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User Reviews for Fluticasone / salmeterol to treat Asthma, Maintenance

Also known as: Advair Diskus, Wixela Inhub, Advair HFA, AirDuo Respiclick, AirDuo Digihaler

Fluticasone / salmeterol has an average rating of 4.5 out of 10 from a total of 186 ratings for the treatment of Asthma, Maintenance. 36% of reviewers reported a positive experience, while 55% reported a negative experience.

Fluticasone/salmeterol rating summary

4.5/10 average rating

186 ratings from 200 user reviews.

Compare all 73 medications used in the treatment of Asthma, Maintenance.

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Reviews for Fluticasone / salmeterol

Short of Breath · Taken for less than 1 month · September 27, 2021

Wixela Inhub (fluticasone / salmeterol): “I was recently taken off Symbicort and it was replaced with Wixela. The VA changed to this medication most likely due to cost effectiveness. I gave it to weeks to work and a couple of times after doing it within one hour and a half I was actually gasping for air. There’s never happened on Symbicort. My physical activity has been reduced to almost nothing where before I could get in at least 6 hours of light physical activity in daily. I have used my rescue inhaler more times in the last two weeks than I have for the first eight months of 2021. It is so sad when your quality of life is robbed because it’s too expensive to give it to you.”

1 / 10
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Anonymous · September 17, 2021

Wixela Inhub (fluticasone / salmeterol): “Was on budesonide for 5 years It worked great!. Then somehow the prices got jack up of meds that work, so insurance won't cover it, the VA wont cover it and Medicare are wont cover it. This WIXELA CRAP is dumped on the poor, the veterans and the unrepresented by congress. I want my Budesonide. I emailed Maggie Hassan. She says shes for the vets. Actions speak louder than words.”

1 / 10
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Chuck · October 17, 2020

Wixela Inhub (fluticasone / salmeterol): “Absolute garbage! I was switched over from Advair a week ago. My asthma has been completely under control for years with Advair. After one week of using this my chest gets tight a couple hours after using it and I have mucus building up in my lungs that causes me to cough and hack all day. I’m actually better off just not taking any medicine at all. How did this drug get approved?”

1 / 10
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wixela inhub · Taken for 1 to 6 months · October 5, 2021

Wixela Inhub (fluticasone / salmeterol): “I was switched to Wixela from symbicort within the VA. Does nothing for me except a sore throat . I engaged it to work and tapped it on a clean flat surface and the powder feels like a gritty fine powder or sand. I think it ought to be removed from market .Don't know how the VA was sold on this terrible product. Want my Symbicort back that works for my lungs.”

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LT · Taken for 1 to 6 months · March 6, 2021

Wixela Inhub (fluticasone / salmeterol): “Terrible! Insurance just changed formulary adding wixela inhub, dropping advair for what they'll cover. I noticed a difference within a week, needing to use my albuterol inhaler nearly daily now when before hardly ever. I have a lot of mucus now when I didn't before. Everyone should be complaining to the FDA and their state insurance commissioner. Insurance companies should NOT be able to cover only cheaper drugs when they don't work and the FDA should require this drug is taken off the market. Horrible.”

1 / 10
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Leh · January 2, 2020

Wixela Inhub (fluticasone / salmeterol): “So first off check your expiration dates. Noticed my inhalers were only good for 5 or 6 months from pharmacy pick up to expiration. Advair was always a year. Somethings wrong with that. Next I switched to Wixela due to Advair being over 400.00 to fill. The medication delivery was poor. Never felt much relief. Started getting tight more, coughing more, had frequent exacerbations and was put on prednisone, nebulizer treatments etc. I have not had to do that in close to 10 years. This drug is worthless! Back to Advair even though I'll have to get a second job just to pay for it.”

1 / 10
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Victoria b · Taken for 1 to 6 months · June 5, 2021

Wixela Inhub (fluticasone / salmeterol): “I was switched to Wixela in last three months and since then I have been getting sicker. I now have cold sweats irregular heart rate pounding heart worsening asthma symptoms three bouts with bronchitis chronic cough and having to use albuterol when my asthma was well controlled for 10 years . Wixela needs to be removed from the market”

1 / 10
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Frequently asked questions

Kaj · Taken for 1 to 6 months · September 24, 2019

Wixela Inhub (fluticasone / salmeterol): “My asthma was well under control until I was forced by my insurance company to use Wixela three months ago. Now, I have a chronic cough again, it's affecting my vocal chords and I feel like an elephant is sitting on my chest several times a day. I'm using my rescue inhaler all day long (I was using it MAYBE twice a month), cough medicine 24/7, sleeping practically sitting up, and buying/using cough drops like they're going out of style. But to go back to my original inhaler, I'll have to fork over $300 more per month (four months ago it was $40/month). The problem is 1) big pharma 2) insurance companies putting profits before health and 3) the device used to dispense the Wixela may be flawed. There is no way I am receiving the dosage I am prescribed.”

1 / 10
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Dave · Taken for 1 to 6 months · August 13, 2020

Wixela Inhub (fluticasone / salmeterol): “After reading bad reviews, I gave Wixela Inhub a chance for a couple of months and I have to agree with the reviews. The dispenser itself is poor and causes the powder to get all over the back of my throat and tongue instead of into my lungs, and I’ve been coughing and wheezing a lot more on Wixela than I did on Advair. I’m not gambling with my health anymore so that my insurance company can save money anymore and I’m going back to Advair. You should too.”

4 / 10
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Meadow8888 · Taken for less than 1 month · October 5, 2020

Wixela Inhub (fluticasone / salmeterol): “I had just recently been put on Wixela Inhub like everyone else who was on Advair. I have been taking Advair for many years having NO side effects at all, and it working very well for my asthma. As soon as I started using the Wixela Inhub I started to get severe heart palpitations/racing and after only a couple of days had to stop taking it!!! WAY too dangerous!! My pharmacist said that if my Doctor fills out an "adverse side effect form" on it etc.... that he will be able to put me back on Advair, and it still be covered!! By the comments here and how I feel from the Wixela Inhub, it should be taken off the market!!”

1 / 10
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Engineer · Taken for 1 to 6 months · December 21, 2019

Wixela Inhub (fluticasone / salmeterol): “I agree with the comments. After 2 months on Wixela I am having severe problems with my asthma. 10 years on Advair with no problems. I too believe the dispensing mechanism is defective since the active ingredient must remain the same by law.”

1 / 10
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BriM · Taken for 1 to 6 months · November 2, 2020

Wixela Inhub (fluticasone / salmeterol): “This Wixela Inhub inhaler does not work at all and I think the problem at least with mine is no powder is coming out. Like others the first few times it spit a gross amount of powder in my mouth but after about 10 uses that stopped and now zero powder is coming out. I think it's a double edged sword; if powder comes out, it comes out in a consistency that is too big doesn't penetrate into the lungs. When it stops doing this nothing comes out which it's probably clogged but there isn't any way to take it apart and clear a clog like you can with aerosol inhaler.”

1 / 10
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WenInOh · Taken for 10 years or more · December 1, 2019

Advair Diskus (fluticasone / salmeterol): “I have used this medication for about 20 years give or take a year or so. It works, I guess, though I am finding out, more and more it is contraindicated with many meds I take. The price is ABSOLUTELY RIDICULOUS! Most especially for seniors on Medicare Part D where, when in the donut hole, or at the beginning of the year, are expect to pay WAY over 300.00! WHO has that kind of money at the first of the year when they are 70, disabled and on Social Security (unless have a very high income)? This diskus w/ meds and equipment amounts to a plastic disk and 60 little packets of power that can't be an eighth tsp of medication probably costs GSK a whopping 10 cents! RIDICULOUS and just WRONG!!”

2 / 10
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Sick and tired · Taken for 5 to 10 years · August 27, 2020

Wixela Inhub (fluticasone / salmeterol): “After using Advair for years, I was given a wixela prescription. Within a month of using, I now sound like I did years ago before treatment began. Cough, irritation to the throat, and mucus. Had none of these with advair. Insurance won’t pay for advair since the generic is available and the generic is making me more sick. There has to be something we can do!!”

1 / 10
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MB · Taken for less than 1 month · May 8, 2020

Wixela Inhub (fluticasone / salmeterol): “Wixela is the worst!! Given Wixela for asthma maintenance at the worst of times (Pandemic). Every thing you fear about Covid 19 are just about the same side effects as Wixela. I couldn’t stop coughing and have never had so much phlegm in my throat. I was horrified! Suffice to say, after taking Wixela for 3 weeks in the month of March, I stopped as it was the only new thing I introduced to my body and 2 days after stopping, cough and phlegm disappeared completely. If it wasn’t for my wife not getting sick, I would’ve thought I was infected with the Virus”

1 / 10
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Cocoacontessa · September 15, 2020

Wixela Inhub (fluticasone / salmeterol): “I am a 50 yr old female-no health issues other than occasional mild asthma from air quality/high pollen count issues. I’ve used Advair as a maintenance inhaler for years with no problems. I developed cough variant asthma right in the height of COVID. The pharmacy switched me to Wixela without even telling me-didn’t know until I opened the bag. Used it for 2 months and developed the worst raw/sore throat of my life, heavy chest pressure and rapid heart beat (could feel my heart pounding). Stopped using Wixela 4 weeks ago and the sore throat and chest pressure have gone away but my heart beat is still rapid-I can feel it when I’m in bed falling asleep! Now my doctor has ordered a stress test etc to figure out what’s going on with my heart. Stay away from Wixela!! This is a very dangerous drug!!”

1 / 10
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thed · April 17, 2020

Wixela Inhub (fluticasone / salmeterol): “I've been using Advair for years and what a relief as it worked great. I switched to the generic three months ago and have progressively been getting worse. This last month was terrible. I'm going off to see if another medication gets me back to where I was. I'll report results later. My condition seems consistent with others on the generic. Does not seem to work. Dangerous.”

1 / 10
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Marg · Taken for 1 to 6 months · October 13, 2020

Wixela Inhub (fluticasone / salmeterol): “I was using Breo for years, thankfully because there was a coupon. Otherwise, my insurance would never cover it nor could I afford it. The coupon was discontinued during the pandemic (of course!), and I could not afford to purchase it even with some insurance coverage. My doctor prescribed Wixela, and it is basically worthless. It requires two inhalations a day vs. Breo's one, the inhaler itself is strangely designed, and I can feel the powder all over my tongue. The biggest issue is that I cannot breathe. One puff of Breo and I was out running five miles. With Wixela, I am gasping for air.”

1 / 10
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CC · Taken for 1 to 6 months · June 17, 2020

Wixela Inhub (fluticasone / salmeterol): “I had to switch to generic due to insurance. I started using this a month ago and found my symptoms have increased. I have a lot of phlegm, and coughing a lot. Due to the cough, I am sleeping less and feel tired during the day and very little energy. I have a call into the doctors to send a script for Advair 250/50 and will have to pay the high cost.”

1 / 10
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Sick · Taken for less than 1 month · January 26, 2021

Wixela Inhub (fluticasone / salmeterol): “This medication is bad. It should be taken off the market. I got so sick on this. I got a very bad headache, racing heart beat, and thrush, it made me nervous. I just felt really bad. The medication does not come out right - you either get too much medication or none at all it does not get into the lungs, it just stays in the back of the throat and that is how I got the thrush. My doctor now has it so the prescription is dispense as written so the Pharmacist will now fill it with the Advair thank goodness. Like I said Wixela Inhub should be taken off the market as it is dangerous. If I could I would give it a 0 rating”

1 / 10
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AT · October 10, 2020

Wixela Inhub (fluticasone / salmeterol): “Mild asthma patient, with everything under control using Advair Diskus 250/50. As with others, my insurance stopped paying for the brand name and had to switch to Wixela. My symptoms went from non-existent (with Advair) to bad to worse. Stopped taking Wixela and things got better and I only had regular(!) asthma. Paid out of pocket for the Advair and everything was wonderful again. One year later- Chest pain is better, but not like it used to be. I now need a higher dosage of Advair than ever before, I will need to pay $4,000 a year for it, but it keeps me healthy. FDA should do something.”

1 / 10
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Jenny · Taken for 1 to 6 months · January 12, 2021

Wixela Inhub (fluticasone / salmeterol): “This is the worst inhaler I've every used. I was forced to switch to this due to insurance not covering name brand. I've had nothing but problems breathing since I started taking it. I've been fighting constantly with the insurance to cover the name brand, even at a higher price but it's super difficult. How can they still sell this stuff, it's horrible.”

1 / 10
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Scared · Taken for 1 to 6 months · December 10, 2020

Wixela Inhub (fluticasone / salmeterol): “Please don't use this drug Wixela Inhub. I started using Wixel 2 months ago. I'm always afraid of new medicine so I started taking it at 2 puffs a day for my asthma. I developed sore throat, headaches, voice hoarse, then heart racing. I have a neurological illness as well so I thought it was the problem. 3 weeks ago I had a possible TIA (ministroke). I'm only 55. Lost sight totally in my left eye for hours with increased weakness and headache. Today I thought to look into this inhaler for side effects. Then checked the reviews here . I won't ever use this again. I need to live to care for my daughter. This medication shouldn't be on the market.”

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Moonstar · Taken for less than 1 month · May 26, 2020

Wixela Inhub (fluticasone / salmeterol): “Inhub dispenser is awkward don't feel like I get same dosage as Advair. Makes me tired, post nasal drip, and on and off cough. Makes me anxious that I'm not getting enough med and fear an attack. Don't want to get sick especially with Covid19 about. I'd rather have Advair HFA”

2 / 10
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Bell · Taken for 1 to 6 months · April 8, 2021

Wixela Inhub (fluticasone / salmeterol): “I have used advair for many many years - it works great! Now they have switched me to Wixela, and I am constantly out of breath and using my rescue inhaler all the time. -- it is a miserable substitute!!!!”

1 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.