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Zetia and Tiredness: What Users Say

Tiredness: mentioned by 5 users (6.7%)

Based on user experiences from 75 Zetia reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

muscle pain 14.7%
fatigue 13.3%
pain 13.3%
sweating 13.3%
cramps 12.0%
diarrhea 9.3%
joint pain 8.0%
chills 6.7%
tiredness 6.7%
weakness 6.7%

Reviews for Zetia

Commonly mentioned side effects
  • Fre...
  • Taken for less than 1 month
  • November 13, 2019

For High Cholesterol "I cannot take statins as they tank my depression. I am a disabled veteran and have had my depression under control for several years now. My general practitioner at the VA put me on Zetia for cholesterol. I took it for approximately 4 days. My depression got so bad that I stopped it today and notified my psychiatrist and my general practitioner that I was stopping it as of today. I spent the last two days crying because I felt so bad. I also was extremely tired, and my joints and muscles were hurting. This is just how the statins affected me. If you suffer from depression, run away from this drug as fast as you can!! It works very quickly and can catch you completely off guard!"

1 / 10
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460 Report
  • one...
  • Taken for 1 to 6 months
  • April 18, 2018

For High Cholesterol "Couldn't take statins due to multiple side effects. Took Zetia for 6 weeks before realizing it was causing severe nausea on a daily basis, constipation, extreme tiredness, excruciating hip pain, hot flashes with profuse sweating, as well as gastritis. I've been off Zetia for two weeks and I'm still having the awful sweating flashes, constipation, hip pain, and tired to the point I fall asleep for about 30 minutes when I get home from work every day. The nausea is finally gone and gastritis has improved. I hope all this goes away soon!! I'm miserable! I will not take meds for cholesterol again. I'm going to go back to Krill oil and flaxseed oil."

1 / 10
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218 Report
  • bob...
  • Taken for 6 months to 1 year
  • December 17, 2020

For High Cholesterol "I started taking Ezetimibe in Feb. 2019. I cannot tolerate statins. After 10 months, I started to develop joint pain, muscle weakness, a runny nose, and was very tired. I checked my blood pressure. It was 213 over 120. I decided that Ezetimibe could be the problem. I stopped taking Ezetimibe. After 2-1/2 days, my blood pressure dropped to 152 over 94. I feel 100% better. There is a question that my liver could have been damaged."

1 / 10
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32 Report

Frequently asked questions

  • Nun...
  • March 5, 2014

For High Cholesterol "Dizziness, tiredness, runny nose, sore throat, cough, diarrhea, generally feel bad."

2 / 10
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120 Report
  • tom...
  • Taken for 1 to 6 months
  • October 30, 2020

For High Cholesterol "Started on Zetia on top of Crestor. Still taking it, but the vivid, wild, and bizarre dreams at night are awful. Wake up exhausted. I'll continue, but we'll see for how long."

5 / 10
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25 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.