Xtandi and Back Pain: What Users Say

• Tat...
• Taken for 1 to 6 months
• January 21, 2019

For Prostate Cancer "My 69-year-old dad is taking Xtandi for 3 months now. The first month was perfect, PSA went down from 275 to 180, and he was feeling amazing and healthy. At the end of the second month, he started to get pain in his lower back, very burny skin, and he could not even sit. After 2 weeks, he suddenly could not walk anymore on one leg. So he stopped Xtandi for 14 days. In this time, he was able to walk again. Very weak, but slowly walking. But his PSA is now back to 276. He has started Xtandi again. He has stage 4 prostate cancer. Wish him luck. I believe this drug may work very well but can have terrible side effects!"

• Ray...
• Taken for 1 to 6 months
• May 25, 2022

For Prostate Cancer "My 88-year-old dad was put on Xtandi combined with hormone shots for prostate cancer (returned after 10-year remission). I questioned this since his PSA dropped a lot after just one injection. The doctor felt it was needed to ensure the cancer didn't metastasize. He has been on Xtandi for about 5 months, and I've seen an alarming decline in his overall health. He's gotten so weak that he fell yesterday and couldn't even get himself up. He's having bad back pain, lethargy, sleeping long hours, general malaise/unconcern, loss of appetite, moving at a very slow pace, and now falling. We're taking him off Xtandi. While it's an antiandrogen, it seems to work like chemotherapy! It 'might' be effective (can't really say), but I don't think it's worth the chance he's taking. I just pray all the harm (even more than listed here) this drug has done in this short time will reverse. I'm scared, given another review here, though, that the damage will be permanent. Time will tell... only God can heal."

• Gar...
• Taken for less than 1 month
• April 25, 2023

For Prostate Cancer "78 years old with stage 4 prostate cancer. I'm on an Eligard injection to my belly fat every six months. PSA has been at point 3 (.3). Was put on Xtandi in addition to Eligard after not being able to tolerate Erleada because of bad headaches and extreme tiredness every time I took it. Had to stop Xtandi after two weeks because of extreme back pain between my shoulder blades that burst across my back if I coughed. I'm done with the add-ons due to quality-of-life issues. Will just stay with Eligard and take my chances."