Bupropion for Sexual Dysfunction, SSRI Induced User Reviews (Page 2)

• No ...
• Taken for less than 1 month
• February 2, 2013

"Male 59, in excellent health, no prior problems. Started taking bupropion 3 weeks ago as adjunct to citalopram. Seems to have improved my mood, but for the past 2 weeks, I have not been able to achieve orgasm. Erections are fine, just now cannot get to the happy ending. I am stopping this medicine."

• Sho...
• Taken for 1 to 6 months
• July 3, 2020

"39, male from the UK. I was experiencing some depression, and because of it, I went to the GP. She prescribed me Sertraline 50 mg a night. I didn't know that stopping it abruptly would cause severe erection dysfunction and loss of libido. My sex drive was fantastic while I was on Sertraline. If I knew that stopping it would kill my sex life, I would not have done that. I used to have sex 5-7 times a week. However, I have not had sex for 10 days now, it is really frustrating and unfortunate. Please, guys, share some of your experiences with me. At this stage, what should I do? Should I resume taking Sertraline or switch to the bupropion class of medicines? I just want my sex life back. Thanks in advance."

• lov...
• September 25, 2011

Bupropion "I was put on 150 mg of Wellbutrin twice a day. It has completely helped my depression and amped up my sex life. Things could not be better. Our sex life has always been amazing but without the depression in the way it's even better."

• Nin...
• Taken for 6 months to 1 year
• August 10, 2016

"I've been on Prozac for just over a year now, and one of the side effects for me was decreased libido (it was almost extinct before the Prozac), and my psychiatrist thought adding this would help. I was excited because of the supposed weight loss and appetite suppression that goes along with this medication. Unfortunately, it did not help me weight-wise, but my libido went from 0 to 100! My husband couldn't keep up! I'd never, and I mean NEVER, been that ready to go in my whole life. After a few weeks, the effects wore down to more like a 20, so I still have that desire, just not 6 times a day (seriously). I called it my women's Viagra, lol! I also managed to quit smoking last year while on this too. Yay!"

• Dar...
• Taken for less than 1 month
• May 11, 2024

"I am 60 years old, my sex drive was non-existent. As a woman, I was very scared that my marriage would be in trouble. I started taking bupropion as an add-on to my current antidepressant. I had gained weight because of my depression, and my doctor said it would control my weight gain. Well, not only did I lose weight, but my sex drive has completely changed. We went from having sex once a month to 3 times a week. I have never felt so good. I swear it works, believe me!!! I take 150 mg a day."

• Swi...
• Taken for 1 to 2 years
• May 31, 2017

"I have been on anti-depressants/anxiety medications for the last year now and have been on 3-4 (Lexapro, Celexa, Trintellix, and Wellbutrin) to try to find one that doesn't give me sexual side effects. Lexapro made me feel the best but has the worst sexual side effects. Wellbutrin was my last hope, and sadly, it hasn't worked for me at all!! I see so many posts on here that say it is magical, which is great for many of you but so hard to believe. I still want to have sex but can't reach an orgasm the conventional way. I have lost all sexual sensation, and that is so depressing because I never had issues in the past. Like another person remarked, I would rather deal with my anxiety than deal with these side effects!"

• Anonymous
• October 23, 2010

Bupropion "I was put on 100 mg Wellbutrin for PMDD issues and stayed on it for about three years. I ended up having many side effects, such as added anxiety, horrible headaches, and constipation. I also lost some weight. However, the mood swings stopped, and I have to say sex was never better. It added to my sexual response for sure, and I really miss that part. If not for the constipation and heart flutters, I would have stayed with it."

• Dru...
• Taken for 1 to 6 months
• September 4, 2013

"I have tried several anti-depressants, and this is the only one that has not taken away my libido or ability to reach orgasm. No libido can cause depression, the whole point of taking these medications. I have not mixed bupropion with an SSRI, so I can't give an opinion on the two together and how they interact on sexual issues or lack of. So for those wondering (men especially), this medication will give you energy and NOT affect your sex life negatively."

• all...
• Taken for 1 to 6 months
• November 29, 2016

"36, female. I have been on Lexapro 10 mg since late March '16. I'm very active... running, hiking, yoga, and still managed to put on 10 lbs in 6 months, and the sexual side effects suck! Pdoc added Wellbutrin XL 150 mg/day to try to help with SSRI-induced SE. I have been on the WB for 2 days now, and I could not believe that it already brought back much of my libido, as well as sensation and faster orgasm. I hope this keeps up-if so, the WB/SSRI combo may save us all! Good luck! UPDATE (3 mo use): Wellbutrin XL is still doing wonders for my depression. It still helps with sexual side effects from the Lexapro, but not as much as the first week mentioned above. Def helping but not eliminating. I'll still take it though b/c I def need some serotonin too."

• 22F...
• Taken for 1 to 6 months
• August 19, 2016

"Have found it impossible to orgasm on this medication, and I will be in the middle of sex and suddenly lose all drive. It helps with everything else, but I'm in my prime. I miss the crazy sex I used to have."

• Ava...
• Taken for 1 to 6 months
• December 27, 2020

"I was on 10 mg/day of Prozac for over 10 years, and it didn’t seem to be working anymore. I got depressed recently, and the psychopharmacologist added 125 mg of Wellbutrin (alternating dose of 100 mg and 150 mg), and I’ve tapered down the Prozac to 5 mg/day. While I’m glad my energy has increased, my sex drive has actually gotten too strong, especially since the Wellbutrin has made it so I can’t orgasm. It’s extremely frustrating, and I find it embarrassing to talk about with the doctor. It’s nice to have my sex drive back after years of it being low, but horrible not to be able to orgasm. It’s making me irritable."

• SIA...
• Taken for 1 to 2 years
• August 19, 2018

"My doctor switched me to bupropion 300 mg because Zoloft caused me sexual dysfunction. When I was changed to it, at first it was great, I had orgasms again, but after being on it for over a year, I have lost interest in sex. When I have sex, I couldn't have an orgasm, so needless to say, I'm no longer taking this medication."

• Har...
• Taken for 1 to 6 months
• March 31, 2023

"Please do not take this medicine. I took this because of my depression, and I took it only for a week, maybe a month at the longest, until I found out I was pregnant with my son. In that short amount of time, it caused my vagina to be dry, and I don’t like sex because it is uncomfortable and it feels like my skin is ripping apart, and I can't orgasm anymore. It has been like 5 years since I took it, and I still have these problems, and I don’t think there is a way to fix it. I hate myself for this. I cry all the time."

• You...
• Taken for 1 to 6 months
• November 22, 2017

"I was prescribed this drug for my depression, and I've been on it now for about 6 months. It's definitely made me a happier person overall. I feel great until I try to have sex... I'm 24 years old, and the only significant change in my life recently has been this drug. At first, I thought it was me, but I'm convinced it's the drug. I used to be a stud in bed, but now it's nearly impossible for me to get hard. I'm going to talk to my doc about getting off this pill before it ruins my relationship."

• AJH...
• Taken for 5 to 10 years
• December 13, 2021

"I have read some of the comments from people here stating that there is no clinical evidence showing proof that Wellbutrin helps with sexual issues. This is not an accurate statement. My wife takes this medication, and it indeed works. Clayton, A.H. et al. “A Placebo-Controlled Trial of Bupropion SR as an Antidote for Selective Serotonin Reuptake Inhibitor-Induced Sexual Dysfunction,” Journal of Clinical Psychiatry (2004) 65:62."

• Wei...
• Taken for 2 to 5 years
• September 15, 2016

"I love this pill! I call it the happy pill! 32f. After the first few months of nightmares, I've become the happiest person alive. After reading all the comments, my sex drive seems to have increased, but reaching orgasms has been hard. It does give me energy. I quit cigs. And it possibly lowered my blood pressure. I can't comment on the weight part 'cause I'm already chubby and love food. I've been way more nice and friendly to people too."

• Bul...
• November 24, 2017

"I’ve been taking Zoloft for three months, and after one month, it was damn near impossible to orgasm. I still had the desire for sex and would reach the peak before the orgasm, however, the orgasm would never come! It was so frustrating that I gave up on even trying. I told my doctor, and she added the lowest dose of Wellbutrin. I’ve been taking it for four days, and I’m proud to say I had an orgasm within two minutes the other night. I also feel a lot better and a lot more calm. I also like how I’m able to focus on a task like I used to pre-medication. With the Zoloft, it made me so lazy and even took away my good anxiety. I have a high metabolism and felt the effects of Zoloft and Wellbutrin within the same day, which isn’t typical."

• Edw...
• Taken for 1 to 6 months
• March 26, 2018

"I was on Zoloft for depression for many years. It controlled my depression, but I needed periodic breaks because it caused delayed ejaculation, i.e., it prevented orgasm, which really frustrated our sex life. After finally discussing with my doctor, I was prescribed Bupropion HCL XL 150 mg. Within a week, the delayed ejaculation problem has thankfully disappeared. I am also finding that this drug has had a favorable effect on my mood swings, as it seems to better smooth them out. I have had no negative side effects so far. As a result, I am very happy with this drug."

• Bob...
• Taken for 1 to 6 months
• March 10, 2019

"Love that it helped take the edge off my depression. But I’m 35 and have a horrible time now getting hard (erectile dysfunction) - I’m stopping it today to see if in a few days, it’s better. Needless to say, I hadn’t had a problem before taking it."

• Alo...
• October 30, 2016

"I must be far off from where I should be, hormone-wise, because I've only been on this medicine for one full day when I woke up extremely aroused. I'm not taking this for libido, but for depression. A nice side effect, although I imagine it will balance out soon."

• Big...
• Taken for less than 1 month
• April 12, 2021

"Delayed ejaculation has always been an issue for me. Certain SSRIs made this much worse (particularly Zoloft). Welbutrin was a godsend for a while until I realized how agitated it made me. The sexual function was great, but I couldn't accept how on edge I was."

• Anonymous
• Taken for 1 to 6 months
• April 27, 2023

"I really, really like bupropion. I’ve been on all the main SSRIs over the years. My most recent expedition was with Zoloft, which was terrible. Truly the worst experience I’ve ever had. I had every single symptom, and it exacerbated all my anxiety. I kept hoping it would help, but it never did. I could also barely orgasm. At some point, I got frustrated at feeling numb and sexually dysfunctional and got a script for bupropion since it worked well for my brother. Oh my. Things changed. I’ve tapered off the Zoloft, stayed on the bupropion, and feel better than I have in a year. My sex drive is crazy - my boyfriend is overwhelmed. Very grateful I found something that works for me."

• Dre...
• Taken for 1 to 6 months
• November 30, 2022

"I was prescribed Lexapro for persistent depressive disorder and GAD. It did wonders for my anxiety and helped my depression a bit, but for the last 3 years, I've had no desire for sex. I can't get aroused, and I can't have an orgasm. Sick of living like this, I talked to my psychiatrist about it. He immediately prescribed this. After a month, I feel my libido coming back. It's an actual miracle."

• Ind...
• Taken for 1 to 6 months
• November 29, 2016

"This is my third time on this medication for depression. I struggled with e.d. off and on. In June, I started testosterone replacement therapy. It had me feeling like I felt in my early 20s. My wife couldn't keep up. I suffer from anxiety and depression, so my doctor recommended that I start bupropion again. I believe that it causes sexual dysfunction in men. For the last month and a half, I have had no desire to have sex with my wife, and I wake up with the weakest erections possible. I'm still on testosterone replacement therapy and have been suffering again with e.d. Today is November 29, 2016. I'm stopping the pill and will take my chances with depression and anxiety until I'm prescribed something different."

• Wow...
• Taken for 1 to 2 years
• June 6, 2016

"Male 30. I've been taking it to control ADD and depression, and as a pleasant side effect, it allows me to go 2-3 times a night if she'll let me. I have not been this horny since I was 13. Thank you, magic chemists, for making this drug."