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Hylan g-f 20 and Swelling: What Users Say (Page 2)

Brand names: Synvisc, Synvisc-One

Reviews for Hylan g-f 20

Commonly mentioned side effects
  • Anonymous
  • December 4, 2016

For Osteoarthritis "Acute pain and swelling 6 hrs after the injection, unable to walk, difficult to sleep. Can't bend my knee and in absolute agony. Day 5 and my entire life is on hold as it is very difficult to move, wish I would never have had the shot - dangerous!!"

1 / 10
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24 Report
  • Pur...
  • Taken for less than 1 month
  • September 27, 2018

"I had the Synvisc injection, and exactly 30 days later, my knee was swollen. Couldn’t bend, drive, barely walk. Dr. ordered an MRI, it was clear. Doctor drained my knee and said it was an allergic reaction to this gel injection. Started to swell again within the hour of having it drained. Called his office and was told this can happen and to just stay off my knee. Ice, ibuprofen. I just don’t understand how I can get an allergic reaction to something that’s been in my body for 30 days. This was a mistake, I should have never tried this."

1 / 10
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15 Report
  • pre...
  • Taken for 1 to 2 years
  • May 13, 2019

For Osteoarthritis "I will never do Synvisc-One again. First injection got mild flu-like symptoms. Some pain relief, a little better movement, and some swelling for about 2 months. Six months later, I got the second injection, got flu-like symptoms again, only much worse, along with swelling in my knee and no pain relief. Cortisone injections to help counteract the second injection only lasted about a month."

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  • Anonymous
  • September 11, 2015

For Osteoarthritis "Extreme pain and inflammation on the site where the injection was done. It happened in my first and now my second set of injections. The swelling lasts for about a week. I will not be getting my 3rd set of Synvisc injections. Too painful."

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21 Report
  • Anonymous
  • September 11, 2015

For Osteoarthritis "Extreme pain and inflammation on the site where the injection was done. It happened in my first and now my second set of injections. The swelling lasts for about a week. I will not be getting my 3rd set of Synvisc injections. Too painful."

1 / 10
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21 Report

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  • Min...
  • Taken for less than 1 month
  • October 25, 2018

For Osteoarthritis "I have had OA for many, many years. Have bone on bone with one cleanup 20 years ago. Yes, I need replacements but trying to hold off. I had cortisone, and they lasted maybe a month. Three weeks and one day ago, I had Synvisc-One injections. Yes, they hurt. Yes, the left knee was swollen and painful. But...I woke up this morning, three weeks and one day since my injections...wow!! The pain has been reduced immensely. I can't say how excited I am! The doctor suggested I have a cortisone booster in January...I can do that!!!! I've read comments that some shots lasted 6-9 months. I'll take that. I am a caregiver for my husband, and now I have some relief!!!"

9 / 10
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  • big...
  • August 25, 2016

For Osteoarthritis "After having a few cortisone shots and not much luck or longevity with them, my Dr. asked me to try the Synvisc-One, and I was reluctant at first, but when you have 100% bone on bone in one knee and 75% bone on bone in the other, I was willing to try anything. I had to wait also to be approved by Wellness Blue Cross Blue Shield. It was finally approved, and I had the shots in late July. I'm 49 years old and a bigger, heavier man, and I made my 15-year-old son come in to watch. It hurt like heck. My son was shocked to see me wincing in pain the entire time. It takes a little while to get it all in your knee as well. Then to my other knee, I gripped the table and said my god, nobody said they were this painful. Swelled up so bad for a week. Never helped me."

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  • Gin...
  • April 13, 2021

For Osteoarthritis "Had the Synvisc injections (3) a year and a half ago with success. Was able to move my knee joint freely and returned to exercising. In the last 2 weeks, pain, stiffness, and swelling have returned to the same knee. Was given a steroid shot after excess fluid was drained. Some help, but not like the Synvisc shots. The orthopedic doctor tells me they are no longer covered by my insurance!"

10 / 10
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  • Bab...
  • March 19, 2018

For Osteoarthritis "After reading the reviews of those who have had the Synvisc shots, I am surprised at the level of pain some are describing. My ortho doc did tell me that some people don’t react well, that their knees “blow up,” especially after the 4th or 5th time, and if that were to happen, to come right back. Maybe I am just lucky - no bad reaction, just pain free. It takes about 4 weeks for the injection to take full effect. My first shot of Synvisc One was in May 2016. It was not painful to have the shot, as my rheumatologist also used some local anesthesia with it. Within a month, I was pain free in my knee. I previously was wearing a brace on my knee. Since then, I have had the shot every 6-8 months in my left knee (from my ortho doc). I occasionally have a “little” pain if I overdo things, but it goes away once I rest for a bit. I’ve had the shot 4 times now; just a couple days ago was the last time. Only a tiny bruise at the site, and very slight swelling. That’s it. Worth it not to have pain for 6-8 months."

10 / 10
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  • Joh...
  • January 23, 2021

For Osteoarthritis "The first Synvisc injection I had pain, but the second has been excruciating! I can’t walk without crutches (because that’s all I have for assistance). My knee is swollen and very painful to walk. Cannot get comfortable no matter what I do and cannot sleep! Taking ibuprofen and Tylenol, but no relief! Not doing another injection!"

2 / 10
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  • Did...
  • Taken for less than 1 month
  • September 10, 2017

For Osteoarthritis "I had my first shot of Synvisc in my right knee in February 2016, as it kept clicking/popping due to OA. Found the first shot to be amazing. Was walking normally the next day. Six weeks later, decided to have my left knee done. Again, amazing, I could walk without any problems. Six to seven months later, I had both knees done at the same time. Lost some weight, rode the exercise bike, and walked a lot. This time, I had nine months of relief. Went back for a third round. Had Synvisc in my right knee and another product in my left. No problems with my left knee, but my right knee swelled up and had to be drained (twice). I had obviously built up a sensitivity to it. My right knee is back to clicking/popping every couple of steps, which is really annoying."

7 / 10
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10 Report
  • Anonymous
  • Taken for less than 1 month
  • September 14, 2017

For Osteoarthritis "I have severe arthritis in my right knee. I had arthroscopic surgery 20 years ago, and now I am in need of a knee replacement. I have been getting cortisone injections and thought I might try Synvisc. I had the first injection Monday, September 11, and the next day I had swelling and severe pain. I have been in pain since, I can barely walk. I didn't know I had this kind of pain before I had this injection. And due to get another one Monday, but I'm not going to do it, I'm in too much pain, it's not worth it!"

2 / 10
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  • Wob...
  • Taken for 1 to 6 months
  • April 15, 2018

For Osteoarthritis "Bottom line - I think the Synvisc One really helped the knee joint function, but the side effects for me were so bad I will never use it again. Severe osteoarthritis in both knees. Had Synvisc One injections in both knees early Dec 2017. The injections were brutally painful - and I’m not normally bothered by pain. Not sure I could bring myself to do it again. I was barely able to walk for 3 days, then developed constant, deep aching pain, swelling, and stiffness in both legs from toes to hips that did not respond to ibuprofen or lidocaine patches. Ended up having steroid injections twice to control the side effects. After the last one, I lost 6 lbs in 2 days, fluid out of my legs. Now it is mid-April 2018 and I can tell the side effects are becoming less - and the mechanical knee joint pain and instability are returning. It’s too bad that I experienced such severe side effects because I think the Synvisc was actually very effective with the joint mobility and pain."

6 / 10
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  • Blu...
  • Taken for 1 to 6 months
  • June 23, 2023

For Osteoarthritis "The Synvisc One injections have made my knee pain a little better, but I am now having severe stiffness in my calves, foot pain, swelling, and numbness I did not have until after the shots. It is about 7 weeks post-injection. (The first 3-4 weeks were the absolute worst). I will not have them again and hope the injections will wear off in the next 4 months and my legs/feet will return to normal. I am considering seeing a different Ortho doctor and praying for a better solution!"

3 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 14, 2022

For Osteoarthritis "I wish to God I had never consented to having this medicine injected in me. I am 49 years old and suffer with mild osteoarthritis in my right knee. My nurse practitioner (NP) strongly suggested this med. I read the pamphlet, which in hindsight was more of an advertisement for the drug instead of unbiased information. I wish I had done more research on this drug. I was to receive a series of 3 injections. Nothing much happened after the first injection, but after the second injection, my knee became swollen, stiff, and very painful. I couldn't bear weight on my right foot without extreme pain. I contacted my NP, who apparently thought I was exaggerating or simply had no experience with adverse reactions to this drug. Well, after begging to be seen, she finally realized it was serious. I ended up having my knee drained and given a cortisone injection. Unfortunately, that only relieved the pain slightly. The pain and swelling eventually returned. Please do your research."

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  • Fed...
  • Taken for less than 1 month
  • July 21, 2021

For Osteoarthritis "I had a pseudo-septic reaction to Synvisc. I had it injected bilaterally in my knees. One week later, I had 60cc of fluid drained from both knees and had cortisone injections bilaterally. That night, simply rolling over caused a tear due to the instability of the joints from the edema. I underwent yet another scope. This was back in 2008!"

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  • Car...
  • Taken for 1 to 6 months
  • June 19, 2019

For Osteoarthritis "I had a great experience. No pain. A little swelling, but that is all. I will do it again."

10 / 10
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  • lil...
  • Taken for 1 to 6 months
  • July 10, 2021

For Osteoarthritis "It did not work for me at all. Today, after 3 months, I am actually worse than before using it. My knee is swelling, and I have a hard pain even sleeping. I don't recommend it at all."

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.