Dupilumab for Asthma, Maintenance User Reviews (Page 2)

• Red...
• Taken for less than 1 month
• May 8, 2021

"I had my first 2 injections for my asthma. I really needed it to work, I need to get off inhaled steroids. I've been on the strongest dose of Advair, 4 puffs a day for 19 1/2 years. I started having reactions in my eyes the next day. It’s been weeks and not at all better. Red, sore, lump, burning. I’m now on steroid eye drops. Now applied for Nucala. Hope that works!!!!"

• KDB...
• December 12, 2021

"I’ve been using Dupixent for over 2 years, and “yes,” it does work on my asthma, but I still cannot understand why it burns so much going in. It feels like fire is going in. But I can’t stop using it. Recently, my company changed our insurance company, and there was a 4-week stoppage. After missing Dupixent for just one dose, my asthma kicked in, and I was in trouble for those weeks off the drugs. My Trelegy helped out a lot, but I strongly recommend using this drug for asthma and for those who are battling with COPD. It really does work."

• msv...
• Taken for 1 to 2 years
• May 19, 2021

"Dupixent has decreased my asthma symptoms drastically, and I have had less severe asthma attacks and less eczema flare-ups. I am 130 lbs, 19 y/o, female. The side effects for me include acne breakouts, facial whiteheads, dry skin patches, dry mouth, and feeling overly exhausted and irritable."

• She...
• Taken for 1 to 6 months
• March 24, 2021

"Started January 2021 for asthma. I spent most of 2020 on antibiotics for sinus infections and prednisone for asthma. Blood eosinophils were nearly nonexistent on blood tests, literally 0.1. Started off fine, after 4 doses, my blood pressure started going crazy. I was asleep 20 hours a day (no exaggeration). Two ER visits in 2 weeks and admission for BP 213/121. No one could figure out why BP was flaring to stroke levels repeatedly. A 24-hour BP cuff showed it was spiking even while I was asleep. We stopped Dupixent, and 2 weeks later my BP is finally settled, and I can make it a whole day without napping. Really sad as it was helping, I felt less wheezy, and my stuffy nose went away. Lucky to all those that it’s helping, me, I’m back to the drawing board."

• Dav...
• July 12, 2021

"Was diagnosed with AERD / Samter's Triad 10+ years ago and have had asthma, skin issues, and chronic rhinosinusitis that was near deadly several times (went into anaphylactic shock). Was on a cocktail of drugs previously including prednisone when I would get sinus infections every 3-4 months. Have been on Dupixent now for about 4 months, and it is literally life-altering. Have nothing but positive things to say about this drug, it has been wonderful for me. In response to another person posting above about her son using it, the actual needle isn't what causes pain of injections (unless you hit bone with the needle). The liquid being injected is what hurts, and that is normal. Make sure you allow the drug to warm up for 30-45 minutes before injecting as per instructions. Also, if you inject it slowly but steadily, it will lessen the pain."

• Anonymous
• January 1, 2021

"I have had severe asthma since infancy. The last several years, with frequent fires/smoke, I have had daily breathlessness and several ED visits with frequent steroid use for over one month at a time. I noticed after a few months of being on the medication, I can finally breathe better. My breathlessness has gone from daily to a few times per week and resolves with a rescue inhaler. This medication has greatly improved my quality of life over the past several months, and I am finally able to exercise again. I am not going off this medication until I complete my maintenance allergy shots, unless I begin to experience some other side effect that’s worse than not being able to breathe."

• Dri...
• May 9, 2020

"Someone asked, does the Dupixent shot hurt? I am deathly afraid of needles, and it is a very tiny prick. It will hurt going on if they administer it too fast. When I told the nurse, she backed off and administered it slower, and then it didn't bother me. I was just asking the nurse to slow it down. Btw, this was my first round with the 2 injections."

• Sic...
• Taken for 1 to 2 years
• July 19, 2022

"I started Dupixent in 2020 and thought everything was good until April of 2022. April 11, 2022, I called for my refill. I finally got it refilled, and it became the worst day of my life. Since then, I haven't gotten any refills because Dupixent refuses to pay Ingenio. I've gotten several $3349 bills, phone calls, emails, and texts. I've called all parties involved asking for management, NOTHING. Dupixent is telling me one thing while telling Ingenio something else. When I called Dupixent for the refill on 4/11, the rep from Ingenio said she wanted us on a recorded line so they would be liable in case something went wrong. I've asked for that recording and, of course, I have yet to get it. Dupixent and Ingenio are both horrible companies that don't help. I would not recommend this product for anyone. It put spots on my legs. My knees became so weak they would swell, and I couldn't walk. Don't use it for your safety."

• t2z...
• Taken for 1 to 6 months
• October 23, 2023

"Asthma - I am on my 4th injection after the loading dose and it is not working very well. My coughing attacks have reduced in severity but are still occurring. My breathing has not improved more than a trifle, and I am once again dependent upon my rescue inhaler a few times per day and especially at bedtime. I have had two severe and one very severe breathing attacks that have required me to use my Nebulizer to get my breathing back under control. I was switched to Dupixent from Tezspire and I am going to speak with my doctor about going back to the Tezspire since the time that I have been on Dupixent I have felt worse and it has barely touched my asthma symptoms."

• Ast...
• Taken for 2 to 5 years
• August 20, 2022

"I was diagnosed with asthma at 50 after years of wheezing and terrible sinus infections (sense of smell was completely gone) and being treated every month with prednisone, antibiotics, and Fasenra. Fasenra did not do anything despite being on it for over one year. I was not getting better. My asthma doctor and ENT thought the sinus infections were related to my asthma, so I had sinus surgery where they discovered and removed many polyps. Post sinus surgery, in about two months, I was right back to the same conditions as before. Finally, frustrated and without recourse, I was put on Dupixent, and about two weeks after the first dose (600 mg), my nose started to clear and I could breathe without wheezing, particularly at night. Now, two years later, I have had no more sinus infections, the polyps are gone, and I have not used an inhaler in over two years. Dupixent has worked incredibly well for me and is highly recommended if you’re at wit's end with sinus infections and asthma."

• Anonymous
• August 3, 2022

"Dupixent is working well for me. However, I was on vacation, and one of my syringes broke, so I called 10 different numbers to try and get a replacement, and nobody ever called me back. I rely on this drug to breathe, and I find it very disturbing that nobody ever called me back to follow up."

• Bel...
• Taken for 1 to 6 months
• June 12, 2022

"I almost died from my last asthma attack, I was rushed by ambulance to the hospital and put on a mask forcing air and put on oxygen and steroids again. This has happened several times each year and is getting worse. Literally overnight after injecting Dupixent, my oxygen saturation level has not decreased below 97. Amazing! Dupixent has saved my life."

• 2MT...
• Taken for 6 months to 1 year
• June 26, 2023

"I went on Dupixent seven months ago, 300 mg twice a month. It has worked wonders for my asthma and for nasal polyps. It pretty much cleared up both 100%. The problem is that I have developed hip pain in both hips. I am working with my doctor now to lower the dosage and hope that will help. I want to stay on the medicine, but I am worried about the hip pain."

• War...
• Taken for 1 to 6 months
• July 28, 2021

"I just took my second self-injected dose. So far, no problems. Virtually painless and no side effects. My doctor has taken me off the prednisone, and so far no exacerbations. Without prednisone, I was in the ER about once a month. I hope I never have to go back on prednisone. Bad side effects."

• Lin...
• Taken for 1 to 2 years
• May 16, 2024

"Experiencing weight gain. Also, I am experiencing some wheezing. This medicine is for my asthma. I also feel as though my bones are hurting. I did experience some asthma attacks. I do take a steroid medicine for my asthma. Can’t seem to stop the asthma medicine. Not sure if the Dupixent without steroids will ever be just taken."

• Dup...
• Taken for 5 to 10 years
• February 17, 2024

"Using for asthma, better asthma control, no more exercise-induced, no ER visits, better seasonal allergy control, fewer sinus infections, still can get breakthrough bronchitis or asthma requiring oral steroids, still using Symbicort, side effect is dry eyes, extra monitoring by eye doctor, steroid eye drops & replacement tears."

• Cat...
• Taken for 1 to 6 months
• July 3, 2022

"I have moderate, persistent asthma (steroid dependent). After trying nine, yes, nine maintenance inhalers and having a whole 2 months' worth of prednisone and countless trips to the ER this past year, my lung doctor finally gave me Dupixent. Within a month, I feel better but hoping it’ll improve even more! There are still triggers like cigarette smoke that set me off, but I can control it now. I take 2 puffs of an albuterol inhaler and I’m good to go. However, the only thing is I do notice that after taking it, about 10 days or so into the dose I’m on, I feel it wearing off! But it helps a lot! :) So glad I have this drug. So far, no side effects."

• Niz...
• Taken for 6 months to 1 year
• November 10, 2021

"I had zero smell due to nasal polyps and had 2 surgeries that temporarily relieved the pain/situation but never got my smell back. Started Dupixent Feb 2021 and have never had any side effects, and it has changed my life. I cannot imagine going back to the many medications I was on before I found this solution. I was on Claritin a day, Breo, Flonase, Astelin, plus prednisone frequently when I would have allergy or flare-ups. Now I only take this one medication and do not need anything else. A blessing in my life for sure."

• Jef...
• December 28, 2021

"I have had really bad asthma since I was a kid and mild COPD. I have been on Symbicort and Ventolin for many years, using my Ventolin as much as 10 times a day. I also had to use prednisone on a regular basis. I finally got put on Nucala a few years back, and it definitely helped, but would wear off before the next injection. My doctor switched me to Dupixent, and my asthma is way better. I've been on it for 12 weeks now. I suggest going on the 300 mg. It definitely works. All the best and happy breathing!"

• Har...
• Taken for 6 months to 1 year
• July 20, 2023

"I tried Fasenra first but had a slight allergic reaction to it, so they switched me to Dupixent and that seems to be working fine. I did have a few weeks where my breathing was great, then the pollen started and the smoke from Canada wildfires came along, but all in all I think it has helped with my breathing issues."

• Anonymous
• Taken for 6 months to 1 year
• May 11, 2022

"Dupixent saved my life. I went from being horribly sick for many years, not being able to breathe, living on and off of a breathing machine, inflammation in all mucus membranes, to being 80 percent healthy! The shot can hurt immensely but is worth it!! I have Aspirin Exacerbated Respiratory Disease."

• Bob...
• Taken for 2 to 5 years
• March 23, 2022

"Prior to taking Dupixent, I was on a low maintenance dose of prednisone, and on top of that, required a high dosage burst of prednisone from 2 to 5 times a year to stabilize my asthma symptoms, specifically severe cough and shortness of breath (low peak flow). I had nasal polyps that required two prior surgeries and a history of frequent sinus infections. After a brief period of taking Dupixent, I backed off the prednisone maintenance dose. For 2+ years, I have not needed to take any prednisone to manage my asthma symptoms. I still cough, but peak flow is perfect. No deterioration in nasal polyps and no significant sinus infections. I have had no noticeable side effects at all."

• JoJ...
• Taken for 2 to 5 years
• November 5, 2021

"In Sep 2009, I collapsed in a parking lot and was rushed to the ER. They found that my entire left lung was full of “tumors,” and removal of my lung was suggested. I refused and sought a proper diagnosis. Finally, in Nov 2010, I was diagnosed with allergic bronchopulmonary aspergillosis. I was started on antifungals, high-dose steroids (60 mg/day for a year), and underwent a series of 17 bronchoscopies over about 2 years. I still had exacerbations multiple times per year, often requiring hospitalization. I then was diagnosed with eosinophilic granulomatosis with polyangiitis. My pulmonologist/immunologist started me on Nucala until Dupixent was FDA approved for asthma. After my 3rd month on Dupixent, I was an entirely new person. I have completed 76 doses and have not needed another bronchoscopy. I have experienced severe eye sensitivity to light, which has improved over time. The injection does burn, but it pales in comparison to the lung pain I used to experience."

• Lyn...
• Taken for 1 to 6 months
• January 22, 2022

"I have had severe asthma since birth. For the last few years, I have developed remodeling of my lungs. Basically, my lungs are damaged, making it hard for me to breathe, like emphysema. Like others, I have to be on steroids a lot. I have tried a lot of meds and shots, nothing has worked. I've been on Dupixent for a month. Still having problems breathing. I have noticed increased heart rate, especially the first few days after the shot, skin problems, aching in my joints, fatigue, and now for 2 days my eye hurt, I can't see, poor vision, very red, oozing, and feels like pencils in my eyes. I really want to give it a chance and hope the symptoms will go away."

• Pat...
• Taken for 1 to 2 years
• September 12, 2023

"Dupixent has helped my asthma immensely. Prior to starting Dupixent, I needed steroids (Prednisone) almost monthly. Since starting Dupixent, I only needed steroids twice this year. I am also less short of breath. I had joint pain after the first two doses, but then none. I had injection site redness and bruising with the autoinjector. I switched to the syringe and had no reaction."