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Does Zetia affect blood pressure?

Medically reviewed by Melisa Puckey, BPharm. Last updated on Nov 1, 2023.

Can Zetia raise blood pressure? Can Zetia cause high blood pressure? Can Zetia cause low blood pressure?

Official answer

by Drugs.com

Zetia does not affect blood pressure. In clinical trials Zetia did not increase or decrease patients' blood pressure.

Some people may have already been diagnosed with hypertension (high blood pressure) before they start taking Zetia. If you do have high blood pressure and you are on medication to control it, then it is important to treat both high blood pressure and high cholesterol, so you reduce your cardiovascular risk.

Talk with your doctor about the medications you are taking and whether they are compatible with any new medications that you may be starting.

References

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Does Zetia (ezetimibe) cause memory loss?

Memory loss is not a side effect of Zetia (ezetimibe) when it is used alone to treat high cholesterol. Zetia is often used with diet and other cholesterol lowering medications like statins which have been linked with cognitive impairment (memory loss, forgetfulness, or confusion). Continue reading

Can Zetia (ezetimibe) cause liver damage?

Yes, Zetia (ezetimibe) can cause liver damage, although it is very rare. Monitor liver enzymes for the development of serious toxic hepatitis and consider ezetimibe discontinuation if it develops. Perform liver tests during ezetimibe initiation and regularly thereafter and consider withdrawal of ezetimibe and/or the statin (if coadministered) should an increase in ALT or AST ≥3 X upper limit of normal (ULN) persist. Continue reading

How does Zetia (ezetimibe) work to lower cholesterol?

It reduces cholesterol absorption from the small intestine so there is less cholesterol delivered to the liver. This means there is a lower amount of cholesterol stored in the liver, which leads to more cholesterol being cleared from the blood. Continue reading

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