Clomipramine for Obsessive Compulsive Disorder User Reviews (Page 3)

• Tay...
• November 16, 2015

Clomipramine "This medication was a miracle for my OCD, like, I swear my intrusive thoughts had almost gone! I was able to do things that I couldn't do with OCD! Sadly, I couldn't continue it as I got a really bad side effect of low blood pressure! I wasn't able to do much during this time. It was worth a try though!"

• Anonymous
• Taken for 1 to 6 months
• May 17, 2018

Clomipramine "I have been depressed for years and just recently discovered I had OCD. Only 1 or 2 medications would help, and then they would stop. I tried holistic supplements and diet, and nothing helped. I was becoming hopeless, and then I heard about someone who tried Anafranil. I started on 25 mg and gradually went to 150 mg. Finally, after 4 or 5 weeks, I started feeling better. I wanted to get up and go to work in the morning. Side effects were a dry mouth, insomnia, and some dizziness, but I'm hoping they will go away with time. I would recommend it."

• Anonymous
• December 5, 2009

Clomipramine "My son is 14 and has suffered with OCD for 2 years. Lexapro made him a happier obsessive with extreme gas but OCD symptoms no better. Anafranil has been great. Has fewer obsessions with less anxiety. It's an older drug you have to ask for."

• Sar...
• Taken for 5 to 10 years
• January 9, 2018

Clomipramine "I was diagnosed with OCD when I was 18/19, but I'd had intrusive thoughts from as early as I can remember. It just got worse to the point I was suicidal in my late teens. Anyway, luckily, the psychiatrist I saw was able to diagnose me and prescribe me Anafranil. I can honestly say I probably owe my life to this medication. I took it for a number of years before switching to sertraline. I find Anafranil does make me drowsy, but the effectiveness of it is worth it at times. Not everyone can take SSRIs. I'd recommend trying this medication for OCD or other anxiety disorders. :) Peace."

• Anonymous
• October 21, 2010

Clomipramine "Anafranil saved my life. The side effects are not pleasant, but not having the intrusive thoughts is well worth the effort! I am scared of long-term effects, but my fears are lessened by the effectiveness of Anafranil for OCD."

• the...
• Taken for less than 1 month
• July 17, 2020

"Worked right off the bat. Just 25 mg at night worked way better than any antipsychotic I've tried (SSRIs barely helped at all). My mind has finally quieted down. It's a blissful feeling altogether. Definitely give this a shot."

• Hab...
• Taken for 6 months to 1 year
• January 16, 2025

"I’ve been struggling my whole life and had no relief until my early thirties when my current psychiatrist gave me no option but started taking clomipramine. Currently on 150 mg, and it feels awesome, no major issues with side effects. Highly suggest taking it along with CBD oil drops. Trust me, I’ve tried at least five different antidepressants, antipsychotics, mood stabilizers, and sedatives, among others. When I look back, I feel sorry for myself for not stepping up and asking for those two drugs. Now I’ve got a career, a steady job, and I live by myself. My thoughts, behaviors, everything was compromised until now. I truly believe that it is not psychological but biological. Give it a try, you must be miserable at the moment anyway."

• Cha...
• Taken for 1 to 6 months
• April 6, 2020

"Out of all the medicines I have tried for my anxiety/OCD, this one, clomipramine, has worked the best! I take 50 mg a day, and it took about 3-4 weeks to start noticing a difference. I went from OCD thoughts running my life all day/every day to having small thoughts throughout the day that I am able to easily dismiss. My panic attacks are also gone! Side effects have been dry mouth, a little bit of weight gain (maybe 5 pounds), and sexual side effects (delayed ejaculation). This medicine is expensive and has caused a few side effects, BUT IT IS WORTH IT!"

• pcw...
• Taken for 5 to 10 years
• June 25, 2016

Clomipramine "I was on Anafranil many years ago. Took it for 5 years. Unfortunately, after 5 years, it stopped working for me. But it is a wonderful medication. Give it a try. More than likely, it will work for you. If not, give fluvoxamine a try. It is another really good one. Only side effect was dry mouth. Small price to pay for the wonderful effects I got from Anafranil. Give it a try. When I took it, there was no co-pay. Nowadays, there probably will be a co-pay, but probably not a bad one."

• JDa...
• Taken for 1 to 6 months
• July 29, 2021

Clomipramine "I’ve taken Anafranil for a month now because I had been struggling with anxiety with an OCD element as well. I’m on 150 mg right now. This medication is definitely helping. I take Prozac 20 mg as well, and I think they work better together. For me, it’s helped to stop worrying and thinking about things that don’t matter. Also, I’ve had random intrusive thoughts of uncomfortable words popping into my head. It’s made me realize how ridiculous it really is and that it’s really a bad serotonin imbalance. My mood has improved as well, so I think this drug should be used more because it’s a potent drug. It’s gonna hit the anxiety/OCD hard, whereas I tried Zoloft, Viibryd, Pristiq, etc., and they alone usually aren’t enough. You gotta be on Anafranil plus Prozac/Luvox/Paxil or some other SSRI. I’m also on Rexulti, which basically boosts the two primary medications. No side effects so far either. Hope this is helpful."

• Rac...
• Taken for 1 to 6 months
• February 13, 2022

"This medication takes time to work. You need to be patient and give it maybe 3 months. Maybe more. It's given me my life back. From waking every day in terror, I now just wake up like a person without OCD. No SSRI drug has helped me. Clomipramine has removed the mild depression that I had for 2 years following an episode of clinical depression. It has taken away my constant anxiety and calmed my obsessions. I'll stay on it forever."

• Kal...
• Taken for 10 years or more
• December 22, 2019

"Been on clomipramine for most of my adult life. OCD took over my childhood, but now I'm free to be the person I am due to this drug. No major side effects, bad teeth in later life. No price to pay! Would recommend at an instant."

• Ste...
• Taken for 6 months to 1 year
• August 20, 2020

Clomipramine "Bear in mind that this, like any medication, may work differently for you, but I can attest to the point that it does not work for everyone. I had a combination of OCD and depression. I took Anafranil for months. For one thing, it didn't do squat for the condition. It didn't help one bit. What it did was make me so tired and lethargic that I could not do a thing. I failed a college semester because I simply could not keep myself awake, and there was not enough caffeine on earth to do it. It made my situation many times worse."

• hea...
• November 17, 2010

Clomipramine "Works well for OCD, wonderful for body pain, and moderate for depression (it takes 6-8 weeks for me to see any effect), but the side effects are not pleasant: dry mouth, fatigue, drowsiness, difficulty concentrating, and anorgasmia."

• per...
• September 24, 2019

"I first started suffering with OCD (intrusive bad thoughts) in my early twenties. I continued without seeking help but eventually, I was seen by a psychiatrist. The drugs prescribed were of no use, and I continued in pain and anxiety for many years, suffering the most horrendous headaches. At the age of 41, I again sought help. The new, brilliant, young female psychiatrist put me on clomipramine. I cannot thank her enough. I am now 73, still taking 25 mg clomipramine daily, if I can find them. Every 28 days, before asking for a repeat prescription, I have to call numerous pharmacies to see if they have any in stock. Sometimes, very rarely, I find 25 mg clomipramine tablets, but mostly 10 mg. I have a supply of 70 x 10 mg tablets for 28 days, taking 20 one day and 30 the next and so on. I cannot recommend clomipramine highly enough, it has been my lifesaver."

• UK ...
• Taken for 2 to 5 years
• December 9, 2016

Clomipramine "I have severe early onset OCD. I have found that clomipramine (Anafranil) has taken the edge off of it. I've been taking it for 4.5 years, SLOWLY building up to 200 mg, but have found that the side effects of this medication to be too much, in particular the excessive sweating. I am regularly dripping with sweat to the point I have been asked if it is raining outside because I'm soaked. I'm thinking of coming off of it because the sweating is exacerbating the OCD as I now have obsessions about it, and I'm constantly worried about people looking at me because I'm sweating so much, which isn't very feminine. I've tried to come off of it a few times, but every time I do, my OCD regresses into overdrive-highlighting how effective it is for OCD."

• Cal...
• April 13, 2009

Clomipramine "From reading the medical literature, this is probably the most effective treatment for obsessive-compulsive disorder, but the side effects led me to change. After a year of use, I switched to a less taxing medication. The weight gain was too much, and it made me more confrontational with others. However, for bringing my initial problem down to a manageable level before switching, Anafranil was a lifesaver."

• BeF...
• Taken for 1 to 6 months
• August 8, 2020

Clomipramine "I took Anafranil for 5 months at a dose of 25 mgs. Definitely took some power away from the intrusive thoughts, but not fully. Had a hard time with being tired in the morning, terrible dreams, mild constipation. On a positive note, I did not gain any weight and was able to work out regularly. Tried to go up to 50 mg, but that got rid of my libido. Felt like taking an upper and downer at the same time. Some of the time, I felt good, other times, I felt depressed. Unfortunately, couldn’t tolerate a higher dose. But if you really need to shut off the noise, this may be the way to go. Best of luck."

• Sha...
• August 31, 2017

Clomipramine "I was on Effexor for 3 months, and I really liked it besides the fact it didn't help with my obsessive/intrusive thoughts. I did quite a bit of research on medications and decided to ask my doctor if I could try Anafranil. I have been on Anafranil for a month now, and it has really helped with the obsessing over intrusive, meaningless thoughts. In the beginning, it did spike my anxiety, which I used a benzodiazepine to help with until the anxiety calmed down. After that, I noticed I started to feel dizzy when I stood up fast, and it was another side effect. At this point, I began to get nervous, but I heard so many good reviews about this drug I really wanted it to work. After making it through my first month with it, the side effects began to lessen."

• Ste...
• Taken for 1 to 6 months
• March 21, 2023

"This medication saved my life. I was dealing with intrusive thoughts every moment of my waking day, as well as horrible nightmares. From the first dose, I got some relief, and now the thoughts are gone entirely. It made me groggy at first and led to some insomnia, but it's gotten better. Sexual dysfunction, though, but having my mind back is the most important thing to me."

• Sam...
• Taken for 6 months to 1 year
• March 19, 2021

Clomipramine "Anafranil helped my OCD symptoms a little bit and helped me sleep at night. However, as my doctor increased my dosage, I started gaining weight, having horrible acne, and severe constipation. It also made me crave junk food like some kind of addict. I was on Anafranil for about 10 months and gained 40 lbs. I haven't taken Anafranil in about 8 months. I've lost the 40 lbs. I didn't have to go on a diet or anything, as soon as I was off the drug, my appetite went back to normal. However, 8 months later, and my colon is still not healthy. I still have major issues with constipation and bloating. My doctor had me try Zyliss, a drug for IBS, and it helps a little. I feel like Anafranil may have ruined my gut. I have a hard time leaving the house because I am so uncomfortable in my gut. I wish I had never taken this drug. I was much better off before."

• Ema...
• Taken for 1 to 2 years
• March 27, 2019

"This drug has completely changed my life. I’m now 28 and have been suffering with OCD since I was a young child. I wasn’t prescribed anything until I was 18 and shifted through medications until I had a complete breakdown at 26. I was prescribed clomipramine by a psychiatrist for my OCD, and while it took many weeks to take full effect, I’m so thankful I stuck out the process. The side effects at first were not so nice, but looking back, it was NOTHING in comparison to the mental anguish of OCD. I highly recommend giving clomipramine a try if you’ve been prescribed it for OCD. I obviously still have occasional intrusive thoughts, but they are much, much easier to brush off now. I actually go through my day with maybe only five compulsions as opposed to the hundreds (not joking) I used to have."

• Lua...
• Taken for 1 to 6 months
• January 18, 2013

Clomipramine "This drug was a miracle for me! My problem was that I was always late for any and every little thing I attempted to do, and it was ruining my life. It is very baffling for me because I started with only 25 mg, and within four days, I was automatically, not just on time, but early for everything, without any thought or effort! I was ecstatic. This phase lasted 3 weeks. The doc said I'd be a superwoman when she amped me up to 50 mg. Well, that made it stop working! I began to slowly regress, and then started to be extremely drowsy to the point of even falling asleep at the wheel -- and worse, it wasn't even working! We experimented with it, but it never worked again, and I am super sad about that."

• Phi...
• Taken for less than 1 month
• January 5, 2023

Clomipramine "So far, I have been on 25 mg for about 2 weeks. It has given me much more headspace than other antidepressants I've tried so far. Sometimes I can now redirect my attention and not fixate on the thoughts. Obsessive thoughts do still come, though, but I need to put in the work in ERP anyways. I am having good hopes for increasing the dose now. The only issue is it makes me really constipated right now. But compared to every other antidepressant, I believe this is one of the best for OCD."

• Inf...
• Taken for 1 to 6 months
• July 30, 2022

Clomipramine "My experience with Anafranil over the past 3 months is as follows: severely chronic constipation, urinary retention that hospitalized me the other day, a 60 percent increase in my depression, a 90 percent increase in my overall anxiety, and at best a 15 percent decrease in my OCD symptoms. Not to mention the sexual dysfunction that includes painful orgasms and low libido, and then there's the constant dry mouth. I cannot for the life of me recommend this medication to anyone. I'm currently 5 days away from discontinuing this medication and replacing it with Prozac."