Adalimumab for Rheumatoid Arthritis User Reviews (Page 5)
Brand names: Humira, Amjevita, Hadlima, Hyrimoz, Cyltezo, Simlandi, Yuflyma, Yusimry, Idacio, Abrilada, Hulio …show all brand names
Reviews for Adalimumab
- Not...
- Taken for 6 months to 1 year
- November 28, 2017
Adalimumab "RA and UC. Injection is awful, painful, and leaves horrific rash and bruising. On Humira, RA has not improved, in fact, it has gotten worse. Literally had to get a depo and Toradol injection today for bad inflammation and excruciating joint pain. The nausea is beyond manageable, and the headaches! Side effects are killing me. I really wish I could upload pics of my injection sites."
- ste...
- Taken for 1 to 6 months
- July 7, 2021
Adalimumab "I've been on and off Humira, and now I've been on it for a couple of months. It's not helping at all! I have to take pain pills to be able to move and help with all the pain I have all over. I'm looking into getting on something else."
Frequently asked questions
- What are the new drugs for rheumatoid arthritis (RA)?
- Can you take Humira with antibiotics?
- Cosentyx vs Humira: How do they compare?
- Skyrizi vs Humira for plaque psoriasis - How do they compare?
- JEC...
- Taken for less than 1 month
- December 22, 2020
Adalimumab "Humira was not safe for me. Was on methotrexate, but did not control RA well and kept having to have joint replacements. So prescribed Humira, first injection was okay, did not see any effect, but was told it had to build up. Second injection the next week. The next morning I woke up in trouble! TERRIBLE... rash, facial mask, hives/itching, sores in mouth and throat/eyes. Taken off Humira and told I had a 'lupus-like' syndrome. Was on steroids for months as it stayed in my system for three months before the lupus episode was over. Humira said once it was out of my system, it would be okay (still get hives off and on). I believe it is likely, now reading literature, that PEG (those lipid nanoparticles) in the injection might have been a cause, but no one knows for sure. BAD drug in my case."
- Jul...
- December 27, 2021
Adalimumab "Absolutely unexplainable, horrid complications, however, after reading through their warnings and drug interactions, the experiences have everything to do with my prescribing rheumatologist being negligent and not the drug itself. I had many very severe side effects because, despite fully knowing other conditions I was on, and even some meds with moderate interaction, this should never have even been considered a possible treatment for me. None of this was disclosed to me with the exception that I’d be more prone to infections, however, while it was made clear, it really wasn’t explained well or as possibly serious as it could be. The one thing that had prompted me to even question my now-fired rheumatologist was using the drugs.com app. I keep track of all my meds in, and when I entered Humira, immediately, a major health hazard indicated not just one warning but two, both of which I know they were more than aware of. Coupled with the fact they were also negligent with my first medication."
Are you taking this medicine?
Your review helps others make informed decisions.- Anonymous
- Taken for less than 1 month
- November 3, 2022
Adalimumab "I took one dose of Humira via injection approximately 2 weeks ago. Within an hour of taking it, I felt agitated for no reason. Over the next few days, I had a full-blown psychotic episode. Never had I ever been diagnosed with bipolar. As the weekend progressed and feeling absolutely out of control, angry, agitated, and tearful, I sought the help of a psychiatrist. She immediately diagnosed me with bipolar 2 and put me on a mood stabilizer. Now it’s possible that it had nothing to do with the Humira. I’ll never know. But I also won’t take another Humira injection. I just hope I find some relief at this point."
- Ang...
- June 1, 2015
Adalimumab "In response to Rick. I started Humira and had good results. Then needed to come off it because I injured tendons in my foot. When I restarted Humira, I have not achieved the same results. My joints are red, swollen, and remain in a lot of pain."
More FAQ
- Is Amjevita interchangeable with Humira?
- What is the difference between Cyltezo and Humira?
- What are the new drugs for plaque psoriasis?
- What are biologic drugs and how do they work?
- tra...
- Taken for less than 1 month
- December 3, 2017
Adalimumab "The drug did not work for me. I felt I was about to have a heart attack. I thought I was going to die. I was ready to call 911. I didn't realize it could have such an adverse effect on you. The doctor prescribed another drug, which worked much better without giving me the feeling of an oncoming heart attack."
- Tin...
- April 27, 2017
Adalimumab "I am on Plaquenil and the disease was progressing. My doctor (whom I respect and value) recommended going on Humira. I gave myself the first injection and thought I had gotten my life back. I felt better almost instantly. Unfortunately, eleven days later, I had a huge allergic reaction at the site of the injection and my entire body (head to toe) was covered in hives. I was in pain and very itchy for days. I had to discontinue the use of Humira immediately and was put on steroids to calm everything down."
- Diz...
- June 15, 2010
Adalimumab "I have been taking Humira for three months. In the beginning, my pain worsened, and I got one sinus infection after another. Now I seldom have infections, I think I am more careful. The pain in my hands and feet is much improved, and my elbows and shoulders are a little better. I also have fibromyalgia, so it's hard to distinguish what pain is from what. This week, I am getting waves of dizziness that last for several hours at a time. I also have what feels like a tennis ball implanted in the back base of my skull. At least my hands and feet warm up quicker in the morning."
- Meg...
- Taken for 1 to 6 months
- March 16, 2021
Adalimumab "Worked fantastic for my RA, but at only 23, there was no other reason, besides this medication, for sending me to the hospital for diverticulitis. Some doctors are sure that it was caused by the medication, while my rheumatologist doesn’t think so. However, I am still being switched to Cimzia."
- Ash...
- May 5, 2016
Adalimumab "Using for about a year, a fight to get it due to the cost. It's swings and roundabouts, and at least I can work now, but think I have become more argumentative. I think if I were a bit older, I would not take it. Anyone looking to take it, don't let anyone put you off, it's different for everyone. P.S. When my consultant said one of the side effects was hair loss, I think she was joking with me because the last time I had a haircut was in the '90s!"
- Dan...
- Taken for 6 months to 1 year
- February 12, 2025
Adalimumab "Since starting it, I have had significant shortness of breath, an increase in heart failure. I went from Grade I left ventricular diastolic dysfunction to Grade III. More leg swelling and shortness of breath. I am now off it."
- Ndn...
- September 19, 2016
Adalimumab "I have severe RA plus psoriatic arthritis plus asthma plus osteoarthritis plus osteoporosis, and I just turned 60. I have severe allergies to anti-inflammatories and have had my RA for 30 years. Right now, I am on Humira (can't take methotrexate) and have been for 10 years. Humira really helped at one time but just doesn't work for me anymore. I am in an intense flare that just won't stop. We tried Xeljanz, but my sensitive stomach said no more. I was glad to use the Humira even if I did hold my breath when it came to side effects, nothing major happened, but I miss my thick hair."
- Cin...
- Taken for 2 to 5 years
- October 23, 2022
Adalimumab "After 3 years of Humira for RA, and doing well, I developed plaques on my legs and body! My head, arms, etc. My gums turned bright red and bled while on it. After a biopsy on my leg, it turned out to be a rare side effect of Humira. After I stopped the drug, the plaques went away, and my gums returned to normal. No more bleeding. I can’t believe it took my docs so long to figure it out."
- GTH...
- Taken for 2 to 5 years
- September 20, 2023
Adalimumab "Outstanding results with Humira. My symptoms with rheumatoid arthritis were debilitating. I had issues dressing, showering, etc. Methotrexate alone did not have any effect. Humira caused an immediate suppression of symptoms and within a month or so I was back to being ~normal. My rheumatologist was surprised, as he thought I may be a lifetime chronic pain case. I have been using Humira for just over 2 years now and I have no notable side effects. I use 1 40ml pen every other week."
- Rhe...
- Taken for less than 1 month
- December 15, 2016
Adalimumab "After shot #1, I felt great. After shot #2, I felt like I was having an RA flare. The night of shot #3, I felt like I might have the start of the flu. Within 2 days, I had a high fever, chills, teeth chattering. All my joints were in extreme pain, could not stand, felt dehydrated. Could hear my heartbeat and blood whooshing in my ears. If this happens to you, call 911. I took several Vitamin C, and my husband helped me drink water while waiting for the ambulance. I had blood poisoning due to an infected tooth (did not realize I had a tooth problem until I was violently sick). Your doctor will try to convince you to take these shots. AbbVie, the makers of Humira, are marketing this to stockbrokers. I think my doctor must own stock in AbbVie/Humira. Beware!"
- sdu...
- Taken for 5 to 10 years
- August 22, 2022
"I am a 57 y.o. male and have been treated for arthritis for 20 years. I have been on many treatments and medications. Most of them gave me moderate relief for a while, but never quite did the job. Finally, my doctor asked if I would consider a biologic. She gave me lots of information and left me to think on it for 3 months. I decided to try Humira. It was a game changer for me. I have not had a flare-up in the 7 years I've been on it. And with no side effects. It has slowed down the progression dramatically. I have had to have both MTPJs fused, but that damage was done long before starting the Humira. Different drugs react differently with different people. I am fortunate enough to have tolerated all of the medications I've tried, except for Methotrexate."
- Nan...
- Taken for 6 months to 1 year
- July 21, 2022
Adalimumab "I have been on Humira for 9-12 months and have received excellent results. However, if your Humira Pen misfires (this happened to me three times), the company will do everything they can to blame the patient. I was given every excuse known to man for them to not replace it. They even said, since I took the Humira pen out of the refrigerator the night before my injection, that I had it out too long. When I read the information on the box out loud to them, that it can be out for 14 days and still be used, they got off the phone and said they would have to call me back tomorrow. The next day, they then said, when is your next delivery of medication coming? I told them I just ordered a new one and it would be here the next day. Their response was, well, since you are getting the medication tomorrow, we are not going to replace the three misfired Humira pens. So, they do not stand by their product when it misfires. I was out over $400 because the three pens did not dispense medication!!!!"
- Dor...
- January 24, 2022
Adalimumab "Today is the first time that I have had a side effect. I've been on it for 5 months for RA. I have a rash at the injection site, and swelling burns a little too, just like a bee sting. But this doesn't bother me. I think I might not have left it out of the fridge long enough, not stopping it for anything. Helps with my stiffness."
- End...
- Taken for 1 to 6 months
- September 16, 2019
"Was taken off Humira ASAP when it was discovered I had massive fungus growing and living in my sinuses! Had to have (FESS) - bilateral functional sinus surgery! With general anesthesia and the whole surgery experience. Great! Been on so many biologicals, and none work or cause more harm than good! Currently, my DR assured me that bringing out the big guns (IV infusion of Actemra) would finally end my endless everyday flares going on 10 months! So far, after 3 months of infusions, STILL everyday flaring. I do know that after taking all these biologicals, I need to now take high blood pressure medication and also Lasix from water retention! Never had to take all this extra med before biologicals! The only thing that helps the painful flares in my wrist and shoulders is the dreaded prednisone! I think there is no treatment out there for me."
- Ann...
- June 9, 2009
"I have had arthritis since I was 13. I am now 24. This is the first time since taking multiple medications that I have noticed a significant improvement. I have rated 7/10, with the only issues being the pain of the injection. After being on the drug for two months, I have regained complete flexibility in my knees. I still find it difficult to kneel and bend. Hopefully, this will come in time, but a definite positive improvement so far. Just wish I'd had it earlier."
- Jea...
- Taken for 1 to 2 years
- March 10, 2025
Adalimumab "I was on Rinvoq for a little over a year, and my WBC started dropping, and I was getting frequent UTIs. So my doctor switched me to Humira. I was on it for four months, and the whole time was not feeling that great. But I also have other issues, so I thought it was those issues popping up. I get a follow-up VECTRA done four months in, only to find out my VECTRA score had increased by 20 points in that short time period, and the Humira was not working. Have no clue why, because TNF blockers are supposed to be a superior form of treatment. Switched back to Rinvoq, feeling much better, and it turns out the Humira not working was the reason why I was not feeling well. Taking zinc, whole food vitamin C, and vitamin E to try and support my immune system, to hopefully avert a repeat of last time."
- RHK...
- Taken for 2 to 5 years
- March 11, 2025
Adalimumab "Pretty good experience so far. 2+ years. Having right arm elbow pain and stiffness right now. After 2 days, getting a little better. All in all, much better than prior. Had attacks that confined me to a chair for a week at a time."
- Rel...
- Taken for 2 to 5 years
- March 19, 2025
Adalimumab "I was diagnosed with JRA when I was 14. Over the years, I have tried many forms of medications: Gold, penicillamine, and no relief. My rheumatology doctor prescribed Humira 3 years ago, and it has worked extremely well. I am on the AbbVie program where they send it directly to me at no charge. It’s a special pharmacy, and my income allowed me to get it at $0 cost. I am one of the blessed ones with no side effects at all. Some that do have issues may have had other health issues. Don’t let the adverse responses dictate a trial run."
Are you taking this medicine?
Your review helps others make informed decisions.Learn more about Rheumatoid Arthritis
Care guides
Symptoms and treatments
Medicine.com guides (external)
More about adalimumab
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (738)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: antirheumatics
- Breastfeeding
Patient resources
- Adalimumab drug information
- Adalimumab-aacf (Advanced Reading)
- Adalimumab-aaty (Advanced Reading)
- Adalimumab-adaz (Advanced Reading)
- Adalimumab-adbm (Advanced Reading)
Other brands
Humira, Amjevita, Hadlima, Hyrimoz, ... +7 more
Professional resources
- Adalimumab monograph
- Adalimumab Injection (FDA)
- Adalimumab-aacf (FDA)
- Adalimumab-adaz (FDA)
- Adalimumab-adbm (FDA)
- Adalimumab-ryvk (FDA)
Other brands
Humira, Amjevita, Hadlima, Hyrimoz, ... +7 more
Adalimumab "I have been on Humira since 2007, 14 years and 4 months. It took over 2 years for me to be diagnosed with RA. I went from a jogger, hiker, water skier to someone who could barely walk from my car into my office building, needed both hands to turn my car key in the ignition due to pain, swollen and painful fingers and feet. Felt like I hardly had a life. After 6 months on Methotrexate, my doctor put me on Humira. Within a few months, I was back to running, hiking in the mountains, and water skiing- I had my life back! I am rarely ill and have only had one bad sinus infection in the years on Humira. It's worked very well for me."