Repatha and Muscle Pain: What Users Say (Page 2)

• bja...
• Taken for 1 to 6 months
• February 1, 2019

For High Cholesterol "I think this drug is killing me. I have severe pain everywhere, but especially in my back. I am talking severe, with trips to the E.R. Nothing is helping. Now I am beginning to have urinary incontinence and need to walk with a cane. I cannot get up and down alone, and I have to sleep sitting up in a chair with a heating pad since the pain in getting out of bed is excruciating. I am scared to death, and I have only had 2 doses, nearly a month ago now. I took this due to my cholesterol being so high, and my heart history being so bad. I really wanted this to help, but I am really scared now and in pain 24/7. Several people said if you have any history of back, muscle, or bone pain this will intensify it tremendously, and that is what has happened to me."

• Mr ...
• Taken for 1 to 6 months
• June 13, 2016

For High Cholesterol "I have muscle aches with statins. I tried Repatha and did fine for a month or so. It lowered total cholesterol to 120. Then, one day after an injection in my right leg, I got severe right leg cramps. It took two more injections to tie the leg pain to the injections. I thought it might be gout. An orthopedic doctor said it was a torn tendon in the knee. Pain was at a level of 2-8, and I could hardly walk. It settled in the knees. I'm about 10 days since the last injection, and the pain is less every day. I'm definitely sure it's the drug as I have never had knee problems. I hope there is no permanent damage."

• DCv...
• Taken for less than 1 month
• October 3, 2018

For High Cholesterol "After the second dose, I had nausea, missed a day of work for vomiting, no appetite, felt weak. Four days later, I had intractable diarrhea. Called the Repatha nurse line. She read statistics about side effects to me. Asked her for help/advice. She said they don't give advice on dealing with side effects. Within an hour, I collapsed. My mom called 9-1-1. Went by ambulance to the hospital with severe dehydration, which caused acidosis. Spent three days in the intermediate care unit of the hospital. My palms and the soles of my feet itch. I have a hacking cough, head and muscle aches, and blurry vision. The doctors had no answers and treated me for a virus that usually only causes a cold. Read about similar reactions. I asked if it could be from the Repatha; the doctors didn't know what it was or what it was for (at a teaching hospital). Wish I'd done more research. When my doctor prescribed it, I asked if it was safe. He said it was. I believed him, like most patients would their doctors. He was wrong."

• Mai...
• June 29, 2017

For High Cholesterol "Horrible experience. Lost all lower body strength. Severe, and I mean severe, knee pain. My knees would burn all over, and just a light touch to them would make the pain even worse! I have had bad tendinitis for 4 months and pulled back muscles. Walking became difficult. It didn’t even bring my numbers down. I stopped taking it and felt my strength and muscles return. Still waiting on my tendinitis, but I feel it is finally getting better. Not safe, not effective, wouldn’t recommend to a lab rat."

• mik...
• Taken for 6 months to 1 year
• February 6, 2025

For Cardiovascular Risk Reduction "Not sure about all the bad reviews, this is a wonder drug for me. I have none of these side effects: muscle aches, back pains, etc. Taken twice a month for the last 8 months, lowered my LDL to 25 in a matter of months. (60-year-old male with a high calcium score)."

• Net...
• Taken for 1 to 2 years
• October 22, 2019

For High Cholesterol "After taking Repatha for a year and a half, my cholesterol was lowered dramatically. But I had sinus infections that got worse, respiratory infections, and was diagnosed with COPD 1 year ago after taking Repatha faithfully. I have always had sinus problems and seasonal asthma, and bronchitis, maybe once a year I had to use an inhaler. Since being on Repatha, I have had asthma attacks and pneumonia so bad I had to be hospitalized. Exactly 4 times in a year. I never smoked, and now I am on 3 inhalers and a nebulizer. I have always had a pneumonia shot every 5 years and never got pneumonia for over 15 years. I am fatigued and have muscle pain. I decided to stop Repatha on my own and see what happens."

• Cga...
• May 16, 2021

For High Cholesterol "I started Repatha because statins were causing heartburn, muscle aches, and dry mouth. After the first dose, I was OK, but after the second dose, I had a nosebleed that soaked several paper towels and lasted about 15 minutes. I googled to find out if that is normal and found that nosebleeds are common in women over 60, which I am. I also had constant nose dripping like water and fatigue so bad that I could hardly make it to my mailbox. Some shortness of breath as well. After several unexpected nosebleeds at very inopportune times, I stopped it."

• THB...
• Taken for 1 to 6 months
• March 14, 2023

For Cardiovascular Risk Reduction "I had a slight heart attack in September 2022. I was put on 140 mg/ml of Repatha by October. Cholesterol went down significantly. I reported muscle pain in both upper arms. The cardiologist said it wasn't Repatha. I am not able to take Lipitor or Crestor, as I have severe thigh pain with statins. I have been on Repatha for 5 months. Shoulder and arm pain have gotten worse, and now I have pain in my hand and lower arm, pins and needles in my arm as well. I am not taking the next dose."

• Ral...
• Taken for 2 to 5 years
• April 27, 2023

For Cardiovascular Risk Reduction "I’m an inherent atherosclerosis patient, age 74. I have walked at least a half hour every day since 1997. I underwent quadruple bypass surgery 25 years ago and have been on statins until 4 years ago when my cardiologist prescribed Repatha to lower my LDL cholesterol. This product works great in lowering cholesterol and reducing my LDL under 60. However, I trusted my doctor, who I do not blame for the BAD side effects, as it came with the Big Pharma label as “having no side effects,” and as a new wonder drug with great results, it seemed like a godsend. Please be warned: the toxic effects tend to creep up on most people. I developed low energy levels, muscle aches, joint pain in my hip and feet, and recently severe low back pain with resultant loss of sleep. I also wake at times with severe pain in my hand joints for seemingly no reason. I recently stopped taking this drug on my own and plan on returning to a statin regimen treatment if my cardiologist agrees, but I’m through with this."

• Ter...
• Taken for 1 to 6 months
• May 7, 2021

For High Cholesterol, Familial Heterozygous "I began taking twice-monthly Repatha in November 2020 on the advice of my cardiologist. I am a healthy and active 68-year-old female with familial hypercholesterolemia. Previously, I had tried four different statins and various doses, all of which resulted in considerable muscle pain and night cramps. Things seemed fine until my third Repatha injection when I began having severe pain in my right arm and shoulder. I didn't link the pain to this, so I continued taking my injections, eight altogether, until my final dose at the end of February. By then, I was experiencing increasingly severe pain in both shoulders and arms, weak leg muscles making it difficult to stand, dizziness, and fatigue. Although Repatha dropped my LDL from 177 to 68, the side effects are debilitating. I am done with Repatha and statins. I stopped taking Repatha in late February, but two months later, the side effects continue to wax and wane. I am praying my system can recover and my life return to normal."

• Ste...
• Taken for 1 to 6 months
• October 21, 2017

For High Cholesterol "I am 69 years old. I have been an athlete all my life and have run over forty thousand miles. I do not tolerate statins due to severe muscle pain. I was walking 6 miles a day prior to taking Repatha. After three shots of Repatha, I developed debilitating pain and weakness in my back and right leg. 9 on the pain scale. I still, three weeks later, have difficulty walking. It seems to be improving somewhat, with better days followed by a more difficult day. This has had a terrible impact on my quality of life. DO NOT TAKE this drug!"

• Vic...
• October 8, 2018

For Cardiovascular Risk Reduction "I can't take statins. My doctor prescribed Repatha to me and confirmed to me that it has no side effects. I took 3 injections. I started feeling muscle pain and back pain. I felt very weak and fatigued. I checked with my doctor and pharmacist. They said that Repatha is causing these problems. I wish I never took Repatha. I wish someone could tell me how long I have to wait to feel better and get back to normal conditions. It has been 2 weeks since I took my 3rd injection. I recommend that you don't take this drug. It's dangerous. I don't know what to do now."

• Ste...
• Taken for 1 to 6 months
• December 11, 2017

For High Cholesterol "After severe muscle and joint pain following my third injection, I discontinued use of Repatha at the end of Sept. 2017. It is now the middle of December 2017, and although the pain has subsided somewhat, the use of my right leg has been severely compromised. I feel the sensation of an electric shock 24/7 that moves around my right leg. I have repeatedly contacted Amgen for info. Specifically, I asked whether symptoms would subside or whether I would have this permanently. They repeatedly said, 'call your doctor.' Well, the doctors don't know because this is a relatively new medication. Repatha has refused to answer any of my questions directly and has provided NO support. It seems they really don't want to know about this. BE CAREFUL!!"

• So ...
• December 3, 2019

For High Cholesterol "I started Repatha 1 month ago. This medicine has made me so sick, I can’t hardly function. Nausea, bad diarrhea, muscle aches, flu-like symptoms, overall, just fatigued. Please don’t take this medicine, it is terrible. I stopped taking it 1 week ago, and it’s still making me so sick."

• Anonymous
• Taken for 1 to 6 months
• October 20, 2019

For Cardiovascular Risk Reduction "I have been taking Repatha for 3 and 1/2 months. At first, I was fine, my cholesterol went down, and by the third month, I was getting blurred vision, headaches, severe fatigue, burning in the feet, and muscle pain in the back of my neck. It's gotten to the point where I can't even work. I'm so, so tired, short of breath, wheezing, and urinating a lot. Although my cholesterol went down, it's not worth taking Repatha if there's no quality of life for me."

• AMS...
• Taken for less than 1 month
• September 10, 2019

For Cardiovascular Risk Reduction "One injection, and I am not going to take it again. First chills, then horrible muscle pain in upper chest and neck. Gained 6 lbs in two weeks. Put me on edge. Still suffering. Woke up in the middle of the night with more pains. Only a painkiller helped. I do not believe in the LDL theory anyway."

• Fri...
• Taken for 2 to 5 years
• December 17, 2020

For High Cholesterol "I was prescribed Repatha after trying and not being able to tolerate a multitude of different statins, which left me fatigued and with muscle pain. I have been on Repatha for over 3 years and, knock on wood, have not had any issues with it. It has been a great drug. I was surprised to read all the negative reports here and wondering if it is a self-selecting sample and fails to represent a balanced picture of this medication."

• Sso...
• Taken for less than 1 month
• July 24, 2018

For High Cholesterol "Worst drug on the market. If I could give it a zero, I would! After 2 injections, I experienced extreme muscle weakness and joint pain. I discontinued the medication. Contacted the FDA, they informed me I was not the only person they had heard this from. I asked how long before the side effects were gone? This was March. They told me the end of May! It did get better. But recently, the muscle pain is back. It also grossly elevated my cholesterol after I discontinued the medication. I would not recommend anyone take this medication. The pros vs. the cons are just not worth it. I don't think they can give a 125 lb woman the same dose they give a 300 lb man and not expect side effects."

• Mik...
• Taken for less than 1 month
• March 24, 2019

For High Cholesterol "After one injection, back and muscle pain was terrible! Also, I told my doctor that my last labs were high because I hadn't fasted. I got labs from fasting back after I took my first injection. I should have waited to take that shot, but the doctor convinced me I needed it. Levels of cholesterol labs were 212 total, 160 LDL, 38 HDL! Didn't even need this poison in the first place! Now counting down the days until it's out of my system."

• Ref...
• Taken for 1 to 6 months
• October 31, 2019

For High Cholesterol "Using Repatha for approx 6 months because me, statins, and my kidneys weren't friends. Pain in my shins (feels like shin splints), excruciating hip pain especially when sleeping (I'm a side sleeper). Pain in thighs as well, hard to walk and get up from sitting. Always feel sore, like I've been beaten up. Back pain, not just lower back but all over. Shoulder and neck pain, could barely turn head far enough to check oncoming traffic when making a right turn. Night sweats. Heart palpitations in the middle of the night. Increased bathroom trips at night. Intermittent diarrhea. It just kept getting worse. As I read the reviews, I have to believe this has been brought on by the bi-weekly injections. Testing for Lyme disease to rule that out. Repatha was great for my numbers, but it's much too painful to continue."

• Way...
• Taken for 1 to 6 months
• March 26, 2019

For High Cholesterol "WARNING: Repatha comes with very serious side effects. 1) SEVERE FLU... cough, sore throat, congestion, massive mucus, headache, etc. 2) EXCRUCIATING BACK PAIN... could not walk for two weeks, able to walk now, but back pain continues three months after the last injection. 3) DIGESTIVE PROBLEMS... heartburn. 4) CONFUSION... difficulty concentrating. 5) INTERNAL SHIVERING... but not cold or external shivering. 6) WEAK... due to muscle and joint pain. All side effects have improved since discontinuing use three months ago. Back pain, internal shivering, and some muscle/joint pain continue after three months."

• Cyn...
• September 21, 2019

For High Cholesterol, Familial Heterozygous "The worst experience. Don’t take it. Am going to report to FDA. Bad drug, can’t use left leg, gives out on me, severe muscle pain all over, pelvic pain where leg joins body, affected area back and severe nerve pain, tremendous pain over the last 3 months, causes tremendous issues with muscles. Apparently, a lot of trials not reliable. Is appalling! Don’t know if I will ever get better. So debilitating."

• Anonymous
• Taken for 1 to 6 months
• July 27, 2022

For High Cholesterol, Familial Heterozygous "I have taken 7 injections of Repatha. I started with the 2-week injections, which caused side effects of leg, ankle, shoulder pain, and also a runny nose. I decreased the injection to once a month. I have muscle pain, and now severe diarrhea, nausea, which started within 12 hours of injection. I'm weak, and my legs hurt. I will never take this poison again. I hope I get through this."

• mep...
• Taken for less than 1 month
• June 3, 2019

For High Cholesterol "Just started on Repatha and want to share an approach. Due to concerns over potential side effects (reading here + own experience with statins), I withdrew the Sureclick injector before it was fully emptied. Watched several YouTube injections and found it was about 6 seconds to fully auto-inject. Sat in my bathtub, withdrew the injector after 2 seconds. The rest of the medicine kept ejecting from the Sureclick injector and went into the tub. I estimate 1/3 of Repatha went in my body. The next day, I started to experience fatigue. Today, muscle pain in shoulders, back, and back of legs. I am sure I will be criticized here for wasting $. But after reading how severe some of these side effects are, I am completely at peace with my approach. Sharing in case others might think about."

• Dee...
• Taken for less than 1 month
• March 12, 2020

For High Cholesterol "I just started taking Repatha for 2 weeks now along with Zetia. I've had no side effects so far. I've read the other reviews, and it's scary. I was on Crestor, and my muscles ache so bad. My stomach was always hurting, and I was feeling like I wanted to vomit. Hopefully, it will lower my cholesterol."