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Repatha and Back Pain: What Users Say (Page 4)

Reviews for Repatha

Commonly mentioned side effects
  • Anonymous
  • Taken for 6 months to 1 year
  • January 16, 2022

For High Cholesterol "This medication is horrible. I started it for the second time and feel terrible. I am going to try contacting 60 Min. It should be taken off the market. Having shoulder pain, back pain, weekends, can't sleep, you name it."

1 / 10
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  • Mau...
  • Taken for 6 months to 1 year
  • October 26, 2018

For Cardiovascular Risk Reduction "Have had great results but have a continuing problem with sneezing and a runny nose, also back pain and dizziness. Went to the allergist and checked nothing wrong there. Problem always gets worse after the shot."

6 / 10
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16 Report
  • JAD...
  • Taken for 1 to 2 years
  • March 28, 2022

For High Cholesterol "I have to say I'm truly surprised at all the negative reviews. I took Repatha twice a month for a year and a half and never had a single side effect. The statins, and we tried five or six of them, made me miserable. Some caused back pain, some caused muscle pain, and others caused sexual side effects. Once on the Repatha, I felt fine, and my blood test results were ones my doctor said he would pin to his refrigerator, they were that good. I would have continued taking it, but my health insurance got canceled. Repatha does such a good job of reversing plaque buildup that before you quit taking it, I would seriously investigate other reasons for the supposed side effects. Statins are much more likely to cause side effects, and everyone I've talked to that takes Repatha has not had any of the side effects people here are talking about. Personally, I think it's a lifesaver."

10 / 10
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Frequently asked questions

  • Her...
  • Taken for 6 months to 1 year
  • July 29, 2019

For High Cholesterol "I have had high cholesterol my entire life. Four bypasses and numerous stents. I had little to lose as I could not tolerate the statins. Been on Repatha nine months. I experienced back pain and arthritic symptoms. I am now on CBD oil 1000 mg, and it helps tolerate the side effects. My LDL went from 110 to 10. Now I am afraid it is too low. I know the CBD helps because I ran out and was bedridden for two weeks. Back pain was terrible and arthritic all over. Got the CBD and was better in two days. It worked for me."

9 / 10
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  • Kat...
  • Taken for less than 1 month
  • November 9, 2021

For High Cholesterol "I took Repatha Pushtronex on Feb. 15, 2021. I had to go to the ER, with leg swelling, itching face, had an X-ray of lungs, coughing, couldn't breathe or swallow, my face was bright red, headache, and high BP. In the following days, I could not urinate, had back pain, hard bladder, went to urologist, and urine was clear, put on cranberry, probiotics, prebiotics. Saw gynecologist because of pain in belly and ordered a sonogram, but it was still bladder/back pain. My face broke out, DRAINING visits to the dermatologist went through 4 tubes of hydrocortisone valerate, no relief. Went to GP, she sent me back to the dermatologist and on clindamycin face gel and pills for my face as it looks to be bad acne. Never had my face look like this. On Benadryl, itching, burning since Feb. and it's Nov. 9th! I am suffering. Cardiologist has no answer. Repatha 800# says, 'We don't know when it will get out of your system, it lingers.' 9 months? POISON."

1 / 10
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  • Tho...
  • Taken for 1 to 2 years
  • May 20, 2023

For High Cholesterol "I have been on it for a year and a half, and it’s been very effective in lowering my cholesterol. However, recently I started experiencing terrible lower back pains. I got an MRI of my lumbar, which shows that I have some bulging. Perhaps the medication is exacerbating my condition?! The only way for me to know is to stop taking it. Is anyone out there with similar conditions who stopped taking it? If so, please tell me if your back pain has gone away, and if so, how long did it take? Thank you."

6 / 10
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  • Pap...
  • August 22, 2021

For High Cholesterol, Familial Heterozygous "I am a 66-year-old male with familial high cholesterol and triglycerides. I have been unable to take statins and other meds for lowering cholesterol due to elevation of muscle enzymes, which causes muscle pain and weakness. After a stent, the doctor wanted me to take Repatha. I took it for 5 months, and due to other health issues, I did not realize I was having issues until a heart catheterization came back normal. I had chest pressure, shortness of breath with minor exertion, sweating very easily, body aches, fatigue, back pain, and muscle aches all over. My muscle enzymes test, which I had to request, was very elevated. I immediately stopped Repatha. Chest discomfort stopped immediately, breathing is better, and sweating stopped, but I am still having severe back and muscle aches in my legs, with my legs feeling very rubbery. My advice is to pay very close attention to muscle aches if you take this medication and have problems with other cholesterol medications."

1 / 10
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More FAQ

  • Ren...
  • Taken for 1 to 2 years
  • August 18, 2022

For High Cholesterol, Familial Heterozygous "Numbers are great, but severe side effects! Such strong hay fever-type effects with eyes and nose running, sneezes so strong they hurt, and itching all over, but especially head and eyes. If I take Claritin or similar, I have bad insomnia. Left hip and knee pain. Lower back pain when walking and weight gain. I am stopping the Repatha injections - quality of life down."

5 / 10
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  • Chr...
  • Taken for less than 1 month
  • June 12, 2023

For High Cholesterol "From the first day, I experienced itching, took an antihistamine, and that helped, had lower back pain and neck pain, generally felt unwell, and fatigued daily. I am not sure if I want to do this again in a week and a half."

5 / 10
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  • Mol...
  • Taken for 1 to 6 months
  • August 16, 2021

For High Cholesterol "I have not tolerated statins well due to side effects. A doctor recommended Repatha injection, which I was not excited about as I do not like needles, but decided to give it a try and to overcome my fear in lieu of better cholesterol health. I took my first dose on 8/10 and was feeling fine. On 8/12, I noticed a slight discomfort in my hip area and thought I had slept wrong… Woke up 8/13 and had severe pain in my hip, stomach, and back and could barely get out of bed. Tylenol had no effect. I thought about going to the ER but decided to tough it out until Monday because I had a previously scheduled appointment. I also experienced higher blood pressure, tiredness, and I believe my glucose level dropped. I have already sent the doctor a message that I will not be taking the second dose. I am waiting to see what the doctor says. In the meantime, I am still unable to move or sit without pain, and while it may be effective, the side effects are not worth it."

1 / 10
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  • Zar...
  • September 13, 2021

For High Cholesterol "I started having body aches with severe headaches, coughing, and chills, back pain. My blood pressure went high, been weak all day, and I'm going through the second day, not sure how long this will last, but I hope you don't delete my comments."

1 / 10
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  • Bib...
  • Taken for 1 to 6 months
  • September 22, 2021

For High Cholesterol "Been on Repatha for 5 months. My cholesterol has come down quite a bit. But, I’ve gone from playing PB, low-impact aerobics, yoga, and walking several times a week to gaining 10 lbs, joints hurting more than ever, back pain, and sciatic nerve pain the worst I’ve ever had, and I’m very lethargic now. Not happy with what’s happening to my body, even though I had some health issues. I shouldn’t have gone from all of this activity in such a short time to using a cane some days, being put on prednisone for a week, taking pregabalin and Tylenol every day, and now steroid injections again. I was doing pretty well with my pain management until I started Repatha. Now I’m getting ready to return to the pain management clinic after 3 years. I’m very sad about this. I will be discussing this with my cardiologist as soon as I can get an appointment. Is Repatha the culprit that’s causing my return to severe pain and weight gain? I don’t know."

8 / 10
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  • BEa...
  • Taken for 1 to 6 months
  • April 27, 2018

For High Cholesterol, Familial Heterozygous "Have been taking Repatha for two months, with an injection every two weeks. Almost immediately began to feel the malaise, sinus pressure, dry eyes, and leg weakness. After the last two injections, began to have severe low back pain, pain in both hips, and increasing numbness in both feet. Blood pressure has also increased slightly. Doctor states that it is not caused by Repatha, however, when treated by the general practitioner for the symptoms above, they have been unable to identify the proximal cause."

6 / 10
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  • Dru...
  • Taken for 1 to 2 years
  • July 3, 2025

For Cardiovascular Risk Reduction "Rash in the temple area around the right ear, small causes stomach to flem up with certain oils, foods have to vomit clear flem out to allow the swallowing of evening food (not every day), positive effects good blood tests, better circulation, better eyesight the swallowing problem can be bad, if the cost gets stupid I'm out, back pain is much lower than other drugs, statins."

6 / 10
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  • Tat...
  • Taken for 6 months to 1 year
  • June 25, 2025

For High Cholesterol "I took 17 doses of Repatha on the 2-week (140 MG/ML) schedule of self-injections. LDL level improved to almost normal on the first check and a bit higher on the second. During this time, I had varying reactions to the shots, ranging from euphoria on the first shot to extreme, long-lasting back pain (right side above waist) that caused me to stop Repatha. Some side effects were clearly from the shot, new problems, and directly linked in time to the shot. Other side effects were more like a return of old problems or exacerbating of symptoms. I found that doctors believed the side effects listed by Amgen but not the ones that were unclear as to what caused them. Now that I am in detox from Repatha, symptoms are less but not gone. So my advice is to believe your own eyes. If you think Repatha caused something, believe yourself, not the Amgen lists of side effects. Repatha should be fully out of my system on July 21, 2025. I hope to be rid of these symptoms by then, and that is when I will know."

8 / 10
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  • Tex...
  • Taken for less than 1 month
  • April 3, 2025

For High Cholesterol "First dose today, and I feel absolutely horrible! Like the flu, my joints, back, neck, shoulders, everything hurts! I couldn’t tolerate statins for this reason here! Hope it goes away!"

7 / 10
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  • DJW...
  • Taken for 1 to 6 months
  • March 12, 2025

For High Cholesterol "While this drug does what it is supposed to do, lower cholesterol, the side effects were unbearable. Back pain, shortness of breath, headache, muscle pain, severe fatigue."

3 / 10
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6 Report
  • Tob...
  • Taken for 6 months to 1 year
  • August 19, 2020

For High Cholesterol "My wife took Repatha, lowered her cholesterol by half. But now, after 6 months, has lower backache for the last 2 months, and she gets occasional blurry vision."

10 / 10
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31 Report
  • Ray...
  • Taken for less than 1 month
  • April 11, 2017

For High Cholesterol, Familial Heterozygous "After taking the 2nd shot, I started having back pain, pain in my knees and hands. I can't take statins for the same reasons. I was hoping this was the drug without the pain."

2 / 10
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40 Report
  • ray...
  • April 9, 2023

For High Cholesterol "Tried a 140 mg injection the first time. I felt very sick that night, with foul gas and nausea, and now left with back and leg pain and a constant headache."

1 / 10
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  • Lad...
  • Taken for 1 to 6 months
  • June 18, 2018

For High Cholesterol, Familial Heterozygous "Only took 12 doses and couldn’t move. Extreme fatigue and lethargy, back pain, and horrible leg cramps. Doctor has stopped for now."

4 / 10
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  • Okt...
  • August 27, 2017

For High Cholesterol, Familial Heterozygous "Took my 3rd fortnightly shot, and I will not take any more. The side effects are getting worse: back ache, muscle ache, runny nose, feel like I'm run down with a cold."

2 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • March 21, 2024

For High Cholesterol "Having lots of the side effects: dry mouth, runny nose, sore throat like a cold, ears, dizzy, leg pain, fainting. Diarrhea, headache, backache."

2 / 10
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6 Report
  • Ano...
  • Taken for 1 to 6 months
  • May 31, 2025

For High Cholesterol "I have experienced back pain. I'm really tired today and have brain fog. Doctor just changed the dose to a higher one. My hair has been falling out by handfuls since I started Repatha."

10 / 10
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  • ray...
  • April 22, 2023

For High Cholesterol "Repatha lowered my cholesterol by 100 points within a week. However, I have back pain, UTI, high A1C, blurred vision, insomnia, sore throat, and weakness (can barely walk 3 blocks). Not worth it."

2 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.