Bupropion for Sexual Dysfunction, SSRI Induced User Reviews (Page 3)

• Edward
• Taken for 1 to 6 months
• March 26, 2018

"I was on Zoloft for depression for many years. It controlled my depression but I needed periodic breaks because it caused delayed ejaculation i.e. it prevented orgasm which really frustrated our sex life. After finally discussing with my doctor, I was prescribed Buproprion HCL XL 150mg. Within a week the delayed ejaculation problem has thankfully disappeared. I am also finding that this drug has had a favorable effect on my mood swings as it seems to better smooth them out. Have had no negative side effects so far. As a result, I am very happy with this drug."

• Anonymous
• October 5, 2020

"I lasted 3 days on this. I had been taking lexapro for 1 year at 10mg and was up to 20mg. A few months after that my libido had entirely gone, I gained 20lbs and wasn't able to focus. My dr switched me to Wellbutrin. Huge mistake. Day 1 I was full of anger followed by bouts of anxiety and crying. I was sent home from work and put on leave for my mental instability. Day 2 I was extremely irritable and crying every few hours. Day 3 was the deal breaker. I was home alone and randomly started crying. Crying turned into a major panic attack and from there I was thrown into a state of hysteria. I had to call my mom to come over and it took her 3 hours to calm me down. I immediately stopped taking it. Im 28 with 2 small kids. I couldn't afford to let them see me that way and honestly was terrified of what had happened on the 3rd day. It seems to either work really great for some and really bad for others. I highly suggest taking precautions when starting this medication."

• Alora
• October 30, 2016

"I must be far off from where I should be, hormone-wise, because I've only been on this Medicine for one full day when I woke up extremely aroused. I'm not taking this for libido, but for depression. A nice side effect, although I imagine it will balance out soon."

• Dream...
• Taken for 1 to 6 months
• November 30, 2022

"I was prescribed Lexapro for Persistent Depressive Disorder and GAD. It did wonders for my anxiety and helped my depression a bit, but for the last 3 years, I've had no desire for sex. I can't get aroused, and I can't have an orgasm. Sick of living like this, I talked to my psychiatrist about it. He immediately prescribed this. After a month, I feel my libido coming back. It's an actual miracle."

• Big...
• Taken for less than 1 month
• April 12, 2021

"Delayed ejaculation has always been an issue for me. Certain SSRI's made this much worse (particularly Zoloft). Welbutrin was a Godsend for a while until I realized how agitated it made me. The sexual function was great, but I couldn't accept how on edge I was."

• India...
• Taken for 1 to 6 months
• November 29, 2016

"This is my third time on this medication for depression. I struggled with e.d. off and on. In June I started testosterone replacement therapy. It had me feeling like I felt in my early 20s. My wife couldn't keep up. I suffer from anxiety and depression, so my doctor recommended that I start Bupropion again. I believe that it causes sexual dysfunction in men. For the last month and a half, I have had no desire to have sex with my wife and I wake up with the most weakest erections possible. I'm still on testosterone replacement therapy and having suffering again with e.d. Today is November 29, 2016. I'm stopping the pill and will take my chances with depression and anxiety until I'm prescribed something different."

• Smitty
• Taken for 5 to 10 years
• August 3, 2020

"The Arthritis doctor put me on Cymbalta for pain, but after a week or so I couldn't have an orgasm, erections were ok but couldn't get off. The wife tried to no avail. Talked to the doctor and he advised me to check my Urologist. Which checked me out and found nothing wrong. So I went online a for sex therapist that would take insurance as most only take payment at office visits. The therapist recommended this but didn't tell me if it worked or not. Wellbutrin for 8 years now & it's awesome. It took 3 weeks before I felt any improvement but the kick was amazing! Sensation has returned along was great. I have stopped Cymbalta after back surgery but still, use Wellbutrin 200XL daily, just using a shower handheld unit is great also. LOL, The therapist was happy that it worked well as she said some men really have good results as women but doesn't do so well for others."

• MrQuick
• Taken for 1 to 2 years
• January 9, 2017

"I have been taking welbutrin for about a 18 months. At first my libido came flooding back as it does whenI am no longer feeling the pangs of deep depression. It eventually settled in to normal levels but my main problem is my endurance! I have always been able to go the distance more or less but these days I climax in 60 seconds every time! It doesn't matter if we just had sex 5 minutes ago....60 seconds and I spill the beans!! I am a 37 year old male so maybe time is catching up with me??? Idk..."

• Drumm...
• Taken for 1 to 6 months
• February 14, 2022

"Bupropion has been a god send. I’m a 65 year old male who was on Paroxetine and because of that given up on sex. Paroxetine had got rid of my ability to orgasm or ejaculate. My doctor put me on bupropion XL 150mg and what a change. My mood is stable and depression has remained under control. But my sex life has come back with a vengeance. Orgasms are insanely intense and long lasting. I am in a constant state of semi arousal. I am beginning 300mg daily so that will be interesting. Emotionally I’m not sacrificing anything but gaining back my sex life. A win-win."

• Chris...
• Taken for less than 1 month
• May 19, 2020

"Was on Zoloft and Trintellix for a year. I had sex drive and some hormone replacement therapy as well. It just killed my orgasms. I was cocked and load and could not shoot. Very frustrating for me and whoever I was with. Very excited about starting Wellbutrin. Most others just kill it. If I could get and erection it would just fade away and block the getting over the edge. SSRI's not my friends."

• Chase
• Taken for less than 1 month
• July 29, 2021

"Male-34 I started taking Bupropion 2 weeks ago (150MG per day) as requested by my doctor. Now I can no longer get a real hard erection or have an orgasm. I'm well endowed so I figured it took more blood flow to achieve the result I was wanting, so I took a 100MG Viagra tablet I got from a friend. After about 30 minutes I could achieve a full erection but still could not have an orgasm. It was like all the sensation in my penis was gone. It's very frustrating to say the least as it does in fact increase your libido. As of today I will no longer be taking this medication. Hope things get back to normal quickly."

• John
• Taken for 1 to 6 months
• September 1, 2022

"I was on Buproprion for 2 months. I switched to Zoloft which I think was a mistake. I don't think I gave the bupropion long enough of a chance. The last week that I took it I noticed I was "happier" but I had already began weening myself off it. I am putting in a request to my doctor to go back on it. As for sexual related stuff I will say it made me last longer and my "ejaculant" was about 4x more than the normal. No joke it just kept going and would shoot far like in the adult films. Crazy stuff and I want to get back to that. I long for it."

• AJP
• Taken for 1 to 6 months
• December 29, 2022

"This actually gave me anorgasmia despite being used to improve sexual function. It improved libido and ED somewhat but absolutely zero feeling from orgasm. It is not a typical response but beware, it can happen."

• Mat...
• Taken for less than 1 month
• September 13, 2016

"I used Wellbutrin it for a month to start stopping smoking. I used it as you should use Zyban (first week one pill in the morning, then the next two months two pills a day with min. 8 hours in between, best long before evening). After 2 weeks of use I lost a lot of libido and nearly all ability to get fully erected. Now I stopped it by eating one per day for a week. Since two days I've fully stopped and am still waiting on the libido and erectability I had before that idea stopping smoking and eating Wellbutrin...."

• Hiker...
• January 9, 2018

"I have been taking antidepressant and anxiety medication for 30+ years. You name it, and I've taking it. I have been diagnosed by several doctors and psychiatrist as bipolar, and manic depressant. After 23 years I finally got tired of all the meds and went cold turkey and stopped taking them all. My doctor put me on Wellbutrin/bupropion to calm my nerves and depressed moods... (SSRI's) was causing me sexual side effects. Just after 1 month it helped with my depression, but it caused erectile dysfunction. Then I had to go on the expensive Cialis medication to help with my ED...BTW... Bupropion didn't have any effect on my libido."

• Chuck
• Taken for 1 to 6 months
• February 23, 2020

"I was started on Wellbutrin sr 150 bid. This was added to my Cymbalta 60 mg mg qd. I have an a lot of trouble maintaining an erection and having an orgasm. I am on Testom injection twice a week for quite some time so I know that is not the problem. It has helped w my chronic fatigue"

• Jwright
• Taken for less than 1 month
• February 18, 2017

"This medication triggered a panic attack 2 hours after taking it. I suffer from panic disorder but it is well controlled with medications. This medication felt like it nullified my other medications and I had a panic attack the likes of which I haven't seen in months. I finally was able to cobble together a medication cocktail that calmed me down, it made me sleep but I would rather sleep than be in a panic attack. I would totally NOT recommend this if you have anxiety or panic issues."

• Worked...
• Taken for 1 to 6 months
• May 30, 2023

"Started on 75mg twice a day. Felt mood improvement in about a week. The only major side effect I have experienced is extreme horniness. Thoughts of explosive sex go through my mind constantly, even in my dreams. I’m in a much better mood and significantly less irritable, but the constant desire for sex is disturbing."

• Bupro...
• Taken for 1 to 2 years
• April 29, 2022

"For the first few weeks I experienced increased sex drive, I lost a few pounds but if I took it too late in the day, I had trouble sleeping . After the initial effects wore off, I noticed my orgasms have gotten really strong, some so powerful it almost hurts. I’ve never felt anything like it. That’s been a side effect that hasn’t subsided but I am definitely not complaining."

• Ememem
• December 14, 2016

"I added this to my dosage of Sertraline because I was always tired and foggy and sex had become really difficult. It initially helped for these issues, but it worsened my anxiety and caused constant fluttering heart. I went ahead and tapered up to the dose the doc told me to start with, and suddenly I began developing horrible hives all over my body. It was easily the worse itching I have ever experienced. My hands and feet blew up like balloons and I couldn't walk as a result for over a week. I stopped taking the Buproprion the day after my symptoms appeared, but they also stuck around for over a week."

• Ray
• Taken for 1 to 2 years
• March 6, 2018

"Helps counter EffexorXR 75mg sexual issues. I have OCD so it agitates that. I take 450mgXL but may drop it to 300mg. It helps if you are tired. It can raise blood pressure. I also take 25mg of Naltrexone and that greatly helps in the sexual side effect department."

• Kar
• Taken for 1 to 6 months
• July 9, 2022

"Oh goodness, where do I start. I was on fluoxetine for depression for 3 ish months and it absolutely tanked my sex drive. Like, for 2 entire years. I maybe had sex 6 times within that timeframe. I stopped taking fluoxetine and didn’t take anything else in case my sex drive came back. It didn’t, at all. I almost lost all hope to be honest. 3 weeks on 150mg/day Wellbutrin- bam. It was like a light switch went off. Better than it was even before taking fluoxetine years ago. I feel like a monster lol. I was certainly skeptical because there’s no *real* scientific evidence that it should help with sexual issues in women, and my doctor expressed that as well. But it was the only medication that my insurance would cover. Dang am I glad that I’ve been prescribed Wellbutrin. I’ve heard that it helps with certain people, and others it doesn’t. It’s worth a shot though. I haven’t really had any adverse effects yet."

• Anonymous
• Taken for less than 1 month
• January 6, 2023

"I am taking 300 mg and by the second day, it has shown a lot of results. Definitely easy to get aroused again, but stimulation is still reduced in quality for me. Still makes everything easier, and perhaps it will continue to increase in function. As for its antidepressant effect, I do think it makes daily life things more enjoyable when I'm not caught up in thoughts. It also may be contributing to better focus for me due to it blocking the reuptake of norepinephrine. The main side effect which goes away in 2 weeks for me was a dry mouth. I would really recommend trying this drug in general. Definitely isn't an unwelcome addition to my daily meds."

• nel
• Taken for less than 1 month
• April 19, 2018

"When I started taking zoloft I noticed the decrease on my libido. Its hard to have an erection and orgasm its really frustratin. I am 41 year old guy and I am very active, but since I've taken the zoloft the sexual side effect is horrible. So now I've ask my doctor today what is my option here. I am not happy with the side effect on zoloft. So he prescribed me a new meds call wellbutin, it seems like a few lower side affect with this meds so I am really hoping that it will work. For me ... cross my fingers hopefully this will work for me ..with out the sexual side effects."

• 2x52x6
• Taken for 1 to 6 months
• September 19, 2022

"50 year old male. I was put on Strattera for ADHD and it helped with that concern, but in turn it caused my orgasms to be completely lack luster. My drive stayed normal (high for me at my age), no problems getting/staying erect, but my orgasms and ejaculations were sub par. I talked to my NP about this and she said "I'm going to send a prescription over for Wellbutrin. You don't have to take it, but I think you'll like it" Well, I definitely like it. It's made orgasms as good or better than they used to be and my ejaculations seem to have more volume and certainly more power. The only 2 unusual things now are I have A LOT of pre-ejaculate as I approach climax and after I actually climax my penis, just my penis (shaft) aches harshly for 30 seconds to a minute. It's very odd, but I've become accustom to it. It beats the bland finish Strattera caused me."