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Esomeprazole User Reviews & Ratings (Page 4)

Brand names: Nexium, Nexium 24HR, Nexium IV

Esomeprazole has an average rating of 6.0 out of 10 from a total of 260 reviews on Drugs.com. 50% of reviewers reported a positive experience, while 36% reported a negative experience.

Reviews for Esomeprazole

  • Elena
  • March 6, 2010

Nexium (esomeprazole) for GERD "Diagnosed with acid hitting my throat (LPR). Have a small stomach hernia that is not allowing sphincter to close. It was a rough 6 months till I was diagnosed. 3 doctors insisted I had allergies. Found another doctor that finally advised I had 'silent acid reflux.' Have cut out all the usual foods that cause more acid, but in my case, my ears hurt (they tell me you have lots of nerves through the throat that go up to the ears and sinuses). Symptoms are: burning ears, flaring up through the sinuses, pain in the back of the neck up through the top of the back of my head. Have been on Nexium for 3 months. It helped, but flaring returns 10-50%. Have come off Nexium to do the tests on how my GI is working. Nexium helped, but lots of side effects."

6 / 10
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  • impac...
  • Taken for less than 1 month
  • January 8, 2016

Nexium (esomeprazole) for Erosive Esophagitis "I have been with horrible chest pressure for the last 2 weeks. Impossible to sleep. I have lost around 6lb, today I went to the doctor office and she send me Nexium. She tells me I have esophagitis. With just the first pill, all my pains have disappeared! I hope it continues this way, as I can enjoy life again."

10 / 10
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28 Report
  • Johnin...
  • Taken for 1 to 2 years
  • November 9, 2014

Nexium (esomeprazole) for GERD "I have been using Miralax and psyllium every night for about a year and wanted to try Linzess, but my doctor was hesitant to let me try it. Possible side effects. Anyway, after some research, I realized the Nexium I have been using causes a magnesium deficiency. So now I take a multi-mineral capsule and a 500 mg magnesium capsule three times a day with meals. I have been able to cut back on my prescribed medications and have some hope that I will be able to get off them completely by adjusting my mineral intake. Try this because your bowels cannot function without enough minerals."

4 / 10
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31 Report

Frequently asked questions

  • LPRguy
  • Taken for less than 1 month
  • March 7, 2022

Nexium (esomeprazole) for GERD "I was diagnosed with Laryngopharyngeal reflux (LPR) in 2018, in my mid-40s. This surprised me because I had zero problems with reflux in my life, and in fact never experienced heartburn ever. The doctor advised I take Nexium for my LPR, as well as abruptly cut out caffeine. The result was disastrous. I abruptly developed a crippling anxiety, depression, and anhedonia (lack ability to feel pleasure) problem, about a week later. I never had any of these conditions prior to taking Nexium and cutting out the caffeine! After about a few weeks, I tried quitting first the Nexium and then later bringing back the caffeine. A few days after doing both, my psychological condition rapidly improved. However, at the time I attributed my issues being from caffeine withdrawal, and not the Nexium. Wrong! I ended up being given Nexium again for something different, and the anxiety started to return! I quickly quit it, and went back to normal. If it makes you feel anxious, quit it now!"

1 / 10
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  • Cherr...
  • Taken for less than 1 month
  • October 21, 2016

Nexium (esomeprazole) for GERD "I took Nexium for all of three days. In that time I found it to be extremely effective in managing my reflux/stomach symptoms. However, within a day I noticed severe anxiety surfacing. I take Aropax (paroxetine) for depression and this is not on the list of medications that is counterindicative. I do note that being magnesium deficient is but my doctor would not care enough to know that I have always had this deficiency. I do not normally suffer from headaches but began to have gentle pains in my head, getting worse over the time. The head pain and anxiety lasted as long as the effect on my stomach which was a number of days after I stopped taking the medication."

3 / 10
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25 Report

Are you taking this medicine?

  • Riot
  • Taken for 5 to 10 years
  • May 8, 2018

Nexium 24HR (esomeprazole) for GERD "Asthma Physician prescribed Nexium 40mg for me after I needed to use my asthma inhaler 4 times a day. Over time, I was diagnosed with long standing Hiatal Hernia and GERD. I continue to use Nexium to manage my breakthrough Reflux and the result has been wonderful for me, save for occasional nuisance bloating. Thanks."

9 / 10
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  • BruceA
  • November 10, 2014

Nexium (esomeprazole) for Barrett's Esophagus "Prior use of prescription Prevacid did not provide relief for 24 hrs. 1/day 40mg Nexium provides about 30 hr no acid sensations. My only side effect of Nexium is my stool usually has the consistency of peanut butter."

9 / 10
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29 Report
  • Gerdg...
  • Taken for less than 1 month
  • July 10, 2021

Nexium (esomeprazole) for GERD "I took this 20mg twice a day as recommended by my doctor) and within 4 days I had palpitations, insomnia, extreme anxiety, dizziness, nausea and pins and needles in my neck and legs. Worse was at night when trying to lie down when there would be pressure in my head and chest and violent dizziness and nausea. I had two weeks of only sleeping 2 hours a night and peaked with 2 successive nights of no sleep and a visit to Accident & Emergency. Suddenly realised it was the tablets and stopped the, effects slowly going and sleeping at last."

1 / 10
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12 Report
  • Anonymous
  • February 12, 2012

Nexium (esomeprazole) for GERD "I have had GERD since I was 19 years old. For some reason, I eat ketchup with everything. I am 31 now. I've used Nexium in the past, and my acid reflux always went away. Recently, I've had upper back pains, cold chills, stomach and heartburns, and the worst belly pain ever after I ate. The doctor sent me for a blood test, which came back negative for any infections. I was placed on Nexium. Within 2 days, I felt much better. I would recommend this for anyone. Wish I had tried it before I did the ultrasound of my kidney, liver, and gallbladder, together with a chest X-ray. I guess you've got to pay a high price for a good product like Nexium. But I don't mind. I feel much better now."

10 / 10
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  • KPano
  • Taken for less than 1 month
  • October 12, 2019

Nexium (esomeprazole) for GERD "I was prescribed this for possible stomach ulcer and GERD. Within 30 minutes of taking this I had sharp chest pains when inhaling. The ER dr said it was a panic attack- it wasn’t, not my usual panic attack symptoms. My Dr told me I was her second patient to experience that with the drug. Never took it again. Was then prescribed Zantac with out issues, but it is being recalled now. Not sure what else to take besides Tums."

3 / 10
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  • Plant...
  • Taken for 1 to 2 years
  • June 14, 2020

For GERD "I have tried many different medications for persistent heartburn and GERD for the last 20 or so years. Started with Tagamet (cimetidine), which helped, but not consistently. Switched to Prilosec (omeprazole) 40mg/day about 10 years ago. Also inconsistent (and I follow an anti-GERD diet out of necessity, and still suffered from sometimes debilitating heartburn and related digestive issues. When Nexium finally went generic (it was just too expensive before) I switched to that, taking two 40mg capsules/day, and it changed my life. This is a very high dose but I was completely desperate for relief, which I got within days. I never get flareups since starting on it, so for me it’s a wonder drug. I’m also well aware of the controversy around PPI’s, but luckily I have not suffered any side effects and take B12 and iron supplements, in addition to a multivitamin daily. I hope to eventually come down to one capsule/day instead of two, but for now that’s what works best."

10 / 10
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  • Smittie
  • Taken for 10 years or more
  • November 10, 2016

Nexium (esomeprazole) for Barrett's Esophagus "I've taken One Nexium 40mg for 13 years . It has been very helpful. Could only eat baby food when diagnosed. When my health insurance said I had to use the Generic Brand I tried it for five days, began having very bad episodes of heart burn. They have agreed to pay for the name brand."

10 / 10
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  • Elfling
  • Taken for 2 to 5 years
  • November 16, 2016

Nexium (esomeprazole) for Duodenal Ulcer Prophylaxis "I was prescribed Nexium 40mg approx 2 years ago at our local hospital after being diagnosed as having a quantity of small duodenal ulcers. No side effects were evident for the first week or so but then I started to feel aches and pains all too easily, later developing mood swings, quite extreme at times. I informed my doctor who dismissed my claims,( I do not lie! )After just under the two years of taking Nexium, I decided to take things into my own hands, I discovered Slippery Elm capsules. I am now into my fifth month of taking only one capsule a day having weaned myself off the Nexium, interspersed with Slippery Elm in the first week. I now have no side effects and with care have little or no acid indigestion."

7 / 10
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  • sajjad
  • August 10, 2011

Nexium (esomeprazole) for Helicobacter Pylori Infection "Best for curing H. pylori. Nexium 20 mg half an hour before breakfast and half an hour before dinner. Also, my doctor suggested I use Frisium only at nighttime before sleep. Within 2 days, I started feeling better, and I used it for 1 month, but Frisium I only took for one week."

10 / 10
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  • Paul...
  • March 8, 2015

Nexium (esomeprazole) for GERD "I suffered severe pain from GERD that I had to be hospitalized. The next day I bought the Nexium 24hr, not because I saw it was the top selling brand at Walmart, but because my mom said to get Prilosec lol. Anyway, within minutes the pain from my GERD disappeared. One con I've had so far though. The medicine states 24hrs, for me it's roughly 18-20 hrs and I start feeling the acid again. So keep that in mind."

10 / 10
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  • Bbwasil
  • Taken for less than 1 month
  • December 24, 2016

Nexium (esomeprazole) for GERD "I have a severe acid reflux and my doctor recommended Nexium. I took it only 5 days and experienced no difference whatsoever. Absolutely no change. I still have severe acids and to be honest the drug seemed to make my symptoms worse. As well I am 100% sure it interacts with antidepressants and lowers their effectiveness! So if you are taking SSRI, please be aware!"

1 / 10
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21 Report
  • Anxie...
  • Taken for less than 1 month
  • November 12, 2021

Nexium (esomeprazole) for GERD "After having heartburn my doctor just automatically prescribed this to me. Let me tell you something! This is the worse thing I could’ve put in my mouth. My anxiety was off the roof! I ended up in the ER because I thought I was having a heart attack. I’ve always suffer from anxiety but this time it’s worse. Burning palm sensation, weird sensations in my brain along with pressure. My vision feels foggy and blurry, and I have arm and leg pain, and depersonalization. The list goes on. It’s been almost a month and I’m still suffering. I feel terrible. I wanted to quit my job and stay in bed! Although this may work for others. It can have bad effects on some. Use with caution!"

1 / 10
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10 Report
  • RMM
  • Taken for less than 1 month
  • October 11, 2021

Nexium (esomeprazole) for GERD "Please be aware that this medication can cause anxiety, depression, and suicidal thoughts. Supposedly, it is a rare side effect, but I don’t have any allergies and I’ve never reacted to a medication like that before. When I was 19 years old (now 28) I had major stomach issues. I was diagnosed with gastritis and given this medication. I will never forget how it made me feel. I never want to feel like that again. I stayed up all night crying and staring out the window wishing I could just leave this world. I’m normally a very happy and content person. I will never ever take Nexium again. My doctor was able to give me another medication that made me better but I can’t remember what it was called. I only remember Nexium because of how horrible it was. The best way to describe it is Nexium made me feel like I was going crazy."

1 / 10
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10 Report
  • Bry
  • Taken for less than 1 month
  • August 24, 2019

Nexium (esomeprazole) for GERD "I had two months of daily awful heartburn. I wasn't eating the best and I was drinking alcohol. Well, that part didn't stop, but I did take Nexium. It was amazing. During the 14 days I lightened my diet but still ate the things I enjoyed. I'm 35, and I think this is my first "medication" review, lol."

10 / 10
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15 Report
  • molly
  • Taken for 10 years or more
  • January 24, 2020

For GERD "I have been taking the generic of nexium for about 10 years, every day, and have had no problems what so ever, but I take no other meds. I am 77 yrs old. Hope this helps others, if they are wondering if they can do this."

10 / 10
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14 Report
  • Leeanne
  • November 11, 2020

Nexium (esomeprazole) for GERD "Beware of their marketing scam. I called the phone number on their marketing add on tv. I asked for a trial and the person said I would be charged a shipping fee of $7.95 . I said that was fine . They charged me $7.95 on Oct. 4th. On Oct 21st. I was charged $119.90. I did not receive the product until Oct. 30th. I called nexium and complained about the charge. They said, “I needed to call 14 days after trying the product to cancel the agreement”, I was not aware of any agreement because I only asked for a trial, and besides, I received the product 9 days after I was charged $119.90. How was it possible for me to try the product in 14 days to cancel the agreement that was not explained to me. They charged me even before I was able to try the product. Nexium did not work. I took it for 3 nights and stayed up all 3 nights! This is really a scam and I am disputing it."

1 / 10
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12 Report
  • Ashle...
  • July 28, 2015

Nexium (esomeprazole) for GERD "I have now been using Nexium 24 for only 4 days but I am seeing the effects already! I have been able to enjoy many foods I have had to avoid in the past with little to no burn. I absolutely have hope that Nexium is the answer to all my problems and that in time it will eliminate the problems all together. I was lucky enough to receive my Nexium free from a mission and now I'm a dedicated customer. Thank you so much for this awesome product!"

10 / 10
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23 Report
  • Xerk
  • Taken for 6 months to 1 year
  • December 22, 2019

For GERD "This medicine is toxic. After weeks of stopping my medication, I now have. 1. Muscle twitching 2. Nerve problems 3. Back, legs, shoulder pains (although my leg and shoulder pain have decreased) 4. Weight loss (I managed to recover my lost weight). 5. Vision problems (Although I think it has something to do with a wrong prescription glasses) 6. Anxiety / Panic Attacks I do not recommend taking this drug. If you want to reduce your stomach acid, I recommend Gaviscon and other antacids. NEVER USE PPIs."

1 / 10
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14 Report
  • Nikki
  • Taken for less than 1 month
  • January 3, 2022

For Gastritis/Duodenitis "I have an anxiety disorder and was prescribed this a few days ago for acid reflux. I feel like my anxiety has gone through the roof, I feel terrible and I'm wondering if it is this drug now that I read all of your comments! I will stop it immediately. I have fast heartbeat, shaking and hand are hot, and a headache. :("

1 / 10
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9 Report
  • Abba
  • November 4, 2018

Nexium (esomeprazole) for GERD "I just want to say that if you have GERD and have a history of aspiration pneumonia, Do Not replace rxnexium 40MG with the OTC 24hr Nexium. They Are Not The same, after my mother wanted to try the otc Nexium for a few months, she developed Aspiration pneumonia after not having it for many years (10), she passed away"

10 / 10
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16 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.