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User Reviews for Zenzedi

Zenzedi has an average rating of 8.3 out of 10 from a total of 28 ratings on Drugs.com. 78% of reviewers reported a positive experience, while 15% reported a negative experience.

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Zenzedi

ADHDMedGoRound · Taken for 5 to 10 years · November 9, 2021

For ADHD "I'm 37, was dx'd ADHD at 9. My parents thought it was rubbish due to my grades and voracious reading, and that my typical ADHD (and ASD) traits was me being lazy/immature/bratty/oversensitive. After two decades of life failure (grades don't predict success) I sought treatment. Only Zenzedi (NOT any of the generic d-amps) helped reliably with my inability to not procrastinate, interrupt, lose things, feel so overwhelmed that I avoided everything. Unfortunately, there is a shortage of this med and I've heard that it may be discontinued in favor of a new "non-abusable" IR d,l-amp product by the pharma corp that makes Zenzedi! And like many medical decisions made in this era, citizens have no ability to change the outcome."

10 / 10
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Doug · March 7, 2018

For ADHD "After years of adderall and the inconsistency in quality offered by generics, Zenzedi is the only medicine that has worked great for two years now. No hard crashes with mood swings. Effective for 4 to 6 hours depending on my food choices for the day. No insomnia problems as long as last dose is between 4 and 5 pm. I'm prescribed 30mg 3 times daily."

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ICouldSleepAllDay · Taken for 6 months to 1 year · January 13, 2019

For Narcolepsy "I have Narcolepsy without Cataplexy with extreme EDS and ADHD--the double whammy. Modafinil helped but not enough--very unpredictable-- and, of course, did nothing for the ADHD. Vyvanse gave me GI trouble and I still had sleep attacks plus a terrible "crash". Adderall was the worst, as it gave me a paradoxical effect: I was even more lethargic on Adderall, also irritable! I wasn't expecting much better when I tried Zenzedi but it has helped my narcolepsy greatly and also helps my ADHD with no side effects or crash like Vyvanse. Great medication, I just wish it was easier to find. CVS and Walgreen's couldn't even order it for me, said their wholesaler didn't carry it (???)."

10 / 10
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Faike · Taken for 5 to 10 years · September 9, 2020

For ADHD "Zenzedi is my favorite ADHD medication by far little side effects lasts a long time no strange tolerance build up either, I take it in the morning and it works 100x better than Mydaysis, Adderall brand or not, the weird chewable one, and Vyvanse. I've been on all of them I think and I really find this one to be the best. My insurance doesn't cover it but I don't care it's worth it - I rather spend money on one drug that helps rather then a bunch of other adhd medications combined."

10 / 10
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Louis Cyphre · September 10, 2020

For ADHD "Generic Adderall started to do nothing but cause me anxiety. Generic dextroamphetamine tablets are now about 30% as effective as Dexedrine and Dextrostat tablets were. Both have been discontinued. Vyvanse is effective, but sometimes I do not want or need something that lasts 12 hours, and other times, it wears off after 8-9 hours and I need a booster. This works as well as original Dexedrine tablets. There is no lactose or gluten, unlike the garbage generics. Truly an amazing med for my ADHD and fibromyalgia/chronic fatigue."

10 / 10
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Megsadd · Taken for 1 to 6 months · January 19, 2017

For ADHD "I wrote previously about loving Zenzedi and switching to Adderall XR due to insurance. After 1 month of Adderall, I am going back to Zenzedi. Adderall was just not for me. I had mental issues all month long and just didn't focus as much. My family even noticed a difference. I called my Insurance and they approved Zenzedi easily."

10 / 10
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SilasSilasSilas · Taken for 1 to 2 years · October 18, 2014

For ADHD "I take two 20mg a day (one in the morning and one in the afternoon). Details: -20 y/o female -diagnosed ADD for 4 years -tried Adderall (worked decently, bad crashes) and methylphenidate (nausea, motion sickness, didn't help ADD) -other conditions: severe depression, OCD PROS: -extremely helpful, like night and day -no jitter, tremor, etc -no crash CONS: -reduced appetite -*have to special order through Target pharmacy because most places don't keep it in stock"

9 / 10
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Dextro, Dexy · Taken for 1 to 2 years · March 19, 2015

For ADHD "The most reliable and consistent ADHD CNS I've ever taken! Their new instant release tablets they came out with recently, are really great. Instead of taking the usual four salts (Adderall), you have one (Dextroamphetamine Sulfate). My grades and focus went up about 30 percent after taking these on right dose. I've been stuggling with ADHD since I was 6 yro. Also, I take 30mg x 3 per day. I always joke with friends that dexy makes me feel sexy."

10 / 10
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Narcolepsygirl · Taken for 2 to 5 years · August 8, 2021

For Narcolepsy "I’ve tried sooooo many medications for my narcolepsy with cataplexy and extreme EDS! Nuvigil and Provigil do not work for me. Focalin made me extremely angry and anxious. Ritalin just quit working. Vyvanse did nothing. Sunosi did even less. Adderall worked great but I have a wheat intolerance and the generic I was using caused a major flare up for me. And the list could continue… I discovered Zenzedi and asked my sleep doc about it. She hadn’t heard of it but we gave it a try. After almost two years, I’ve only had to increase my dose once (from 20mg twice daily to 25mg twice daily). This stuff is magical for me. It keeps me awake with very few side effects and no crash. I take my doses about 5-6 hours apart. I’ve always been a runner but this medication and a pandemic have allowed me to run virtually everyday which I believe also helps my EDS. I cannot take the generic version."

9 / 10
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Anonymous · Taken for 1 to 6 months · August 4, 2021

For ADHD "Been prescribed this for 6 months now 15 mg twice a day needed to boost me up to 30 mg twice a day but no side effects feel great my local cvs now has it all the time for me. My insurance covers it I pay ten bucks for 60 and have gotten off all my bi polar meds and depression meds due to this med love it"

10 / 10
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Condell · July 26, 2016

For ADHD "The generic for this med didn't work at all, however the name brand (for some reason) is amazing! It has changed my life after so many other meds have failed. I am able to study, take notes, and remember what I've read now. The only reason I did not give it a 10 is because I am having some issues with insomnia. I'm sure that is related to the timing and strength of my last dose of the day however, and will adjusted. It can be expensive, however after trying everything else and nothing else working, I would rather pay for this than deal with awful symptoms all day."

9 / 10
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Megsadd · Taken for 6 months to 1 year · December 19, 2016

For ADHD "I was on zenzedi for about 6 months. I loved it! I have only tried Ritalin for my ADD and it made me psychotic, and once I stopped taking it I was too scared to take anything else. Well 10 years later, and sick of my ADD, I was prescribed this medication and it worked! I also had no beginning side effects. The only complaint I have is how quickly it wore off, but it could be my own metabolism and anyone else could be different. However, due to my new insurance I am switching to Adderall XR, I'll write an comparison opinion when I begin taking it."

10 / 10
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Anonymous · Taken for 1 to 2 years · December 12, 2021

For ADHD "This medication has helped me tremendously and Is night and day from generic Adderall in effectiveness for me. My two complaints would be recently in Dec 2021 I've had trouble with my Zenzedi 30 mg getting to the pharmacy due to a backorder. It has interfered with my treatment and didn't realize how effective this medicine was until I went back to generic adderall. It has been a very underwhelming change to say the least and on top of it my doctor wrote the prescription for same mg of generic adderall as I was on for Zenzedi and can say anyone that has experienced this knows they are not near equivelant per mg. Second complaint- I recently was laid off from work and lost my insurance that had me at a $30 copay for my medicine. Well no problem I remember the savings card through Arbor Pharma said cash paying patients pay no more than $75, well how dishonest that was. Cheapest I've been able to pay was using a Goodrx for $230 each fill. Not a pleasant experience paying that much!"

7 / 10
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The absolute best · Taken for 1 to 6 months · April 11, 2016

For ADHD "Have gone from Adderall to Vyvanse to Dextroamphetamine IR and after 6 months on this, I can say it is by far the best. Same cost as the generic for the same quantity with my insurance and I like the higher dosages since I take 40mg/day. It has the consistency of Vyvanse with the duration of IR tablets."

10 / 10
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aus · Taken for 1 to 6 months · December 31, 2020

For ADHD "I had been taking Vyvanse close to a year with great success, but needed something I could gauge when I needed to dose and not take Vyvanse which kept me awake for 12-13 hours. Switched to Dexedrine and went through 3 months worth (all different manufacturers) of horrible generics. I finally got Zenzedi this last month, and it seems to work for maybe 45 minutes. This is not what I was expecting, did the formula change or something? It feels like I took a bad adderall to be honest. Generic Sandoz adderall is more like vyvanse than Zenzedi is, at least for me lately. 10mg 2x a day. Has anyone else noticed an issue lately?"

3 / 10
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Evilmage · Taken for 1 to 6 months · October 9, 2018

For ADHD "This stuff makes you feel like the king of the world! Unfortunately, that euphoria after 5 hours turns to dysphoria and the crying starts. Horrible thoughts that I'm a failure and no way to calm down. There should be an extended version of this drug because that 5 hour comedown is horrible."

2 / 10
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Prius · Taken for less than 1 month · February 15, 2021

For ADHD "It works well, strong enough at 20mg, only lasts as long Adderall. Needs to be redosed later on in the day. I feel that it has more focusing power than Dexedrine spaniels 15, Ritalin ir 20, or adderall ir 20, however I notice some serious clenched jaw and an urge to grind teeth even into the next day while not taking it. It’s strong and effective, however I would also like to mention, the feeling of withdrawal from 1 day of this medication reminds me of the withdrawal of months on adderall. It’s definitely a great medication, and I remember thinking it has fewer side effects and greater consistency than generics. I would also like to add I’ve been diagnosed ADHD since I was 7, and have been on most every ADHD medication and even with record of this my insurance continues to deny covering this medication, even after countless phone calls."

9 / 10
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RanthonyD · August 1, 2021

For ADHD "I have ADHD, formerly known as ADD. It wasn’t caught until I was about 19 years old, around the same time my mom was diagnosed with it as well. Turns out that it is usually hereditary, and is related to Neuro degenerative conditions and can actually progress into things like fibromyalgia, multiple sclerosis, Parkinson’s and even Alzheimer’s. I have fibromyalgia/chronic fatigue syndrome, narcolepsy, suspected multiple sclerosis but insurance won’t pay for the test, and even now getting symptoms of Parkinson’s. There are only four ingredients in this formulation. They are also free of lactose and gluten, with no generic company will guarantee. I am lactose intolerant and celiac, so the generic medications would make me very sick. These have far fewer side effects and are almost as good as the original dexedrine tablets. I can’t put my finger on what exactly is missing, but they are very very close to being as effective."

9 / 10
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Elbarto150 · Taken for 1 to 6 months · April 10, 2022

For ADHD "Over the past 10 years I have been on a variety of different medications to help treat my ADHD. These include Adderall (which was my go-to until recently), Vyvanse, Ritalin, Focalin and Adzenys. I never loved any of them but out of that list I found Adderall the most tolerable. Recently I read online about Zenzedi and asked my doctor if I could try it. It was a bit of a hassle to find a pharmacy that carried it, but I eventually got a supply for a month. I am so glad I did. This is by far the most effective and side effect free of any / all of the ADHD medicines I have tried. It gives me the focus and motivation headspace that Adderall provides without the amped up, heart pacing feeling that makes me uncomfortable and anxious. Also, unlike Vyvanse it doesn’t last forever so I have better control over how to time my 2 doses during the day. Overall, an excellent medication!"

10 / 10
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5chicks · Taken for less than 1 month · June 13, 2016

For ADHD "I would rather not take any medicine at all than take this med. it made me feel awful. Achy all over, headache, blurred vision, no energy. Numbness in hands and feet. I wouldn't recommend it. It didn't help me focus or stay awake. In fact I just wanted to lay down it made my head hurt so bad."

1 / 10
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Radicaldelusion · Taken for 1 to 2 years · August 4, 2022

For ADHD "This was far superior to generic. Gluten-free. No anxiety, no crash, provides me with flexibility with time of dosage. Not quite as effective as the old Dexedrine instant release tablets, but very close. No side effects other than slight dry mouth."

9 / 10
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Anonymous · Taken for 1 to 6 months · September 13, 2022

For ADHD "I had been on brand name Dexedrine tablets for over 10 years when I lived in Canada. It is reliable and predictable, and I always noticed the effect soon after. Upon coming to the US I have been prescribed Zenzedi and it just isn't the same. It seems like it takes about an hour longer to notice, and it feels less energizing than real Dexedrine. To compensate for the lack of effect I have increased dosage which seems to affect me at different times in different ways. It's tough to figure out I am just seeking consistency. Another thing that stands out is that the tablets feel like they are cheaply made. It's tough to split them apart because they're too compact, yet they immediately start dissolving in the mouth unlike regular tablets. Very different, and IMO, less effective than the OG Dexedrine."

3 / 10
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Focus 2 · December 12, 2022

For ADHD "For ADHD a timer really helps. 10 minutes applied efforts towards study. 3 minutes of something entirely different. In education, classes change on the hour and so should the subject material. Math problems, (starting simple), then maybe Art Crossword, Architecture, Photography. Music; playing an instrument or editing. Memorizing a new phrase in Mandarin or German This enables different parts of the brain to integrate."

10 / 10
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Nate · Taken for 6 months to 1 year · January 5, 2019

For ADHD "I’ve taken stimulant medication for 13 years. I’ve found Zenzedi superior to Adderall, Vyvanse, Straterra, and Ritalin."

10 / 10
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Amazing · October 30, 2022

For ADHD "This drug is the only ADHD medication that worked for me."

10 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.