Repatha and Weakness: What Users Say (Page 2)

• Ste...
• Taken for 1 to 6 months
• October 21, 2017

For High Cholesterol "I am 69 years old. I have been an athlete all my life and have run over forty thousand miles. I do not tolerate statins due to severe muscle pain. I was walking 6 miles a day prior to taking Repatha. After three shots of Repatha, I developed debilitating pain and weakness in my back and right leg. 9 on the pain scale. I still, three weeks later, have difficulty walking. It seems to be improving somewhat, with better days followed by a more difficult day. This has had a terrible impact on my quality of life. DO NOT TAKE this drug!"

• Min...
• March 8, 2019

For High Cholesterol "My mother took Repatha. If you are taking this medication, watch for memory loss, having a hard time walking, anything not normal. This medication just about killed my mother. From heart problems to liver. Her memory confusion started mild, along with the walking problems. She went from walking on her own to a cane to a walker. She is 3 weeks from the last shot, and finally, she can walk with the walker again, and yet she had been really bad last month and a half. Thought we were going to lose her. Please be careful with Repatha."

• Vic...
• October 8, 2018

For Cardiovascular Risk Reduction "I can't take statins. My doctor prescribed Repatha to me and confirmed to me that it has no side effects. I took 3 injections. I started feeling muscle pain and back pain. I felt very weak and fatigued. I checked with my doctor and pharmacist. They said that Repatha is causing these problems. I wish I never took Repatha. I wish someone could tell me how long I have to wait to feel better and get back to normal conditions. It has been 2 weeks since I took my 3rd injection. I recommend that you don't take this drug. It's dangerous. I don't know what to do now."

• Joe...
• Taken for less than 1 month
• November 11, 2022

For High Cholesterol "I had terrible experiences with statins, so my cardiologist suggested Repatha. I've had one dose and I'm done! I feel weak, feel like my head is in a fog, and have lost the vigor for life I had before I took this. My personality is blunted, as if I'm perpetually in need of sleep. I can't sleep all night anymore. Can't think clearly. I've never had a heart attack, but my doctor put me on this. According to the research, this only prevents 1 out of 100 heart attacks after 2.5 years of use. There's no way I'm going to take this again. I'll lose weight, watch my diet, exercise, and take my chances because this is a case where the supposed cure is worse than a 1 in 100 chance of getting the disease. Do your research about anti-cholesterol drugs."

• Jur...
• September 25, 2019

For High Cholesterol "On Repatha for 2 years. Developed peripheral neuropathy, tremor, visual disturbances, intractable diarrhea, and muscle weakness on one side so profound that I could not lift my foot and needed a cane. Doctor found no other explanation. Off now for 4 months - neurological and gastric effects remain. Effective at lowering cholesterol, but at what cost?"

• dre...
• Taken for less than 1 month
• August 1, 2019

For High Cholesterol "Received 2nd dose on 14-day injection program, and 10 days after 2nd dose experienced severe reaction to Repatha. Adverse symptoms were dizziness, lightheadedness, headache, severe intestinal distress, body aches, burning skin sensation in upper body, pounding heartbeat, malaise, general weakness, chills, increased BP and heart rate. Adverse symptoms lasted 4 days before gradually subsiding to mild body ache and tiredness."

• del...
• Taken for less than 1 month
• August 23, 2018

For High Cholesterol "This drug is horrific. I have developed diarrhea, back pain, bloody, watery stool, sick at my stomach, weakness, and flu symptoms. You name the side effect - I got them. I'm coughing so hard I poop myself. Do not take this vile stuff... I give it a 0."

• Bri...
• March 15, 2018

For High Cholesterol "After taking Repatha for several months and developing intense neck and shoulder pain, I discontinued the medication for several months. The pain got better. My doctor convinced me to try it again. After two injections, I developed extreme muscle weakness, pain in my shoulders, knees, rash, sinusitis. After an extremely embarrassing experience at Disneyland where I couldn't get out of the Matterhorn ride because I had absolutely no strength in my legs, I discontinued Repatha. I will never take it again. Extreme pain and muscle weakness vs high cholesterol. I'll take my chances with the high cholesterol."

• dix...
• Taken for 1 to 6 months
• January 22, 2022

For High Cholesterol "First, let’s discuss their autoinjector. I’ve given injections for years as a nurse and administered to myself with less pain and bruising. I would much prefer to draw up the medicine and do it myself. The autoinjector needs a complete redesign. It is terrible. Now for Repatha. I’ve been on this for four months every two weeks. According to my doctors, it’s the wonder drug for lowering cholesterol. Maybe so, but its side effects are so bad your life isn’t so wonderful. Seriously, the fatigue, muscle weakness, nausea, lack of appetite. About four days after the injection, the real fun hits. It starts with chills and drenching sweats. Fatigue. Muscle weakness so that you can barely function. This is not a life worth living. I’ll deal with the high cholesterol and not being sick three weeks out of each month. I also have ulcerative colitis, and this drug is a trigger for flares. Every two weeks on Day 2, it flares and gets better about three days before the next dose."

• sai...
• Taken for 1 to 6 months
• July 27, 2019

For High Cholesterol "I took Repatha injections for 3 months. I then had weak, painful legs. I dropped my Harley. Leg pain for a month. Hard to walk. Went to Dr. for pain meds, which were not effective. Pain went to shoulders for a month. Could not roll over in bed, hard to get out of bed for a month. Pain went to hands and fingers, tried all pain meds sold OTC. Went to six Drs. Only a 10 mg hydrocodone and 4 aspirins would give me 4 1/2 hrs sleep. Fingers on fire. Had to doctor shop for opioids, did electro nerve test, back to Dr., gave me a shot in both wrists, almost painless Tulsa Dr., finally sleep all night! Carpal tunnel surgery on left hand in April, left hand is about 50%, weak, stiff, sore. Right hand healed up okay. About 90%. Heart Dr. and his nurse say no side effects. I take no other drugs. Mid-Nov. last injection, now end of July. Left hand still stiff, sore, weak eight months. Yep, had other symptoms also, raised BP, etc. Maybe permanent nerve damage."

• Bar...
• Taken for 6 months to 1 year
• March 20, 2018

For High Cholesterol "Since my doctor told me there were no side effects with this drug, I was convinced that my back pain, hip, and leg pain must be from some other problem. When the pain became so severe, I went to an orthopedist who took X-rays and couldn’t find any abnormality other than severe weakness in my left side and suggested I use a cane! Nothing helped with pain. I started developing hand weakness and even had trouble opening jars! I started to suspect that maybe my doctor was wrong, but he insisted that there were NO reports of these side effects with this drug. I stopped the drug anyway, and after 8 months of pain, my symptoms are subsiding! Hopefully, this drug has not caused any permanent damage."

• Sso...
• Taken for less than 1 month
• July 24, 2018

For High Cholesterol "Worst drug on the market. If I could give it a zero, I would! After 2 injections, I experienced extreme muscle weakness and joint pain. I discontinued the medication. Contacted the FDA, they informed me I was not the only person they had heard this from. I asked how long before the side effects were gone? This was March. They told me the end of May! It did get better. But recently, the muscle pain is back. It also grossly elevated my cholesterol after I discontinued the medication. I would not recommend anyone take this medication. The pros vs. the cons are just not worth it. I don't think they can give a 125 lb woman the same dose they give a 300 lb man and not expect side effects."

• Mel...
• February 20, 2017

For High Cholesterol, Familial Heterozygous "In September of 2012, I had triple bypass surgery, and in October of 2014, a stent to my left renal artery. I have coronary artery disease due to heterozygous familial hypercholesterolemia. I was on numerous statin medications, and they had nasty side effects. Additionally, they did not lower my LDLs to safe levels. My total cholesterol before my surgery was 300, with high triglycerides and LDL. Due to the high dosage of statin drugs, I had horrible myalgia, malaise, forgetfulness, protein in my urine, elevated blood sugar, and muscle weakness. After being on Repatha for 6 months, my cholesterol has been lowered by 70%. The only side effect from Repatha is stinging at the injection site. It is a miracle drug."

• Rep...
• Taken for 1 to 6 months
• August 24, 2022

For High Cholesterol "I started taking injectable Repatha for high cholesterol and high calcium score, and after the third injection, my quality of life went from a happy, active 66-year-old female to debilitated and depressed, going to many different specialists trying to find out what was wrong with me, never considering that it was side effects of my supposed new miracle medication that was going to give me a better chance of not having a stroke or heart attack! And I am a retired nurse! Not one doctor suspected the Repatha! I was so weak and uncomfortable and busy getting two runs of oral steroids for my back pain and seven weeks of physical therapy to think to check reviews. Finally, I made an appointment to see my cardiologist who prescribed it, and after the lipid panel, I went back again to discuss results, and I realized myself that my cholesterol (all types) had dropped significantly after five injections every two weeks, and I told the cardiologist that I wanted to stop Repatha to see if these symptoms would resolve, and finally, slowly, eight weeks later I’m better!!"

• Tax...
• February 2, 2018

For High Cholesterol "Not 100% sure the drug caused my issues, but the timing of symptoms correlates. I applied the 1x a month product to my right leg on November 5th and within 7 days developed twitches in my calf in my right leg, followed by stiffness and weakness in my leg. I applied the 2nd dose in my left leg, and 7 days later developed twitches, weakness, and tightness in my right leg. Reflexes very hyper. Progressively worsened over time. Recently began stretch exercises that have significantly reduced symptoms, especially the tightness. Hopefully, this will pass. I won't be taking any more cholesterol drugs beyond natural remedies, ginger and turmeric. When reading the Amgen study, that was probably biased in favor of the drug since they profit from it, more people died on the drug than the placebo. Incredibly, doctors are prescribing it. The same can be said for statins, as the NIH did a study of millions of people, and the people on statins' life expectancy declined. Healthcare in America is owned by big pharm."

• JoH...
• Taken for 6 months to 1 year
• April 28, 2018

For High Cholesterol "I am an active and youthful 65-year-old woman with a history of high cholesterol (high of 270) since menopause. Tried all the usual drugs, but had severe symptoms of foggy brain. In the interim, I had a cardiac cath, and they found my widow maker already had 30% plaque. Dr. recommended Repatha, which I have been injecting for 9 months. I have started experiencing muscular issues around my knees and feet, which cause pain, weakness, and joint pain. Symptoms are very noticeable the first week after the injection and then decrease somewhat. I am going back to the doctor this week and contemplating going off this drug. This has really affected my mobility - I feel like my legs are that of an 85-year-old. I am curious about my ligaments and tendons after reading some of the previous patient experiences. I am very sad that I was told this drug was without side effects. Patient - beware."

• Tom...
• March 5, 2018

For High Cholesterol "I started taking Repatha in late Nov or early Dec 2016, my LDL dropped dramatically. But after the 2nd week, the pain started. It was excruciating. Shoulders, knees, and hands were intolerable. Couldn't turn on a table lamp. Couldn't hold a toothbrush. I literally and truly thought I was dying. I quit the drug after 3 injections, possibly 4. It took months, if not longer, to recover. Not sure if some problems I have today are not caused by Repatha. I took Repatha because my doc increased my Crestor dose, and I couldn't tolerate it. I convinced my doc to let me now take half a tablet of the lowest available dose of Crestor. I started taking it every other day and am now up to half a tablet daily. It is working, and I have tolerable pain and muscle weakness."

• Jen...
• April 22, 2021

For High Cholesterol, Familial Heterozygous "It has been 6 months since I took one injection of Repatha. I still experience flare-ups of muscle and joint pain, as well as muscle weakness and fatigue. I am a 65-year-old woman of smaller stature. My CRP was over 3 times normal after the one injection, gradually reducing to normal over many months. This medication can cause side effects that last a very long time and greatly affect quality of life. Beware!"

• Not...
• Taken for 1 to 6 months
• January 13, 2022

For High Cholesterol "I have had elevated cholesterol for the past 30 years. I cannot take statins, my doctor put me on Repatha 4 months ago. I feel worse than I have ever felt in my life: severe leg pain and weakness, stomach problems, no energy, feel like my body is slowly deteriorating. I'm 74 years old. Before taking this drug, I worked out at the gym 3 to 4 times a week, had nonstop energy. Now I can't walk 50ft without leg pain and weakness. Repatha needs to be taken off the market: bad medication. Not taking anymore, will take my chances with the high cholesterol (heart attack). I'm praying I can regain my life back."

• MGC...
• Taken for less than 1 month
• November 28, 2021

For High Cholesterol "I wanted to share an experience of a close relative who was diagnosed with necrotizing autoimmune inflammatory myopathy due to this medicine. They were an independent individual about 65 years old who didn’t respond to statins and was given this medicine. She started to experience muscle weakness, ended up 15 times in a hospital for 5 months until she was diagnosed. She ended up with sepsis and respiratory failure, which ended up killing her. Please try diet, exercise, and avoid this medication. I think it’s just being pushed just to make money. References don’t show muscle weakness as a side effect."

• LLL...
• Taken for 1 to 2 years
• August 12, 2018

For High Cholesterol "I started taking Repatha 140 mg every 2 weeks in 2016. My cholesterol was 320. I had been taking other cholesterol drugs, but they did not reduce my numbers. I’m 71, and when I started Repatha, I did not connect my headaches, neck pain, and fatigue to the drug. Around three weeks ago, I started having leg pain, knee pain, leg cramps, and leg weakness. The pain is so bad I can hardly walk. Tomorrow, I see my cardiologist, I will ask if there is something else I can take. The Repatha did bring down the cholesterol back to normal."

• Enr...
• Taken for less than 1 month
• August 13, 2017

For High Cholesterol, Familial Heterozygous "I have taken two 140 mg two weeks apart. I know that I am just starting. For the first four days after each injection, I felt 'tension' and did not feel like being social. Minor body aches, weakness, and fatigue."

• Pet...
• Taken for 1 to 6 months
• September 10, 2021

For High Cholesterol "This so-called miracle drug is a nightmare. I took two injections one month, it had severe weakness, with muscle pain, joint pain, all kinds of other crazy stuff, etc. I stopped taking it because of the high cost and then took another one about three weeks ago. This drug can cripple you and make you feel malice all the time! Needs to be removed from the market…"

• Raz...
• Taken for less than 1 month
• March 10, 2022

For High Cholesterol "Took one injection last Saturday for 5 days. I had a headache, lost 13 lbs, no appetite at all, leg tingling, stuffed-up nose at first, then nose ran like a faucet. Felt weak, no stamina, and my cardio doctor thinks I’m a hypochondriac! Praulent never bothered me for the past 5 years. The insurance company won’t cover Praulent, so I got stuck with this terrible drug! WTH, it’s all about money, not patient care."

• Joh...
• Taken for 2 to 5 years
• July 11, 2022

For High Cholesterol "My cardiologist put me on Repatha after not seeing the improvement in bad cholesterol numbers that he wanted. While not great, my number was always between 100 and 150. I am also on 40 mgs of Crestor daily along with a beta blocker. I began taking Repatha 3 years ago with no side effects that I noticed right away, other than dry mouth. About 8 months ago, I began getting joint pain in my hips and back but didn’t think much about it, just figuring that I am now 60 years old and it’s probably that. The joint pain and muscle weakness have gotten worse, and I’ve seen my doctor about it, and he said I have arthritis in my hips and to stretch in the mornings. That only made matters worse, so I stopped it after a solid week of stretching. I have now come to the conclusion that it must be the Repatha because I have never felt worse physically than I do now, and I am unable to sleep without taking OTC pain medication. My question: how long will it take to feel better now that I have discontinued taking it?"