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Repatha and Fatigue: What Users Say (Page 4)

Reviews for Repatha

Commonly mentioned side effects
  • Rai...
  • April 18, 2022

For High Cholesterol "Been on all the statins. My body is unable to tolerate them. The worst being Lipitor. It is a horror drug and was a current affair program in Australia some years ago. Unfortunately, my diet has a limited impact. Triple bypass and three stents further down the track, I felt doomed. Then my new cardiologist suggested this Repatha. Great! And it worked wonders for me, and there appeared to be no side effects other than a nose drip when I did physical stuff. Been on it for approximately three or so years, and it helped keep my cholesterol in check. But in the last six or so months, I have been feeling more fatigue, plagued with lightheadedness, a rubbery weak sensation in my legs, arms at times feeling weakish, along with a head fog. I now suspect it being Repatha. Been on a plant-based diet and now just try that on its own."

10 / 10
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  • RSa...
  • Taken for 6 months to 1 year
  • February 13, 2021

For High Cholesterol "I am a 60-year-old male. Very fit and active. Family history of very high cholesterol led me to a triple bypass last year. Tried statins (all of them) for years with little reduction in my cholesterol. On Repatha now for almost a year. Worked beautifully to lower my cholesterol to almost nothing. Have some minor side effects I attribute to this medication (neck muscle tension pain, fatigue). But without it, my bypass plumbing would soon clog, and I would be a dead man. Of course, I will keep taking it. By the way, if it isn't obvious, this forum isn't scientific. Nobody should make a decision about whether to take this (or any) medication based on what they read here. The reason is, most respondents are here precisely because of their side effects. Thus, feedback from folks like me, who have had a generally positive experience, is fewer. Listen to your doctor."

9 / 10
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  • Ala...
  • Taken for 6 months to 1 year
  • February 5, 2021

For High Cholesterol "I just read some of these comments and cannot relate to them. I started on Repatha and my LDL went from high 90s to 24, and I was very happy. Other than old age pains and pains from statins, which I have been working with my doctor to reduce, it might be causing, it seems I am taking something different from what I have read in these comments. It does what was expected. It lowered my LDL and cholesterol. I am monitoring my fatigue, but I believe it is work-related and caused by my gym being closed for one year now. I have read scientific articles on the drug and have not come across these other comments. Age mid-70s."

10 / 10
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Frequently asked questions

  • Jil...
  • Taken for 1 to 2 years
  • April 23, 2025

For High Cholesterol "Repatha lowered my cholesterol and kept it down. Side effects were bladder pain, multiple UTIs, and extreme fatigue."

6 / 10
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  • dog...
  • Taken for 1 to 6 months
  • January 11, 2016

For High Cholesterol, Familial Homozygous "Fatigue, headaches, muscle aches."

6 / 10
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69 Report

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  • DJW...
  • Taken for 1 to 6 months
  • March 12, 2025

For High Cholesterol "While this drug does what it is supposed to do, lower cholesterol, the side effects were unbearable. Back pain, shortness of breath, headache, muscle pain, severe fatigue."

3 / 10
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  • Car...
  • Taken for 1 to 6 months
  • June 20, 2019

For High Cholesterol "Three months on this drug and I lost all my energy and got chronic diarrhea. One year later and I still have the side effects. It has not been proven that this drug saves lives. BEWARE."

1 / 10
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34 Report

More FAQ

  • Nei...
  • Taken for 1 to 6 months
  • January 16, 2019

For High Cholesterol, Familial Heterozygous "POISON. Flu syndrome immediately after one injection, followed by 8 months of muscle pain, cramps, and tightness, mostly in legs. Fatigue as well. No help from baclofen, diazepam, OTC pain meds."

1 / 10
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  • Lad...
  • Taken for 1 to 6 months
  • June 18, 2018

For High Cholesterol, Familial Heterozygous "Only took 12 doses and couldn’t move. Extreme fatigue and lethargy, back pain, and horrible leg cramps. Doctor has stopped for now."

4 / 10
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  • Rob...
  • Taken for 1 to 6 months
  • August 26, 2024

For Cardiovascular Risk Reduction "I am sleepy and fatigue easily. Could Repatha be a cause?"

10 / 10
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  • Mrs...
  • Taken for less than 1 month
  • May 8, 2023

For High Cholesterol, Familial Homozygous "I just had my first dose, 140 mg. I woke the next morning with a very swollen face and edema of my lower extremities and unusual fatigue. It’s the weekend. I will call my cardiologist on Monday."

2 / 10
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  • Way...
  • Taken for 1 to 2 years
  • April 19, 2023

For High Cholesterol "Random aching in shoulders and knees, blurred vision, low energy, lethargic."

3 / 10
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  • Ken...
  • Taken for less than 1 month
  • July 26, 2022

For High Cholesterol "After one week, fatigue, personality change, and loss of sex drive/libido! After the first week! Not sure if I will continue."

6 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.