Wellbutrin for Depression User Reviews (Page 3)

• Fai...
• Taken for less than 1 month
• November 27, 2021

"I am on week 3 on Bupropion 150 SR, I went off Paroxetine cold turkey and started this. First week, I was tired all the time and had some weird nightmares that went away starting the 2nd week. Then the 2nd week, I felt awkward. I was not myself, I was very irritable, didn't want to be around people, had some headaches that week, and wasn't interested in doing many things. I was about to quit, but my doctor told me to please give it a try until week three when it is supposed to start working (from week 3 to 6). So I did with a lot of effort, and I am so HAPPY I DID HANG IN THERE!! I FEEL SO MUCH BETTER. Today is my day 22, and I at last feel peace, joy, and motivation again to do things I didn't want to do before. I am eating less, not so hungry, stopped smoking, and do not need caffeine to function as I did before. It doesn't have side effects on libido like Paroxetine. So far, it has been worth the wait of 3 weeks of not feeling so well. IT IS WORTH IT. PLEASE HANG IN THERE!! Pray for all to feel happy."

• AAn...
• November 13, 2014

"I was on Prozac and felt tired all the time, still depressed, and no sex drive. I thought maybe the dose wasn't enough and I was going through menopause, but the doc put me on Wellbutrin. I'm with the person above, I cannot believe in one day I felt better. I thought it was in my head. I made phone calls I would avoid because of anxiety, I got things done instead of sleep, and I felt so much happier next to my husband. Day two I woke up ready to start the day, completely the opposite of what I had been experiencing. Everyone is different, and you just have to see what works for you. Prozac is in a different class, and I just needed this antidepressant."

• Mia...
• August 7, 2013

"I am a 25-year-old woman and started taking this 6 days ago along with clonazepam for anxiety. 300 mg of Bupropion once a day (mornings) and clonazepam twice a day (once in the morning and once in the evening). I have to say that... so far THIS ROCKS. I was suffering from depression, obsessive thoughts, anxiety, and panic attacks for months. I stopped taking Zoloft after a year because I gained 60 lbs on it. Now with Wellbutrin, I have no side effects except loss of appetite and more energy. I feel more energetic, happy (almost 'giddy') and hopeful for the future. My anxiety and depression were debilitating, and this saved my life. I can't wait till the full effects kick in. 6 days in and I feel the difference."

• Kat...
• Taken for less than 1 month
• July 20, 2014

"I am on Day 3 and I am starting to notice some if not all of the effects. My mood is stabilizing and I am finding my motivation returning to me. I need it for when I get into my doctoral program! I can find pleasure in things I enjoy again. I don't have overtly pessimistic and sad thoughts as much. I'm not crying as much. Before I started taking this medicine, I was not at rock bottom, but I did not want to feel awful anymore. Depression is a real disease. The medications do help."

• neb...
• Taken for 6 months to 1 year
• February 7, 2014

"I was diagnosed with major depressive disorder a few years ago. I've tried basically all SSRI antidepressants. They did nothing for me other than make sex impossible, gave me leg tremors, as well as massive weight gain. I switched to Wellbutrin, and my sex drive is back to normal, my weight is dropping, and I feel a lot better. I recommend this medicine to anyone struggling with SSRIs and their many side effects."

• jaf...
• April 1, 2013

"I'm a 19-year-old college female. I was struggling with anxiety and depression for about six months and went on Zoloft in December 2012. It made me even more depressed, even though it helped with the anxiety. Zoloft also made me a zombie (napping for hours during the day, no motivation to socialize, no motivation to do schoolwork, nothing). I went off it about a month ago and switched to 150mg of Wellbutrin daily. I noticed a difference the FIRST day. It gave me the energy/positivity I have been lacking for months, and I finally am starting to feel like myself again. I recommend it to anyone who Zoloft didn't work for or who needs that extra boost to come out of a fog."

• But...
• Taken for 1 to 2 years
• October 22, 2013

"Bupropion has been the best ad for my very difficult-to-treat atypical depression. I gradually felt improvement as my doctor increased my dosage over the course of the year. It was helping a little when I first started at 150 mg, but I felt it could do far more. It's been amazing at 450 mg, my current dose. I'm level-headed, focused, and not at all exhausted. I was so tired and wanted to sleep. It also helps me with my addiction to food as I've been captive to this my entire life. I'm slowly losing weight because I'm walking a lot more and not binging. I sleep great too, and I do not feel agitated or nervous. I don't want to consume alcohol like I used to either! It's a total different ball game than the SSRIs I've tried! I'm grateful :-)"

• Car...
• Taken for 1 to 6 months
• April 19, 2017

"I have been taking 150 mg of the generic of Wellbutrin for the past month. I can't believe how amazing I feel! After dealing with depression for the past 4-5 years, I finally feel like myself again. I was diagnosed with PMDD and mild depression but tried to deal with both of these with Prozac and hormone birth control. After three months of Prozac, I quit. It made me tired and took away my libido. It didn't help my depression at all. I've tried three different birth controls (I'm 46... it wasn't for birth control, just to try to help my hormone levels.) Nothing helped my depression. Finally, my doctor prescribed Wellbutrin. I filled it but didn't take it for 8 months because I was afraid of the side effects. Now I could just kick myself!"

• c3l...
• May 16, 2013

"This medicine really works for me and has really improved my quality of life and perspective on things. I'm 18, and I have been on this for a little over 6 months, and I would say the only bad side effect is dry mouth, but if you just drink a lot of water, you'll be fine. I like it because it has helped me stop 'binge' eating. I don't have cravings for food or cigarettes anymore, and I completely stopped smoking. I'm never tired anymore, Wellbutrin definitely gives you energy in a good way. Sex drive is completely normal, and I still have normal emotions, unlike when I was on Celexa or Prozac where I felt so emotionless. I lost 20 lbs, but I am healthy and fit and a lot happier with myself."

• Anonymous
• March 18, 2010

"I have been taking Wellbutrin continuously for 20 years. If it were not for this miracle drug, I would be dead. There is no doubt in my mind that my intractable depression was arrested with Wellbutrin. I have a chemical imbalance that is permanent. I once went off Wellbutrin for a month because I was taking another medicine. Within three weeks, I was having suicidal ideas. Needless to say, I will not go off it again. My doctor assures me it is safe for lifelong use."

• Mea...
• Taken for less than 1 month
• September 24, 2018

"Have been on Wellbutrin SR 150 twice daily. BEST CHOICE I MADE!! I am a person that thrives off of happiness, feeling great, making others happy, etc! After one week, I am me again!!! HAPPY, SECURE, JUST ME!! I noticed it has helped chill me out. For those who don’t find this medication to work, maybe it is the wrong drug for your chemical imbalance. It is just a matter of finding the right drug for the right person. I'm thankful"

• Ron...
• Taken for less than 1 month
• March 12, 2025

"This medication was very hard to use, there was stomach pain and acid reflux. Sleep was poor, and I couldn't sleep more than 2 hours without waking at night. I became very agitated with anxiety and sadness that would come and go very fast. The agitation became worse, and I was looking for anything that irritated me to lash out and went into a rage and confronted others. My heart was always around 100 beats when I was at rest. I also had very strange thoughts that worried me I was losing control of my thoughts."

• Aug...
• Taken for 1 to 6 months
• January 13, 2020

"Having fallen into a serious depression which led me to have great difficulty in doing everyday things, getting up in the morning, brushing my teeth, washing, and also couldn't get important sleep. It was getting really difficult. My neurologist prescribed Wellbutrin XR 150mg once a day in the morning. I was very hesitant to take the drug for fear of the side effects. Today, after 3 months of treatment, I sincerely thank her. I have found energy, reconnected with my social relationships, etc. In terms of side effects for me, it's mild: dry mouth, a few palpitations often at night, and slight weight loss. In 3 months of treatment, I lost 4 pounds."

• sam...
• Taken for less than 1 month
• June 8, 2023

"I took two doses of 150 XL bupropion, on the second dose, I have immediate ear ringing, fullness, and pressure in my ears. I’ve never once had an issue with my ears in my life. I’m very young and healthy. Months later and after multiple ENTs, I have permanent tinnitus from this drug. It shouldn’t be legal."

• Jan...
• March 7, 2020

"DO NOT TAKE THIS IF YOUR PRIMARY ISSUE IS ANXIETY. I got on this medication because I was having trouble with anxiety and insomnia. My NP wanted to start me on Wellbutrin 150mg XL and I kept reiterating to her that I have no depression whatsoever, I’m just anxious, but she said it would help. Within 2 weeks, I was so nauseated, in a complete brain fog, my anxiety got so much worse, my heart would race, I was having panic attacks daily, couldn’t sleep, my mind was racing non-stop, and although I’ve never felt as if I had issues with depression, I was so depressed on this medication! I went from being very high-functioning with mild to moderate anxiety to completely useless on this medication. I called into work multiple times (which I had never done before - I’m a nurse). I couldn’t focus, was so disoriented, and felt like I was just floating. I stopped and feel much better after a few days and I got on a PRN benzo for anxiety."

• tha...
• Taken for 1 to 2 years
• October 21, 2018

"I have been taking Celexa for a while to treat depression, and while helpful, it had made me very numb, and I was still feeling occasional episodes of mild depression. My provider added Wellbutrin, and what a difference! Wellbutrin gave me a boost of mental energy and feelings of well-being that I had never felt before. I am currently doing very well with the combination of Celexa and Wellbutrin. I feel better than I ever have in my life. I've been on this fantastic combination for a year. Highly recommend."

• Ano...
• July 18, 2013

"I just took the first 100mg pill a few hours ago and I feel different. I feel almost normal. I'm not thinking about being depressed, and my energy is almost back to normal. No antidepressant, antipsychotic, or mood stabilizer has ever done that! If this feeling keeps up or gets better, I don't know what I'll do. I'll probably cry tears of joy. Is this what normal people feel like?"

• Ska...
• July 19, 2015

"Y'all! I am one of these people who cannot say enough about bupropion! It has changed my life after only day 8. Such a subtle but powerful shift in perception and decrease in troublesome habits (smoking one of them, but also irrational anxiety getting on train, rushing down the street for no reason, rushing through dinner) has decreased by drinking, made me feel less weighed down. There are side effects the first few days, but they will go away! Stick with it, and you won't regret it."

• Lan...
• Taken for 1 to 6 months
• May 25, 2019

"The heightened sex drive Wellbutrin (bupropion) is so powerful that I'm even having awesome sexual dreams in my sleep. It hasn't helped me to stop smoking, but I smoke very little to begin with, so maybe that's why I don't notice a difference. It totally smoothed out my mean mood swings. I just love it. I have zero bad side effects. I do believe the medication helps females' libido more than it helps most males, but I could be wrong."

• Sam...
• Taken for less than 1 month
• October 31, 2015

"I'm in my early 40s and have noticed the last couple of years I've become very agitated over nothing! Always yelling at my teenager and I could literally feel my blood pressure raising over the smallest things. Also this last year for some reason I became depressed. I didn't ever want to get out of bed or leave the house to do anything. I've always had a bad opinion about antidepressants, but I knew SOMETHING had to change. I reached out to my doctor who gave me 100 mg of generic Wellbutrin, and the very first day I noticed I was calmer! I fell asleep 2 hours later but woke up refreshed. I just finished day 3, and I swear I feel fantastic! Not only have I not yelled even once, I don't feel angry at all! And I want to do stuff again. Very happy"

• jud...
• Taken for 1 to 6 months
• June 11, 2022

"I've had moderate depression and some anxiety most of my life. It manifests mostly in the forms of low energy, worrying, irritability, and avoidance. Dishes piling up, laundry not getting done, car interior a mess, etc. I tried two SSRIs (Lexapro & Zoloft) before switching to Wellbutrin, which is a dopamine reuptake inhibitor. Dopamine! That was the answer. It wasn't a serotonin problem, it was a dopamine one! The SSRIs worked okay, but I was always tired and foggy. I gave each 6 months. I eased off the SSRIs and eased into the Wellbutrin. I only take 150 mg at the moment. I'm almost 4 months in, and I can't believe the improvement. I bound out of bed in the morning and start getting stuff done. My attitude is positive, excited, eager for the day and being alive. I can't believe it. All those years with the background hum of depression, even if mild at times, made me think feeling that way was normal. It wasn't! This turned out to be the perfect fit for me."

• pwn...
• Taken for 1 to 6 months
• January 25, 2016

"I was prescribed Wellbutrin by my doctor when I told her that I was having a very difficult time getting out of bed and wanting to be productive one month ago. My doc prescribed me Wellbutrin 150 xl, which has as an added bonus made me completely stop smoking and even become repulsed by cigarettes. No negative side effects. Wellbutrin has reduced my urge to drink alcohol by 90%, and when I do drink, I feel intoxicated after only 2 or 3 drinks. I have been exercising five days a week and eating well to assist in mood elevation. I have more motivation and energy now than a month ago. I am impressed with this medication."

• Can...
• August 20, 2015

"All I can say is Wellbutrin has substantially increased my quality of life. I was so scared about side effects that I waited years to try antidepressants. I was on Celexa, and when that failed, I was put on Zoloft, which also did me no good. Wellbutrin not only brought me out of a deep depression, it's caused me to be active, and my weight is now in the normal range. I'm also more organized and positive than I've ever been. My family members, who were initially against me taking Wellbutrin, have changed their opinion because they see me enjoy life again."

• Anonymous
• June 18, 2009

"I have recently decided to start Wellbutrin after 2 years on Zoloft. Although I felt the Zoloft worked well, there were some unfortunate side effects. I asked my doctor if I could give Wellbutrin a try (I had also recently picked up smoking again so I mentioned that). Well, here's the good news... my mood has remained stable (I simultaneously tapered off the Zoloft). I have been better able to focus at work, cigarettes tasted disgusting, and I have noticed a decrease in my desire to engage in compulsive activities. The cons... food doesn't really taste all that great, I'm extremely thirsty, and I was initially a little on edge at first (this has since gone away). The other surprising effect was a marked improvement in sexual response."

• win...
• Taken for 1 to 6 months
• June 5, 2014

"Wellbutrin is amazing. Prior to Wellbutrin, I was put on Zoloft, Prozac, and Valdoxan, all of which either killed my sex drive, did nothing, or made me too sleepy to function. For 2 years, I stupidly went off medication and just thought everything in life was crap, and probably said some things I regret to people. Eventually, it came to the point where I was failing at work and angry at everyone. The ADHD medication I was taking also worsened my depression. With Wellbutrin, I have been on it for around two months, and I feel great. I have energy, more motivation, increased libido, and I feel content, although I still have moments. Also, I have lost more than 5 pounds without dieting or exercising."