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Zetia User Reviews & Ratings (Page 3)

Zetia has an average rating of 4.3 out of 10 from a total of 77 reviews on Drugs.com. 30% of reviewers reported a positive experience, while 57% reported a negative experience.

Reviews for Zetia

Commonly mentioned side effects
  • Hap...
  • Taken for 1 to 2 years
  • May 7, 2025

For High Cholesterol "This medicine was fine until I had to take a hormone cream. The pain in my shoulder, arm, and spine was terrible. This was at Christmas. Couldn't get to a doctor. Rang pharmacist, he said it was not the cream. Waited three weeks, went to a physio, cost £100 pounds. Rang pharmacist again, told him he said to stop taking Zetia, this would exacerbate the pain, so stopped just after Christmas. Just tried again two weeks ago, pains all over, so stopped again. Waiting for the pains to stop. Never again."

8 / 10
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3 Report
  • Mel...
  • Taken for 1 to 6 months
  • August 5, 2024

For High Cholesterol "8/2/24 My experience with Zetia has been unexplainable. My numbers were very high, and now, after being on it for 3 months, they are very low. So low I had my doctor do another blood test because I thought the test results were wrong. The second test, done a week later, was even lower. Now I am concerned they will get too low. All statins I was put on caused severe cramping: arms, legs, feet, hands, under my rib cage, back. The only side effect I have with Zetia is possible cramping in my forearms when I stretch and my calves. I also have had hair loss. Now taking Rogaine to see if that helps. I am 75 years old, so lots of complaints may be from just getting old."

10 / 10
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8 Report
  • Ezz...
  • March 25, 2017

"Was notified recently that the expensive drug Zetia now has a generic version called Ezetimibe, however, Zetia is a tier 3 drug and Ezetimibe is a tier 4 drug, which means I will be paying even more than before since my plan will no longer carry Zetia after June 1, 2017. Unbelievable!!"

5 / 10
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32 Report

Frequently asked questions

  • BMI...
  • Taken for 6 months to 1 year
  • May 4, 2024

For High Cholesterol "As with Zetia or statins, you must have a BMI of less than 29. If you are too fat or not continuing to get your BMI down to 25, you will not benefit. You can't just pop pills and expect magic if you continue to eat junk food and have a BMI of 30+. My BMI is 26, and 10mg of Zetia works with no side effects. I will add 20mg of a statin soon (not 40mg like crazy doctors prescribe). If your BMI is over 29, you will be lucky to live 5 weeks longer on meds. If your BMI is under 29, you may get 5 years longer. Exercise and diet are the key. There is no magic pill. If you don't care about living 5 years longer, then get off the pills and go smack down some more ice cream, candy bars, and Cokes. Any doctor that tells you any pills work without a better diet and more exercise is on the crack pipe and doesn't translate the scientific findings over the last 4 decades... Many doctors tell you how it really is, in that you need to lose weight. You are not listening to the most important part of the conversation."

10 / 10
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16 Report
  • fgr...
  • June 25, 2013

For High Cholesterol "I have been using Zetia for two years. I am also having extreme muscle pain with profuse sweating when I get too hot."

7 / 10
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145 Report

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  • Nun...
  • March 5, 2014

For High Cholesterol "Dizziness, tiredness, runny nose, sore throat, cough, diarrhea, generally feel bad."

2 / 10
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122 Report
  • Hei...
  • March 21, 2013

For High Cholesterol "Stopped taking Zetia at night as I had horrific nightmares. Will try it in the morning, see if I have any side effects. Can't take statins because of muscle pain."

3 / 10
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123 Report

More FAQ

  • gon...
  • Taken for less than 1 month
  • March 11, 2016

For High Cholesterol "Only took 2 days. Leg pains already, flu-like symptoms, felt feverish, but no fever. Cold, clammy chills. I can't take statins, and it seems this is a no-go also."

1 / 10
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101 Report
  • Anonymous
  • November 21, 2011

For High Cholesterol, Familial Heterozygous "I didn't get on with statins - muscle aches. I have been taking this for several years with absolutely no side effects, and my cholesterol level keeps my doctor happy."

10 / 10
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127 Report
  • Car...
  • April 20, 2013

For High Cholesterol "After starting Zetia, I began to have weird dreams which lasted throughout the night. I began taking it in the morning with my breakfast, and had stomach discomfort."

7 / 10
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115 Report
  • Emi...
  • Taken for 1 to 6 months
  • June 12, 2023

For High Cholesterol, Familial Heterozygous "Exacerbation of neck pain, fatigue, dizziness, extreme weakness in legs to the point of having difficulty walking. Took it for 4-5 months. Stopped it 4 days ago, mild improvement in leg weakness."

1 / 10
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29 Report
  • Ken...
  • June 15, 2013

For High Cholesterol, Familial Heterozygous "Taken for two weeks and have back pain. Stopped taking medicine."

1 / 10
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106 Report
  • Not...
  • October 22, 2015

For High Cholesterol "I took 1 Zetia and my throat swelled up. I wound up in the ER, getting IV steroids and Benadryl. I will never take it again. I cannot take statins due to terrible muscle pain."

1 / 10
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86 Report
  • sg3...
  • May 24, 2010

For High Cholesterol "Put my heart into A-fibrillation. It was discontinued, and no sign of A-fibrillation in the heart when checked."

1 / 10
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112 Report
  • ahi...
  • September 8, 2015

For High Cholesterol "I experienced severe abdominal cramps and pain, as well as diarrhea. I also experienced weakness and fatigue. I could not tolerate the drug, so I do not know if it had any effect on my cholesterol."

1 / 10
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67 Report
  • Anonymous
  • Taken for less than 1 month
  • October 5, 2015

For High Cholesterol "I am shocked at the out-of-pocket price of Zetia of $95.00 a month. Since this seems to be the only non-statin replacement for use with cholesterol, you are definitely price gouging."

1 / 10
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74 Report
  • Anonymous
  • July 14, 2010

For High Cholesterol "So far no muscle pain with this medication. Very expensive, over $100 for 1 month supply, and no generic."

6 / 10
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82 Report
  • Anonymous
  • September 2, 2009

For High Cholesterol "I have not had any bad experiences with this medicine since I started taking it. I am very pleased it is working so well for me."

9 / 10
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81 Report
  • Ste...
  • Taken for less than 1 month
  • August 19, 2023

For High Cholesterol "The safest medication to use. Stay away from statins, deadly medication like Crestor, Lipitor, etc. They can damage you for life. Zetia keeps my cholesterol and triglycerides in the normal range."

10 / 10
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16 Report
  • Liz...
  • Taken for less than 1 month
  • June 19, 2023

For High Cholesterol, Familial Heterozygous "Took for a week but had to stop because of painful gas!"

1 / 10
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17 Report
  • LSG...
  • Taken for 5 to 10 years
  • January 16, 2017

For High Cholesterol "Got my cholesterol under control and no adverse side effects. Cost is a bit high, but insurance pays about 66%."

10 / 10
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45 Report
  • Anonymous
  • Taken for less than 1 month
  • December 16, 2021

For High Cholesterol "Can't tolerate statins. My LDL is 136. My doctor wants me to try Zetia. It's been 6 days, and I feel horrible. Sick feeling and bad fatigue. Not good for me."

1 / 10
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20 Report
  • tom...
  • Taken for 1 to 6 months
  • October 30, 2020

For High Cholesterol "Started on Zetia on top of Crestor. Still taking it, but the vivid, wild, and bizarre dreams at night are awful. Wake up exhausted. I'll continue, but we'll see for how long."

5 / 10
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25 Report
  • dec...
  • March 31, 2008

For High Cholesterol "Cut my LDL in half when added in combination with Lipitor."

10 / 10
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78 Report
  • bra...
  • Taken for less than 1 month
  • February 8, 2021

For High Cholesterol, Familial Heterozygous "This caused flatulence and diarrhea, which don't make a good mix."

3 / 10
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22 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.