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Acetaminophen / diphenhydramine User Reviews & Ratings (Page 2)

Brand names: Tylenol PM, Headache Relief PM, Pain Reliever PM, Midol PM, Percogesic Extra Strength, Headache Formula PM, Legatrin PM, Bayer Select Max Strength Night Time Pain, ConRx PM, Acetadryl, Night Time Pain, Percogesic Original Strength, Unisom PM Pain, Genapap PM, Mapap PM, Counteract PM Extra Strength, Wal-Nadol PM Extra Strength, Excedrin PM, Tylenol Sore Throat Nighttime, Pharbetol PM, Non-Aspirin PM Extra Strength Acetaminophen PM Extra Strength Robitussin Honey Severe Cough, Flu + Sore Throat CF Max Nighttime Anacin PM Aspirin Free …show all brand names

Acetaminophen / diphenhydramine has an average rating of 7.1 out of 10 from a total of 69 reviews on Drugs.com. 67% of reviewers reported a positive experience, while 25% reported a negative experience.

Reviews for Acetaminophen / diphenhydramine

Commonly mentioned side effects
  • Anonymous
  • March 22, 2009

Acetaminophen / diphenhydramine for Headache "I occasionally use Tylenol Rapid Release during the day and recently developed a cold and flu, so I decided to try Tylenol PM at night for better sleep. Make sure to read the drug interactions first, as I spent two restless nights with nervousness. Many of my friends take this product, so I'll pass it on to them, but if you are on other medication, check the list of side effects."

1 / 10
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14 Report
  • car...
  • November 20, 2012

Acetaminophen / diphenhydramine for Headache "I have severe migraines, and Percogesic over-the-counter helps like no prescription medicine. I first tried this from a sample at a chemist in 1973. I have kept it in my cabinet since. Now I cannot find it. My bottle is out of date and I am so worried."

10 / 10
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10 Report
  • Beb...
  • August 30, 2013

Acetaminophen / diphenhydramine for Headache "They also have the extra strength Percogesic. I love it. I keep a bottle in my purse all the time. My doctor is afraid to write a prescription for anything stronger than Tylenol, so I have to depend on the Percogesic for my very frequent headaches!"

10 / 10
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11 Report
  • Whi...
  • March 19, 2008

Acetaminophen / diphenhydramine for Headache "I get severe headaches and occasional migraines. Percogesic seems to be the ONLY thing that helps with the pain. I've tried prescription medications for treating migraines, including Imitrex and others. Nothing seemed to help as much as the Percogesic. Another good thing is that I don't experience any terrible side effects like I have with migraine medications. I'd highly recommend this. I also take it a few times per year (at most) to ease my cramps during my period when the pain is crippling."

10 / 10
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15 Report
  • Lyg...
  • Taken for 6 months to 1 year
  • September 21, 2013

Acetaminophen / diphenhydramine for Pain "This product is not well known. I had to introduce it to my sister. She was taking Advil PM, and it made her angry, anxious. I took her off Advil PM and got her on Midol PM. A few days later, she called me and shared the same thing I experienced. Calm, well rested, relaxed, and not as angry as before. I love this product. I hate the fact that it took me so long to find it. It needs to be marketed more. Black women like me have issues with our periods. Bad cramps and insomnia plague us. A product that focuses on treating these problems without the side effects is Godsend. I take just two pills at night when I am PMSing and during my period, and I wake up like a new woman."

10 / 10
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8 Report

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  • Anonymous
  • August 16, 2008

Acetaminophen / diphenhydramine for Headache "I tried Percogesic for the first time when I had a recurring headache for 5 days. I tried everything to relieve the pain, and nothing worked. A friend told me about Percogesic, and I bought some. My headache was relieved, and I was able to sleep all night! It really works, and I would definitely recommend it!"

10 / 10
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12 Report
  • Lor...
  • October 25, 2011

Acetaminophen / diphenhydramine for Pain "Out of the vast amounts of different medicines I've taken over the years (most of which have been medicines prescribed by my physicians for severe pain, insomnia, and other chronic issues), this OTC medication is the very best for a number of conditions. I've had migraines for most of my life, but am allergic to prescription drugs for migraines. I've found that Percogesic is ideal for many problems. I have always had a high tolerance for medicines that could sedate a large farm animal, yet it is next to impossible to sedate me. Percogesic, however, has sedative properties, unlike so-called 'migraine' medicines like Excedrin Migraine. The active ingredient in Excedrin is caffeine, which is the last thing I want when I'm trying to escape pain."

9 / 10
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8 Report
  • Ang...
  • Taken for less than 1 month
  • September 8, 2019

Acetaminophen / diphenhydramine for Pain "I have taken this medication for pain in my foot due to gout. Nothing else I bought over the counter worked. I read the bottle and decided to try it. It eased my pain more than I ever thought an over-the-counter medicine could. The only thing to be aware of is it makes you sleepy and drowsy. But it works!"

10 / 10
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3 Report
  • Tri...
  • Taken for less than 1 month
  • December 30, 2021

Acetaminophen / diphenhydramine for Pain "I usually take Aleve PM for my bruised rib. My friend, a former nurse, said to use Tylenol PM so you don't get stomach bleeding. So I brought some last night. OMG, I was scratching all night, and in the morning, I felt very dizzy and disoriented. Don't know why I reacted that way, but I will never take it again. Thank you, God, that I didn't fall."

1 / 10
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1 Report
  • Anonymous
  • March 19, 2008

For Insomnia "I don't normally like to take pills for anything unless it's prescription for a real reason, but when I need to sleep, I use these. I took one the other night and it knocked me out cold, only 1. I have to cut 1 in half so I don't wake up sleeping."

10 / 10
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4 Report
  • gre...
  • January 8, 2016

Acetaminophen / diphenhydramine for Headache "I tried the cheap brands, they made me sick, so I went back to Excedrin. Works great. It's like a car - you can save and get a cheap one with cheap results or pay a little more and get something that performs great. This brand is the good one - I'd invest in their stocks."

10 / 10
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3 Report
  • emi...
  • Taken for 1 to 6 months
  • June 18, 2024

Acetaminophen / diphenhydramine for Insomnia "This medication definitely works, but it has its setbacks. I took this one night for my period cramps and I hadn't slept in about 2 days. I instantly got about almost 2 days of rest about 20 minutes after. My mom thought I had stopped breathing after a while. I woke up with the driest throat and, for some reason, a nosebleed. Something that has been irking me about this medication is the wacky and vivid dreams. My mother also has sleep problems, so she decided to take one with me last night. We both experienced vivid and disturbing dreams with the same contents within the dream. It was very trippy to hear me and my mom dreamed about being in the same place when we went to discuss how wack our nights were. Overall, this is a pretty good medication. I would not recommend it if you have asthma or have mental health issues, it will manifest in your waking life physically and emotionally."

8 / 10
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  • Chr...
  • Taken for 1 to 6 months
  • April 30, 2024

Acetaminophen / diphenhydramine "I am over aged 60 and bought Tylenol PM recently for very minor back pain that interfered with my getting proper sleep. One half of a tablet (they're not easy to break) knocked me out within 30 minutes. The small dose working so well may have to do with my age (requiring less medication) or my body weight. I am under 110 lbs. The only negative about this product is the way it affected my vision. It kicked in while I was reading, and I noticed it was suddenly quite difficult to focus on the print. However, upon waking in the morning, everything was back to normal, including my eyesight. No grogginess, either."

10 / 10
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  • Ama...
  • Taken for less than 1 month
  • February 27, 2020

Acetaminophen / diphenhydramine for Insomnia "This stuff didn't work! Kept me up all night and I was thinking one hundred thoughts per minute...."

1 / 10
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37 Report
  • Kri...
  • Taken for less than 1 month
  • August 12, 2019

Acetaminophen / diphenhydramine for Insomnia "Helped me fall asleep when I had a severe sinus infection, and helped me sleep through the night."

10 / 10
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30 Report
  • Pon...
  • Taken for less than 1 month
  • April 12, 2015

Acetaminophen / diphenhydramine for Insomnia "Amazing, made me sleep the whole night while I had insomnia. I give it a 2 thumbs up."

10 / 10
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50 Report
  • Ins...
  • Taken for less than 1 month
  • April 18, 2020

Acetaminophen / diphenhydramine for Insomnia "It made me very down, to be honest, but still, I tossed and turned for hours before I eventually got about 2 hours of sleep."

5 / 10
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20 Report
  • pat...
  • Taken for 1 to 2 years
  • March 16, 2018

Acetaminophen / diphenhydramine for Insomnia "It helps me sleep, but I still wake up and feel tired for a while."

8 / 10
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20 Report
  • Anonymous
  • January 15, 2012

Acetaminophen / diphenhydramine for Insomnia "The last several times I have taken this, I have become itchy and restless all night."

4 / 10
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36 Report
  • Jay...
  • April 20, 2016

Acetaminophen / diphenhydramine for Insomnia "Mom took it for years, and it caused her to have dementia! Do not take it long term!"

1 / 10
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40 Report
  • MOs...
  • November 23, 2019

Acetaminophen / diphenhydramine for Insomnia "Does not put me to sleep long and give my stomach an ache. I’ll stick with Benadryl."

1 / 10
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14 Report
  • Anonymous
  • September 12, 2008

Acetaminophen / diphenhydramine for Pain "Great for back pain, muscle aches, and menstrual cramps!"

10 / 10
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28 Report
  • Anonymous
  • March 11, 2008

Acetaminophen / diphenhydramine for Insomnia "It helped me fall asleep and get a full night of sleep. It was not hard for me to stop taking it. I did not wake up feeling groggy."

10 / 10
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28 Report
  • Anonymous
  • February 20, 2010

Acetaminophen / diphenhydramine for Pain "The best for back pain, cramps. It does make you sleepy, so don't drive. Helps you sleep when you're in pain. I have been taking it for years. LOVE IT!"

10 / 10
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23 Report
  • cmw...
  • October 20, 2011

Acetaminophen / diphenhydramine for Headache "I get migraines, and it's hard to get a medication that actually helps. This helps sinus headaches as well."

9 / 10
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18 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.