Skip to main content

Xtandi and Hot Flashes: What Users Say

Hot flashes: mentioned by 4 users (18.2%)

Based on user experiences from 22 Xtandi reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 18.2%
hot flashes 18.2%
tiredness 18.2%
back pain 13.6%

Reviews for Xtandi

Commonly mentioned side effects
  • Spa...
  • Taken for 1 to 2 years
  • June 14, 2019

For Prostate Cancer "Apparently, have stage 4 prostate cancer. Had radiation, no surgery; went on Lupron for 2 years. Prescribed term ended and then PSA climbed in 3 months from 0.23 to 4-ish. Back on the Lupron. PSA dropped at first, then climbed to 6.4. Started Xtandi (simultaneously on Lupron) almost 2 years ago. PSA rapidly dropped to below 0.02. Been there ever since. No change in side effects from being on Lupron alone: Hot flashes (fewer and less severe over time) and weakness when they occur. Last 30' to a couple of minutes. For me it seems like a miracle drug."

10 / 10
Was this helpful?YesNo
87 Report
  • jlm...
  • April 18, 2016

For Prostate Cancer "4 months at 160 mg each day and 1 month at 120 mg a day. PSA was 48 when starting this medicine. PSA dropped to 0.20! Medication did its job. BUT, side effects were extremely painful, tiring, hot flashes, losing my balance, and so much more. I'm 83 years old and had stage 4 prostate cancer. If I get 4 more years or so, it's worth it. Have been off medicine for about 3 months and still having side effects! Rating would be 8."

9 / 10
Was this helpful?YesNo
101 Report
  • Ric...
  • Taken for 2 to 5 years
  • May 4, 2022

For Prostate Cancer "I'm a 63-year-old male who was diagnosed with Stage 4 prostate cancer and started on Casodex/Lupron. It was good, but Casodex stopped working after 6 months. I was switched to 160 mg of Xtandi. Dropped my PSA pretty quick, side effects were pretty rough to start with (memory, brain fog, balance issues, hot flashes). After 6 months, the doctor lowered the dose to 80 mg, and side effects lessened. Brain fog reduced greatly, hot flashes and balance issues come and go. PSA has been non-detect for over 2 years now. I also take multiple natural supplements that I have researched. These supplements reportedly block the feeding pathways of my cancer. They can also help extend the effectiveness of the Xtandi. Do your research because the doctors don't look at anything natural. Also, change diet and limit carbs to 75 gm / sugar 40 gm or less. Lots of vegetables, a whole lot less meat. I have to say, I'll put up with the side effects as this drug really works."

10 / 10
Was this helpful?YesNo
23 Report

Frequently asked questions

  • Doc...
  • Taken for 2 to 5 years
  • November 8, 2021

For Prostate Cancer "I've been on Xtandi since May of 2019, along with a shot of Leuprolide every 3 months. I have been taking 4 - 40 mg capsules each day. My PSA almost immediately dropped to below measurable and has remained there. Side effects have been brief hot flashes, aggravated when I get in a warm room, some loss of muscle mass, and loss of taste so that favorite foods are no longer enjoyable. I do taste salt and sweet. I am 75, maintain a relatively active lifestyle, and consider my side effects minimal. I had high-risk prostate cancer and underwent a robotic prostatectomy along with adjuvant radiation. I started the Xtandi following the surgery."

10 / 10
Was this helpful?YesNo
20 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.