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Tri-Sprintec and Sexual Dysfunction: What Users Say

Sexual dysfunction: mentioned by 68 users (8.1%)

Based on user experiences from 841 Tri-Sprintec reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

acne 24.4%
nausea 24.0%
mood swings 23.9%
weight gain 19.0%
depression 16.3%
cramps 12.6%
headaches 11.4%
anxiety 11.2%
sore breasts 8.3%
sexual dysfunction 8.1%

Reviews for Tri-Sprintec

Commonly mentioned side effects
  • Anonymous
  • December 17, 2009

For Birth Control "Within the 1st week I went from a happy, optimistic girl, to a very unhappy, unstable individual. My experience: crying for no reason, complete misery, severe weight gain, antisocial, exhausted, nauseous, dry eyes, high anxiety, NO sex drive, painful sex, cramping, bloating, irrational behavior."

1 / 10
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140 Report
  • Anonymous
  • December 17, 2009

For Birth Control "Within the 1st week I went from a happy, optimistic girl, to a very unhappy, unstable individual. My experience: crying for no reason, complete misery, severe weight gain, antisocial, exhausted, nauseous, dry eyes, high anxiety, NO sex drive, painful sex, cramping, bloating, irrational behavior."

1 / 10
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140 Report
  • Kai...
  • Taken for 1 to 6 months
  • February 10, 2020

For Birth Control "This birth control for me has only really done me a few favors, and that’s being free and not getting me pregnant. However, that being said, the side effects I can’t justify. I recently turned 18 and started taking the pill. My first month was fine, but the more I take it, the worse I’m getting. I’m having constant anxiety and panic attacks. I always feel extremely worried, stressed, and overwhelmed. I’m very irritable and impatient, not to mention it gives me horrendous headaches and recently extreme nausea and vomiting. Not to get into too much detail, but just absolutely projectile vomiting everywhere. Feeling very feverish, hot, and cold sweats, not to mention for period cramps, it does nothing. My cramps feel just as bad as they were before, and my period is just as heavy and maybe even a little longer. My sex drive has definitely decreased, and sex is painful, I nearly bleed a little each time. It’s causing me to go crazy, and I have trouble even sleeping with some of the symptoms."

2 / 10
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32 Report
  • kyg...
  • Taken for 1 to 2 years
  • September 1, 2019

For Birth Control "My experience with Tri-Sprintec has been wonderful! I've been on it for over a year now and have never had any major complications. I switched to Tri-Sprintec from Trinessa due to my insurance, but needless to say, they both worked well for me. I lost nearly 30 pounds, and it decreased my appetite, my skin is finally clear, with occasional breakouts when my period is about to start. As far as sex goes, with me being on the pill, my boyfriend and I don't use protection, and it's kept me baby-free! The only thing negative I have to say is when my body was adjusting to it after I just got it, I was so moody and depressed, and my libido (sex drive) was low for the first month or so. Overall rating for me is 10/10! But keep in mind, everyone's body is different, so your experience may be different!"

10 / 10
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30 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • March 16, 2014

For Birth Control "I started this pill a little less than a year ago, about six months after becoming sexually active. I have never had any problems with this pill. I was on Accutane for almost a year, and even it didn't clear my face up as much as Tri-Sprintec has. It has also made my periods perfect, they last 5-6 days and are super light. My weight has not changed at all. I have noticed my sex drive has gone down, but it works great for a contraceptive. I stopped using protection (condoms) about 4 months ago and am still baby-free! This pill is wonderful, and I highly recommend it to anyone looking for a cheap and effective contraceptive or acne fix."

10 / 10
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29 Report

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  • Anonymous
  • Taken for 2 to 5 years
  • September 17, 2019

For Birth Control "The first year of being on Tri-Sprintec, I did great. The second year has been rough. Bad anxiety, depression, and I'm just so freaking tired all the time, some days it takes everything I can do to just make it through an 8-hour shift and make it back to my bed. I've always been a very energetic person until this past year. I also haven't had a sex drive in forever, it seems like. And these mood swings, I can't even deal with. I've really been struggling the past year. Never really thought that it was the birth control doing all these crazy things to me."

3 / 10
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12 Report
  • Ano...
  • Taken for 1 to 6 months
  • February 28, 2020

For Birth Control "I’ve been on Tri-Sprintec for about 5 months now, for bad cramping. I’d like to say that I am a lesbian, so this is not a contraceptive for me, it was just to alleviate my period pain and heavy bleeding. The first three months were the worst. I gained a little weight, was the most moody I’ve ever been, and was sad often. However, once you get past all of that in those 3 months, it's a lifesaver. My period pain has decreased so much that honestly I’ll forget I’m on my period, it’s made them lighter and shorter. My skin is clearer, the weight I lost from the first 3 months is gone, and I’m not moody anymore. However, it does kill my sex drive almost completely, so if you are worried about that, take it into consideration before trying this birth control."

8 / 10
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  • Coo...
  • March 13, 2019

For Birth Control "Increased depression and headaches all the time. Got rashes around my face and broke out really bad. Anxiety and mood swings off the roof. Still have cramps and gained so much weight. No sex drive whatsoever and feel nausea all the time."

1 / 10
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12 Report
  • Dis...
  • Taken for 1 to 2 years
  • February 1, 2020

For Birth Control "I had been on Tri-Sprintec for about a year and a half to prevent pregnancy. A few months after starting to take it, I began to gain weight and became severely depressed. I would cry at every little thing, and my period cramps were worse than they were before. I couldn't sleep and had no sex drive. It didn't even occur to me that these changes were due to my birth control until I finally went to the doctor, who told me that sounds like symptoms of Tri-Sprintec. I just got an IUD placed, and I have never felt better, I have my personality back."

1 / 10
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10 Report
  • Tay...
  • Taken for 2 to 5 years
  • September 3, 2020

For Birth Control "I love this brand of birth control! I started taking this brand about 3 1/2 years ago, and it’s helped so much. During that time, I did switch to a different brand to try something else, and it was the worst decision, so I switched right back. My periods are so light and short, which is a plus. It helped clear my skin up right away, but recently it’s been a little worse (I blame that on stress). Only major complaint about the pill is a lack of sex drive. Highly recommend this for birth control."

10 / 10
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8 Report
  • Cat...
  • Taken for 1 to 2 years
  • April 22, 2015

For Acne "I started Tri-Sprintec in November 2013. The first month, I was extremely moody and had anger problems. After three months, my acne cleared up. It's been over a year, and I haven't seen a spot since! This is great; I also am very active. Some days, my sex drive is not there; usually, this happens the first week of the pack. So, for birth control purposes, I would rate this as a 10 as well. I've never had any problems and never had any pregnancy scares. My boyfriend noticed that I went up a cup in size. I didn't gain any weight really; I'm just 98 lbs, and the maximum I would be 100 lbs. I would recommend it to anyone who has acne problems. But wait 3-4 months for results."

10 / 10
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17 Report
  • Sha...
  • Taken for 1 to 2 years
  • October 3, 2020

For Birth Control "Tri-Sprintec was the first birth control I ever took. I was 17 years old, and I took it until I was 19. Tri-Sprintec caused me the worst years of my life. I was so depressed to the point where I could barely get out of bed sometimes. I got to a point where life was too much. I cried almost every day for the last 2 months on this pill until I couldn’t take it anymore! I went to the doctor, and she told me, surprisingly, that everything I was feeling was common taking Tri-Sprintec! She immediately switched me over to “Sprintec,” and I have not been having issues with my hormones at all. The only thing I hate about this pill is that it takes away my sex drive. I literally never get “in the mood” anymore, and it sucks. I don’t even remember the last time I was horny... but I guess you have to give to receive."

2 / 10
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7 Report
  • MM2...
  • January 7, 2014

For Birth Control "My doctor recommended this to me since I was on Ortho Tri-Cyclen Lo before, and after having a child, it no longer worked as well for me and began to cause cystic acne on my chin. She said Tri-Sprintec is the generic for Ortho Tri-Cyclen Lo and works similarly to your natural body's hormone process. Since I started it, each month my skin has gotten clearer, and the PMS mood swings before my period are getting better. I was definitely more moody after I started taking this birth control. The biggest thing I've noticed is a lack of sexual drive, but my skin's clear, little weight gain, and no hair loss. So I'm sticking with it."

10 / 10
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14 Report
  • Not...
  • November 23, 2014

For Birth Control "I was on this BC for two and a half months before I decided to stop. This was not my first BC, and previously I had no issues with BC. The first month was okay, but around the second month, I started having terrible nausea at nighttime. To the point where I wasn't able to leave the house. I also had an extremely decreased libido. Went from having sex daily to maybe once a week. No change in weight or appetite other than not wanting to eat because of the nausea. I have now been off of Tri-Sprintec for about a week and haven't had any nighttime nausea at all. Every BC affects everyone differently, but this was not the one for me."

4 / 10
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16 Report
  • Hel...
  • Taken for 1 to 6 months
  • February 9, 2019

For Birth Control "I am quitting this birth control immediately. I took Tri-Lo-Marzia for a month before I was switched to this for insurance. Both pills diminished my sex drive to where I almost never want it. Which is insane because before the pill I would want sex 4-5 times a week. Strangely enough, it has also made it incredibly difficult for me to get wet or orgasm... which I can't believe is even a thing. I've probably orgasmed once since taking it. After taking this pill, my face broke out so bad. I'm getting pimples in places I never thought I could. I just woke up with a pimple by my ear. This pill has made me very emotional. I have probably cried 10 times this month for the most stupid reasons. This pill has me fed up with birth control. It's not worth taking birth control if it's going to absolutely kill my sex drive and screw with my head and relationship. My review honestly sounds exaggerated, but this pill literally did all of those things to me."

2 / 10
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8 Report
  • Hel...
  • Taken for 1 to 6 months
  • February 9, 2019

For Birth Control "I am quitting this birth control immediately. I took Tri-Lo-Marzia for a month before I was switched to this for insurance. Both pills diminished my sex drive to where I almost never want it. Which is insane because before the pill I would want sex 4-5 times a week. Strangely enough, it has also made it incredibly difficult for me to get wet or orgasm... which I can't believe is even a thing. I've probably orgasmed once since taking it. After taking this pill, my face broke out so bad. I'm getting pimples in places I never thought I could. I just woke up with a pimple by my ear. This pill has made me very emotional. I have probably cried 10 times this month for the most stupid reasons. This pill has me fed up with birth control. It's not worth taking birth control if it's going to absolutely kill my sex drive and screw with my head and relationship. My review honestly sounds exaggerated, but this pill literally did all of those things to me."

2 / 10
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8 Report
  • Anonymous
  • October 31, 2013

For Birth Control "I'm 19, and started taking this pill because my boyfriend and I are pretty active and we use protection, but aren't necessarily fans of it. My doctor had advised me to continue using protection for at least the first month that I started the pill, and we did. I've been on the pill for almost 4 months now; no condom, no baby! The first month, I was an emotional wreck and completely lost my appetite. Now, I'm perfectly normal, haven't gained/lost any weight, my cramps are worse than ever the first 2 days of my period each month, my period still lasts a week but it's lighter, my libido has lowered, and I randomly get slight acne (I haven't had acne since I was 13 and I know it's the pill). Other than that, this pill fulfills its purpose and I'm very satisfied :)."

9 / 10
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14 Report
  • New...
  • March 7, 2014

For Birth Control "Was on Ortho Tri-Cyclen Lo 4 years ago for 2 years, kept a healthy diet, and exercised. Gained a little weight, but just on my girly parts! Very mild PMS, regular and moderate periods. Had a baby last year and used the mini pill for 9 months. Only been on Tri-Sprintec for 6 weeks, and right away I noticed side effects. It wasn't until I read some reviews that I realized I was getting hives from it. I have pretty bad allergies, so I thought that was why. I am a very optimistic person, and anytime I feel in a bad mood, I do anything/everything to come out of it. It seemed like I was constantly TRYING to pull myself out of a funk. Also, I noticed a decrease in appetite and libido. The positive is clearer skin, except for one recent breakout, it's FREE, and I'm not pregnant."

10 / 10
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14 Report
  • Sue...
  • Taken for 6 months to 1 year
  • January 6, 2020

For Birth Control "I’ve been on Tri-Sprintec for about 7-8 months now. I started after my second pregnancy (obviously to avoid a third) and kept putting off what I was feeling because I felt my emotions were related to postpartum, they most certainly were/are not. This pill causes hormonal disaster. I am cranky, quick to argue with my husband, have zero sex drive whatsoever, and cry over a messed-up order of huevos rancheros. I talked to my doctor about it, and she recommended switching pills because Tri-Sprintec is known for its side effects. I just want my body/mind back. This drug should not be marketed."

2 / 10
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8 Report
  • Han...
  • Taken for 2 to 5 years
  • July 29, 2019

For Birth Control "I started this pill when I was 16 for my acne. It was the first pill I ever took. It wasn’t until about a year or two later that I started to realize all the side effects I hadn’t noticed. I was tired ALL the time... like sleep 10 hours at night, wake up and take a five-hour nap after doing light activity kind of tired because I was drained. I lost all sex drive and arousal. This really took a toll on me emotionally because I was 18 years old and dry as a desert. I was a moody, miserable mess and couldn’t stop crying over literally anything. My acne slightly improved, but it’s hard to tell if it’s from the pill or my dermatologist visits. This pill did the bare minimum, it kept me from getting pregnant. Stay away from Tri-Sprintec, especially if you’re young."

3 / 10
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9 Report
  • EJF...
  • December 21, 2019

For Acne "Worst experience. Never had bad hormonal acne (initially took bc because of bumps on my chin and the side of my mouth), but this made my cheeks break out for months. I break out with hives when I have anxiety attacks - this made it worse. Became extremely angry, violently aggressive, irritable, zombie-like. Cried every day for the past year and a half. I'm young and married, but my libido was DEAD. No sexual desire for my husband. Actually made me feel VERY indifferent towards him. Suffered from severe depression before, and this year it hit me like a truck. No motivation, no energy, no drive. The past month has been the best month in just over a year - my skin somehow is the best it's ever been, and I can slightly control my emotions better. Still get angry and feel my body heat up. Still cry a lot. And still no sexual drive. Just started Microgestin yesterday, so hopefully, it's better than this."

5 / 10
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6 Report
  • Mel...
  • Taken for 1 to 6 months
  • January 2, 2020

For Abnormal Uterine Bleeding "I have been taking this for about 5 months and was previously on Trinessa for about 2 years with no complaints. I have started noticing that I am very moody and irritable almost daily and have zero motivation to do anything like going to the gym, going out with friends, or anything. I have also noticed that about a week or 2 before my period, I binge eat anything and everything as if I haven’t eaten in days. And then to top it off, I have zero sex drive now. I just do not have any interest in having sex, and it’s just not something I enjoy anymore. I had the best sex life with my boyfriend, and it’s just gone now. I’m on my last pills now and will not be taking them anymore and will see if anything changes."

5 / 10
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6 Report
  • Mel...
  • Taken for 1 to 6 months
  • January 2, 2020

For Abnormal Uterine Bleeding "I have been taking this for about 5 months and was previously on Trinessa for about 2 years with no complaints. I have started noticing that I am very moody and irritable almost daily and have zero motivation to do anything like going to the gym, going out with friends, or anything. I have also noticed that about a week or 2 before my period, I binge eat anything and everything as if I haven’t eaten in days. And then to top it off, I have zero sex drive now. I just do not have any interest in having sex, and it’s just not something I enjoy anymore. I had the best sex life with my boyfriend, and it’s just gone now. I’m on my last pills now and will not be taking them anymore and will see if anything changes."

5 / 10
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6 Report
  • Hal...
  • October 27, 2010

For Birth Control "I took Tri-Sprintec for 2 years while I had no insurance and couldn't afford anything else. On Tri-Sprintec, I experienced weekly migraine headaches, nausea, extremely heavy periods that lasted up to eight days, and horrible cramps that would leave me curled up on the couch and unable to go to school or work. All my life, I had experienced heavy periods, but it seemed to get worse on this. This is not including the terrible mood swings that almost drove me and my boyfriend apart. I hated myself, and it didn't help things that my sex drive was nonexistent. I am now on Loestrin 24 Fe and have had none of these side effects."

1 / 10
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13 Report
  • yel...
  • Taken for less than 1 month
  • January 7, 2016

For Birth Control "I normally take Tri-Linyah, but my pharmacy was out, so they gave me this because it is generic for it. I've been on it for less than a week, and my emotions are all over the place. All I do is want to cry, my anxiety is crazy high, and I am depressed. Low sex drive, headaches, horrible nausea. I have even experienced vaginal dryness. Very irritable and horrible mood swings. I've never had any of these issues before. I know medicine affects people differently, but I will not be taking this medicine anymore."

1 / 10
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8 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.