Xtandi and Tiredness: What Users Say

• jlm...
• April 18, 2016

For Prostate Cancer "4 months at 160 mg each day and 1 month at 120 mg a day. PSA was 48 when starting this medicine. PSA dropped to 0.20! Medication did its job. BUT, side effects were extremely painful, tiring, hot flashes, losing my balance, and so much more. I'm 83 years old and had stage 4 prostate cancer. If I get 4 more years or so, it's worth it. Have been off medicine for about 3 months and still having side effects! Rating would be 8."

• Gie...
• Taken for 2 to 5 years
• June 29, 2020

For Prostate Cancer "The cost of Xtandi is ridiculous, in my opinion, but the options are 0 at this time. My PSA went up to around 50, and I was on Lupron. I was then put on Xtandi, and for almost 4 years, my PSA has been below 1. Side effects, I would say, seem to be tiredness. I also seem to be picking up weight in my legs and around my stomach, but have not gained any pounds since being on the Xtandi. I would have to qualify this as a success with side effect limitations."

• Ray...
• Taken for 1 to 6 months
• May 25, 2022

For Prostate Cancer "My 88-year-old dad was put on Xtandi combined with hormone shots for prostate cancer (returned after 10-year remission). I questioned this since his PSA dropped a lot after just one injection. The doctor felt it was needed to ensure the cancer didn't metastasize. He has been on Xtandi for about 5 months, and I've seen an alarming decline in his overall health. He's gotten so weak that he fell yesterday and couldn't even get himself up. He's having bad back pain, lethargy, sleeping long hours, general malaise/unconcern, loss of appetite, moving at a very slow pace, and now falling. We're taking him off Xtandi. While it's an antiandrogen, it seems to work like chemotherapy! It 'might' be effective (can't really say), but I don't think it's worth the chance he's taking. I just pray all the harm (even more than listed here) this drug has done in this short time will reverse. I'm scared, given another review here, though, that the damage will be permanent. Time will tell... only God can heal."

• Gar...
• Taken for less than 1 month
• April 25, 2023

For Prostate Cancer "78 years old with stage 4 prostate cancer. I'm on an Eligard injection to my belly fat every six months. PSA has been at point 3 (.3). Was put on Xtandi in addition to Eligard after not being able to tolerate Erleada because of bad headaches and extreme tiredness every time I took it. Had to stop Xtandi after two weeks because of extreme back pain between my shoulder blades that burst across my back if I coughed. I'm done with the add-ons due to quality-of-life issues. Will just stay with Eligard and take my chances."