Mydayis and Depression: What Users Say

• Jal...
• Taken for 1 to 6 months
• September 17, 2017

For ADHD "Mydayis 50mg has worked great for me. It did take a week or so for me to notice any real benefits. The first day, I was a bit on edge. Then, I was slightly depressed for about a week. It wasn’t major depression, just a general “down” feeling. After the second week, I have seemed more focused. My energy and motivation seem to be increasing slightly. This drug has a very smooth transition. I don't crash or have periods of high heart rates and anxiety. I was on Adderall 30mg previously. I also have tried Vyvanse and Concerta in the past with poor results."

• spl...
• Taken for less than 1 month
• August 6, 2018

For ADHD "I switched from Adderall to Vyvanse, then back to Adderall because the Vyvanse was too expensive, then switched to Mydayis. I'm glad other people are also saying what I'm feeling. Takes about three hours to notice anything. First, I start sweating a lot, with some slight chest pain. Do not feel motivated or focused, actually the opposite. Mydayis is making me scatterbrained and depressed. I was in a good place before I started with this medication. Hopefully, I can get back to good mental health when I stop."

• Mea...
• March 12, 2021

For ADHD "I took Mydayis 37.5 mg for 2 years. I just recently ran out and decided to wait a week to refill. I cannot believe the change in myself! While on it, I became withdrawn and too focused on one specific thing. I cut out people and ruined my small business. I didn't feel human! I can't explain the feeling, but now that I haven't taken it in a week, I feel like myself again! I was just flesh living day by day on Mydayis! I will NEVER touch it again! Please tell me there are others out there with similar experiences."

• ups...
• Taken for 1 to 6 months
• September 7, 2018

For ADHD "I've been taking Adderall XR for 5 years now, and it's been working fine, but my doctor offered for me to try Mydayis so that it would last a bit longer. I've been taking Mydayis 37 mg for 2 months now and have become increasingly irritable, VERY DEPRESSED, and unmotivated. I even relapsed with self-harm, which I haven't done in 6 years. I also had my first extreme panic attack. I was finally in a good mindset before I took this, which took YEARS of therapy and medications. If you have struggled with depression in the past and still struggle with it occasionally, I would not suggest this drug AT ALL."

• JJa...
• February 14, 2019

For ADHD "I do not like this medicine at all. I feel awful! I screwed up on my test and studying because of it. It is not for me. I was on Vyvanse, but the only issue that I had with Vyvanse was that it only lasted 4 hours! I miss Vyvanse so much. It made me feel so good and more confident, and my focus was on a thousand, and it helped with some anxiety! My doctor and I wanted to give Mydayis a try because it lasts longer. It does last longer, but I feel depressed, lazy, less focused, and just drugged, and that's it. I'm calling my doctor tomorrow to let him know I can't stand this drug at all! I want Vyvanse back right away. I really do hope that they can accommodate me. I will give this Mydayis to the pharmacy so that my health insurance will know that I'm not trying to keep it. It's been only a week since I have been on it. I'm not a fan at all. I want off. It's messing me up."

• ADD...
• Taken for 1 to 6 months
• December 28, 2018

For ADHD "I received Mydayis 25 mg 2.5 months ago for severe combined type ADHD (also started Lamictal at that time). After taking the 25 mg dose for 2 months, I was not impressed. Mydayis seemed to work OK when beginning Lamictal, but the effects declined as the Lamictal titration from 25 mg to 200 mg maintenance dose. The benefit of Mydayis was increased alertness on the morning commute to work and a general calming. My focus and concentration remained impaired. The Dr bumped Mydayis to 37.5 mg and feel calmer and less impulsive, and alertness is increased to the point of insomnia. No relief of concentration or problems forgetting things, losing items, etc. In fact, I feel quite depressed and drugged."

• Ale...
• October 4, 2017

For ADHD "Taking 25 mg right now and was on Adderall XR 30 mg. I don't understand this medicine since it usually makes me tired and down for about 2-3 hours after taking it, then get an okay amount of focus for another 6-8 hours. I personally can't deal with those 3 hours every day when I need to be productive, so I will try something else. This drug may be very similar to the chemicals in Adderall, but it definitely does not feel like it."

• AZ1...
• Taken for less than 1 month
• March 19, 2018

For ADHD "Switched to this because Vyvanse 70 mg was wearing off too soon (I take my meds around 6 am and it would wear off by 1-2 pm). It's been about 2 weeks now, and I'm depressed, grouchy, and accomplish nothing in the morning until about 10 am when I am almost overly focused. I feel moody, more overwhelmed than normal, and it does not have the calming effect on me like Vyvanse did. I'm going back to Vyvanse for sure and going to ask about an afternoon pill to get me through those last couple of hours of work."

• Geo...
• Taken for 1 to 6 months
• August 27, 2018

For ADHD "I've been on this medication (25 mg) for a few weeks. Didn't notice it kick in till a few hours after taking it. Felt nervous and anxious most of the day, had no appetite. Felt like I was going to cry all the time and just depressed."

• lor...
• November 9, 2017

For ADHD "I can't believe all these negative reviews! The only praises I hear are ones that sound like 'stage actors' who are planted into these websites and are being paid to boast about the wonders of this medicine. This medication was created because Shire no longer held the patent of Adderall, so they came up with a new drug for doctors to push so Shire could make more money again. At the same time, all the generics of Adderall that were so great are now weak and inferior. I've never been so depressed and feel there is nothing to look forward to anymore after having Adderall pulled out from underneath my feet. I just plug through my days just to get the day over with. My family suffers due to big pharma greed!"

• Sum...
• Taken for less than 1 month
• September 13, 2017

For ADHD "Meh. I was on Vyvanse, 70 mg/day and switched to Mydayis 25 mg/day. NOT what I was hoping for. Not by a long shot. While it 'lasts longer' than Vyvanse (was on Vyvanse for years) which only gave me about 5 to 6 hours in the end, it gives me much less motivation. Makes me depressed. I'm very sorry I did not only get only a 2-week supply rather than 1 month. I have no insurance, and it was about $100 more than Vyvanse. Needless to say, I will request Vyvanse again at my next appointment. BIG DISAPPOINTMENT."

• Jul...
• Taken for 1 to 6 months
• January 4, 2018

For ADHD "I started on Mydayis 37.5 mg 12/09/2017. Previously, I took Adderall XR 60 mg daily. Adderall was working fine except the big drawback was I’d crash and have no focus after three o’clock in the afternoon. This would lead me into a vicious cycle of wanting another Adderall just to be productive. At the end of the month, I’d run short of my Adderall and go “in a tank.” This infuriated my husband because he didn’t understand what I was going through. Since I was tired of this cycle month after month (my FNP would not increase my dose), I did some research and found out about Mydayis. I am taking 50 mg now, and it’s been a game changer. No more crashes! I did feel depressed the 2nd week, but it passed. I’m really happy I found this medication."

• Anonymous
• Taken for 1 to 6 months
• March 21, 2018

For ADHD "What's throwing me off is seeing many experiences saying they couldn’t feel Mydayis working for 4+ hours. It starts off with a small instant release, so I do feel mine working right away. Side effects are different for everyone, but for comparison purposes: Adderall XR 30 mg worked 6-7 hours, then sleepiness and a hard coming down/depressed feeling, loss of appetite, calming effect - helped rationalize my emotions effectively. Mydayis: 12 hrs, still feel working within first 30-60 mins like Adderall, my appetite came back with this, no coming down feeling, but the overall effectiveness of helping with focusing sometimes isn’t as much. I’ve thought about increasing, but I’d like to see about therapy for self-management or at least a low dose. The doc also said if this dose doesn’t work as well that we’d switch to Vyvanse, which is one I haven’t tried, so I’m afraid to switch. Overall, this one has worked best for me, but I am looking at healthier avenues in the near future."

• DJT...
• Taken for less than 1 month
• September 19, 2018

For ADHD "Started 25 mg Mydayis about three weeks ago. Was on 30 mg Vyvanse. Vyvanse was good, but it took two hours to kick in and wore off about 5-6 hours after it kicked in for me. (I am likely a fast metabolizer.) I am now feeling lazy, a little depressed, and I am eating more food. I cannot tell when it hits or wears off. Doesn’t feel like it’s doing much. Maybe my dose was too low? Not sure if I will try a higher dose or change back to Vyvanse. Wish I knew how to compare dosages between Vyvanse and Mydayis."

• Boo...
• Taken for 1 to 6 months
• January 6, 2018

For ADHD "Mydayis has been a game changer for me. I was on 60 mg of Adderall XR for years, and I’d lose focus in the mid-afternoon, so I’d take another one. At the end of the month, I’d run short, get irritable, and sleep until I got my script filled again. Vicious cycle. Mydayis 50 mg keeps me level and on a smooth, even keel all day. I usually take it a few hours before waking up since it does take a while to kick in. After a week of taking 37.5 mg, I did experience some depression, but it passed. I’m very grateful that I started Mydayis. My quality of life has improved greatly."

• Anonymous
• Taken for less than 1 month
• September 18, 2017

For ADHD "It takes too long to kick in, I have to get up hours before I am supposed to just to take it so I am alert at work. I was just sitting here today trying to figure out why I have been so tired and sad, and I started reading the side effects, and now it all makes sense. I am going to keep taking it until my month is up, and if it doesn't get better, I am going back to my Vyvanse and Adderall."

• Anonymous
• Taken for less than 1 month
• March 20, 2018

For ADHD "It's helped, but these side effects are a bit much. Whenever I take it, I often feel depressed. I'm not entirely sure if that's the best way to describe it, but I end up kind of hating myself and not wanting to do anything because I'm a piece of rubbish. This is a common side effect, but I've also been having vision problems, and they've only been happening after I started taking the medication. It could just be a coincidence, but this new farsightedness is definitely out of the ordinary. My parents also needed glasses, but I'm pretty sure neither of them was specifically farsighted."

• Are...
• Taken for 1 to 6 months
• December 30, 2021

For ADHD "I have taken IR Adderall for several years, but the majority of the generics are horrible, and getting name brand was near impossible plus expensive. So I decided to try Mydayis because my insurance offered it as a covered alternative to Adderall. I have taken Mydayis for 6 weeks, and it is awful. I haven’t been myself at all since starting it; I have been depressed, anxious, and agitated. I’ve had zero motivation to do anything. I could take it in the morning, drink a cup of coffee, and an hour later be drowsy enough to fall asleep on the couch. I don’t recommend Mydayis at all, especially if you’re looking for an alternative to name brand Adderall. Even the worst generic Adderall IR is better than Mydayis."

• liz...
• Taken for 1 to 6 months
• January 5, 2023

For ADHD "Mydayis was the most effective drug I have ever taken for my ADHD, and it worked too well. It is very good for getting any kind of work done, but the side effects were so insanely negative that I could not handle taking them any longer. I was prescribed Mydayis 25 mg, and I would take it on the weekdays for school and sports to stay focused, but it had really affected my sleep, my appetite, my mental health drastically declined, I could not think rationally, and I was so irritable all of the time. The Mydayis had worsened my depression, anxiety, and would trigger me to pick my eyelashes and eyebrows (trichotillomania). While it had me wanting to do my work and I was finally motivated, I simply could not take the side effects anymore."

• Puk...
• March 31, 2018

For ADHD "Quite possibly the worst medication available. To everyone whose lives it changed, try Adderall or Adderall XR. It will change it even better. I'm 32 and have been on 50 mg of Adderall XR for many years. Before that, Vyvanse, but found I was picking at my skin. Adderall XR was cutting out early in the day, and my doctor said try Mydayis. (She also wrote me a script for Adderall, probably because she knew Mydayis sucks). First day. Four hours after taking Mydayis 50, not working. Ten hours, still nothing. I had wasted my day being not productive. Whoever thought four hours before a medication might help you with ADHD was nuts. Or just shire trying to get a new med out there because Adderall is generic. The end of my day was when I had a complete breakdown over dinner. Sobbed for hours and felt so depressed. I tapered down my Adderall to 25 mg and figured I'd give Mydayis 50 another try. Nope. By 3 pm complete sob-fest and in a really dark place. Yeah, Mydayis is $3 a fill with their marketing pack...not worth it."

• Sta...
• Taken for less than 1 month
• January 21, 2018

For ADHD "Previously, I was on 25 mg of Adderall XR and 20 mg of Adderall IR since I would lose coverage so quickly. Mydayis takes longer to kick in but lasts me way longer (10 hours instead of 6). I started my own company, so focus is super important for me. I’m currently on day 3 of 50 mg of Mydayis and feel less speedy than when I had to take extra doses of Adderall IR. I have noticed a slight increase in my depression, but hoping it will pass in a couple of weeks, as others have said. I also just switched from Prozac to Zoloft, so that could be part of it too."

• Act...
• Taken for less than 1 month
• September 14, 2018

For ADHD "ADHD drugs are not supposed to give you motivation or energy, those are side effects of being on too high of a dose."