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Adalimumab for Rheumatoid Arthritis User Reviews

Brand names: Humira, Hyrimoz, Amjevita, Hadlima, Idacio, Cyltezo, Simlandi, Yusimry, Abrilada, Yuflyma, Hulio …show all brand names

Adalimumab has an average rating of 6.2 out of 10 from a total of 136 reviews for the treatment of Rheumatoid Arthritis. 54% of reviewers reported a positive experience, while 34% reported a negative experience.

Adalimumab rating summary

6.2/10 average rating

136 ratings from 147 user reviews.

Compare all 318 medications used in the treatment of Rheumatoid Arthritis.

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Reviews for Adalimumab

  • Mom
  • Taken for 1 to 6 months
  • November 7, 2020

Humira (adalimumab) "This drug should be taken off the market. My daughter had the Rheumatoid Arthritis and had been taking Methotrexate along with other drugs. She was diagnosed with the Arthritis when she was in her early twenties, out of college. She started taking Humira last year, about 6 months into it. She died April 18, 2020. All organs in her body had been compromised by this drug. She was 32 years old. When you take this, you are gambling with your life."

1 / 10
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191 Report
  • Annie
  • Taken for 10 years or more
  • January 1, 2019

Humira (adalimumab) "I was diagnosed with Rheumatoid Arthritis in 1974. I was then 24 years old. Over the years I have been prescribed many different medications - various anti-inflammatory tablets, gold injections, Arava, Methotrexate etc. I have also had surgery on my hands, elbows, feet and a replacement knee. I had many bad periods with pain, swelling and stiffness - all the symptoms that are so well known to arthritis sufferers. But I had some good years also when I was able to go to work. In 2007, after a severe flare up, I was prescribed Humira, 40mg every two weeks. The results are amazing. I haven’t had a flare up since I started using Humira. And apart from a bladder infection, quite rarely, I have had no problems. This year, now 2019, I will be on Humira 12 years and I think it is very good."

10 / 10
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192 Report
  • Cinna...
  • Taken for 1 to 6 months
  • October 25, 2014

Humira (adalimumab) "Humira gave me my life back! I received four different diagnosis by four different Rheumatologists. Diagnosis: Fibromalagia, Connective Tissue Disease, Rheumatoid Arthritis, lastly Lupus. I used to have severe joint pain, mostly in my legs, difficulty walking long distances, inflammation, insomnia, depression, 60lb weight gain from steroids, stomach bloating, joint stiffness throughout the night, I would toss and turn throughout the night due to the stiff achey joint pain. My legs were the most achey, I would cry at night because the pain was so unbearable. I hated when it was time for bed, because I knew pain would accompany sleep with stiffness. I felt like I was 90 years old. I was a"Hot Mess!" Thank GOD for Humira!!"

10 / 10
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Frequently asked questions

  • VRP
  • Taken for 6 months to 1 year
  • March 4, 2019

Humira (adalimumab) "My Father started Humira and within 7 months was diagnosed with Lymphoma (cancer). He had an abdominal CT prior to starting Humira and there was no growth or mass. A CT scan was done 7 months after starting Humira and he had a massive abdominal growth and diagnosed with Large B Cell diffuse Lymphoma. His Rheumotologist and Oncologist both said to stop the Humira immediately and his Lymphoma was caused by Humira. He is currently on Hospice. Please be advised that Humira absolutely does cause Lymphoma in many people and is a dangerous medication."

1 / 10
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  • prv
  • Taken for 1 to 6 months
  • February 7, 2020

Humira (adalimumab) "My Father went on Humira for rheumatoid arthritis. He was diagnosed with non Hodgkins lymphoma 6 months later and his rheumatolgist took him off Humira immediately. His rheumatologist admitted that Humira caused the Lymphoma. My father died a few months later. There is a black box warning that Humira may cause Lymphoma. This drug should be taken off the market! I tried calling the FDA and sent letters and information. No Response from the FDA!"

1 / 10
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Are you taking this medicine?

  • Mark...
  • Taken for 1 to 2 years
  • January 19, 2021

Humira (adalimumab) "At age 52 I began to experience symptoms (swelling, joint pain). After suffering for two months, I was diagnosed with rheumatoid arthritis in Feb, 2019. Was put on prednisone for a few weeks and then began weekly dose of methotrexate. After a few months of this treatment, my symptoms were slowly improving when my doctor decided to start me on Humira. I immediately began to feel better. Well enough to resume living my active lifestyle which includes running 40+ miles a week. Thankfully, any side effects have been minimal to date."

9 / 10
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75 Report
  • Anonymous
  • Taken for 1 to 6 months
  • July 26, 2012

Humira (adalimumab) "I am 47 years of age and was diagnosed with rheumatoid arthritis at 28. I have been incapacitated every day since my diagnosis and for the last 3 - 5 years I have had difficulty driving, walking, shopping and leading a 'normal' life. This has led to a poor quality of life due to constant pain and depression. I started taking Humira about 8 weeks ago. One week after commencing I woke up feeling very strange. It took me a few hours to work out I was completely pain free. I hope it continues to be effective. It has changed my life completely."

10 / 10
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189 Report

More FAQ

  • Zapo
  • September 2, 2014

Humira (adalimumab) "Diagnosed with sero negative rheumatoid arthritis about five years ago. It came on very quickly and pain was awful. Took methotrexate, but was quite ill from side effects. Thought I Achieved remission and stopped methotrexate. Unfortunately, the disease was active and recently had a flare that has lasted for months. Blood work all negative. Rheumatologist ordered an MRI and found bone erosion in the wrists. Started Humira and had relief of symptoms shortly after. Just took second injection. The nurse who instructed me on the shots said to leave it out of refrigerator for 30 minutes, ice the site and inject. I have done both injections in my stomach with no pain. Using the Humira pen. Also iced spot for 5 minutes afterwards"

10 / 10
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163 Report
  • Took...
  • Taken for 1 to 2 years
  • January 6, 2016

Humira (adalimumab) "At 23 my RA got so bad that walking & lifting my hands over my head was enough to make me wince in pain. Doc prescribed me Humira, and my pain went away overnight (literally). I continued taking it for a year, and I haven't had a single notable flare-up since the first injection. I still get random SMALL aches but they're completely forgetabble. Can't say the list of long-term side effects don't scare me. So since I feel 100%, I've decided I no longer want it. Have actually been off the med for about 6 months now and not a single flare-up. Doc pressured me to mix it with Methotrexate, but I'm not a human test subject so that ain't happening. Doctors, please listen to your patients. If they feel great, don't force MORE meds on them."

7 / 10
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135 Report
  • Howard
  • Taken for 2 to 5 years
  • February 5, 2019

Humira (adalimumab) "I had sudden onset acute rheumatoid arthritis at age 58. Severe pain, swelling, unable to work or do much of anything. Rheumatologist put me on Humira after trying various other therapies. Was taking Methotrexate, but that started causing chest pain. The Humira was like magic for a while - the pain was much diminished. I was able to go back to work and resume very active lifestyle. After about 1 1/2 years, the side effects started. Rash at first, then a plaque-like rash with sloughing skin (which is still spreading) on my head, hands. Then boils started - very large, very slow to heal. I have to stop taking it - it is killing my immune system. Really not sure how much damage has been done to my body from this drug. There are significant risks to this drug."

3 / 10
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94 Report
  • PBNYC
  • Taken for 1 to 6 months
  • February 8, 2014

Humira (adalimumab) "I had rheumatoid arthritis onset literally overnight in wrist, and within short period, all fingers, elbows and shoulders. I have negative RF, but elevated Sed Rate. I pushed my Rheumatologist hard to get in front of the disease progression. I was on Methotrexate alone for about 10 wks, increasing dosage from 12.5mg - 17.5mg but it had marginal impact. I pushed for Humira and within 48 hrs after first injection, I noticed improvement. I'm six weeks into combination therapy and I'd say I'm 60-70% improved. Large joints are 90% better but fingers remain stubborn. Yes, the shot hurts for 10 flipping seconds. I let it get to room temp for about 30-40 minutes..speciality pharmacist said that was fine. This medicine is awesome."

9 / 10
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143 Report
  • Regre...
  • Taken for less than 1 month
  • November 17, 2019

Humira (adalimumab) "I've had RA, after a bout of health issues, and finding out I had Pulmonary Fibrosis (PF), from unknown causes. I guess the shock and complications from a lung biopsy pushed my body over the edge. I was started on Prednisone and Sulfasalazine, but got minimal relief. Due to the PF, doctors were reluctant to try biological drugs. I did try Orencia, but had side effects. Was placed on Enbrel, but no Relief. I finally got Humira. I took the first dose and felt strange the next day; panicked. By the next day my life was in utter chaos! I did find that if you're on Benzos, it blocks them, so I was in total withdrawal!!! I had to research that one. 4 weeks later I'm dealing with horrible headaches, depression, vertigo, tinnitus...I just pray this med gets out of my system soon! I read it may take 88-98 days to clear! Never again! No more Biological meds! Prayers for all who are suffering!"

1 / 10
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73 Report
  • Anonymous
  • November 28, 2011

Humira (adalimumab) "I take Humira for rheumatoid arthritis and so far it's the only medicine that works for me. I've tried Plaquenil and methotrexate but they don't even touch the pain/swelling. I began to feel relief the morning after the first shot of Humira. Don't let the instructions scare you. The shot is not painful. I let it stand on the counter 15 minutes before I give it so it's not so cold. My Doctor suggested that I sit in a straight back chair so that the abdominal area is already pinched and you'll have both hands free, then pick a spot on my stomach that's 2 inches away from the navel and just do as the directions explain. You won't feel the needle, but the medication will burn just a little. I can't even say it hurts. Don't be afraid."

10 / 10
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153 Report
  • Anonymous
  • August 27, 2016

Humira (adalimumab) "My mother was taking this drug twice monthly. She had been on it once before for aut 2 years and had great results. She had to stop because of an operation. Later on her arthritis caused so much pain and she requested this medicine again. She took it again for 3 months and was so happy to be able to get around. She then got scratched by her dog, took the shot and by the next morning she had a 104 fever and infection spread throughout her body. She went into a coma state and never came out of it. She died from septic shock 6 days later. Use with extreme caution. Do not use if you even get a scratch or sore as it lowers your immune system and may cause death from an infection."

10 / 10
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105 Report
  • RA in...
  • Taken for less than 1 month
  • September 15, 2013

Humira (adalimumab) "l have had rheumatoid arthritis now for 7 years, it runs in my family both grandmothers, my parents, my 5 siblings. I have been taking methotrexate injections for 2 years plus Celebrex & Plaquenil along with controlled pain medication. I thought is this the way my life is going to be, always in pain. I started Humira about 3 weeks ago & WOW after the 1st injection the next day I could not believe how much my pain and stiffness had decrease, I could actually get up by myself in the morning. I take my shot every 2 weeks, I start noticing about the Friday or Saturday a little stiffness and feeling achy and know its time for the next dose. I have experienced a lot of pain, burning & stinging on the injection site. I have learned what works for me is to lie down."

8 / 10
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132 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 19, 2012

Humira (adalimumab) "I was against taking this medication until my flare-ups were so bad I was not able to walk or use my arm. I am so grateful for this medication. I just had my 3rd dose (every other week). Other than the extreme pain during the shot and a bit unsettled for about 10 minutes after, I say this medication is a miracle. I am 99.75% pain free ~ the first time in over a year. So far no side effects other than very thirsty. Cutting down on coffee and have increased my water intake. I worry about possible future side effects but not being able to move is not living."

10 / 10
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140 Report
  • Kim
  • October 21, 2016

Humira (adalimumab) "I was initially put on Humira a couple years ago for my RA, after a failed attempt with using Enbrel and Methotrexate to treat my constantly inflamed and achy joints. I am pleased to report that with only 6 or so months with using Humira, it launched me into an incredible 2 year remission where I was completely pain free and had my life back. I knew it would be short lived, about 2 months ago some of the aches and inflammation started to come back. I told my Rheumy I wanted back on Humira so she gave me an injection and I took it last week. The arthritis was getting nasty before taking the injection and literally within not even 24 hours of my first injection, SYMPTOMS WERE GONE!! Humira works quickly and effectively!!"

10 / 10
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86 Report
  • Jd7
  • Taken for 10 years or more
  • February 24, 2017

Humira (adalimumab) "When my doctor first suggested humira 14 years ago, I was afraid to start it. I've had juvenile arthritis since I was 15, and am now 50. I was so used to pain, that I didn't remember what it was like to be pain free, that is until I finally decided to try humira. I figured what do I have to lose. I won't know if it works if I don't try it. Honestly, within hours of my first injection I could feel a difference. It really was a miracle drug for me. It lasted 14 years, when it just started losing its efficacy for me. I have learned through research, that your body can produce antibodies to the medicine. Unfortunately when that happens, the medicine will no longer work. I'm going to now have to try something else"

10 / 10
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79 Report
  • Anonymous
  • Taken for less than 1 month
  • July 28, 2012

Humira (adalimumab) "I had my first shot two weeks ago, and my second last Monday. It worked immediately for me. I was able to sleep through the night that first night, after many months of pain and trouble sleeping. I have had active symptoms for about 8 months. I also take methotrexate and Diclofenac. I am in amazement how great I feel! No side effects yet. I'm getting great sleep and can play tennis again. I don't like the injections, but I feel so good... It's worth it!"

10 / 10
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112 Report
  • Twinmom
  • May 4, 2013

Humira (adalimumab) "I began HUMIRA after 3 years of minimal control of my rheumatoid arthritis. I take methotrexate in addition. I am shocked at the quick control of my symptoms and am so happy that I am feeling so much better. I do have some headache and dizziness the next day....but it is sooooo worth it. I highly recommend the self injections vs. the auto inject.....there was a serious reduction in pain with the self injection."

10 / 10
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105 Report
  • Jodi...
  • Taken for 1 to 6 months
  • April 15, 2019

Humira (adalimumab) "I was diagnosed with RA (rheumatoid arthritis) about 4 years ago and my rheumatologist started me on Xeljanz and it was a miracle drug. I was 100% pain free. Unfortunately after a few years it wasn’t working anymore and she decided to start me on Humira and Methotrexate which isn’t doing anything for me. I’ve been on the Humira and Methotrexate for about 2 months now and I’m so discouraged because I’m not getting any relief at all. My feet are swollen, burning, and I can hardly walk. I think I’m going to continue this for another month and if nothing I’m going to talk to my doctor about a different medication."

1 / 10
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57 Report
  • T P
  • Taken for less than 1 month
  • July 30, 2014

Humira (adalimumab) "I was diagnosed with rheumatoid arthritis in 2012, at 25. After an allergic reaction to methotrexate, I was put on leflunomide with great success for a short while. Unfortunately for me, my rheumatoid arthritis has affected every joint in my body. Every flare up is different, but everything hurts at some point. I seeked a second opinion and was immediately prescribed Humira. Like many others, I was given the pen. I must say that the suspense leading up to pushing that button is far worse than the 15 or so seconds of pain. I was given a sample fresh from the fridge at my appointment, and it hurt like hell. My nurse shared with me to let it come to room temp. I do my first at-home injection next week. Hoping for great results."

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90 Report
  • DeeDee
  • September 14, 2019

Humira (adalimumab) "I've been on Humira for 4 months now and the wide spread of pain and respiratory symptoms have been a nightmare. My rheumatologist stopped the Humira because she too had never seen such a bad reaction."

1 / 10
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50 Report
  • Red
  • Taken for 2 to 5 years
  • January 11, 2019

Humira (adalimumab) "Diagnosed RA 2012 tried many meds then prescribed Humira. Worked well for RA but everyday I was getting weaker and weaker. Caused my vitamin d deficiency and also Mono. To top it all I now have lymphoma. Please watch your vitamin d levels. Also I have kidney stones. Tough go trying to get just comfortable."

8 / 10
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53 Report
  • ghost
  • December 12, 2010

Humira (adalimumab) "I have been taking Humira now for about 10 years. First started as study patient and still continue to take it. It has been great. Recently the cost has been the biggest concern. I have tried to take injections a month at a time rather then two weeks. I do not suggest this. Three weeks at a time seem to work great for me. After that the pain starts to return. I am currently researching other medicines so I can stop taking this. The cost is just too high for me. Currently the only long term affects I have noticed is shortness of breath, hair loss, occasional dizziness and fatigue/insomnia. I hope this review helps."

8 / 10
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106 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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