Tri-Sprintec and Anxiety: What Users Say

• Anonymous
• December 17, 2009

For Birth Control "Within the 1st week I went from a happy, optimistic girl, to a very unhappy, unstable individual. My experience: crying for no reason, complete misery, severe weight gain, antisocial, exhausted, nauseous, dry eyes, high anxiety, NO sex drive, painful sex, cramping, bloating, irrational behavior."

• Lil...
• June 7, 2016

For Birth Control "I have had absolutely no problems with Tri-Sprintec. I don't have any side effects at all. No weight gain, no mood swings, no depression, no anxiety, no nausea, same sex drive. (No increase in breast size either - I WISH I had that side effect!) I feel exactly the same taking this as I did not taking any birth control. The only difference is my periods are lighter and shorter, and my cramps are no longer severe. By the way, I was really scared to take this because of the negative reviews I read! But before you decide this is a bad pill, give it a try. Every woman's body is different, and your experience will just depend on your body!"

• Kai...
• Taken for 1 to 6 months
• February 10, 2020

For Birth Control "This birth control for me has only really done me a few favors, and that’s being free and not getting me pregnant. However, that being said, the side effects I can’t justify. I recently turned 18 and started taking the pill. My first month was fine, but the more I take it, the worse I’m getting. I’m having constant anxiety and panic attacks. I always feel extremely worried, stressed, and overwhelmed. I’m very irritable and impatient, not to mention it gives me horrendous headaches and recently extreme nausea and vomiting. Not to get into too much detail, but just absolutely projectile vomiting everywhere. Feeling very feverish, hot, and cold sweats, not to mention for period cramps, it does nothing. My cramps feel just as bad as they were before, and my period is just as heavy and maybe even a little longer. My sex drive has definitely decreased, and sex is painful, I nearly bleed a little each time. It’s causing me to go crazy, and I have trouble even sleeping with some of the symptoms."

• Anonymous
• Taken for less than 1 month
• May 1, 2020

For Ovarian Cysts "I just started this pill, Tri-Sprintec, 2 days ago for ovarian cysts, and I have high hopes for it. I went through so many doctors who told me everything was fine with me, but I knew something was wrong. Finally, I found a doctor that actually ran the blood tests for me and diagnosed me with PCOS. I’m 27, I can’t believe it took this long for someone to listen! Anyways! I was dealing with extreme anxiety and constant agitation for years, and starting this pill, I finally feel normal. Thank God! No mood swings and mini rages. I’m excited to finally have something that works for me!"

• J12...
• Taken for 1 to 2 years
• December 15, 2019

For Acne "When I first started taking Tri-Sprintec, it definitely was a struggle. I had some anxiety and depressive thoughts, and my acne only got worse. My gyno told me to wait longer than 3 months, and if I still felt crappy, to go back to her. After about the 4th month, things definitely started getting better. My acne began to clear up, my mental health went back to normal, and my periods got lighter, and my cramps were almost non-existent. My doctor told me Tri-Sprintec does have negative side effects in the beginning and does take a little longer for your body to get used to it. Overall, after the first few months, I am now very happy with this pill. I would recommend giving it a try and just to be patient with it. I know everyone is different, but it really works well after you give it time."

• Anonymous
• Taken for 2 to 5 years
• September 17, 2019

For Birth Control "The first year of being on Tri-Sprintec, I did great. The second year has been rough. Bad anxiety, depression, and I'm just so freaking tired all the time, some days it takes everything I can do to just make it through an 8-hour shift and make it back to my bed. I've always been a very energetic person until this past year. I also haven't had a sex drive in forever, it seems like. And these mood swings, I can't even deal with. I've really been struggling the past year. Never really thought that it was the birth control doing all these crazy things to me."

• Coo...
• March 13, 2019

For Birth Control "Increased depression and headaches all the time. Got rashes around my face and broke out really bad. Anxiety and mood swings off the roof. Still have cramps and gained so much weight. No sex drive whatsoever and feel nausea all the time."

• NTL...
• Taken for 5 to 10 years
• March 15, 2013

For Acne "I started taking Tri-Sprintec when I was 17. I am now 24. This was originally recommended to me by my OBGYN for acne and migraines, and it has made my skin great and migraines disappear. Occasional breakouts, but nothing major. In the beginning, I had no major emotional, weight, or period issues. My periods are still very light and last about 5 days. After a few years, my weight spiraled out of control, and I ended up gaining about 45 pounds (from 122 to 160!) and also dealt with depression, anxiety, low energy/lethargy, and increased appetite. Every body is different, which is why it is important to monitor your symptoms over YEARS. Things can change. I am now switching to a lower dose of hormones and seeing if there is a change."

• sch...
• Taken for 1 to 6 months
• April 17, 2014

For Birth Control "I had a baby girl 6 months ago, and I started this about 2 months ago. At first, I was doing great with it, but then, after about 2 weeks of taking it, I have really noticed some not-so-great changes in me. My chin is constantly breaking out, so it did not help clear up the acne. I have really had some bad mood swings of just feeling really sad, and my anxiety has been pretty bad. It has really messed with my sleeping patterns. I also gained about 16 lbs from the time I started taking this pill until now. I wear contacts, and it really seems to dry my eyes out and make my vision a little blurry, which I haven't really had much trouble with before. I am seeing my doctor soon, and we are planning on switching me to another birth control pill."

• Sop...
• Taken for 1 to 6 months
• May 14, 2019

For Acne "I was forced to switch over to Tri-Sprintec because they discontinued Tri-Nessa Lo. I have never had worse acne in my entire life. If I had read these reviews previously, I would not have taken it. The pharmacy said it was 'pretty much the same.' It is not, I should have been put on the Tri-LO-Sprintec. There are two different strengths of the Tri-pills, the low and the higher one. They changed me to the higher one. This medication has caused my depression and anxiety to spike in extremes. I have never experienced cystic acne until now. Full coverage makeup cannot hide the embarrassment I've been feeling in public for months. I've taken it for 3 months, and it's been 3 days since I officially stopped."

• Anonymous
• May 9, 2019

For Birth Control "I was a huge fan of Trinessa. I was on it for a year and a half with no issues and no side effects. I stopped taking it for about 6 months because I was no longer in a relationship and just wanted to see if anything changed (weight, skin, mood) if I got off the pill. I decided to start taking it again just to keep my periods more regular and because I forgot how terrible my cramps are without birth control. I went to my pharmacy and got a refill and noticed they discontinued Trinessa and was given this Tri-Sprintec stuff instead. I’m almost at the end of my second week taking it, and it is terrible, nothing like Trinessa. I’ve had weird stabbing pains in my left breast, I’m tired 24/7, my anxiety has been awful, I’ve had no appetite, and my stomach has constantly been upset, and I’m so depressed that I barely want to get out of bed. If you were previously on Trinessa and liked it, do not get this. I’m going to have to try and find a better Trinessa equivalent now."

• SGa...
• Taken for 1 to 6 months
• January 16, 2020

For Acne "Oh my goodness. I am in tears reading these reviews, finally finding out what’s wrong with me. I stopped breastfeeding about 3 months ago, and my skin started to break out from the hormone change, as expected. I called my OB to get back on what I assumed would be my regular BC, Trinessa, but I got this Tri-Sprintec. My face has never been this bad in my entire life. Painful, cystic acne. I’ve gained weight. My mood swings were terrible. I had anxiety through the ROOF. Whatever you do, DO NOT GET ON THIS PILL."

• Ema...
• Taken for 1 to 6 months
• March 29, 2019

For Birth Control "Been on this for about three months since they discontinued Trinessa and forced this pill on me, and let me tell you, this has easily been the worst three months of my life. I need birth control to keep me regular and keep my skin clear (which this pill is only okay at doing), but it is not worth the mental damage this pill is doing to me. I’m fine the first two weeks, but as soon as I start week three, I feel like I’m going crazy! I cry over everything and panic and become so anxious I need anti-anxiety meds, and I even have extreme dark thoughts. As soon as I finish this pill pack, I’m done for good because this is not worth it, it’s ruined all of my personal relationships and motivation for even succeeding in school. (Writing this on the first day of week three in case you were wondering)"

• Tan...
• November 14, 2019

For Birth Control "Started the Tri-Sprintec pill about 3 months ago, and it’s one of my biggest regrets. I should’ve listened to the reviews. I experienced horrible anxiety, my depression has been at an extreme low, crazy nervous sweats, nausea, loss of appetite, and last but not least, the mood swings. I’m usually a pretty chill person, aka not usually moody. So this was different for me. These pills really messed me up. That’s my honest review."

• Nic...
• February 2, 2017

For Birth Control "I've waited out the three-month wait time of absolute hell. Since starting Tri-Sprintec, my anxiety is through the roof, which exacerbates my depression to the point of me having suicidal thoughts on a daily basis. I can't wait to see my doctor and switch to a new pill. At 25 years old, my acne had subsided from the teenage years, but since I was started on Tri-Sprintec, it has come back. I thought maybe it would just come and go around the time of my period. Nope. Still here and even more coming in. I feel like I am back to being a teenager again with this acne and crazy mood swings. I am crying over anything and everything. Maybe these side effects will go away in more time, but I can't handle this any longer to find out."

• lal...
• August 25, 2015

For Birth Control "While Tri-Sprintec is effective at preventing an unwanted pregnancy, it has the worst side effects I have ever experienced on a birth control pill. I've only been on it for a little over a week and I have to stop using it. It has given me excruciating stomach aches, nausea, fatigue, migraines, and worst of all, it is aggravating my anxiety levels. I feel like I'm on the verge of having a major panic attack since I started taking this awful pill. Not only is my anxiety getting out of control, but I also feel depressed and uninterested in everything. All I want to do is sleep. I wish my stupid insurance covered Ortho Tri-Cyclen Lo, that has been the best pill so far. I don't recommend Tri-Sprintec to anyone."

• Jan...
• Taken for 1 to 2 years
• November 7, 2019

For Birth Control "While my periods were consistently on time and my skin cleared up, this pill made me feel stressed, depressed, and 'crazy' all of the time. It also caused me headaches, migraines, and a general unwell feeling."

• Sky...
• Taken for 1 to 6 months
• September 28, 2020

For Birth Control "This pill wasn't bad at first, helped my periods, only bled through once, some headaches right before my period, helped the little bit of acne I had, and nauseous every now and then. I felt good after my body got used to it after 4 months. But now I am super anxious all the time, hard to sleep because of the anxiousness, very paranoid, and just ready to cry because I'm so overwhelmed it seems. Generally a happy person, but the anxiety it has caused me is awful. Going to try another pill, hopefully much better than being anxious."

• Kay...
• Taken for less than 1 month
• July 2, 2019

For Abnormal Uterine Bleeding "I have had irregular periods, but recently in May, I had a period for about 3 weeks, and I was tired of it. So I went to the doctor and was told Tri-Sprintec would help. I started taking it at the beginning of June and have been on it for almost a month now. With no luck, I’m still bleeding constantly. I continued the pill to see if the bleeding would eventually stop, but unfortunately, it hasn’t. During the first week, I received loss of appetite, extreme anxiety, night sweats, depression, and nausea, and the side effects still occur. I’m going to finish the pack because hopefully, I’ll receive some luck, but I do not plan to continue this pill after this first pack."

• Sue...
• Taken for 1 to 6 months
• April 20, 2019

For Birth Control "I was given Tri-Sprintec after my usual prescription of TriNessa was discontinued. I had the normal side effects such as nausea, cramping, and a change in period the first few weeks, but that was nothing compared to the anxiety and depression it caused the longer I took it. By the end of the second month, I was crying every day and had horrifying intrusive thoughts. I finally had to make an appointment with my doctor, and she told me to stop taking it and gave me an antidepressant to ride out the lingering effects until it leaves my system. 10/10 would not take again. I seriously miss TriNessa."

• win...
• August 31, 2015

For Birth Control "This pill did horrible things to me. I felt nauseous constantly and experienced severe anxiety. So much so, that I could not leave the house without crying. I was depressed and gained 8 pounds. All of this in less than a few months. I finally went off Tri-Sprintec when I realized that it was causing me these side effects. Absolutely terrifying experience."

• yel...
• Taken for less than 1 month
• January 7, 2016

For Birth Control "I normally take Tri-Linyah, but my pharmacy was out, so they gave me this because it is generic for it. I've been on it for less than a week, and my emotions are all over the place. All I do is want to cry, my anxiety is crazy high, and I am depressed. Low sex drive, headaches, horrible nausea. I have even experienced vaginal dryness. Very irritable and horrible mood swings. I've never had any of these issues before. I know medicine affects people differently, but I will not be taking this medicine anymore."

• Kan...
• Taken for 1 to 6 months
• December 3, 2018

For Birth Control "I am going on month 3 of using this birth control, and yes, it works. But it is so not worth it because of the side effects. I already have anxiety, so this birth control has not only made it 10 times worse but has made me extremely depressed and given me insane mood swings that I can only describe as bouts of rage. I have never felt this emotionally unstable in my life. I have also gained around 5-10 pounds. However, this is the cheapest I can get birth control without insurance, so if the side effects don’t end up wearing off, then I will definitely go off of it."

• Can...
• Taken for 2 to 5 years
• March 17, 2017

For Birth Control "I have been on Tri-Sprintec for nearly 5 years. As far as preventing pregnancy, it's worked great. It also made my periods lighter. The last week before my placebo week has always kind of made me have mood swings. However, for about the past year, it's unbearable. Every third week of the month, I get severe depression, anxiety is through the roof, which then leads to insomnia and a constant feeling of dread. Nothing has changed in my life that would lead to any of this. I have narrowed it down to the birth control. I'll be switching ASAP."

• Can...
• Taken for 2 to 5 years
• March 17, 2017

For Birth Control "I have been on Tri-Sprintec for nearly 5 years. As far as preventing pregnancy, it's worked great. It also made my periods lighter. The last week before my placebo week has always kind of made me have mood swings. However, for about the past year, it's unbearable. Every third week of the month, I get severe depression, anxiety is through the roof, which then leads to insomnia and a constant feeling of dread. Nothing has changed in my life that would lead to any of this. I have narrowed it down to the birth control. I'll be switching ASAP."