy. I have been getting the drug for a year and a half. I will not be able to tolerate any more of this drug. It has kept my testosterone level at near undetectable levels."

• Bru...
• Taken for 1 to 6 months
• December 26, 2024

For Prostate Cancer "I am taking this drug along with 10 mg of Prednisone, so some of my symptoms may be from either drug. I've been taking Lupron Depot for four months and the prednisone for eight months. Hot flashes, 15-20 per day. Lasting 3-4 minutes. Dizziness, but much better since I stopped taking Flomax. Weight gain, always hungry. Prednisone does this to me. Fainting, may be dehydrated at times. A bit of chest pain, but not serious."

• Ano...
• Taken for 1 to 2 years
• May 19, 2025

For Prostate Cancer "I've been taking it for over a year and noticed a pronounced sadness and depression that wasn't there before. I am an adult male. I also have weight gain even though I exercise. I have to force myself to do things. My PSA and testosterone have come down to almost zero."

• End...
• Taken for 1 to 6 months
• April 27, 2023

For Endometriosis "I am a 22-year-old Black woman who started taking this injection in February after undergoing diagnostic surgery for endometriosis. I don't know what stage of endo I'm in, but it has spread to my intestines, liver, ovaries, and bladder. When I was informed about the injection, I read about its effects, so I'm not surprised, but it doesn't make me feel any less miserable. I experience severe hot flashes day and night, weight gain, and a severely decreased libido. Fortunately, I haven't felt any joint pain yet, but I hope I never do. I'm scheduled for the second dose, but I'm on the fence about continuing due to my decreased libido and weight gain. This injection is affecting my self-esteem, but I can't handle being in pain for 13 days every month. Although I still had a period every month, my last one was the worst, with heavy bleeding, extreme bloating, and gastrointestinal pain. If you're informed about this injection, choose to use it wisely."

• Flo...
• July 22, 2014

For Prostate Cancer "Hot flashes and chills. Stomach became larger and weight gain. Hot flashes are very annoying. Fainted, and the doctor said it probably was due to dehydration."

• Sul...
• November 20, 2015

For Uterine Fibroids "This medicine has given me horrible headaches. Lost a lot of hair, gained weight, insomnia."