Skip to main content

Esketamine and Sick: What Users Say

Brand names: Spravato

Sick: mentioned by 5 users (3.7%)

Based on user experiences from 135 Esketamine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 11.1%
anxiety 8.1%
dizziness 6.7%
hallucinations 5.9%
bad taste 4.4%
headaches 4.4%
confusion 3.7%
depression 3.7%
drowsiness 3.7%
sick 3.7%

Reviews for Esketamine

  • MIS...
  • October 31, 2020

Esketamine for Depression "I have mixed feelings about this drug. This has taken the suicidal thoughts and squashed it. My depression is very little. I really don't like the treatment - feeling spaced out for 45 mins. I've had high heart rate, dizzy, sickness, headaches. The BIGGEST most important part of this treatment is to take no medications the night before and day of treatment, don't drink the night before or you will pay for it with super sickness, panic attacks, and high heart rate. Everyone is different with this treatment, don't think it's going to be fun because it's not. But versus being dead, it was worth the try! I had to find this out on my own, the doctors don't tell you much about what and what not to do when you take this medication. Most important, put yourself in a calm state during, I found playing soft music is a must, and try not to get up during, or it will cause you to be dizzy and sick. Wait at least 45 mins after when it wears off. I hope this helps someone."

7 / 10
Was this helpful?YesNo
183 Report
  • Mic...
  • Taken for 1 to 6 months
  • January 22, 2020

For Depression "I started taking Spravato nearly two months ago. Started at the 56 mg loading dose. At four weeks, it had done nothing positive. So the doc upped it to the 84. First off, that first double-dose treatment had me on one hell of a trip. I really felt that I wasn’t coming back! After that treatment, I was hungover, then treatment 2. After that, I was sick as a dog. Severe headaches and terrible nausea. Took me 5 days to recoup, and as of today, still with the headaches and nausea. Called the doc and stopped treatment altogether. I just can’t spend day after day feeling sick, not able to work, etc. This was a last-ditch effort, and now I don’t know just what I am going to do."

1 / 10
Was this helpful?YesNo
14 Report
  • San...
  • Taken for 1 to 6 months
  • June 27, 2019

Esketamine for Depression "I'm on Spravato, and the 56 mg dose is too much. Sick for 4 days after. Then 1 or 2 OK days. Where are all the other reviews? Doctors know all that I know. They are no help at all."

2 / 10
Was this helpful?YesNo
35 Report

Frequently asked questions

  • Alb...
  • Taken for 1 to 6 months
  • March 7, 2022

Esketamine for Depression "8 treatments at 28 mg, last two treatments felt terrible during and 3 days after, can't sleep and feel sick. Went up to 54 mg, sickly past 4 days, can't sleep. This is horrible medicine."

1 / 10
Was this helpful?YesNo
12 Report
  • Alb...
  • Taken for 1 to 6 months
  • March 7, 2022

Esketamine for Depression "8 treatments at 28 mg, last two treatments felt terrible during and 3 days after, can't sleep and feel sick. Went up to 54 mg, sickly past 4 days, can't sleep. This is horrible medicine."

1 / 10
Was this helpful?YesNo
12 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.